PMC:7271924 / 10081-11574 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"243","span":{"begin":324,"end":336},"obj":"Gene"},{"id":"269","span":{"begin":13,"end":24},"obj":"Gene"},{"id":"270","span":{"begin":108,"end":113},"obj":"Gene"},{"id":"271","span":{"begin":1032,"end":1044},"obj":"Gene"},{"id":"1485","span":{"begin":679,"end":694},"obj":"Chemical"}],"attributes":[{"id":"A243","pred":"tao:has_database_id","subj":"243","obj":"Gene:55600"},{"id":"A269","pred":"tao:has_database_id","subj":"269","obj":"Gene:280846"},{"id":"A270","pred":"tao:has_database_id","subj":"270","obj":"Gene:4035"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"Gene:55600"},{"id":"A1485","pred":"tao:has_database_id","subj":"1485","obj":"MESH:D006497"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T92","span":{"begin":27,"end":31},"obj":"Body_part"},{"id":"T93","span":{"begin":180,"end":187},"obj":"Body_part"},{"id":"T94","span":{"begin":192,"end":196},"obj":"Body_part"},{"id":"T95","span":{"begin":213,"end":223},"obj":"Body_part"},{"id":"T96","span":{"begin":224,"end":239},"obj":"Body_part"},{"id":"T97","span":{"begin":235,"end":239},"obj":"Body_part"},{"id":"T98","span":{"begin":240,"end":251},"obj":"Body_part"},{"id":"T99","span":{"begin":253,"end":264},"obj":"Body_part"},{"id":"T100","span":{"begin":266,"end":273},"obj":"Body_part"},{"id":"T101","span":{"begin":275,"end":286},"obj":"Body_part"},{"id":"T102","span":{"begin":288,"end":305},"obj":"Body_part"},{"id":"T103","span":{"begin":300,"end":305},"obj":"Body_part"},{"id":"T104","span":{"begin":389,"end":406},"obj":"Body_part"},{"id":"T105","span":{"begin":401,"end":406},"obj":"Body_part"},{"id":"T106","span":{"begin":417,"end":422},"obj":"Body_part"},{"id":"T107","span":{"begin":431,"end":460},"obj":"Body_part"},{"id":"T108","span":{"begin":438,"end":443},"obj":"Body_part"},{"id":"T109","span":{"begin":445,"end":460},"obj":"Body_part"},{"id":"T110","span":{"begin":462,"end":467},"obj":"Body_part"},{"id":"T111","span":{"begin":469,"end":474},"obj":"Body_part"},{"id":"T112","span":{"begin":480,"end":486},"obj":"Body_part"},{"id":"T113","span":{"begin":512,"end":529},"obj":"Body_part"},{"id":"T114","span":{"begin":524,"end":529},"obj":"Body_part"},{"id":"T115","span":{"begin":531,"end":540},"obj":"Body_part"},{"id":"T116","span":{"begin":542,"end":553},"obj":"Body_part"},{"id":"T117","span":{"begin":570,"end":579},"obj":"Body_part"},{"id":"T118","span":{"begin":581,"end":598},"obj":"Body_part"},{"id":"T119","span":{"begin":593,"end":598},"obj":"Body_part"},{"id":"T120","span":{"begin":600,"end":611},"obj":"Body_part"},{"id":"T121","span":{"begin":615,"end":620},"obj":"Body_part"},{"id":"T122","span":{"begin":640,"end":651},"obj":"Body_part"},{"id":"T123","span":{"begin":653,"end":664},"obj":"Body_part"},{"id":"T124","span":{"begin":679,"end":708},"obj":"Body_part"},{"id":"T125","span":{"begin":679,"end":694},"obj":"Body_part"},{"id":"T126","span":{"begin":679,"end":686},"obj":"Body_part"},{"id":"T127","span":{"begin":710,"end":715},"obj":"Body_part"},{"id":"T128","span":{"begin":719,"end":735},"obj":"Body_part"},{"id":"T129","span":{"begin":730,"end":735},"obj":"Body_part"},{"id":"T130","span":{"begin":737,"end":754},"obj":"Body_part"},{"id":"T131","span":{"begin":749,"end":754},"obj":"Body_part"},{"id":"T132","span":{"begin":756,"end":767},"obj":"Body_part"},{"id":"T133","span":{"begin":769,"end":780},"obj":"Body_part"},{"id":"T134","span":{"begin":791,"end":804},"obj":"Body_part"},{"id":"T135","span":{"begin":791,"end":802},"obj":"Body_part"},{"id":"T136","span":{"begin":814,"end":819},"obj":"Body_part"},{"id":"T137","span":{"begin":1068,"end":1074},"obj":"Body_part"},{"id":"T138","span":{"begin":1251,"end":1270},"obj":"Body_part"},{"id":"T139","span":{"begin":1332,"end":1335},"obj":"Body_part"},{"id":"T140","span":{"begin":1393,"end":1422},"obj":"Body_part"},{"id":"T141","span":{"begin":1393,"end":1408},"obj":"Body_part"},{"id":"T142","span":{"begin":1393,"end":1400},"obj":"Body_part"},{"id":"T143","span":{"begin":1424,"end":1429},"obj":"Body_part"},{"id":"T144","span":{"begin":1459,"end":1462},"obj":"Body_part"}],"attributes":[{