PMC:7271924 / 15609-19166
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T257 | 0-8 | NCBITaxon:2 | denotes | Bacteria |
T258 | 13-24 | PR:000009978 | denotes | Lactoferrin |
T259 | 164-181 | CHEBI:67079;CHEBI:67079 | denotes | anti-inflammatory |
T260 | 192-197 | CHEBI:67079;CHEBI:67079 | denotes | anti- |
T261 | 197-209 | CHEBI:50903;CHEBI:50903 | denotes | carcinogenic |
T262 | 316-324 | NCBITaxon:2 | denotes | Bacteria |
T263 | 366-375 | GO:0051235 | denotes | sequester |
T264 | 407-415 | NCBITaxon:2 | denotes | bacteria |
T265 | 470-481 | PR:000016261 | denotes | transferrin |
T266 | 532-541 | GO:0032991 | denotes | complexes |
T267 | 613-622 | NCBITaxon:2 | denotes | bacterial |
T268 | 623-635 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T269 | 672-683 | PR:000016261 | denotes | transferrin |
T270 | 722-733 | CHEBI:26672;CHEBI:26672 | denotes | siderophore |
T271 | 734-748 | GO:1990391 | denotes | iron complexes |
T272 | 789-798 | NCBITaxon:2 | denotes | bacterium |
T273 | 817-823 | UBERON:0002405 | denotes | immune |
T274 | 903-913 | PR:000009725 | denotes | Neutrophil |
T275 | 914-924 | PR:000009725;CHEBI:5291;CHEBI:5291 | denotes | gelatinase |
T276 | 924-945 | PR:000009725 | denotes | -associated lipocalin |
T277 | 947-951 | PR:000009725 | denotes | NGAL |
T278 | 954-964 | PR:000009725 | denotes | lipocalin2 |
T279 | 968-972 | PR:000009725 | denotes | Lcn2 |
T280 | 988-999 | CHEBI:26672;CHEBI:26672 | denotes | siderophore |
T281 | 1068-1076 | NCBITaxon:2 | denotes | bacteria |
T282 | 1115-1126 | PR:000016261 | denotes | Transferrin |
T283 | 1210-1222 | CHEBI:26672;CHEBI:26672 | denotes | Siderophores |
T284 | 1266-1277 | PR:000016261 | denotes | transferrin |
T285 | 1318-1330 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T286 | 1403-1412 | NCBITaxon:2 | denotes | bacterial |
T287 | 1413-1420 | GO:0006952 | denotes | defense |
T288 | 1476-1488 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T289 | 1637-1645 | NCBITaxon:2 | denotes | bacteria |
T290 | 1661-1667 | UBERON:0002405 | denotes | immune |
T291 | 1750-1758 | NCBITaxon:2 | denotes | bacteria |
T292 | 1766-1774 | NCBITaxon:2 | denotes | bacteria |
T293 | 1817-1828 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T294 | 1892-1898 | CHEBI:30808;CHEBI:30808 | denotes | ferric |
T295 | 1899-1902 | CHEBI:24870;CHEBI:24870 | denotes | ion |
T296 | 1916-1924 | NCBITaxon:2 | denotes | bacteria |
T297 | 1961-1972 | PR:000016261 | denotes | transferrin |
T298 | 1994-2003 | NCBITaxon:2 | denotes | bacterial |
T299 | 2013-2020 | GO:0009986 | denotes | surface |
T300 | 2021-2030 | NCBITaxon:2 | denotes | bacterial |
T301 | 2074-2083 | NCBITaxon:2 | denotes | bacterial |
T302 | 2121-2127 | CHEBI:30808;CHEBI:30808 | denotes | ferric |
T303 | 2131-2138 | CHEBI:30808;CHEBI:30808 | denotes | ferrous |
T304 | 2139-2143 | CHEBI:24870;CHEBI:24870 | denotes | ions |
T305 | 2237-2246 | NCBITaxon:39107 | denotes | Moraxella |
T306 | 2325-2336 | PR:000016261 | denotes | transferrin |
T307 | 2384-2393 | NCBITaxon:2 | denotes | bacterial |
T308 | 2451-2459 | NCBITaxon:2 | denotes | bacteria |
T309 | 2467-2479 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T310 | 2597-2608 | GO:0051235 | denotes | sequestered |
T311 | 2612-2616 | GO:0018995 | denotes | host |
T312 | 2617-2628 | PR:000016261 | denotes | transferrin |
T313 | 2630-2641 | PR:000009978 | denotes | lactoferrin |
T314 | 2690-2698 | GO:0016020 | denotes | membrane |
T315 | 2762-2776 | GO:0019867 | denotes | outer membrane |
T316 | 2778-2782 | PR:000022758 | denotes | TbpA |
T317 | 2787-2798 | PR:000016261 | denotes | transferrin |
T318 | 2812-2823 | PR:000009978 | denotes | lactoferrin |
T319 | 2870-2881 | PR:000009978 | denotes | lactoferrin |
T320 | 2882-2893 | PR:000016261 | denotes | transferrin |
T321 | 2914-2918 | PR:P34123 | denotes | TbpB |
T322 | 2923-2934 | PR:000016261 | denotes | transferrin |
T323 | 2948-2959 | PR:000009978 | denotes | lactoferrin |
T324 | 2993-3004 | PR:000009978 | denotes | lactoferrin |
T325 | 3014-3018 | PR:P34123 | denotes | TbpB |
T326 | 3039-3050 | PR:000016261 | denotes | transferrin |
T327 | 3090-3095 | SP_6;NCBITaxon:9606 | denotes | human |
