PMC:7271924 / 17202-17767 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7271924","sourcedb":"PMC","sourceid":"7271924","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7271924","text":"Although LF has various means to counteract bacteria as part of its immune function (131), it is also capable of being hijacked to benefit the activities of bacteria. Thus, bacteria can also exploit LF by removing its bound ferric iron (19, 30). This process involves (1) synthesis of high-affinity ferric ion chelators by bacteria, (2) iron acquisition through LF or transferrin binding, mediated by bacterial-specific surface bacterial receptors, (3) or iron acquisition through bacterial reductases, which are able to reduce ferric to ferrous ions (19, 144–148).","tracks":[{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T289","span":{"begin":44,"end":52},"obj":"NCBITaxon:2"},{"id":"T290","span":{"begin":68,"end":74},"obj":"UBERON:0002405"},{"id":"T291","span":{"begin":157,"end":165},"obj":"NCBITaxon:2"},{"id":"T292","span":{"begin":173,"end":181},"obj":"NCBITaxon:2"},{"id":"T293","span":{"begin":224,"end":235},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T294","span":{"begin":299,"end":305},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T295","span":{"begin":306,"end":309},"obj":"CHEBI:24870;CHEBI:24870"},{"id":"T296","span":{"begin":323,"end":331},"obj":"NCBITaxon:2"},{"id":"T297","span":{"begin":368,"end":379},"obj":"PR:000016261"},{"id":"T298","span":{"begin":401,"end":410},"obj":"NCBITaxon:2"},{"id":"T299","span":{"begin":420,"end":427},"obj":"GO:0009986"},{"id":"T300","span":{"begin":428,"end":437},"obj":"NCBITaxon:2"},{"id":"T301","span":{"begin":481,"end":490},"obj":"NCBITaxon:2"},{"id":"T302","span":{"begin":528,"end":534},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T303","span":{"begin":538,"end":545},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T304","span":{"begin":546,"end":550},"obj":"CHEBI:24870;CHEBI:24870"},{"id":"T49535","span":{"begin":44,"end":52},"obj":"NCBITaxon:2"},{"id":"T41509","span":{"begin":68,"end":74},"obj":"UBERON:0002405"},{"id":"T40819","span":{"begin":157,"end":165},"obj":"NCBITaxon:2"},{"id":"T96854","span":{"begin":173,"end":181},"obj":"NCBITaxon:2"},{"id":"T36736","span":{"begin":224,"end":235},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T76602","span":{"begin":299,"end":305},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T34367","span":{"begin":306,"end":309},"obj":"CHEBI:24870;CHEBI:24870"},{"id":"T81272","span":{"begin":323,"end":331},"obj":"NCBITaxon:2"},{"id":"T18157","span":{"begin":368,"end":379},"obj":"PR:000016261"},{"id":"T55060","span":{"begin":401,"end":410},"obj":"NCBITaxon:2"},{"id":"T10880","span":{"begin":420,"end":427},"obj":"GO:0009986"},{"id":"T9261","span":{"begin":428,"end":437},"obj":"NCBITaxon:2"},{"id":"T29742","span":{"begin":481,"end":490},"obj":"NCBITaxon:2"},{"id":"T32833","span":{"begin":528,"end":534},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T15145","span":{"begin":538,"end":545},"obj":"CHEBI:30808;CHEBI:30808"},{"id":"T21053","span":{"begin":546,"end":550},"obj":"CHEBI:24870;CHEBI:24870"}],"attributes":[{"subj":"T289","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T290","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T291","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T292","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T293","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T294","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T295","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T296","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T297","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T298","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T299","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T300","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T301","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T302","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T303","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T304","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T49535","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T41509","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T40819","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T96854","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T36736","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T76602","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T34367","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T81272","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T18157","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T