PMC:7271924 / 8612-9929
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T148 | 248-255 | UBERON:0000479 | denotes | tissues |
T149 | 281-291 | UBERON:0000160;CL:0002563 | denotes | intestinal |
T150 | 292-302 | CL:0002563;UBERON:0000483 | denotes | epithelial |
T151 | 303-308 | CL:0002563 | denotes | cells |
T152 | 313-324 | CL:0000542 | denotes | lymphocytes |
T153 | 366-370 | PR:000001889 | denotes | CD14 |
T154 | 377-405 | PR:000001817 | denotes | LDL receptor-related protein |
T155 | 409-414 | PR:000002058 | denotes | LRP-1 |
T156 | 415-419 | PR:000002058 | denotes | CD91 |
T157 | 439-441 | PR:000032083 | denotes | -1 |
T158 | 443-450 | PR:000032083 | denotes | omentin |
T159 | 460-480 | PR:000001153 | denotes | Toll-like receptor 2 |
T160 | 488-492 | PR:000001155 | denotes | TLR4 |
T161 | 524-529 | PR:000001208 | denotes | CXCR4 |
T162 | 581-610 | CHEBI:24499;CHEBI:24499 | denotes | heparan sulfate proteoglycans |
T163 | 630-642 | GO:0009986 | denotes | cell-surface |
T164 | 647-667 | GO:0031012 | denotes | extracellular matrix |
T165 | 668-682 | CHEBI:33839;CHEBI:33839 | denotes | macromolecules |
T166 | 752-769 | CHEBI:18085;CHEBI:18085 | denotes | glycosaminoglycan |
T167 | 834-841 | GO:0010467 | denotes | express |
T168 | 882-889 | UBERON:0000479 | denotes | tissues |
T169 | 896-908 | PR:000032083 | denotes | intelectin-1 |
T170 | 919-928 | GO:0010467 | denotes | expressed |
T171 | 941-950 | UBERON:0000160 | denotes | intestine |
T172 | 997-1002 | PR:000032083 | denotes | ITLN1 |
T173 | 1003-1009 | UBERON:0000479 | denotes | tissue |
T174 | 1104-1110 | UBERON:0000479 | denotes | tissue |
T67989 | 248-255 | UBERON:0000479 | denotes | tissues |
T35984 | 281-291 | UBERON:0000160;CL:0002563 | denotes | intestinal |
T31089 | 292-302 | CL:0002563;UBERON:0000483 | denotes | epithelial |
T66709 | 303-308 | CL:0002563 | denotes | cells |
T26829 | 313-324 | CL:0000542 | denotes | lymphocytes |
T18288 | 366-370 | PR:000001889 | denotes | CD14 |
T28580 | 377-405 | PR:000001817 | denotes | LDL receptor-related protein |
T49823 | 409-414 | PR:000002058 | denotes | LRP-1 |
T36464 | 415-419 | PR:000002058 | denotes | CD91 |
T73453 | 439-441 | PR:000032083 | denotes | -1 |
T19056 | 443-450 | PR:000032083 | denotes | omentin |
T63919 | 460-480 | PR:000001153 | denotes | Toll-like receptor 2 |
T96642 | 488-492 | PR:000001155 | denotes | TLR4 |
T33801 | 524-529 | PR:000001208 | denotes | CXCR4 |
T1184 | 581-610 | CHEBI:24499;CHEBI:24499 | denotes | heparan sulfate proteoglycans |
T34292 | 630-642 | GO:0009986 | denotes | cell-surface |
T64497 | 647-667 | GO:0031012 | denotes | extracellular matrix |
T73560 | 668-682 | CHEBI:33839;CHEBI:33839 | denotes | macromolecules |
T63923 | 752-769 | CHEBI:18085;CHEBI:18085 | denotes | glycosaminoglycan |
T69388 | 834-841 | GO:0010467 | denotes | express |
T29160 | 882-889 | UBERON:0000479 | denotes | tissues |
T19922 | 896-908 | PR:000032083 | denotes | intelectin-1 |
T81710 | 919-928 | GO:0010467 | denotes | expressed |
T59777 | 941-950 | UBERON:0000160 | denotes | intestine |
T38743 | 997-1002 | PR:000032083 | denotes | ITLN1 |
T5511 | 1003-1009 | UBERON:0000479 | denotes | tissue |
T43409 | 1104-1110 | UBERON:0000479 | denotes | tissue |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
241 | 377-407 | Gene | denotes | LDL receptor-related protein-1 | Gene:4035 |
242 | 409-414 | Gene | denotes | LRP-1 | Gene:4035 |
1477 | 460-480 | Gene | denotes | Toll-like receptor 2 | Gene:7097 |
1479 | 771-774 | Chemical | denotes | GAG | MESH:D006025 |
1481 | 752-769 | Chemical | denotes | glycosaminoglycan | MESH:D006025 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T68 | 101-106 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T69 | 248-255 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T70 | 260-264 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T71 | 281-291 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T72 | 292-308 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T73 | 303-308 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T74 | 313-324 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T75 | 377-380 | Body_part | denotes | LDL | http://purl.org/sig/ont/fma/fma63170 |