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma54527"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma14515"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma66773"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A106","pred":"fma_id","subj":"T106","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A107","pred":"fma_id","subj":"T107","obj":"http://purl.org/sig/ont/fma/fma86929"},{"id":"A108","pred":"fma_id","subj":"T108","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A109","pred":"fma_id","subj":"T109","obj":"http://purl.org/sig/ont/fma/fma7200"},{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma14543"},{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma7209"},{"id":"A112","pred":"fma_id","subj":"T112","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A113","pred":"fma_id","subj":"T113","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A114","pred":"fma_id","subj":"T114","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A115","pred":"fma_id","subj":"T115","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A116","pred":"fma_id","subj":"T116","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A117","pred":"fma_id","subj":"T117","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A118","pred":"fma_id","subj":"T118","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A119","pred":"fma_id","subj":"T119","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A120","pred":"fma_id","subj":"T120","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A121","pred":"fma_id","subj":"T121","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A122","pred":"fma_id","subj":"T122","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A123","pred":"fma_id","subj":"T123","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A124","pred":"fma_id","subj":"T124","obj":"http://purl.org/sig/ont/fma/fma82834"},{"id":"A125","pred":"fma_id","subj":"T125","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A126","pred":"fma_id","subj":"T126","obj":"http://purl.org/sig/ont/fma/fma67110"},{"id":"A127","pred":"fma_id","subj":"T127","obj":"http://purl.org/sig/ont/fma/fma82834"},{"id":"A128","pred":"fma_id","subj":"T128","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A129","pred":"fma_id","subj":"T129","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A130","pred":"fma_id","subj":"T130","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A131","pred":"fma_id","subj":"T131","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A132","pred":"fma_id","subj":"T132","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A133","pred":"fma_id","subj":"T133","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A134","pred":"fma_id","subj":"T134","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A135","pred":"fma_id","subj":"T135","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A136","pred":"fma_id","subj":"T136","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A137","pred":"fma_id","subj":"T137","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A138","pred":"fma_id","subj":"T138","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A139","pred":"fma_id","subj":"T139","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A140","pred":"fma_id","subj":"T140","obj":"http://purl.org/sig/ont/fma/fma82834"},{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma67110"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma82834"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":445,"end":460},"obj":"Body_part"},{"id":"T28","span":{"begin":451,"end":460},"obj":"Body_part"},{"id":"T29","span":{"begin":462,"end":467},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T21","span":{"begin":1001,"end":1008},"obj":"Disease"},{"id":"T22","span":{"begin":1367,"end":1376},"obj":"Disease"},{"id":"T23","span":{"begin":1467,"end":1475},"obj":"Disease"}],"attributes":[{"id":"A21","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"},{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T118","span":{"begin":27,"end":37},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T119","span":{"begin":192,"end":202},