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PMC:7271924 / 28556-30124 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T520 0-11 PR:000009978 denotes Lactoferrin
T521 181-194 NCBITaxon:11118 denotes coronaviruses
T522 258-269 NCBITaxon:11118 denotes coronavirus
T523 346-356 SP_7 denotes SARS-CoV-2
T524 428-433 NCBITaxon:10239 denotes virus
T525 534-542 SP_10 denotes SARS-CoV
T526 562-570 SP_10 denotes SARS-CoV
T527 634-644 GO:0035376 denotes cell entry
T528 724-729 NCBITaxon:10239 denotes virus
T529 770-775 NCBITaxon:10239 denotes virus
T530 789-801 GO:0009986 denotes cell surface
T531 803-811 SP_10 denotes SARS-CoV
T532 847-860 GO:0005886 denotes cell membrane
T533 927-937 GO:0035376 denotes cell entry
T534 956-975 CL:0000623 denotes natural killer cell
T535 1000-1010 CL:0000775 denotes neutrophil
T536 1039-1045 UBERON:0002405 denotes immune
T537 1046-1053 GO:0006952 denotes defense
T538 1081-1089 GO:0035376 denotes entry of
T539 1094-1099 NCBITaxon:10239 denotes virus
T540 1185-1193 SP_7 denotes COVID-19
T541 1214-1220 GO:0007601 denotes visual
T542 1350-1354 G_3;PG_10;PR:000003622 denotes ACE2
T543 1546-1554 SP_7 denotes COVID-19
T66976 0-11 PR:000009978 denotes Lactoferrin
T92245 181-194 NCBITaxon:11118 denotes coronaviruses
T54356 258-269 NCBITaxon:11118 denotes coronavirus
T26051 346-356 SP_7 denotes SARS-CoV-2
T99342 428-433 NCBITaxon:10239 denotes virus
T68308 534-542 SP_10 denotes SARS-CoV
T39819 562-570 SP_10 denotes SARS-CoV
T81448 634-644 GO:0035376 denotes cell entry
T82315 724-729 NCBITaxon:10239 denotes virus
T15886 770-775 NCBITaxon:10239 denotes virus
T76531 789-801 GO:0009986 denotes cell surface
T49656 803-811 SP_10 denotes SARS-CoV
T95560 847-860 GO:0005886 denotes cell membrane
T81157 927-937 GO:0035376 denotes cell entry
T16593 956-975 CL:0000623 denotes natural killer cell
T26835 1000-1010 CL:0000775 denotes neutrophil
T92368 1039-1045 UBERON:0002405 denotes immune
T25486 1046-1053 GO:0006952 denotes defense
T28995 1081-1089 GO:0035376 denotes entry of
T87059 1094-1099 NCBITaxon:10239 denotes virus
T26492 1185-1193 SP_7 denotes COVID-19
T46616 1214-1220 GO:0007601 denotes visual
T7529 1350-1354 G_3;PG_10;PR:000003622 denotes ACE2
T50501 1546-1554 SP_7 denotes COVID-19

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
750 0-11 Gene denotes Lactoferrin Gene:280846
751 1350-1354 Gene denotes ACE2 Gene:59272
752 1359-1363 Gene denotes HSPG Gene:6383
753 852-860 Gene denotes membrane Gene:43740571
754 181-194 Species denotes coronaviruses Tax:11118
755 346-356 Species denotes SARS-CoV-2 Tax:2697049
756 534-542 Species denotes SARS-CoV Tax:694009
757 803-811 Species denotes SARS-CoV Tax:694009
758 258-280 Disease denotes coronavirus infections MESH:D018352
759 478-487 Disease denotes infection MESH:D007239
760 562-581 Disease denotes SARS-CoV infections MESH:C000657245
761 1123-1132 Disease denotes infection MESH:D007239
762 1185-1193 Disease denotes COVID-19 MESH:C000657245
763 1546-1554 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T322 387-392 Body_part denotes HSPGs http://purl.org/sig/ont/fma/fma82834
T323 443-448 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T324 494-499 Body_part denotes HSPGs http://purl.org/sig/ont/fma/fma82834
T325 587-592 Body_part denotes HSPGs http://purl.org/sig/ont/fma/fma82834
T326 634-638 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T327 683-688 Body_part denotes HSPGs http://purl.org/sig/ont/fma/fma82834
T328 739-744 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T329 789-801 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T330 789-793 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T331 821-826 Body_part denotes HSPGs http://purl.org/sig/ont/fma/fma82834
T332 847-860 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T333 847-851 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T334 927-931 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T335 956-975 Body_part denotes natural killer cell http://purl.org/sig/ont/fma/fma63147
T336 971-975 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T337 1000-1010 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T338 1110-1115 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T339 1359-1363 Body_part denotes HSPG http://purl.org/sig/ont/fma/fma82834