T328 | 3096-3100 | UBERON:0001913 | denotes | milk |
T329 | 3174-3182 | NCBITaxon:2 | denotes | bacteria |
T330 | 3187-3198 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T331 | 3217-3230 | GO:0008283 | denotes | proliferation |
T332 | 3337-3346 | NCBITaxon:2 | denotes | bacterial |
T333 | 3402-3406 | GO:0006968 | denotes | host |
T334 | 3407-3414 | GO:0006952 | denotes | defense |
T335 | 3514-3520 | GO:0045087 | denotes | innate |
T336 | 3525-3533 | GO:0002250 | denotes | adaptive |
T337 | 3534-3540 | GO:0002250;UBERON:0002405 | denotes | immune |
T338 | 3541-3550 | GO:0002250 | denotes | responses |
T52973 | 0-8 | NCBITaxon:2 | denotes | Bacteria |
T79383 | 13-24 | PR:000009978 | denotes | Lactoferrin |
T28998 | 164-181 | CHEBI:67079;CHEBI:67079 | denotes | anti-inflammatory |
T28206 | 192-197 | CHEBI:67079;CHEBI:67079 | denotes | anti- |
T22567 | 197-209 | CHEBI:50903;CHEBI:50903 | denotes | carcinogenic |
T29752 | 316-324 | NCBITaxon:2 | denotes | Bacteria |
T38268 | 366-375 | GO:0051235 | denotes | sequester |
T95951 | 407-415 | NCBITaxon:2 | denotes | bacteria |
T50235 | 470-481 | PR:000016261 | denotes | transferrin |
T27377 | 532-541 | GO:0032991 | denotes | complexes |
T6187 | 613-622 | NCBITaxon:2 | denotes | bacterial |
T60466 | 623-635 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T26163 | 672-683 | PR:000016261 | denotes | transferrin |
T99376 | 722-733 | CHEBI:26672;CHEBI:26672 | denotes | siderophore |
T75405 | 734-748 | GO:1990391 | denotes | iron complexes |
T43122 | 789-798 | NCBITaxon:2 | denotes | bacterium |
T36286 | 817-823 | UBERON:0002405 | denotes | immune |
T65122 | 903-913 | PR:000009725 | denotes | Neutrophil |
T33617 | 914-924 | PR:000009725;CHEBI:5291;CHEBI:5291 | denotes | gelatinase |
T57091 | 924-945 | PR:000009725 | denotes | -associated lipocalin |
T2273 | 947-951 | PR:000009725 | denotes | NGAL |
T27951 | 954-964 | PR:000009725 | denotes | lipocalin2 |
T31828 | 968-972 | PR:000009725 | denotes | Lcn2 |
T54197 | 988-999 | CHEBI:26672;CHEBI:26672 | denotes | siderophore |
T2557 | 1068-1076 | NCBITaxon:2 | denotes | bacteria |
T45735 | 1115-1126 | PR:000016261 | denotes | Transferrin |
T49430 | 1210-1222 | CHEBI:26672;CHEBI:26672 | denotes | Siderophores |
T62380 | 1266-1277 | PR:000016261 | denotes | transferrin |
T90972 | 1318-1330 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T95320 | 1403-1412 | NCBITaxon:2 | denotes | bacterial |
T45125 | 1413-1420 | GO:0006952 | denotes | defense |
T86561 | 1476-1488 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T49535 | 1637-1645 | NCBITaxon:2 | denotes | bacteria |
T41509 | 1661-1667 | UBERON:0002405 | denotes | immune |
T40819 | 1750-1758 | NCBITaxon:2 | denotes | bacteria |
T96854 | 1766-1774 | NCBITaxon:2 | denotes | bacteria |
T36736 | 1817-1828 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T76602 | 1892-1898 | CHEBI:30808;CHEBI:30808 | denotes | ferric |
T34367 | 1899-1902 | CHEBI:24870;CHEBI:24870 | denotes | ion |
T81272 | 1916-1924 | NCBITaxon:2 | denotes | bacteria |
T18157 | 1961-1972 | PR:000016261 | denotes | transferrin |
T55060 | 1994-2003 | NCBITaxon:2 | denotes | bacterial |
T10880 | 2013-2020 | GO:0009986 | denotes | surface |
T9261 | 2021-2030 | NCBITaxon:2 | denotes | bacterial |
T29742 | 2074-2083 | NCBITaxon:2 | denotes | bacterial |
T32833 | 2121-2127 | CHEBI:30808;CHEBI:30808 | denotes | ferric |
T15145 | 2131-2138 | CHEBI:30808;CHEBI:30808 | denotes | ferrous |
T21053 | 2139-2143 | CHEBI:24870;CHEBI:24870 | denotes | ions |
T26947 | 2237-2246 | NCBITaxon:39107 | denotes | Moraxella |
T65420 | 2325-2336 | PR:000016261 | denotes | transferrin |
T21588 | 2384-2393 | NCBITaxon:2 | denotes | bacterial |
T49891 | 2451-2459 | NCBITaxon:2 | denotes | bacteria |
T30797 | 2467-2479 | CHEBI:26672;CHEBI:26672 | denotes | siderophores |
T12367 | 2597-2608 | GO:0051235 | denotes | sequestered |
T80327 | 2612-2616 | GO:0018995 | denotes | host |
T77009 | 2617-2628 | PR:000016261 | denotes | transferrin |
T40949 | 2630-2641 | PR:000009978 | denotes | lactoferrin |
T66596 | 2690-2698 | GO:0016020 | denotes | membrane |
T73998 | 2762-2776 | GO:0019867 | denotes | outer membrane |
