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LitCovid-PMC-OGER-BB

LitCovid-PubTator

{"project":"LitCovid-PubTator","denotations":[{"id":"550","span":{"begin":119,"end":123},"obj":"Gene"},{"id":"551","span":{"begin":372,"end":376},"obj":"Gene"},{"id":"552","span":{"begin":393,"end":397},"obj":"Gene"},{"id":"553","span":{"begin":905,"end":909},"obj":"Gene"},{"id":"554","span":{"begin":9,"end":17},"obj":"Species"},{"id":"555","span":{"begin":330,"end":340},"obj":"Species"},{"id":"556","span":{"begin":421,"end":426},"obj":"Species"},{"id":"557","span":{"begin":688,"end":696},"obj":"Species"},{"id":"558","span":{"begin":761,"end":771},"obj":"Species"},{"id":"559","span":{"begin":824,"end":832},"obj":"Species"},{"id":"560","span":{"begin":951,"end":961},"obj":"Species"},{"id":"561","span":{"begin":1031,"end":1039},"obj":"Species"},{"id":"562","span":{"begin":152,"end":160},"obj":"Gene"},{"id":"563","span":{"begin":310,"end":318},"obj":"Disease"},{"id":"564","span":{"begin":319,"end":328},"obj":"Disease"},{"id":"565","span":{"begin":797,"end":820},"obj":"Disease"}],"attributes":[{"id":"A550","pred":"tao:has_database_id","subj":"550","obj":"Gene:59272"},{"id":"A551","pred":"tao:has_database_id","subj":"551","obj":"Gene:59272"},{"id":"A552","pred":"tao:has_database_id","subj":"552","obj":"Gene:59272"},{"id":"A553","pred":"tao:has_database_id","subj":"553","obj":"Gene:59272"},{"id":"A554","pred":"tao:has_database_id","subj":"554","obj":"Tax:694009"},{"id":"A555","pred":"tao:has_database_id","subj":"555","obj":"Tax:2697049"},{"id":"A556","pred":"tao:has_database_id","subj":"556","obj":"Tax:9606"},{"id":"A557","pred":"tao:has_database_id","subj":"557","obj":"Tax:694009"},{"id":"A558","pred":"tao:has_database_id","subj":"558","obj":"Tax:2697049"},{"id":"A559","pred":"tao:has_database_id","subj":"559","obj":"Tax:694009"},{"id":"A560","pred":"tao:has_database_id","subj":"560","obj":"Tax:2697049"},{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"Tax:694009"},{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"Gene:43740571"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"MESH:C000657245"},{"id":"A564","pred":"tao:has_database_id","subj":"564","obj":"MESH:D007239"},{"id":"A565","pred":"tao:has_database_id","subj":"565","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T46","span":{"begin":278,"end":295},"obj":"Body_part"},{"id":"T47","span":{"begin":427,"end":431},"obj":"Body_part"},{"id":"T48","span":{"begin":478,"end":493},"obj":"Body_part"},{"id":"T49","span":{"begin":484,"end":493},"obj":"Body_part"},{"id":"T50","span":{"begin":553,"end":559},"obj":"Body_part"}],"attributes":[{"id":"A46","pred":"uberon_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"id":"A47","pred":"uberon_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A48","pred":"uberon_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"A49","pred":"uberon_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A50","pred":"uberon_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T50","span":{"begin":9,"end":17},"obj":"Disease"},{"id":"T51","span":{"begin":43,"end":76},"obj":"Disease"},{"id":"T52","span":{"begin":310,"end":318},"obj":"Disease"},{"id":"T53","span":{"begin":319,"end":328},"obj":"Disease"},{"id":"T54","span":{"begin":330,"end":338},"obj":"Disease"},{"id":"T55","span":{"begin":688,"end":696},"obj":"Disease"},{"id":"T56","span":{"begin":761,"end":769},"obj":"Disease"},{"id":"T57","span":{"begin":811,"end":820},"obj":"Disease"},{"id":"T58","span":{"begin":824,"end":832},"obj":"Disease"},{"id":"T59","span":{"begin":951,"end":959},"obj":"Disease"},{"id":"T60","span":{"begin":1031,"end":1039},"obj":"Disease"}],"attributes":[{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A55","pred":"mondo_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A56","pred":"mondo_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A57","pred":"mondo_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A59","pred":"mondo_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A60","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

LitCovid-PD-CLO

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T301","span":{"begin":95,"end":100},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T302","span":{"begin":152,"end":160},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T303","span":{"begin":181,"end":182},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T304","span":{"begin":219,"end":226},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T305","span":{"begin":358,"end":363},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T306","span":{"begin":421,"end":426},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T307","span":{"begin":427,"end":431},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T308","span":{"begin":427,"end":431},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T309","span":{"begin":441,"end":451},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T310","span":{"begin":452,"end":457},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T311","span":{"begin":478,"end":493},"obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"T312","span":{"begin":540,"end":545},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T313","span":{"begin":553,"end":559},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T314","span":{"begin":553,"end":559},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T315","span":{"begin":553,"end":559},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T316","span":{"begin":566,"end":571},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T317","span":{"begin":630,"end":634},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T318","span":{"begin":697,"end":701},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T319","span":{"begin":781,"end":786},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T320","span":{"begin":847,"end":852},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T321","span":{"begin":931,"end":936},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T322","span":{"begin":979,"end":984},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