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T120","span":{"begin":213,"end":223},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"T121","span":{"begin":213,"end":223},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T122","span":{"begin":224,"end":234},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T123","span":{"begin":235,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T124","span":{"begin":253,"end":264},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T125","span":{"begin":288,"end":305},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T126","span":{"begin":320,"end":322},"obj":"http://purl.obolibrary.org/obo/CLO_0054055"},{"id":"T127","span":{"begin":384,"end":387},"obj":"http://purl.obolibrary.org/obo/UBERON_0001013"},{"id":"T128","span":{"begin":389,"end":406},"obj":"http://purl.obolibrary.org/obo/CL_0000077"},{"id":"T129","span":{"begin":417,"end":422},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T130","span":{"begin":424,"end":430},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T131","span":{"begin":438,"end":443},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T132","span":{"begin":445,"end":460},"obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"T133","span":{"begin":462,"end":467},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T134","span":{"begin":469,"end":474},"obj":"http://www.ebi.ac.uk/efo/EFO_0000973"},{"id":"T135","span":{"begin":480,"end":486},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T136","span":{"begin":497,"end":501},"obj":"http://purl.obolibrary.org/obo/CLO_0050768"},{"id":"T137","span":{"begin":512,"end":529},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T138","span":{"begin":581,"end":598},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T139","span":{"begin":613,"end":620},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T140","span":{"begin":679,"end":708},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T141","span":{"begin":710,"end":715},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T142","span":{"begin":719,"end":729},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T143","span":{"begin":730,"end":735},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T144","span":{"begin":737,"end":754},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T145","span":{"begin":756,"end":767},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T146","span":{"begin":791,"end":804},"obj":"http://purl.obolibrary.org/obo/PR_000001091"},{"id":"T147","span":{"begin":814,"end":819},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T148","span":{"begin":979,"end":987},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T149","span":{"begin":1015,"end":1016},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T150","span":{"begin":1302,"end":1304},"obj":"http://purl.obolibrary.org/obo/CLO_0001527"},{"id":"T151","span":{"begin":1313,"end":1320},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T152","span":{"begin":1377,"end":1382},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T153","span":{"begin":1393,"end":1422},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T154","span":{"begin":1424,"end":1429},"obj":"http://purl.obolibrary.org/obo/PR_000001307"},{"id":"T155","span":{"begin":1440,"end":1447},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T156","span":{"begin":1489,"end":1492},"obj":"http://purl.obolibrary.org/obo/CLO_0054060"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T128","span":{"begin":679,"end":694},"obj":"Chemical"},{"id":"T129","span":{"begin":687,"end":694},"obj":"Chemical"},{"id":"T130","span":{"begin":695,"end":708},"obj":"Chemical"},{"id":"T131","span":{"begin":829,"end":838},"obj":"Chemical"},{"id":"T132","span":{"begin":1009,"end":1013},"obj":"Chemical"},{"id":"T133","span":{"begin":1088,"end":1105},"obj":"Chemical"},{"id":"T134","span":{"begin":1116,"end":1138},"obj":"Chemical"},{"id":"T135","span":{"begin":1118,"end":1138},"obj":"Chemical"},{"id":"T137","span":{"begin":1118,"end":1126},"obj":"Chemical"},{"id":"T138","span":{"begin":1129,"end":1138},"obj":"Chemical"},{"id":"T142","span":{"begin":1172,"end":1176},"obj":"Chemical