T64162 | 2778-2782 | PR:000022758 | denotes | TbpA |
T34393 | 2787-2798 | PR:000016261 | denotes | transferrin |
T65453 | 2812-2823 | PR:000009978 | denotes | lactoferrin |
T27946 | 2870-2881 | PR:000009978 | denotes | lactoferrin |
T46165 | 2882-2893 | PR:000016261 | denotes | transferrin |
T57015 | 2914-2918 | PR:P34123 | denotes | TbpB |
T55928 | 2923-2934 | PR:000016261 | denotes | transferrin |
T97295 | 2948-2959 | PR:000009978 | denotes | lactoferrin |
T99285 | 2993-3004 | PR:000009978 | denotes | lactoferrin |
T38439 | 3014-3018 | PR:P34123 | denotes | TbpB |
T87300 | 3039-3050 | PR:000016261 | denotes | transferrin |
T90222 | 3090-3095 | SP_6;NCBITaxon:9606 | denotes | human |
T78826 | 3096-3100 | UBERON:0001913 | denotes | milk |
T31225 | 3174-3182 | NCBITaxon:2 | denotes | bacteria |
T47845 | 3187-3198 | CHEBI:30808;CHEBI:30808 | denotes | ferric iron |
T96516 | 3217-3230 | GO:0008283 | denotes | proliferation |
T81850 | 3337-3346 | NCBITaxon:2 | denotes | bacterial |
T70301 | 3402-3406 | GO:0006968 | denotes | host |
T95712 | 3407-3414 | GO:0006952 | denotes | defense |
T65079 | 3514-3520 | GO:0045087 | denotes | innate |
T33909 | 3525-3533 | GO:0002250 | denotes | adaptive |
T42958 | 3534-3540 | GO:0002250;UBERON:0002405 | denotes | immune |
T16651 | 3541-3550 | GO:0002250 | denotes | responses |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
360 | 470-481 | Gene | denotes | transferrin | Gene:7018 |
361 | 483-492 | Gene | denotes | hemopexin | Gene:3263 |
362 | 672-683 | Gene | denotes | transferrin | Gene:7018 |
363 | 685-696 | Gene | denotes | lactoferrin | Gene:280846 |
364 | 903-945 | Gene | denotes | Neutrophil gelatinase-associated lipocalin | Gene:3934 |
365 | 947-951 | Gene | denotes | NGAL | Gene:3934 |
366 | 954-964 | Gene | denotes | lipocalin2 | Gene:3934 |
367 | 968-972 | Gene | denotes | Lcn2 | Gene:3934 |
368 | 520-531 | Gene | denotes | haptoglobin | Gene:3240 |
369 | 241-245 | Chemical | denotes | iron | MESH:D007501 |
370 | 376-380 | Chemical | denotes | iron | MESH:D007501 |
371 | 424-428 | Chemical | denotes | iron | MESH:D007501 |
372 | 647-651 | Chemical | denotes | iron | MESH:D007501 |
373 | 734-738 | Chemical | denotes | iron | MESH:D007501 |
374 | 1009-1013 | Chemical | denotes | iron | MESH:D007501 |
375 | 197-209 | Disease | denotes | carcinogenic | MESH:D063646 |
382 | 1115-1135 | Gene | denotes | Transferrin receptor | Gene:7037 |
383 | 1199-1208 | Gene | denotes | hemopexin | Gene:3263 |
384 | 1240-1251 | Gene | denotes | lactoferrin | Gene:280846 |
385 | 1266-1277 | Gene | denotes | transferrin | Gene:7018 |
386 | 1085-1089 | Chemical | denotes | iron | MESH:D007501 |
387 | 1230-1234 | Chemical | denotes | iron | MESH:D007501 |
395 | 1961-1972 | Gene | denotes | transferrin | Gene:7018 |
396 | 1817-1828 | Chemical | denotes | ferric iron | |
397 | 1892-1898 | Chemical | denotes | ferric | |
398 | 1930-1934 | Chemical | denotes | iron | MESH:D007501 |
399 | 2049-2053 | Chemical | denotes | iron | MESH:D007501 |
400 | 2121-2127 | Chemical | denotes | ferric | |
401 | 2131-2143 | Chemical | denotes | ferrous ions | |
428 | 2325-2336 | Gene | denotes | transferrin | Gene:7018 |
429 | 2617-2628 | Gene | denotes | transferrin | Gene:7018 |
430 | 2630-2641 | Gene | denotes | lactoferrin | Gene:280846 |
431 | 2778-2782 | Gene | denotes | TbpA | Gene:7276 |
432 | 2787-2798 | Gene | denotes | transferrin | Gene:7018 |
433 | 2812-2823 | Gene | denotes | lactoferrin | Gene:280846 |
434 | 2870-2881 | Gene | denotes | lactoferrin | Gene:280846 |
435 | 2882-2893 | Gene | denotes | transferrin | Gene:7018 |
436 | 2923-2934 | Gene | denotes | transferrin | Gene:7018 |
437 | 2948-2959 | Gene | denotes | lactoferrin | Gene:280846 |
438 | 2993-3004 | Gene | denotes | lactoferrin | Gene:280846 |
439 | 3039-3050 | Gene | denotes | transferrin | Gene:7018 |
440 | 2768-2776 | Gene | denotes | membrane | Gene:43740571 |
441 | 2344-2359 | Species | denotes | N. meningitidis | Tax:487 |
442 | 2408-2416 | Species | denotes | children | Tax:9606 |
443 | 3090-3095 | Species | denotes | human | Tax:9606 |
444 | 2690-2698 | Gene | denotes | membrane | Gene:43740571 |