55060","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T10880","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T9261","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T29742","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T32833","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T15145","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T21053","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"395","span":{"begin":368,"end":379},"obj":"Gene"},{"id":"396","span":{"begin":224,"end":235},"obj":"Chemical"},{"id":"397","span":{"begin":299,"end":305},"obj":"Chemical"},{"id":"398","span":{"begin":337,"end":341},"obj":"Chemical"},{"id":"399","span":{"begin":456,"end":460},"obj":"Chemical"},{"id":"400","span":{"begin":528,"end":534},"obj":"Chemical"},{"id":"401","span":{"begin":538,"end":550},"obj":"Chemical"}],"attributes":[{"id":"A395","pred":"tao:has_database_id","subj":"395","obj":"Gene:7018"},{"id":"A398","pred":"tao:has_database_id","subj":"398","obj":"MESH:D007501"},{"id":"A399","pred":"tao:has_database_id","subj":"399","obj":"MESH:D007501"},{"subj":"395","pred":"source","obj":"LitCovid-PubTator"},{"subj":"396","pred":"source","obj":"LitCovid-PubTator"},{"subj":"397","pred":"source","obj":"LitCovid-PubTator"},{"subj":"398","pred":"source","obj":"LitCovid-PubTator"},{"subj":"399","pred":"source","obj":"LitCovid-PubTator"},{"subj":"400","pred":"source","obj":"LitCovid-PubTator"},{"subj":"401","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T227","span":{"begin":12,"end":15},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T228","span":{"begin":44,"end":52},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T229","span":{"begin":143,"end":153},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T230","span":{"begin":157,"end":165},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T231","span":{"begin":173,"end":181},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T232","span":{"begin":323,"end":331},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T233","span":{"begin":560,"end":563},"obj":"http://purl.obolibrary.org/obo/CLO_0001079"}],"attributes":[{"subj":"T227","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T228","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T229","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T230","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T231","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T232","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T233","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T214","span":{"begin":9,"end":11},"obj":"Chemical"},{"id":"T215","span":{"begin":199,"end":201},"obj":"Chemical"},{"id":"T216","span":{"begin":224,"end":235},"obj":"Chemical"},{"id":"T217","span":{"begin":231,"end":235},"obj":"Chemical"},{"id":"T218","span":{"begin":306,"end":309},"obj":"Chemical"},{"id":"T219","span":{"begin":310,"end":319},"obj":"Chemical"},{"id":"T220","span":{"begin":337,"end":341},"obj":"Chemical"},{"id":"T221","span":{"begin":362,"end":364},"obj":"Chemical"},{"id":"T222","span":{"begin":456,"end":460},"obj":"Chemical"},{"id":"T223","span":{"begin":546,"end":550},"obj":"Chemical"}],"attributes":[{"id":"A214","pred":"chebi_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/CHEBI_73585"},{"id":"A215","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_73585"},{"id":"A216","pred":"chebi_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/CHEBI_29034"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_18248"},{"id":"A218","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"id":"A219","pred":"chebi_id","subj":"T219","obj":"http://purl.obolibrary.org/obo/CHEBI_38161"},{"id":"A220","pred":"chebi_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/CHEBI_18248"},{"id":"A221","pred":"chebi_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/CHEBI_73585"},{"id":"A222","pred":"chebi_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/CHEBI_18248"},{"id":"A223","pred":"chebi_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"},{"subj":"T214","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T215","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T218","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T219","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T220","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T221","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T222","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T223","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T39","span":{"begin":272,"end":281},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T40","span":{"begin":337,"end":353},"obj":"http://purl.obolibrary.org/obo/GO_0