"},{"id":"T143","span":{"begin":1218,"end":1222},"obj":"Chemical"},{"id":"T144","span":{"begin":1224,"end":1227},"obj":"Chemical"},{"id":"T145","span":{"begin":1251,"end":1270},"obj":"Chemical"},{"id":"T146","span":{"begin":1272,"end":1276},"obj":"Chemical"},{"id":"T147","span":{"begin":1357,"end":1360},"obj":"Chemical"},{"id":"T150","span":{"begin":1393,"end":1408},"obj":"Chemical"},{"id":"T151","span":{"begin":1401,"end":1408},"obj":"Chemical"},{"id":"T152","span":{"begin":1409,"end":1422},"obj":"Chemical"}],"attributes":[{"id":"A128","pred":"chebi_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/CHEBI_28815"},{"id":"A129","pred":"chebi_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A130","pred":"chebi_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/CHEBI_37396"},{"id":"A131","pred":"chebi_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A132","pred":"chebi_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A133","pred":"chebi_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/CHEBI_143624"},{"id":"A134","pred":"chebi_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/CHEBI_15978"},{"id":"A135","pred":"chebi_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/CHEBI_14336"},{"id":"A136","pred":"chebi_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/CHEBI_231935"},{"id":"A137","pred":"chebi_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/CHEBI_17754"},{"id":"A138","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_18367"},{"id":"A139","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_26020"},{"id":"A140","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_35780"},{"id":"A141","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_43474"},{"id":"A142","pred":"chebi_id","subj":"T142","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A143","pred":"chebi_id","subj":"T143","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A144","pred":"chebi_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/CHEBI_32817"},{"id":"A145","pred":"chebi_id","subj":"T145","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A146","pred":"chebi_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A147","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A148","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A149","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A150","pred":"chebi_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/CHEBI_28815"},{"id":"A151","pred":"chebi_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A152","pred":"chebi_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/CHEBI_37396"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T18","span":{"begin":563,"end":568},"obj":"http://purl.obolibrary.org/obo/GO_0038147"},{"id":"T19","span":{"begin":1306,"end":1311},"obj":"http://purl.obolibrary.org/obo/GO_0038147"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T77","span":{"begin":0,"end":86},"obj":"Sentence"},{"id":"T78","span":{"begin":87,"end":323},"obj":"Sentence"},{"id":"T79","span":{"begin":324,"end":496},"obj":"Sentence"},{"id":"T80","span":{"begin":497,"end":562},"obj":"Sentence"},{"id":"T81","span":{"begin":563,"end":633},"obj":"Sentence"},{"id":"T82","span":{"begin":634,"end":678},"obj":"Sentence"},{"id":"T83","span":{"begin":679,"end":790},"obj":"Sentence"},{"id":"T84","span":{"begin":791,"end":819},"obj":"Sentence"},{"id":"T85","span":{"begin":820,"end":904},"obj":"Sentence"},{"id":"T86","span":{"begin":905,"end":956},"obj":"Sentence"},{"id":"T87","span":{"begin":957,"end":993},"obj":"Sentence"},{"id":"T88","span":{"begin":994,"end":1031},"obj":"Sentence"},{"id":"T89","span":{"begin":1032,"end":1234},"obj":"Sentence"},{"id":"T90","span":{"begin":1235,"end":1305},"obj":"Sentence"},{"id":"T91","span":{"begin":1306,"end":1350},"obj":"Sentence"},{"id":"T92","span":{"begin":1351,"end":1392},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    LitCovid-PD-GlycoEpitope