LitCovid-PD-CHEBI

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T298","span":{"begin":161,"end":168},"obj":"Chemical"},{"id":"T299","span":{"begin":797,"end":799},"obj":"Chemical"},{"id":"T300","span":{"begin":893,"end":895},"obj":"Chemical"}],"attributes":[{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_73585"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_73585"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T167","span":{"begin":0,"end":130},"obj":"Sentence"},{"id":"T168","span":{"begin":131,"end":302},"obj":"Sentence"},{"id":"T169","span":{"begin":303,"end":392},"obj":"Sentence"},{"id":"T170","span":{"begin":393,"end":565},"obj":"Sentence"},{"id":"T171","span":{"begin":566,"end":713},"obj":"Sentence"},{"id":"T172","span":{"begin":714,"end":858},"obj":"Sentence"},{"id":"T173","span":{"begin":859,"end":942},"obj":"Sentence"},{"id":"T174","span":{"begin":943,"end":1079},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

MyTest

{"project":"MyTest","denotations":[{"id":"32574271-31996437-34514722","span":{"begin":125,"end":128},"obj":"31996437"},{"id":"32574271-29142129-34514723","span":{"begin":297,"end":300},"obj":"29142129"},{"id":"32574271-32167747-34514724","span":{"begin":387,"end":390},"obj":"32167747"},{"id":"32574271-21887302-34514725","span":{"begin":561,"end":563},"obj":"21887302"},{"id":"32574271-21887302-34514726","span":{"begin":709,"end":711},"obj":"21887302"},{"id":"32574271-21887302-34514727","span":{"begin":854,"end":856},"obj":"21887302"},{"id":"32574271-21887302-34514728","span":{"begin":938,"end":940},"obj":"21887302"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

TEST0

{"project":"TEST0","denotations":[{"id":"32574271-125-132-2882314","span":{"begin":125,"end":128},"obj":"[\"31996437\"]"},{"id":"32574271-166-173-2882315","span":{"begin":297,"end":300},"obj":"[\"29142129\"]"},{"id":"32574271-84-91-2882316","span":{"begin":387,"end":390},"obj":"[\"32167747\"]"},{"id":"32574271-168-174-2882317","span":{"begin":561,"end":563},"obj":"[\"21887302\"]"},{"id":"32574271-143-149-2882318","span":{"begin":709,"end":711},"obj":"[\"21887302\"]"},{"id":"32574271-140-146-2882319","span":{"begin":854,"end":856},"obj":"[\"21887302\"]"},{"id":"32574271-79-85-2882320","span":{"begin":938,"end":940},"obj":"[\"21887302\"]"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

2_test

{"project":"2_test","denotations":[{"id":"32574271-31996437-34514722","span":{"begin":125,"end":128},"obj":"31996437"},{"id":"32574271-29142129-34514723","span":{"begin":297,"end":300},"obj":"29142129"},{"id":"32574271-32167747-34514724","span":{"begin":387,"end":390},"obj":"32167747"},{"id":"32574271-21887302-34514725","span":{"begin":561,"end":563},"obj":"21887302"},{"id":"32574271-21887302-34514726","span":{"begin":709,"end":711},"obj":"21887302"},{"id":"32574271-21887302-34514727","span":{"begin":854,"end":856},"obj":"21887302"},{"id":"32574271-21887302-34514728","span":{"begin":938,"end":940},"obj":"21887302"}],"text":"The 2003 SARS-CoV strain, that also causes severe acute respiratory syndrome, attaches to host cells via host receptor ACE2 (171). This type I integral membrane protein receptor is a well-known receptor for respiratory viruses, and is abundantly expressed in tissues lining the respiratory tract (111). During COVID-19 infection, SARS-CoV-2 also enters host cells via the ACE2 receptor (172). ACE2 is highly expressed on human lung alveolar epithelial cells, enterocytes of the small intestine, and the brush border of the proximal tubular cells of the kidney (99). HSPGs are also one of the preliminary docking sites on the host cell surface and play an important role in the process of SARS-CoV cell entry (99). There is no current confirmed information that SARS-CoV-2 binds to HSPGs, however, LF blocks the infection of SARS-CoV by binding to HSPGs (99). It is not presently known whether LF binds to ACE2, but it does bind to HSPGs (99). Whether SARS-CoV-2 also enters host cells via HPSGs in the same way, as does (the 2003) SARS-CoV clearly warrants further investigation."}

PMC:7271924 / 21279-22358 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7271924 / 21279-22358 JSON TXT