445 | 2299-2303 | Chemical | denotes | iron | MESH:D007501 |
446 | 2504-2508 | Chemical | denotes | iron | MESH:D007501 |
447 | 2592-2596 | Chemical | denotes | iron | MESH:D007501 |
448 | 2746-2750 | Chemical | denotes | iron | MESH:D007501 |
449 | 2858-2862 | Chemical | denotes | iron | MESH:D007501 |
450 | 3187-3198 | Chemical | denotes | ferric iron | |
451 | 2216-2232 | Disease | denotes | genera Neisseria | MESH:D006069 |
452 | 2384-2404 | Disease | denotes | bacterial meningitis | MESH:D016920 |
453 | 2516-2525 | Disease | denotes | Neisseria | MESH:D006069 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T197 | 494-504 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T198 | 509-519 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T199 | 867-874 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T200 | 903-913 | Body_part | denotes | Neutrophil | http://purl.org/sig/ont/fma/fma62860 |
T201 | 2550-2557 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T202 | 2647-2657 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T203 | 2832-2843 | Body_part | denotes | lipoprotein | http://purl.org/sig/ont/fma/fma63169 |
T204 | 3096-3100 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T36 | 2985-2989 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T37 | 3031-3035 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T38 | 3096-3100 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T31 | 2384-2404 | Disease | denotes | bacterial meningitis | http://purl.obolibrary.org/obo/MONDO_0006670 |
T32 | 2394-2404 | Disease | denotes | meningitis | http://purl.obolibrary.org/obo/MONDO_0004796|http://purl.obolibrary.org/obo/MONDO_0021108 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T218 | 0-8 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | Bacteria |
T219 | 111-114 | http://purl.obolibrary.org/obo/CLO_0001079 | denotes | 148 |
T220 | 316-324 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | Bacteria |
T221 | 407-415 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T222 | 520-531 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | haptoglobin |
T223 | 1068-1076 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T224 | 1170-1172 | http://purl.obolibrary.org/obo/UBERON_0000007 | denotes | Hp |
T225 | 1352-1353 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T226 | 1393-1394 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T227 | 1605-1608 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T228 | 1637-1645 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T229 | 1736-1746 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
T230 | 1750-1758 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T231 | 1766-1774 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T232 | 1916-1924 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T233 | 2153-2156 | http://purl.obolibrary.org/obo/CLO_0001079 | denotes | 148 |
T234 | 2363-2364 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T235 | 2451-2459 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T236 | 2526-2529 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T237 | 2538-2539 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T238 | 2688-2689 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T239 | 2690-2698 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T240 | 2768-2776 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T241 | 2830-2831 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T242 | 3090-3095 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T243 | 3174-3182 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T244 | 3377-3378 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T245 | 3499-3500 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T193 | 71-73 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T194 | 117-126 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T195 | 142-152 | Chemical | denotes | antifungal | http://purl.obolibrary.org/obo/CHEBI_35718 |