    {"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T4","span":{"begin":679,"end":694},"obj":"GlycoEpitope"},{"id":"T5","span":{"begin":1393,"end":1408},"obj":"GlycoEpitope"}],"attributes":[{"id":"A4","pred":"glyco_epitope_db_id","subj":"T4","obj":"http://www.glycoepitope.jp/epitopes/EP0086"},{"id":"A5","pred":"glyco_epitope_db_id","subj":"T5","obj":"http://www.glycoepitope.jp/epitopes/EP0086"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    MyTest

    {"project":"MyTest","denotations":[{"id":"32574271-22292499-34514609","span":{"begin":308,"end":310},"obj":"22292499"},{"id":"32574271-21935933-34514610","span":{"begin":313,"end":315},"obj":"21935933"},{"id":"32574271-28669880-34514611","span":{"begin":317,"end":319},"obj":"28669880"},{"id":"32574271-17609417-34514611","span":{"begin":317,"end":319},"obj":"17609417"},{"id":"32574271-18830615-34514611","span":{"begin":317,"end":319},"obj":"18830615"},{"id":"32574271-18670097-34514612","span":{"begin":489,"end":491},"obj":"18670097"},{"id":"32574271-28640441-34514613","span":{"begin":493,"end":495},"obj":"28640441"},{"id":"32574271-28489816-34514614","span":{"begin":556,"end":558},"obj":"28489816"},{"id":"32574271-29383704-34514614","span":{"begin":556,"end":558},"obj":"29383704"},{"id":"32574271-30824879-34514614","span":{"begin":556,"end":558},"obj":"30824879"},{"id":"32574271-31196615-34514614","span":{"begin":556,"end":558},"obj":"31196615"},{"id":"32574271-31451099-34514614","span":{"begin":556,"end":558},"obj":"31451099"},{"id":"32574271-32279287-34514614","span":{"begin":556,"end":558},"obj":"32279287"},{"id":"32574271-22608210-34514614","span":{"begin":556,"end":558},"obj":"22608210"},{"id":"32574271-26773018-34514614","span":{"begin":556,"end":558},"obj":"26773018"},{"id":"32574271-32279287-34514615","span":{"begin":623,"end":625},"obj":"32279287"},{"id":"32574271-19494325-34514616","span":{"begin":627,"end":629},"obj":"19494325"},{"id":"32574271-29734477-34514616","span":{"begin":627,"end":629},"obj":"29734477"},{"id":"32574271-30940657-34514616","span":{"begin":627,"end":629},"obj":"30940657"},{"id":"32574271-22292499-34514617","span":{"begin":667,"end":669},"obj":"22292499"},{"id":"32574271-27911102-34514618","span":{"begin":671,"end":673},"obj":"27911102"},{"id":"32574271-30529429-34514619","span":{"begin":675,"end":677},"obj":"30529429"},{"id":"32574271-21690215-34514620","span":{"begin":783,"end":785},"obj":"21690215"},{"id":"32574271-25187545-34514621","span":{"begin":787,"end":789},"obj":"25187545"},{"id":"32574271-20711357-34514622","span":{"begin":990,"end":992},"obj":"20711357"},{"id":"32574271-28669880-34514623","span":{"begin":1021,"end":1023},"obj":"28669880"},{"id":"32574271-26807022-34514624","span":{"begin":1025,"end":1027},"obj":"26807022"},{"id":"32574271-17920016-34514624","span":{"begin":1025,"end":1027},"obj":"17920016"},{"id":"32574271-24305823-34514624","span":{"begin":1025,"end":1027},"obj":"24305823"},{"id":"32574271-31930911-34514625","span":{"begin":1231,"end":1233},"obj":"31930911"},{"id":"32574271-32279287-34514626","span":{"begin":1295,"end":1297},"obj":"32279287"},{"id":"32574271-26345428-34514627","span":{"begin":1299,"end":1301},"obj":"26345428"},{"id":"32574271-30791839-34514627","span":{"begin":1299,"end":1301},"obj":"30791839"},{"id":"32574271-30419930-34514627","span":{"begin":1299,"end":1301},"obj":"30419930"},{"id":"32574271-32279287-34514628","span":{"begin":1339,"end":1341},"obj":"32279287"},{"id":"32574271-31262533-34514629","span":{"begin":1343,"end":1345},"obj":"31262533"},{"id":"32574271-30966844-34514630","span":{"begin":1347,"end":1349},"obj":"30966844"},{"id":"32574271-26345428-34514631","span":{"begin":1385,"end":1387},"obj":"26345428"},{"id":"32574271-31165725-34514632","span":{"begin":1389,"end":1391},"obj":"31165725"},{"id":"32574271-21690215-34514633","span":{"begin":1478,"end":1480},"obj":"21690215"},{"id":"32574271-25187545-34514634","span":{"begin":1482,"end":1484},"obj":"25187545"},{"id":"32574271-2849510-34514635","span":{"begin":1486,"end":1488},"obj":"2849510"},{"id":"32574271-21887302-34514635","span":{"begin":1486,"end":1488},"obj":"21887302"},{"id":"32574271-31315999-34514635","span":{"begin":1486,"end":1488},"obj":"31315999"},{"id":"32574271-31266258-34514635","span":{"begin":1486,"end":1488},"obj":"31266258"},{"id":"32574271-30959796-34514635","span":{"begin":1486,"end":1488},"obj":"30959796"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    TEST0