T76 | 398-405 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T77 | 503-511 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T78 | 581-610 | Body_part | denotes | heparan sulfate proteoglycans | http://purl.org/sig/ont/fma/fma82834 |
T79 | 581-596 | Body_part | denotes | heparan sulfate | http://purl.org/sig/ont/fma/fma63023 |
T80 | 612-617 | Body_part | denotes | HSPGs | http://purl.org/sig/ont/fma/fma82834 |
T81 | 630-642 | Body_part | denotes | cell-surface | http://purl.org/sig/ont/fma/fma67653 |
T82 | 630-634 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T83 | 647-667 | Body_part | denotes | extracellular matrix | http://purl.org/sig/ont/fma/fma9672 |
T84 | 711-718 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T85 | 752-769 | Body_part | denotes | glycosaminoglycan | http://purl.org/sig/ont/fma/fma63011 |
T86 | 771-774 | Body_part | denotes | GAG | http://purl.org/sig/ont/fma/fma63011 |
T87 | 882-889 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T88 | 941-950 | Body_part | denotes | intestine | http://purl.org/sig/ont/fma/fma7199 |
T89 | 1003-1009 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
T90 | 1104-1110 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T24 | 941-950 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/UBERON_0000160 |
T25 | 1003-1009 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T26 | 1104-1110 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T104 | 43-53 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
T105 | 101-106 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T106 | 260-270 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T107 | 281-291 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T108 | 281-291 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T109 | 292-302 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T110 | 303-308 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T111 | 581-610 | http://purl.obolibrary.org/obo/PR_000001307 | denotes | heparan sulfate proteoglycans |
T112 | 612-617 | http://purl.obolibrary.org/obo/PR_000001307 | denotes | HSPGs |
T113 | 630-634 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T114 | 704-705 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T115 | 941-950 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestine |
T116 | 941-950 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestine |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T111 | 0-2 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T112 | 131-133 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T113 | 355-357 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T114 | 377-380 | Chemical | denotes | LDL | http://purl.obolibrary.org/obo/CHEBI_39026 |
T115 | 398-405 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T116 | 564-566 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T117 | 581-596 | Chemical | denotes | heparan sulfate | http://purl.obolibrary.org/obo/CHEBI_28815 |
T118 | 581-588 | Chemical | denotes | heparan | http://purl.obolibrary.org/obo/CHEBI_24500 |
T119 | 589-596 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
T120 | 597-610 | Chemical | denotes | proteoglycans | http://purl.obolibrary.org/obo/CHEBI_37396 |
T121 | 668-682 | Chemical | denotes | macromolecules | http://purl.obolibrary.org/obo/CHEBI_33839 |
T122 | 711-718 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T123 | 752-769 | Chemical | denotes | glycosaminoglycan | http://purl.obolibrary.org/obo/CHEBI_18085 |
T124 | 771-774 | Chemical | denotes | GAG | http://purl.obolibrary.org/obo/CHEBI_143889|http://purl.obolibrary.org/obo/CHEBI_18085 |
T126 | 1199-1201 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16 | 377-389 | http://purl.obolibrary.org/obo/GO_0005041 | denotes | LDL receptor |
T17 | 524-529 | http://purl.obolibrary.org/obo/GO_0038147 | denotes | CXCR4 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T68 | 0-107 | Sentence | denotes | LF is thought to exert its main biological activities following interaction with receptors on target cells. |