T196 | 241-245 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T197 | 376-380 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T198 | 424-428 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T199 | 494-504 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T200 | 509-519 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T201 | 551-553 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T202 | 623-635 | Chemical | denotes | siderophores | http://purl.obolibrary.org/obo/CHEBI_26672 |
T203 | 647-651 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T204 | 722-733 | Chemical | denotes | siderophore | http://purl.obolibrary.org/obo/CHEBI_26672 |
T205 | 734-738 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T206 | 867-874 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T207 | 988-999 | Chemical | denotes | siderophore | http://purl.obolibrary.org/obo/CHEBI_26672 |
T208 | 1009-1013 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T209 | 1085-1089 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T210 | 1170-1172 | Chemical | denotes | Hp | http://purl.obolibrary.org/obo/CHEBI_24526 |
T211 | 1230-1234 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T212 | 1318-1330 | Chemical | denotes | siderophores | http://purl.obolibrary.org/obo/CHEBI_26672 |
T213 | 1476-1488 | Chemical | denotes | siderophores | http://purl.obolibrary.org/obo/CHEBI_26672 |
T214 | 1602-1604 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T215 | 1792-1794 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T216 | 1817-1828 | Chemical | denotes | ferric iron | http://purl.obolibrary.org/obo/CHEBI_29034 |
T217 | 1824-1828 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T218 | 1899-1902 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
T219 | 1903-1912 | Chemical | denotes | chelators | http://purl.obolibrary.org/obo/CHEBI_38161 |
T220 | 1930-1934 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T221 | 1955-1957 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T222 | 2049-2053 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T223 | 2139-2143 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
T224 | 2299-2303 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T225 | 2318-2320 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T226 | 2467-2479 | Chemical | denotes | siderophores | http://purl.obolibrary.org/obo/CHEBI_26672 |
T227 | 2504-2508 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T228 | 2550-2557 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T229 | 2592-2596 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T230 | 2647-2657 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T231 | 2746-2750 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T232 | 2832-2843 | Chemical | denotes | lipoprotein | http://purl.obolibrary.org/obo/CHEBI_6495 |
T233 | 2858-2862 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T234 | 3084-3086 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T235 | 3187-3198 | Chemical | denotes | ferric iron | http://purl.obolibrary.org/obo/CHEBI_29034 |
T236 | 3194-3198 | Chemical | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248 |
T237 | 3281-3283 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
T238 | 3358-3360 | Chemical | denotes | LF | http://purl.obolibrary.org/obo/CHEBI_73585 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T37 | 810-823 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune |
T38 | 1009-1025 | http://purl.obolibrary.org/obo/GO_0044847 | denotes | iron acquisition |
T39 | 1865-1874 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T40 | 1930-1946 | http://purl.obolibrary.org/obo/GO_0044847 | denotes | iron acquisition |
T41 | 2049-2065 | http://purl.obolibrary.org/obo/GO_0044847 | denotes | iron acquisition |
T42 | 2550-2570 | http://purl.obolibrary.org/obo/GO_0015031 | denotes | protein transporters |
T43 | 2705-2716 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transporter |
T44 | 2735-2745 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transports |
T45 | 2882-2912 | http://purl.obolibrary.org/obo/GO_0033572 | denotes | transferrin to the transporter |
T46 | 2901-2912 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transporter |
T47 | 3525-3550 | http://purl.obolibrary.org/obo/GO_0002250 | denotes | adaptive immune responses |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T126 | 0-24 | Sentence | denotes | Bacteria and Lactoferrin |
