PMC:7265874 / 8713-10294 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7265874","sourcedb":"PMC","sourceid":"7265874","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7265874","text":"Abbreviations\nCOVID-19 Coronavirus disease 2019\nSARS-COV-2 virus Severe acute respiratory syndrome coronavirus 2\nICU Intensive care unit\nIPA Invasive pulmonary aspergillosis\nIAA Influenza-associated aspergillosis\nARDS Acute respiratory distress syndrome\nh Hour\nBAL Broncho-alveolar lavage\nCT Computed tomography\nEORTC European Organization for Research and Treatment of Cancer\nAspICU Aspergillosis intensive care unit\nNo Number\nSD Standard deviation\nHEPA High-efficiency particulate air filters\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\n\nAcknowledgements\nWe want to thank our entire ICU team for their unwavering commitment during these challenging times.\n\nAuthors’ contributions\nLR wrote the first draft of manuscript with input and revisions from NVR and NS. NS collected the data from the source documents. TVH and LR performed the literature search. PB and HD advised on the reporting of the clinical data; RN and HM on the reporting of the microbiological and infection prevention data. All authors had full access to all of the data. All authors read and approved the final manuscript.\n\nFunding\nNone.\n\nAvailability of data and materials\nThe datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.\n\nEthics approval and consent to participate\nPublication approval granted by the Ethics Committee.\n\nConsent for publication\nNot applicable.\n\nCompeting interests\nThe authors declare that they have no competing interests.","divisions":[{"label":"title","span":{"begin":0,"end":13}},{"label":"p","span":{"begin":23,"end":47}},{"label":"p","span":{"begin":65,"end":112}},{"label":"p","span":{"begin":117,"end":136}},{"label":"p","span":{"begin":141,"end":173}},{"label":"p","span":{"begin":178,"end":212}},{"label":"p","span":{"begin":218,"end":253}},{"label":"p","span":{"begin":256,"end":260}},{"label":"p","span":{"begin":265,"end":288}},{"label":"p","span":{"begin":292,"end":311}},{"label":"p","span":{"begin":318,"end":376}},{"label":"p","span":{"begin":384,"end":417}},{"label":"p","span":{"begin":421,"end":427}},{"label":"p","span":{"begin":431,"end":449}},{"label":"p","span":{"begin":455,"end":494}},{"label":"footnote","span":{"begin":495,"end":630}},{"label":"p","span":{"begin":495,"end":512}},{"label":"p","span":{"begin":512,"end":630}},{"label":"ack","span":{"begin":632,"end":749}},{"label":"title","span":{"begin":632,"end":648}},{"label":"p","span":{"begin":649,"end":749}},{"label":"notes","span":{"begin":751,"end":1185}},{"label":"title","span":{"begin":751,"end":773}},{"label":"p","span":{"begin":774,"end":1185}},{"label":"notes","span":{"begin":1187,"end":1200}},{"label":"title","span":{"begin":1187,"end":1194}},{"label":"p","span":{"begin":1195,"end":1200}},{"label":"notes","span":{"begin":1202,"end":1362}},{"label":"title","span":{"begin":1202,"end":1236}},{"label":"p","span":{"begin":1237,"end":1362}},{"label":"notes","span":{"begin":1364,"end":1460}},{"label":"title","span":{"begin":1364,"end":1406}},{"label":"p","span":{"begin":1407,"end":1460}},{"label":"notes","span":{"begin":1462,"end":1501}},{"label":"title","span":{"begin":1462,"end":1485}},{"label":"p","span":{"begin":1486,"end":1501}},{"label":"title","span":{"begin":1503,"end":1522}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T17","span":{"begin":273,"end":281},"obj":"Body_part"}],"attributes":[{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma264783"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T68","span":{"begin":14,"