044847"},{"id":"T41","span":{"begin":456,"end":472},"obj":"http://purl.obolibrary.org/obo/GO_0044847"}],"attributes":[{"subj":"T39","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T141","span":{"begin":0,"end":166},"obj":"Sentence"},{"id":"T142","span":{"begin":167,"end":245},"obj":"Sentence"},{"id":"T143","span":{"begin":246,"end":565},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T141","pred":"source","obj":"LitCovid-sentences"},{"subj":"T142","pred":"source","obj":"LitCovid-sentences"},{"subj":"T143","pred":"source","obj":"LitCovid-sentences"}]},{"project":"MyTest","denotations":[{"id":"32574271-15123561-34514692","span":{"begin":85,"end":88},"obj":"15123561"},{"id":"32574271-28914813-34514693","span":{"begin":237,"end":239},"obj":"28914813"},{"id":"32574271-20711357-34514694","span":{"begin":241,"end":243},"obj":"20711357"},{"id":"32574271-28914813-34514695","span":{"begin":552,"end":554},"obj":"28914813"},{"id":"32574271-28138436-34514696","span":{"begin":556,"end":559},"obj":"28138436"},{"id":"32574271-20155302-34514696","span":{"begin":556,"end":559},"obj":"20155302"},{"id":"32574271-28276700-34514696","span":{"begin":556,"end":559},"obj":"28276700"},{"id":"32574271-10744995-34514696","span":{"begin":556,"end":559},"obj":"10744995"},{"id":"32574271-28426241-34514696","span":{"begin":556,"end":559},"obj":"28426241"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32574271-15123561-34514692","pred":"source","obj":"MyTest"},{"subj":"32574271-28914813-34514693","pred":"source","obj":"MyTest"},{"subj":"32574271-20711357-34514694","pred":"source","obj":"MyTest"},{"subj":"32574271-28914813-34514695","pred":"source","obj":"MyTest"},{"subj":"32574271-28138436-34514696","pred":"source","obj":"MyTest"},{"subj":"32574271-20155302-34514696","pred":"source","obj":"MyTest"},{"subj":"32574271-28276700-34514696","pred":"source","obj":"MyTest"},{"subj":"32574271-10744995-34514696","pred":"source","obj":"MyTest"},{"subj":"32574271-28426241-34514696","pred":"source","obj":"MyTest"}]},{"project":"TEST0","denotations":[{"id":"32574271-85-92-2882284","span":{"begin":85,"end":88},"obj":"[\"15123561\"]"},{"id":"32574271-70-76-2882285","span":{"begin":237,"end":239},"obj":"[\"28914813\"]"},{"id":"32574271-74-80-2882286","span":{"begin":241,"end":243},"obj":"[\"20711357\"]"},{"id":"32574271-232-238-2882287","span":{"begin":552,"end":554},"obj":"[\"28914813\"]"},{"id":"32574271-236-243-2882288","span":{"begin":556,"end":559},"obj":"[\"28138436\", \"20155302\", \"28276700\", \"10744995\", \"28426241\"]"}],"attributes":[{"subj":"32574271-85-92-2882284","pred":"source","obj":"TEST0"},{"subj":"32574271-70-76-2882285","pred":"source","obj":"TEST0"},{"subj":"32574271-74-80-2882286","pred":"source","obj":"TEST0"},{"subj":"32574271-232-238-2882287","pred":"source","obj":"TEST0"},{"subj":"32574271-236-243-2882288","pred":"source","obj":"TEST0"}]},{"project":"2_test","denotations":[{"id":"32574271-15123561-34514692","span":{"begin":85,"end":88},"obj":"15123561"},{"id":"32574271-28914813-34514693","span":{"begin":237,"end":239},"obj":"28914813"},{"id":"32574271-20711357-34514694","span":{"begin":241,"end":243},"obj":"20711357"},{"id":"32574271-28914813-34514695","span":{"begin":552,"end":554},"obj":"28914813"},{"id":"32574271-28138436-34514696","span":{"begin":556,"end":559},"obj":"28138436"},{"id":"32574271-20155302-34514696","span":{"begin":556,"end":559},"obj":"20155302"},{"id":"32574271-28276700-34514696","span":{"begin":556,"end":559},"obj":"28276700"},{"id":"32574271-10744995-34514696","span":{"begin":556,"end":559},"obj":"10744995"},{"id":"32574271-28426241-34514696","span":{"begin":556,"end":559},"obj":"28426241"}],"attributes":[{"subj":"32574271-15123561-34514692","pred":"source","obj":"2_test"},{"subj":"32574271-28914813-34514693","pred":"source","obj":"2_test"},{"subj":"32574271-20711357-34514694","pred":"source","obj":"2_test"},{"subj":"32574271-28914813-34514695","pred":"source","obj":"2_test"},{"subj":"32574271-28138436-34514696","pred":"source","obj":"2_test"},{"subj":"32574271-20155302-34514696","pred":"source","obj":"2_test"},{"subj":"32574271-28276700-34514696","pred":"source","obj":"2_test"},{"subj":"32574271-10744995-34514696","pred":"source","obj":"2_test"},{"subj":"32574271-28426241-34514696","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PMC-OGER-BB","color":"#e8ec93","default":true},{"id":"LitCovid-PubTator","color":"#d593ec"},{"id":"LitCovid-PD-CLO","color":"#93ecbb"},{"id":"LitCovid-PD-CHEBI","color":"#eca193"},{"id":"LitCovid-PD-GO-BP","color":"#939eec"},{"id":"LitCovid-sentences","color":"#b8ec93"},{"id":"MyTest","color":"#ec93d2"},{"id":"TEST0","color":"#93ecec"},{"id":"2_test","color":"#ecd293"}]}]}}