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T104 270-280 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T105 346-354 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 478-487 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T107 534-542 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T108 562-570 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T109 571-581 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T110 803-811 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T111 1123-1132 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T112 1185-1193 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T113 1546-1554 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T379 20-23 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T380 297-298 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T381 387-392 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPGs
T382 428-433 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T383 443-448 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T384 494-499 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPGs
T385 587-592 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPGs
T386 634-638 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T387 683-688 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPGs
T388 724-729 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T389 739-744 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T390 770-775 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T391 789-793 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T392 821-826 http://purl.obolibrary.org/obo/PR_000001307 denotes HSPGs
T393 847-851 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T394 852-860 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T395 927-931 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T396 956-975 http://purl.obolibrary.org/obo/CL_0000623 denotes natural killer cell
T397 976-984 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T398 1094-1099 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T399 1110-1115 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T400 1212-1213 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T401 1328-1329 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T402 1479-1480 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T403 1523-1524 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T354 97-106 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T355 322-324 Chemical denotes LF http://purl.obolibrary.org/obo/CHEBI_73585
T356 381-383 Chemical denotes LF http://purl.obolibrary.org/obo/CHEBI_73585
T357 944-946 Chemical denotes LF http://purl.obolibrary.org/obo/CHEBI_73585
T358 1414-1416 Chemical denotes LF http://purl.obolibrary.org/obo/CHEBI_73585

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T64 956-984 http://purl.obolibrary.org/obo/GO_0030101 denotes natural killer cell activity
T65 1000-1022 http://purl.obolibrary.org/obo/GO_0070488 denotes neutrophil aggregation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T224 0-112 Sentence denotes Lactoferrin clearly has immunological benefits, as well as having an important antibacterial and antiviral role.
T225 113-281 Sentence denotes Because it is known to interfere with some of the receptors used by coronaviruses, it may contribute usefully to the prevention and treatment of coronavirus infections.
T226 282-365 Sentence denotes Figure 6 shows a possible scheme on how LF might interfere with SARS-CoV-2 binding.
T227 366-493 Sentence denotes The binding of LF to HSPGs prevents the first contact between virus and host cells and thus prevents subsequent infection (99).
T228 494-549 Sentence denotes HSPGs themselves are not sufficient for SARS-CoV entry.
T229 550-650 Sentence denotes However, in SARS-CoV infections, the HSPGs play an important role in the process of cell entry (99).
T230 651-802 Sentence denotes The anchoring sites provided by HSPGs permit initial contact between the virus and host cells and the concentration of virus particles on cell surface.
T231 803-943 Sentence denotes SARS-CoV bound to HSPGs then rolls onto the cell membrane and scans for specific entry receptors, which leads to subsequent cell entry (99).
T232 944-1133 Sentence denotes LF enhances natural killer cell activity and stimulates neutrophil aggregation and adhesion in immune defense (135) and can restrict the entry of the virus into host cells during infection.
T233 1134-1302 Sentence denotes We suggest that this process might be the same for COVID-19 (see Figure 6 for a visual representation), thereby offering useful strategies for prevention and treatment.
T234 1303-1413 Sentence denotes Currently, there is also a renewed interest in ACE2 and HSPG blocking, as discussed in the introduction (5–8).
T235 1414-1568 Sentence denotes LF may therefore be an excellent supplement to take, not only as a contribution to prevention but perhaps as a therapy in the event COVID-19 is diagnosed.

MyTest

Id Subject Object Predicate Lexical cue
32574271-21887302-34514761 489-491 21887302 denotes 99
32574271-21887302-34514762 646-648 21887302 denotes 99
32574271-21887302-34514763 939-941 21887302 denotes 99
32574271-15655079-34514764 1055-1058 15655079 denotes 135
32574271-32228252-34514765 1408-1409 32228252 denotes 5
32574271-32334062-34514765 1408-1409 32334062 denotes 5
32574271-32333836-34514765 1408-1409 32333836 denotes 5
32574271-32395702-34514765 1408-1409 32395702 denotes 5

TEST0

Id Subject Object Predicate Lexical cue
32574271-123-129-2882353 489-491 ["21887302"] denotes 99
32574271-96-102-2882354 646-648 ["21887302"] denotes 99
32574271-136-142-2882355 939-941 ["21887302"] denotes 99
32574271-111-118-2882356 1055-1058 ["15655079"] denotes 135
32574271-105-110-2882357 1408-1409 ["32228252", "32334062", "32333836", "32395702"] denotes 5

2_test

Id Subject Object Predicate Lexical cue
32574271-21887302-34514761 489-491 21887302 denotes 99
32574271-21887302-34514762 646-648 21887302 denotes 99
32574271-21887302-34514763 939-941 21887302 denotes 99
32574271-15655079-34514764 1055-1058 15655079 denotes 135
32574271-32228252-34514765 1408-1409 32228252 denotes 5
32574271-32334062-34514765 1408-1409 32334062 denotes 5
32574271-32333836-34514765 1408-1409 32333836 denotes 5
32574271-32395702-34514765 1408-1409 32395702 denotes 5