end":22},"obj":"Disease"},{"id":"T69","span":{"begin":23,"end":47},"obj":"Disease"},{"id":"T70","span":{"begin":48,"end":52},"obj":"Disease"},{"id":"T71","span":{"begin":65,"end":112},"obj":"Disease"},{"id":"T72","span":{"begin":160,"end":173},"obj":"Disease"},{"id":"T73","span":{"begin":178,"end":187},"obj":"Disease"},{"id":"T74","span":{"begin":199,"end":212},"obj":"Disease"},{"id":"T75","span":{"begin":213,"end":217},"obj":"Disease"},{"id":"T76","span":{"begin":218,"end":253},"obj":"Disease"},{"id":"T77","span":{"begin":224,"end":253},"obj":"Disease"},{"id":"T78","span":{"begin":370,"end":376},"obj":"Disease"},{"id":"T79","span":{"begin":384,"end":397},"obj":"Disease"},{"id":"T80","span":{"begin":851,"end":853},"obj":"Disease"},{"id":"T81","span":{"begin":855,"end":857},"obj":"Disease"},{"id":"T82","span":{"begin":948,"end":950},"obj":"Disease"},{"id":"T83","span":{"begin":955,"end":957},"obj":"Disease"},{"id":"T84","span":{"begin":1059,"end":1068},"obj":"Disease"}],"attributes":[{"id":"A68","pred":"mondo_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A70","pred":"mondo_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0005657"},{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0005657"},{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"},{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0005657"},{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0009735"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0009735"},{"id":"A82","pred":"mondo_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/MONDO_0019035"},{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0007739"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T57","span":{"begin":59,"end":64},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T58","span":{"begin":327,"end":339},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"}],"attributes":[{"subj":"T57","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T106","span":{"begin":137,"end":140},"obj":"Chemical"},{"id":"T108","span":{"begin":174,"end":177},"obj":"Chemical"},{"id":"T109","span":{"begin":261,"end":264},"obj":"Chemical"},{"id":"T110","span":{"begin":428,"end":430},"obj":"Chemical"},{"id":"T111","span":{"begin":774,"end":776},"obj":"Chemical"},{"id":"T112","span":{"begin":851,"end":853},"obj":"Chemical"},{"id":"T113","span":{"begin":855,"end":857},"obj":"Chemical"},{"id":"T114","span":{"begin":912,"end":914},"obj":"Chemical"},{"id":"T115","span":{"begin":948,"end":950},"obj":"Chemical"},{"id":"T117","span":{"begin":955,"end":957},"obj":"Chemical"},{"id":"T118","span":{"begin":1012,"end":1014},"obj":"Chemical"}],"attributes":[{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_17824"},{"id":"A107","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_30802"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_16411"},{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_64198"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_73528"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_73426"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_73426"},{"id":"A114","pred":"chebi_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/CHEBI_73528"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_53319"},{"id":"A116","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_60686"},{"id":"A117","pred":"chebi_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/CHEBI_73925"},{"id":"A118","pred":"chebi_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/CHEBI_74053"},{"subj":"T106","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T108","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T109","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T118","