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PMC:7271924 / 22359-24331 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T448 93-103 SP_7 denotes SARS-CoV-2
T449 113-122 CL:0000233 denotes platelets
T450 150-158 SP_7 denotes COVID-19
T451 248-257 NCBITaxon:7719 denotes influenza
T452 258-263 NCBITaxon:10239 denotes virus
T453 268-279 NCBITaxon:7745 denotes Francisella
T454 280-290 NCBITaxon:10665 denotes tularensis
T455 303-307 UBERON:0000104 denotes life
T456 391-400 CL:0000233 denotes platelets
T457 405-414 CL:0000233 denotes platelets
T458 447-459 CHEBI:67079;CHEBI:67079 denotes inflammatory
T459 460-469 CHEBI:36357;CHEBI:36357 denotes molecules
T460 559-568 CL:0000233 denotes platelets
T461 582-590 CL:0000233 denotes platelet
T462 763-771 SP_7 denotes COVID-19
T463 987-1003 GO:0050817 denotes hypercoagulation
T464 1010-1018 SP_7 denotes COVID-19
T465 1238-1243 UBERON:0001977 denotes serum
T466 1254-1258 PR:000001393 denotes IL-6
T467 1260-1278 PR:000005897 denotes C-reactive protein
T468 1280-1285 UBERON:0001977 denotes serum
T469 1532-1540 SP_7 denotes COVID-19
T470 1554-1563 UBERON:0002048 denotes pulmonary
T471 1599-1607 SP_7 denotes COVID-19
T472 1647-1656 CL:0002627 denotes activated
T473 1657-1666 CL:0000233 denotes platelets
T474 1739-1748 UBERON:0002048 denotes pulmonary
T475 1780-1793 GO:0050817 denotes anticoagulant
T476 1829-1836 CHEBI:24505;CHEBI:24505 denotes heparin
T477 1875-1882 CHEBI:24505;CHEBI:24505 denotes heparin
T478 1948-1956 SP_7 denotes COVID-19
T43446 93-103 SP_7 denotes SARS-CoV-2
T51405 113-122 CL:0000233 denotes platelets
T88556 150-158 SP_7 denotes COVID-19
T83394 248-257 NCBITaxon:7719 denotes influenza
T98944 258-263 NCBITaxon:10239 denotes virus
T15104 268-279 NCBITaxon:7745 denotes Francisella
T80003 280-290 NCBITaxon:10665 denotes tularensis
T85415 303-307 UBERON:0000104 denotes life
T15011 391-400 CL:0000233 denotes platelets
T88071 405-414 CL:0000233 denotes platelets
T99469 447-459 CHEBI:67079;CHEBI:67079 denotes inflammatory
T82005 460-469 CHEBI:36357;CHEBI:36357 denotes molecules
T45502 559-568 CL:0000233 denotes platelets
T34676 582-590 CL:0000233 denotes platelet
T23337 763-771 SP_7 denotes COVID-19
T83958 987-1003 GO:0050817 denotes hypercoagulation
T55973 1010-1018 SP_7 denotes COVID-19
T98889 1238-1243 UBERON:0001977 denotes serum
T92738 1254-1258 PR:000001393 denotes IL-6
T32605 1260-1278 PR:000005897 denotes C-reactive protein
T15602 1280-1285 UBERON:0001977 denotes serum
T75440 1532-1540 SP_7 denotes COVID-19
T53426 1554-1563 UBERON:0002048 denotes pulmonary
T30131 1599-1607 SP_7 denotes COVID-19
T16280 1647-1656 CL:0002627 denotes activated
T20176 1657-1666 CL:0000233 denotes platelets
T13751 1739-1748 UBERON:0002048 denotes pulmonary
T76458 1780-1793 GO:0050817 denotes anticoagulant
T46556 1829-1836 CHEBI:24505;CHEBI:24505 denotes heparin
T17255 1875-1882 CHEBI:24505;CHEBI:24505 denotes heparin
T12103 1948-1956 SP_7 denotes COVID-19

LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1829-1836 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T2 1829-1836 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T3 1875-1882 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 1875-1882 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
601 1254-1258 Gene denotes IL-6 Gene:3569
602 1260-1278 Gene denotes C-reactive protein Gene:1401
603 93-103 Species denotes SARS-CoV-2 Tax:2697049
604 248-263 Species denotes influenza virus Tax:11308
605 268-290 Species denotes Francisella tularensis Tax:263
606 749-757 Species denotes patients Tax:9606
607 867-875 Species denotes Patients Tax:9606
608 1019-1027 Species denotes patients Tax:9606
609 1347-1355 Species denotes patients Tax:9606
610 1401-1409 Species denotes patients Tax:9606
611 1519-1526 Species denotes patient Tax:9606
612 1957-1965 Species denotes patients Tax:9606
613 1829-1836 Chemical denotes heparin MESH:D006493
614 1854-1882 Chemical denotes low molecular weight heparin MESH:D006495
615 150-158 Disease denotes COVID-19 MESH:C000657245
616 159-168 Disease denotes infection MESH:D007239
617 598-614 Disease denotes thrombocytopenia MESH:D013921
618 645-661 Disease denotes hypercoagulation MESH:D019851
619 663-679 Disease denotes Thrombocytopenia MESH:D013921
620 736-745 Disease denotes mortality MESH:D003643
621 763-771 Disease denotes COVID-19 MESH:C000657245
622 888-896 Disease denotes diabetes MESH:D003920
623 987-1003 Disease denotes hypercoagulation MESH:D019851
624 1010-1018 Disease denotes COVID-19 MESH:C000657245
625 1065-1073 Disease denotes diabetes MESH:D003920
626 1103-1112 Disease denotes pneumonia MESH:D011014
627 1338-1346 Disease denotes diabetic MESH:D003920
628 1415-1423 Disease denotes diabetes MESH:D003920
629 1532-1540 Disease denotes COVID-19 MESH:C000657245
630 1554-1572 Disease denotes pulmonary embolism MESH:D011655
631 1599-1607 Disease denotes COVID-19 MESH:C000657245
632 1608-1617 Disease denotes infection MESH:D007239
633 1678-1688 Disease denotes oedematous
634 1739-1757 Disease denotes pulmonary embolism MESH:D011655
635 1948-1956 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T276 113-122 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T277 207-215 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T278 320-328 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T279 350-358 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T280 391-400 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T281 405-414 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T282 513-522 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T283 559-568 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T284 582-590 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T285 973-982 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T286 1238-1243 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T287 1254-1256 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T288 1271-1278 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T289 1280-1285 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T290 1657-1666 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T291 1829-1836 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T292 1875-1882 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T51 1238-1243 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T52 1280-1285 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T61 93-101 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 150-158 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 159-168 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T64 248-257 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T65 598-614 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T66 663-679 Disease denotes Thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T67 763-771 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 881-896 Disease denotes type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148
T69 888-896 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T70 1010-1018 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 1065-1073 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T72 1103-1112 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T73 1166-1181 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T74 1415-1423 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T75 1532-1540 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 1554-1572 Disease denotes pulmonary embolism http://purl.obolibrary.org/obo/MONDO_0005279
T77 1599-1607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 1608-1617 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T79 1739-1757 Disease denotes pulmonary embolism http://purl.obolibrary.org/obo/MONDO_0005279
T80 1948-1956 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T323 205-206 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T324 258-263 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T325 348-349 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 621-622 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T327 1164-1165 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 1573-1576 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T329 1647-1656 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T301 460-469 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T302 801-810 Chemical denotes indicator http://purl.obolibrary.org/obo/CHEBI_47867
T303 1195-1198 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T304 1254-1256 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072|http://purl.obolibrary.org/obo/CHEBI_52998
T307 1271-1278 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T308 1780-1793 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T309 1829-1836 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T310 1875-1882 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T53 1137-1159 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T175 0-123 Sentence denotes Of particular interest, and in the context of this paper, is the set of interactions between SARS-CoV-2 and host platelets.
T176 124-228 Sentence denotes This is of importance, as COVID-19 infection, can cause hyperinflammation due to a cytokine storm (166).
T177 229-342 Sentence denotes Pathogens like the influenza virus and Francisella tularensis, do trigger life-threatening cytokine storms (173).
T178 343-500 Sentence denotes Such a cytokine storm will significantly affect platelets, as platelets have many receptors where these inflammatory molecules may bind (173) (see Figure 5).
T179 501-662 Sentence denotes Circulating cytokines and inflammagens will hyperactivate platelets, causing low platelet count (thrombocytopenia), and a significant chance of hypercoagulation.
T180 663-866 Sentence denotes Thrombocytopenia is associated with increased risk of severe disease and mortality in patients with COVID-19, and thus serves as clinical indicator of worsening illness during hospitalization (174, 175).
T181 867-1009 Sentence denotes Patients with type 2 diabetes are also particularly prone to increased levels of circulating inflammatory cytokines and hypercoagulation (76).
T182 1010-1194 Sentence denotes COVID-19 patients without other comorbidities but with diabetes are at higher risk of severe pneumonia, excessive uncontrolled inflammatory responses and a hypercoagulable state (176).
T183 1195-1547 Sentence denotes Guo and co-workers in 2020 also found that serum levels of IL-6, C-reactive protein, serum ferritin, and D-dimer, were significantly higher in diabetic patients compared with those without, suggesting that patients with diabetes are more susceptible to an inflammatory storm eventually leading to rapid deterioration of the patient with COVID-19 (140).
T184 1548-1624 Sentence denotes Acute pulmonary embolism has also been reported in COVID-19 infection (177).
T185 1625-1764 Sentence denotes Focal accumulation of activated platelets within the oedematous area ex vivo correlated well with the size of the pulmonary embolism (178).
T186 1765-1972 Sentence denotes Interestingly, anticoagulant therapy, mainly with (intravenous) heparin (and mainly with low molecular weight heparin, LMWH), appears to be associated with better prognosis in severe COVID-19 patients (179).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T14 207-221 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T15 320-335 Phenotype denotes cytokine storms http://purl.obolibrary.org/obo/HP_0033041
T16 350-364 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T17 578-596 Phenotype denotes low platelet count http://purl.obolibrary.org/obo/HP_0001873
T18 598-614 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T19 663-679 Phenotype denotes Thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T20 881-896 Phenotype denotes type 2 diabetes http://purl.obolibrary.org/obo/HP_0005978
T21 1103-1112 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T22 1554-1572 Phenotype denotes pulmonary embolism http://purl.obolibrary.org/obo/HP_0002204
T23 1739-1757 Phenotype denotes pulmonary embolism http://purl.obolibrary.org/obo/HP_0002204