T127 | 25-216 | Sentence | denotes | One of the most well-known characteristics of LF is that it is antibacterial (19, 144–148), antiviral (99, 149–151), antifungal (152–154), anti-inflammatory (26), and anti-carcinogenic (155). |
T128 | 217-315 | Sentence | denotes | Its ability to of limit iron availability to microbes is one of its crucial amicrobial properties. |
T129 | 316-387 | Sentence | denotes | Bacteria have, however, developed various ways to sequester iron (156). |
T130 | 388-559 | Sentence | denotes | Figure 4 shows how bacteria acquire iron through receptor-mediated recognition of transferrin, hemopexin, hemoglobin, or hemoglobin-haptoglobin complexes and also LF (30). |
T131 | 560-715 | Sentence | denotes | As well as binding it directly from the environment, bacterial siderophores can obtain iron by removing it from transferrin, lactoferrin, or ferritin (32). |
T132 | 716-804 | Sentence | denotes | These siderophore-iron complexes are then recognized by receptors on the bacterium (30). |
T133 | 805-1043 | Sentence | denotes | Host innate immune functions are supported by the circulating protein, siderocalin, also known as Neutrophil gelatinase-associated lipocalin (NGAL), lipocalin2 or Lcn2 as it inhibits siderophore-mediated iron acquisition and release (30). |
T134 | 1044-1114 | Sentence | denotes | Figure 4 Ways by which bacteria acquire iron [adapted from (19, 30)]. |
T135 | 1115-1209 | Sentence | denotes | Transferrin receptor, lactoferrin receptor, hemophore (Hp), hemophore receptor, and hemopexin. |
T136 | 1210-1309 | Sentence | denotes | Siderophores remove iron from lactoferrin, ferritin and transferrin, and also from the environment. |
T137 | 1310-1392 | Sentence | denotes | Stealth siderophores are modified in such a way as to prevent siderocalin binding. |
T138 | 1393-1489 | Sentence | denotes | A primary bacterial defense against siderocalin involves the production of stealth siderophores. |
T139 | 1490-1535 | Sentence | denotes | Modified from Rosa et al. and Skaar (19, 30). |
T140 | 1536-1592 | Sentence | denotes | Diagram created with BioRender (https://biorender.com/). |
T141 | 1593-1759 | Sentence | denotes | Although LF has various means to counteract bacteria as part of its immune function (131), it is also capable of being hijacked to benefit the activities of bacteria. |
T142 | 1760-1838 | Sentence | denotes | Thus, bacteria can also exploit LF by removing its bound ferric iron (19, 30). |
T143 | 1839-2158 | Sentence | denotes | This process involves (1) synthesis of high-affinity ferric ion chelators by bacteria, (2) iron acquisition through LF or transferrin binding, mediated by bacterial-specific surface bacterial receptors, (3) or iron acquisition through bacterial reductases, which are able to reduce ferric to ferrous ions (19, 144–148). |
T144 | 2159-2343 | Sentence | denotes | Several Gram-negative pathogens including members of the genera Neisseria and Moraxella have evolved two-component systems that can extract iron from the host LF and transferrin (157). |
T145 | 2344-2417 | Sentence | denotes | N. meningitidis is a principal cause of bacterial meningitis in children. |
T146 | 2418-2664 | Sentence | denotes | While the majority of pathogenic bacteria employ siderophores to chelate and scavenge iron (158), Neisseria has evolved a series of protein transporters that directly hijack iron sequestered in host transferrin, lactoferrin, and hemoglobin (159). |
T147 | 2665-2967 | Sentence | denotes | The system consists of a membrane-bound transporter that extracts and transports iron across the outer membrane (TbpA for transferrin and LbpA for lactoferrin), and a lipoprotein that delivers iron-loaded lactoferrin/transferrin to the transporter (TbpB for transferrin and LbpB for lactoferrin) (157). |
T148 | 2968-3057 | Sentence | denotes | LbpB binds the N-lobe of lactoferrin, whereas TbpB binds the C-lobe of transferrin (157). |
T149 | 3058-3270 | Sentence | denotes | However, more than 90% of LF in human milk is in the form of apolactoferrin (160), which competes with siderophilic bacteria for ferric iron, and disrupts the proliferation of these microbial and other pathogens. |