T69 | 108-211 | Sentence | denotes | There are in fact many LF receptors, though sometimes one is referred to as “the” lactoferrin receptor. |
T70 | 212-334 | Sentence | denotes | They have been detected in multiple tissues and cell types including intestinal epithelial cells and lymphocytes (60, 61). |
T71 | 335-550 | Sentence | denotes | Receptors that bind LF include CD14 (62), LDL receptor-related protein-1 (LRP-1/CD91) (63–65) intelectin-1 (omentin-1) (66), Toll-like receptor 2 and 4 (TLR4) (67) and cytokine receptor 4 (CXCR4) (68) (see Table 2). |
T72 | 551-800 | Sentence | denotes | Importantly, LF also binds to heparan sulfate proteoglycans (HSPGs), which are cell-surface and extracellular matrix macromolecules that are composed of a core protein decorated with covalently linked glycosaminoglycan (GAG) chains (86, 87, 98, 99). |
T73 | 801-813 | Sentence | denotes | See Table 2. |
T74 | 814-1111 | Sentence | denotes | Different receptors express at vastly different levels in different tissues; thus intelectin-1 is really expressed only in the intestine (https://www.proteinatlas.org/ENSG00000179914-ITLN1/tissue), while LRP1 is far more widely distributed https://www.proteinatlas.org/ENSG00000123384-LRP1/tissue. |
T75 | 1112-1317 | Sentence | denotes | These multiple receptors arguably underpin the substantial and widespread effects that LF can induce, since only when multiple targets are hit simultaneously can one normally have major effects (103, 104). |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T3 | 581-596 | GlycoEpitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-21935933-34514598 | 326-328 | 21935933 | denotes | 60 |
32574271-16261254-34514599 | 330-332 | 16261254 | denotes | 61 |
32574271-22292499-34514600 | 372-374 | 22292499 | denotes | 62 |
32574271-10066755-34514601 | 422-424 | 10066755 | denotes | 63 |
32574271-15178744-34514601 | 422-424 | 15178744 | denotes | 63 |
32574271-26506094-34514601 | 422-424 | 26506094 | denotes | 63 |
32574271-18670097-34514602 | 455-457 | 18670097 | denotes | 66 |
32574271-29410669-34514603 | 495-497 | 29410669 | denotes | 67 |
32574271-28075616-34514604 | 532-534 | 28075616 | denotes | 68 |
32574271-21690215-34514605 | 784-786 | 21690215 | denotes | 86 |
32574271-25187545-34514606 | 788-790 | 25187545 | denotes | 87 |
32574271-2849510-34514607 | 792-794 | 2849510 | denotes | 98 |
32574271-21887302-34514608 | 796-798 | 21887302 | denotes | 99 |
TEST0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-114-120-2882190 | 326-328 | ["21935933"] | denotes | 60 |
32574271-118-124-2882191 | 330-332 | ["16261254"] | denotes | 61 |
32574271-37-43-2882192 | 372-374 | ["22292499"] | denotes | 62 |
32574271-87-93-2882193 | 422-424 | ["10066755", "15178744", "26506094"] | denotes | 63 |
32574271-120-126-2882194 | 455-457 | ["18670097"] | denotes | 66 |
32574271-160-166-2882195 | 495-497 | ["29410669"] | denotes | 67 |
32574271-197-203-2882196 | 532-534 | ["28075616"] | denotes | 68 |
32574271-233-239-2882197 | 784-786 | ["21690215"] | denotes | 86 |
32574271-237-243-2882198 | 788-790 | ["25187545"] | denotes | 87 |
32574271-228-234-2882199 | 792-794 | ["2849510"] | denotes | 98 |
32574271-232-238-2882200 | 796-798 | ["21887302"] | denotes | 99 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-21935933-34514598 | 326-328 | 21935933 | denotes | 60 |
32574271-16261254-34514599 | 330-332 | 16261254 | denotes | 61 |
32574271-22292499-34514600 | 372-374 | 22292499 | denotes | 62 |
32574271-10066755-34514601 | 422-424 | 10066755 | denotes | 63 |
32574271-15178744-34514601 | 422-424 | 15178744 | denotes | 63 |
32574271-26506094-34514601 | 422-424 | 26506094 | denotes | 63 |
32574271-18670097-34514602 | 455-457 | 18670097 | denotes | 66 |
32574271-29410669-34514603 | 495-497 | 29410669 | denotes | 67 |
32574271-28075616-34514604 | 532-534 | 28075616 | denotes | 68 |
32574271-21690215-34514605 | 784-786 | 21690215 | denotes | 86 |
32574271-25187545-34514606 | 788-790 | 25187545 | denotes | 87 |
32574271-2849510-34514607 | 792-794 | 2849510 | denotes | 98 |
32574271-21887302-34514608 | 796-798 | 21887302 | denotes | 99 |