    {"project":"TEST0","denotations":[{"id":"32574271-227-233-2882201","span":{"begin":308,"end":310},"obj":"[\"22292499\"]"},{"id":"32574271-232-238-2882202","span":{"begin":313,"end":315},"obj":"[\"21935933\"]"},{"id":"32574271-236-242-2882203","span":{"begin":317,"end":319},"obj":"[\"28669880\", \"17609417\", \"18830615\"]"},{"id":"32574271-229-235-2882204","span":{"begin":489,"end":491},"obj":"[\"18670097\"]"},{"id":"32574271-233-239-2882205","span":{"begin":493,"end":495},"obj":"[\"28640441\"]"},{"id":"32574271-234-240-2882206","span":{"begin":556,"end":558},"obj":"[\"28489816\", \"29383704\", \"30824879\", \"31196615\", \"31451099\", \"32279287\", \"22608210\", \"26773018\"]"},{"id":"32574271-227-233-2882207","span":{"begin":623,"end":625},"obj":"[\"32279287\"]"},{"id":"32574271-231-237-2882208","span":{"begin":627,"end":629},"obj":"[\"19494325\", \"29734477\", \"30940657\"]"},{"id":"32574271-233-239-2882209","span":{"begin":667,"end":669},"obj":"[\"22292499\"]"},{"id":"32574271-237-243-2882210","span":{"begin":671,"end":673},"obj":"[\"27911102\"]"},{"id":"32574271-234-240-2882211","span":{"begin":675,"end":677},"obj":"[\"30529429\"]"},{"id":"32574271-235-241-2882212","span":{"begin":783,"end":785},"obj":"[\"21690215\"]"},{"id":"32574271-228-234-2882213","span":{"begin":787,"end":789},"obj":"[\"25187545\"]"},{"id":"32574271-235-241-2882214","span":{"begin":990,"end":992},"obj":"[\"20711357\"]"},{"id":"32574271-229-235-2882215","span":{"begin":1021,"end":1023},"obj":"[\"28669880\"]"},{"id":"32574271-233-239-2882216","span":{"begin":1025,"end":1027},"obj":"[\"26807022\", \"17920016\", \"24305823\"]"},{"id":"32574271-215-221-2882217","span":{"begin":1231,"end":1233},"obj":"[\"31930911\"]"},{"id":"32574271-220-226-2882218","span":{"begin":1295,"end":1297},"obj":"[\"32279287\"]"},{"id":"32574271-224-230-2882219","span":{"begin":1299,"end":1301},"obj":"[\"26345428\", \"30791839\", \"30419930\"]"},{"id":"32574271-221-227-2882220","span":{"begin":1339,"end":1341},"obj":"[\"32279287\"]"},{"id":"32574271-225-231-2882221","span":{"begin":1343,"end":1345},"obj":"[\"31262533\"]"},{"id":"32574271-229-235-2882222","span":{"begin":1347,"end":1349},"obj":"[\"30966844\"]"},{"id":"32574271-228-234-2882223","span":{"begin":1385,"end":1387},"obj":"[\"26345428\"]"},{"id":"32574271-232-238-2882224","span":{"begin":1389,"end":1391},"obj":"[\"31165725\"]"},{"id":"32574271-233-239-2882225","span":{"begin":1478,"end":1480},"obj":"[\"21690215\"]"},{"id":"32574271-237-243-2882226","span":{"begin":1482,"end":1484},"obj":"[\"25187545\"]"},{"id":"32574271-218-224-2882227","span":{"begin":1486,"end":1488},"obj":"[\"2849510\", \"21887302\", \"31315999\", \"31266258\", \"30959796\"]"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}

    2_test

    {"project":"2_test","denotations":[{"id":"32574271-22292499-34514609","span":{"begin":308,"end":310},"obj":"22292499"},{"id":"32574271-21935933-34514610","span":{"begin":313,"end":315},"obj":"21935933"},{"id":"32574271-28669880-34514611","span":{"begin":317,"end":319},"obj":"28669880"},{"id":"32574271-17609417-34514611","span":{"begin":317,"end":319},"obj":"17609417"},{"id":"32574271-18830615-34514611","span":{"begin":317,"end":319},"obj":"18830615"},{"id":"32574271-18670097-34514612","span":{"begin":489,"end":491},"obj":"18670097"},{"id":"32574271-28640441-34514613","span":{"begin":493,"end":495},"obj":"28640441"},{"id":"32574271-28489816-34514614","span":{"begin":556,"end":558},"obj":"28489816"},{"id":"32574271-29383704-34514614","span":{"begin":556,"end":558},"obj":"29383704"},{"id":"32574271-30824879-34514614","span":{"begin":556,"end":558},"obj":"30824879"},{"id":"32574271-31196615-34514614","span":{"begin":556,"end":558},"obj":"31196615"},{"id":"32574271-31451099-34514614","span":{"begin":556,"end":558},"obj":"31451099"},{"id":"32574271-32279287-34514614","span":{"begin":556,"end":558},"obj":"32279287"},{"id":"32574271-22608210-34514614","span":{"begin":556,"end":558},"obj":"22608210"},{"id":"32574271-26773018-34514614","span":{"begin":556,"end":