T150 | 3271-3357 | Sentence | denotes | Similarly LF supplements may play an important role to counteract bacterial processes. |
T151 | 3358-3474 | Sentence | denotes | LF is consequently a significant element of host defense (19), and its levels may vary in health and during disease. |
T152 | 3475-3557 | Sentence | denotes | It is hence known to be a modulator of innate and adaptive immune responses (161). |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T6 | 2394-2404 | Phenotype | denotes | meningitis | http://purl.obolibrary.org/obo/HP_0001287 |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-28914813-34514676 | 103-105 | 28914813 | denotes | 19 |
32574271-28138436-34514677 | 107-110 | 28138436 | denotes | 144 |
32574271-20155302-34514677 | 107-110 | 20155302 | denotes | 144 |
32574271-28276700-34514677 | 107-110 | 28276700 | denotes | 144 |
32574271-10744995-34514677 | 107-110 | 10744995 | denotes | 144 |
32574271-28426241-34514677 | 107-110 | 28426241 | denotes | 144 |
32574271-21887302-34514678 | 128-130 | 21887302 | denotes | 99 |
32574271-25282173-34514679 | 132-135 | 25282173 | denotes | 149 |
32574271-28895925-34514679 | 132-135 | 28895925 | denotes | 149 |
32574271-28699858-34514679 | 132-135 | 28699858 | denotes | 149 |
32574271-28149293-34514680 | 154-157 | 28149293 | denotes | 152 |
32574271-30621597-34514680 | 154-157 | 30621597 | denotes | 152 |
32574271-27139463-34514680 | 154-157 | 27139463 | denotes | 152 |
32574271-30987256-34514681 | 183-185 | 30987256 | denotes | 26 |
32574271-28933602-34514682 | 211-214 | 28933602 | denotes | 155 |
32574271-20964797-34514683 | 382-385 | 20964797 | denotes | 156 |
32574271-20711357-34514684 | 555-557 | 20711357 | denotes | 30 |
32574271-29575574-34514685 | 711-713 | 29575574 | denotes | 32 |
32574271-20711357-34514686 | 800-802 | 20711357 | denotes | 30 |
32574271-20711357-34514687 | 1039-1041 | 20711357 | denotes | 30 |
32574271-28914813-34514688 | 1105-1107 | 28914813 | denotes | 19 |
32574271-20711357-34514689 | 1109-1111 | 20711357 | denotes | 30 |
32574271-28914813-34514690 | 1527-1529 | 28914813 | denotes | 19 |
32574271-20711357-34514691 | 1531-1533 | 20711357 | denotes | 30 |
32574271-15123561-34514692 | 1678-1681 | 15123561 | denotes | 131 |
32574271-28914813-34514693 | 1830-1832 | 28914813 | denotes | 19 |
32574271-20711357-34514694 | 1834-1836 | 20711357 | denotes | 30 |
32574271-28914813-34514695 | 2145-2147 | 28914813 | denotes | 19 |
32574271-28138436-34514696 | 2149-2152 | 28138436 | denotes | 144 |
32574271-20155302-34514696 | 2149-2152 | 20155302 | denotes | 144 |
32574271-28276700-34514696 | 2149-2152 | 28276700 | denotes | 144 |
32574271-10744995-34514696 | 2149-2152 | 10744995 | denotes | 144 |
32574271-28426241-34514696 | 2149-2152 | 28426241 | denotes | 144 |
32574271-25286931-34514697 | 2338-2341 | 25286931 | denotes | 157 |
32574271-18675317-34514698 | 2510-2513 | 18675317 | denotes | 158 |
32574271-10383753-34514699 | 2659-2662 | 10383753 | denotes | 159 |
32574271-25286931-34514700 | 2962-2965 | 25286931 | denotes | 157 |
32574271-25286931-34514701 | 3052-3055 | 25286931 | denotes | 157 |
32574271-7359228-34514702 | 3135-3138 | 7359228 | denotes | 160 |
32574271-28914813-34514703 | 3416-3418 | 28914813 | denotes | 19 |
32574271-27234406-34514704 | 3552-3555 | 27234406 | denotes | 161 |
TEST0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-78-84-2882268 | 103-105 | ["28914813"] | denotes | 19 |
32574271-82-89-2882269 | 107-110 | ["28138436", "20155302", "28276700", "10744995", "28426241"] | denotes | 144 |
32574271-103-109-2882270 | 128-130 | ["21887302"] | denotes | 99 |
32574271-107-114-2882271 | 132-135 | ["25282173", "28895925", "28699858"] | denotes | 149 |
32574271-129-136-2882272 | 154-157 | ["28149293", "30621597", "27139463"] | denotes | 152 |
32574271-158-164-2882273 | 183-185 | ["30987256"] | denotes | 26 |
32574271-186-193-2882274 | 211-214 | ["28933602"] | denotes | 155 |
32574271-66-73-2882275 | 382-385 | ["20964797"] | denotes | 156 |
32574271-167-173-2882276 | 555-557 | ["20711357"] | denotes | 30 |