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T47","span":{"begin":137,"end":140},"obj":"Phenotype"},{"id":"T48","span":{"begin":141,"end":173},"obj":"Phenotype"},{"id":"T49","span":{"begin":224,"end":244},"obj":"Phenotype"},{"id":"T50","span":{"begin":370,"end":376},"obj":"Phenotype"}],"attributes":[{"id":"A47","pred":"hp_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/HP_0020103"},{"id":"A48","pred":"hp_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/HP_0020103"},{"id":"A49","pred":"hp_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A50","pred":"hp_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/HP_0002664"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T71","span":{"begin":0,"end":13},"obj":"Sentence"},{"id":"T72","span":{"begin":14,"end":47},"obj":"Sentence"},{"id":"T73","span":{"begin":48,"end":112},"obj":"Sentence"},{"id":"T74","span":{"begin":113,"end":136},"obj":"Sentence"},{"id":"T75","span":{"begin":137,"end":173},"obj":"Sentence"},{"id":"T76","span":{"begin":174,"end":212},"obj":"Sentence"},{"id":"T77","span":{"begin":213,"end":253},"obj":"Sentence"},{"id":"T78","span":{"begin":254,"end":260},"obj":"Sentence"},{"id":"T79","span":{"begin":261,"end":288},"obj":"Sentence"},{"id":"T80","span":{"begin":289,"end":311},"obj":"Sentence"},{"id":"T81","span":{"begin":312,"end":376},"obj":"Sentence"},{"id":"T82","span":{"begin":377,"end":417},"obj":"Sentence"},{"id":"T83","span":{"begin":418,"end":427},"obj":"Sentence"},{"id":"T84","span":{"begin":428,"end":449},"obj":"Sentence"},{"id":"T85","span":{"begin":450,"end":494},"obj":"Sentence"},{"id":"T86","span":{"begin":495,"end":511},"obj":"Sentence"},{"id":"T87","span":{"begin":512,"end":630},"obj":"Sentence"},{"id":"T88","span":{"begin":632,"end":648},"obj":"Sentence"},{"id":"T89","span":{"begin":649,"end":749},"obj":"Sentence"},{"id":"T90","span":{"begin":751,"end":773},"obj":"Sentence"},{"id":"T91","span":{"begin":774,"end":854},"obj":"Sentence"},{"id":"T92","span":{"begin":855,"end":903},"obj":"Sentence"},{"id":"T93","span":{"begin":904,"end":947},"obj":"Sentence"},{"id":"T94","span":{"begin":948,"end":1085},"obj":"Sentence"},{"id":"T95","span":{"begin":1086,"end":1133},"obj":"Sentence"},{"id":"T96","span":{"begin":1134,"end":1185},"obj":"Sentence"},{"id":"T97","span":{"begin":1187,"end":1194},"obj":"Sentence"},{"id":"T98","span":{"begin":1195,"end":1200},"obj":"Sentence"},{"id":"T99","span":{"begin":1202,"end":1236},"obj":"Sentence"},{"id":"T100","span":{"begin":1237,"end":1362},"obj":"Sentence"},{"id":"T101","span":{"begin":1364,"end":1406},"obj":"Sentence"},{"id":"T102","span":{"begin":1407,"end":1460},"obj":"Sentence"},{"id":"T103","span":{"begin":1462,"end":1485},"obj":"Sentence"},{"id":"T104","span":{"begin":1486,"end":1501},"obj":"Sentence"},{"id":"T105","span":{"begin":1503,"end":1522},"obj":"Sentence"},{"id":"T106","span":{"begin":1523,"end":1581},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T71","pred":"source","obj":"LitCovid-sentences"},{"subj":"T72","pred":"source","obj":"LitCovid-sentences"},{"subj":"T73","pred":"source","obj":"LitCovid-sentences"},{"subj":"T74","pred":"source","obj":"LitCovid-sentences"},{"subj":"T75","pred":"source","obj":"LitCovid-sentences"},{"subj":"T76","pred":"source","obj":"LitCovid-sentences"},{"subj":"T77","pred":"source","obj":"LitCovid-sentences"},{"subj":"T78","pred":"source","obj":"LitCovid-sentences"},{"subj":"T79","pred":"source","obj":"LitCovid-sentences"},{"subj":"T80","pred":"source","obj":"LitCovid-sentences"},{"subj":"T81","pred":"source","obj":"LitCovid-sentences"},{"subj":"T82","pred":"source","obj":"LitCovid-sentences"},{"subj":"T83","pred":"source","obj":"LitCovid-sentences