558},"obj":"26773018"},{"id":"32574271-32279287-34514615","span":{"begin":623,"end":625},"obj":"32279287"},{"id":"32574271-19494325-34514616","span":{"begin":627,"end":629},"obj":"19494325"},{"id":"32574271-29734477-34514616","span":{"begin":627,"end":629},"obj":"29734477"},{"id":"32574271-30940657-34514616","span":{"begin":627,"end":629},"obj":"30940657"},{"id":"32574271-22292499-34514617","span":{"begin":667,"end":669},"obj":"22292499"},{"id":"32574271-27911102-34514618","span":{"begin":671,"end":673},"obj":"27911102"},{"id":"32574271-30529429-34514619","span":{"begin":675,"end":677},"obj":"30529429"},{"id":"32574271-21690215-34514620","span":{"begin":783,"end":785},"obj":"21690215"},{"id":"32574271-25187545-34514621","span":{"begin":787,"end":789},"obj":"25187545"},{"id":"32574271-20711357-34514622","span":{"begin":990,"end":992},"obj":"20711357"},{"id":"32574271-28669880-34514623","span":{"begin":1021,"end":1023},"obj":"28669880"},{"id":"32574271-26807022-34514624","span":{"begin":1025,"end":1027},"obj":"26807022"},{"id":"32574271-17920016-34514624","span":{"begin":1025,"end":1027},"obj":"17920016"},{"id":"32574271-24305823-34514624","span":{"begin":1025,"end":1027},"obj":"24305823"},{"id":"32574271-31930911-34514625","span":{"begin":1231,"end":1233},"obj":"31930911"},{"id":"32574271-32279287-34514626","span":{"begin":1295,"end":1297},"obj":"32279287"},{"id":"32574271-26345428-34514627","span":{"begin":1299,"end":1301},"obj":"26345428"},{"id":"32574271-30791839-34514627","span":{"begin":1299,"end":1301},"obj":"30791839"},{"id":"32574271-30419930-34514627","span":{"begin":1299,"end":1301},"obj":"30419930"},{"id":"32574271-32279287-34514628","span":{"begin":1339,"end":1341},"obj":"32279287"},{"id":"32574271-31262533-34514629","span":{"begin":1343,"end":1345},"obj":"31262533"},{"id":"32574271-30966844-34514630","span":{"begin":1347,"end":1349},"obj":"30966844"},{"id":"32574271-26345428-34514631","span":{"begin":1385,"end":1387},"obj":"26345428"},{"id":"32574271-31165725-34514632","span":{"begin":1389,"end":1391},"obj":"31165725"},{"id":"32574271-21690215-34514633","span":{"begin":1478,"end":1480},"obj":"21690215"},{"id":"32574271-25187545-34514634","span":{"begin":1482,"end":1484},"obj":"25187545"},{"id":"32574271-2849510-34514635","span":{"begin":1486,"end":1488},"obj":"2849510"},{"id":"32574271-21887302-34514635","span":{"begin":1486,"end":1488},"obj":"21887302"},{"id":"32574271-31315999-34514635","span":{"begin":1486,"end":1488},"obj":"31315999"},{"id":"32574271-31266258-34514635","span":{"begin":1486,"end":1488},"obj":"31266258"},{"id":"32574271-30959796-34514635","span":{"begin":1486,"end":1488},"obj":"30959796"}],"text":"Receptor for lactoferrin Cell types where receptor are present Selected references\nLactoferrin receptor/LRP-1/CD91/apoE receptor or the chyclomicron remnant receptor Multiple tissues and cell types including intestinal epithelial cell lymphocytes, fibroblasts, neurons, hepatocytes, endothelial cells (62) (60, 69–71)\nIntelectin-1 (omentin-1) Visceral (omental and epicardial) fat, mesothelial cells, vascular cells, airway goblet cells, small intestine, colon, ovary, and plasma (66, 72)\nTLR2 and TLR4 Endothelial cells, platelets, neutrophils (73–80)\nCXCR4 Platelets, endothelial cells, neutrophils, T-cells (78, 81–83)\nCD14 Macrophages, neutrophils (62, 84, 85)\nHeparan sulfate proteoglycans (HSPGs), Epithelial cells, endothelial cells, fibroblasts, lymphocytes (86, 87)\nInterleukin 1 Various cells\nSelected molecules and entities that bind to these receptors, other than lactoferrin\nReceptor Molecule or cellular entity References\nLactoferrin receptor Bacteria (30)\nLRP-1 Amyloid beta (Aβ) (69, 88–90)\nIntelectin-1 (omentin-1) Microbial sugars, including β-D-galactofuranose (β-Galf), D-glycerol 1-phosphate, d-glycero-D-talo-oct-2-ulosonic acid (KO), and 3-deoxy-d-manno-oct-2-ulosonic acid (KDO) (91)\nTLR4 Bacterial lipopolysaccharides (LPSs) Herpex simplex (78, 92–94)\nCXCR4 Viruses (including HIV) (78, 95, 96)\nCD14 LPS, H7N9 Influenza virus (92, 97)\nHeparan sulfate proteoglycans (HSPGs) Various viruses, including HIV and SARS-CoV (86, 87, 98–102)"}