32574271-151-157-2882277 | 711-713 | ["29575574"] | denotes | 32 |
32574271-84-90-2882278 | 800-802 | ["20711357"] | denotes | 30 |
32574271-234-240-2882279 | 1039-1041 | ["20711357"] | denotes | 30 |
32574271-51-57-2882280 | 1105-1107 | ["28914813"] | denotes | 19 |
32574271-55-61-2882281 | 1109-1111 | ["20711357"] | denotes | 30 |
32574271-37-43-2882282 | 1527-1529 | ["28914813"] | denotes | 19 |
32574271-41-47-2882283 | 1531-1533 | ["20711357"] | denotes | 30 |
32574271-85-92-2882284 | 1678-1681 | ["15123561"] | denotes | 131 |
32574271-70-76-2882285 | 1830-1832 | ["28914813"] | denotes | 19 |
32574271-74-80-2882286 | 1834-1836 | ["20711357"] | denotes | 30 |
32574271-232-238-2882287 | 2145-2147 | ["28914813"] | denotes | 19 |
32574271-236-243-2882288 | 2149-2152 | ["28138436", "20155302", "28276700", "10744995", "28426241"] | denotes | 144 |
32574271-179-186-2882289 | 2338-2341 | ["25286931"] | denotes | 157 |
32574271-92-99-2882290 | 2510-2513 | ["18675317"] | denotes | 158 |
32574271-235-242-2882291 | 2659-2662 | ["10383753"] | denotes | 159 |
32574271-231-238-2882292 | 2962-2965 | ["25286931"] | denotes | 157 |
32574271-84-91-2882293 | 3052-3055 | ["25286931"] | denotes | 157 |
32574271-77-84-2882294 | 3135-3138 | ["7359228"] | denotes | 160 |
32574271-58-64-2882295 | 3416-3418 | ["28914813"] | denotes | 19 |
32574271-77-84-2882296 | 3552-3555 | ["27234406"] | denotes | 161 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574271-28914813-34514676 | 103-105 | 28914813 | denotes | 19 |
32574271-28138436-34514677 | 107-110 | 28138436 | denotes | 144 |
32574271-20155302-34514677 | 107-110 | 20155302 | denotes | 144 |
32574271-28276700-34514677 | 107-110 | 28276700 | denotes | 144 |
32574271-10744995-34514677 | 107-110 | 10744995 | denotes | 144 |
32574271-28426241-34514677 | 107-110 | 28426241 | denotes | 144 |
32574271-21887302-34514678 | 128-130 | 21887302 | denotes | 99 |
32574271-25282173-34514679 | 132-135 | 25282173 | denotes | 149 |
32574271-28895925-34514679 | 132-135 | 28895925 | denotes | 149 |
32574271-28699858-34514679 | 132-135 | 28699858 | denotes | 149 |
32574271-28149293-34514680 | 154-157 | 28149293 | denotes | 152 |
32574271-30621597-34514680 | 154-157 | 30621597 | denotes | 152 |
32574271-27139463-34514680 | 154-157 | 27139463 | denotes | 152 |
32574271-30987256-34514681 | 183-185 | 30987256 | denotes | 26 |
32574271-28933602-34514682 | 211-214 | 28933602 | denotes | 155 |
32574271-20964797-34514683 | 382-385 | 20964797 | denotes | 156 |
32574271-20711357-34514684 | 555-557 | 20711357 | denotes | 30 |
32574271-29575574-34514685 | 711-713 | 29575574 | denotes | 32 |
32574271-20711357-34514686 | 800-802 | 20711357 | denotes | 30 |
32574271-20711357-34514687 | 1039-1041 | 20711357 | denotes | 30 |
32574271-28914813-34514688 | 1105-1107 | 28914813 | denotes | 19 |
32574271-20711357-34514689 | 1109-1111 | 20711357 | denotes | 30 |
32574271-28914813-34514690 | 1527-1529 | 28914813 | denotes | 19 |
32574271-20711357-34514691 | 1531-1533 | 20711357 | denotes | 30 |
32574271-15123561-34514692 | 1678-1681 | 15123561 | denotes | 131 |
32574271-28914813-34514693 | 1830-1832 | 28914813 | denotes | 19 |
32574271-20711357-34514694 | 1834-1836 | 20711357 | denotes | 30 |
32574271-28914813-34514695 | 2145-2147 | 28914813 | denotes | 19 |
32574271-28138436-34514696 | 2149-2152 | 28138436 | denotes | 144 |
32574271-20155302-34514696 | 2149-2152 | 20155302 | denotes | 144 |
32574271-28276700-34514696 | 2149-2152 | 28276700 | denotes | 144 |
32574271-10744995-34514696 | 2149-2152 | 10744995 | denotes | 144 |
32574271-28426241-34514696 | 2149-2152 | 28426241 | denotes | 144 |
32574271-25286931-34514697 | 2338-2341 | 25286931 | denotes | 157 |
32574271-18675317-34514698 | 2510-2513 | 18675317 | denotes | 158 |
32574271-10383753-34514699 | 2659-2662 | 10383753 | denotes | 159 |
32574271-25286931-34514700 | 2962-2965 | 25286931 | denotes | 157 |
32574271-25286931-34514701 | 3052-3055 | 25286931 | denotes | 157 |
32574271-7359228-34514702 | 3135-3138 | 7359228 | denotes | 160 |
32574271-28914813-34514703 | 3416-3418 | 28914813 | denotes | 19 |
32574271-27234406-34514704 | 3552-3555 | 27234406 | denotes | 161 |