"},{"subj":"T84","pred":"source","obj":"LitCovid-sentences"},{"subj":"T85","pred":"source","obj":"LitCovid-sentences"},{"subj":"T86","pred":"source","obj":"LitCovid-sentences"},{"subj":"T87","pred":"source","obj":"LitCovid-sentences"},{"subj":"T88","pred":"source","obj":"LitCovid-sentences"},{"subj":"T89","pred":"source","obj":"LitCovid-sentences"},{"subj":"T90","pred":"source","obj":"LitCovid-sentences"},{"subj":"T91","pred":"source","obj":"LitCovid-sentences"},{"subj":"T92","pred":"source","obj":"LitCovid-sentences"},{"subj":"T93","pred":"source","obj":"LitCovid-sentences"},{"subj":"T94","pred":"source","obj":"LitCovid-sentences"},{"subj":"T95","pred":"source","obj":"LitCovid-sentences"},{"subj":"T96","pred":"source","obj":"LitCovid-sentences"},{"subj":"T97","pred":"source","obj":"LitCovid-sentences"},{"subj":"T98","pred":"source","obj":"LitCovid-sentences"},{"subj":"T99","pred":"source","obj":"LitCovid-sentences"},{"subj":"T100","pred":"source","obj":"LitCovid-sentences"},{"subj":"T101","pred":"source","obj":"LitCovid-sentences"},{"subj":"T102","pred":"source","obj":"LitCovid-sentences"},{"subj":"T103","pred":"source","obj":"LitCovid-sentences"},{"subj":"T104","pred":"source","obj":"LitCovid-sentences"},{"subj":"T105","pred":"source","obj":"LitCovid-sentences"},{"subj":"T106","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"213","span":{"begin":23,"end":47},"obj":"Disease"},{"id":"215","span":{"begin":48,"end":58},"obj":"Species"},{"id":"217","span":{"begin":141,"end":173},"obj":"Disease"},{"id":"219","span":{"begin":174,"end":177},"obj":"Chemical"},{"id":"221","span":{"begin":199,"end":212},"obj":"Disease"},{"id":"223","span":{"begin":213,"end":217},"obj":"Disease"},{"id":"225","span":{"begin":218,"end":253},"obj":"Disease"},{"id":"227","span":{"begin":370,"end":376},"obj":"Disease"},{"id":"229","span":{"begin":428,"end":430},"obj":"Disease"},{"id":"232","span":{"begin":955,"end":957},"obj":"Disease"},{"id":"233","span":{"begin":1059,"end":1068},"obj":"Disease"}],"attributes":[{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"MESH:C000657245"},{"id":"A215","pred":"tao:has_database_id","subj":"215","obj":"Tax:2697049"},{"id":"A217","pred":"tao:has_database_id","subj":"217","obj":"MESH:D055744"},{"id":"A221","pred":"tao:has_database_id","subj":"221","obj":"MESH:D001228"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"MESH:D012128"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"MESH:D012128"},{"id":"A227","pred":"tao:has_database_id","subj":"227","obj":"MESH:D009369"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"MESH:D029461"},{"id":"A232","pred":"tao:has_database_id","subj":"232","obj":"MESH:D006816"},{"id":"A233","pred":"tao:has_database_id","subj":"233","obj":"MESH:D007239"},{"subj":"213","pred":"source","obj":"LitCovid-PubTator"},{"subj":"215","pred":"source","obj":"LitCovid-PubTator"},{"subj":"217","pred":"source","obj":"LitCovid-PubTator"},{"subj":"219","pred":"source","obj":"LitCovid-PubTator"},{"subj":"221","pred":"source","obj":"LitCovid-PubTator"},{"subj":"223","pred":"source","obj":"LitCovid-PubTator"},{"subj":"225","pred":"source","obj":"LitCovid-PubTator"},{"subj":"227","pred":"source","obj":"LitCovid-PubTator"},{"subj":"229","pred":"source","obj":"LitCovid-PubTator"},{"subj":"232","pred":"source","obj":"LitCovid-PubTator"},{"subj":"233","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#939bec","default":true},{"id":"LitCovid-PD-MONDO","color":"#b5ec93"},{"id":"LitCovid-PD-CLO","color":"#ec93cf"},{"id":"LitCovid-PD-CHEBI","color":"#93e9ec"},{"id":"LitCovid-PD-HP","color":"#ecd493"},{"id":"LitCovid-sentences","color":"#ba93ec"},{"id":"LitCovid-PubTator","color":"#93eca0"}]}]}}