MyTest

Id Subject Object Predicate Lexical cue
32574271-32192578-34514729 223-226 32192578 denotes 166
32574271-23283640-34514730 337-340 23283640 denotes 173
32574271-23283640-34514731 480-483 23283640 denotes 173
32574271-32178975-34514732 856-859 32178975 denotes 174
32574271-32216803-34514733 861-864 32216803 denotes 175
32574271-31196615-34514734 1005-1007 31196615 denotes 76
32574271-28990587-34514735 1542-1545 28990587 denotes 140
32574271-32227120-34514736 1619-1622 32227120 denotes 177
32574271-27138487-34514737 1759-1762 27138487 denotes 178
32574271-32220112-34514738 1967-1970 32220112 denotes 179

TEST0

Id Subject Object Predicate Lexical cue
32574271-99-106-2882321 223-226 ["32192578"] denotes 166
32574271-108-115-2882322 337-340 ["23283640"] denotes 173
32574271-137-144-2882323 480-483 ["23283640"] denotes 173
32574271-193-200-2882324 856-859 ["32178975"] denotes 174
32574271-198-205-2882325 861-864 ["32216803"] denotes 175
32574271-138-144-2882326 1005-1007 ["31196615"] denotes 76
32574271-233-240-2882327 1542-1545 ["28990587"] denotes 140
32574271-71-78-2882328 1619-1622 ["32227120"] denotes 177
32574271-134-141-2882329 1759-1762 ["27138487"] denotes 178
32574271-202-209-2882330 1967-1970 ["32220112"] denotes 179

2_test

Id Subject Object Predicate Lexical cue
32574271-32192578-34514729 223-226 32192578 denotes 166
32574271-23283640-34514730 337-340 23283640 denotes 173
32574271-23283640-34514731 480-483 23283640 denotes 173
32574271-32178975-34514732 856-859 32178975 denotes 174
32574271-32216803-34514733 861-864 32216803 denotes 175
32574271-31196615-34514734 1005-1007 31196615 denotes 76
32574271-28990587-34514735 1542-1545 28990587 denotes 140
32574271-32227120-34514736 1619-1622 32227120 denotes 177
32574271-27138487-34514737 1759-1762 27138487 denotes 178
32574271-32220112-34514738 1967-1970 32220112 denotes 179