PMC:7264098 / 6066-6424 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T141","span":{"begin":74,"end":82},"obj":"SP_7"},{"id":"T142","span":{"begin":91,"end":95},"obj":"UBERON:0002048"},{"id":"T48220","span":{"begin":74,"end":82},"obj":"SP_7"},{"id":"T56905","span":{"begin":91,"end":95},"obj":"UBERON:0002048"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PubTator","denotations":[{"id":"155","span":{"begin":20,"end":32},"obj":"Disease"},{"id":"156","span":{"begin":74,"end":82},"obj":"Disease"},{"id":"157","span":{"begin":91,"end":102},"obj":"Disease"}],"attributes":[{"id":"A155","pred":"tao:has_database_id","subj":"155","obj":"MESH:D007249"},{"id":"A156","pred":"tao:has_database_id","subj":"156","obj":"MESH:C000657245"},{"id":"A157","pred":"tao:has_database_id","subj":"157","obj":"MESH:D008171"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T52","span":{"begin":6,"end":15},"obj":"Body_part"},{"id":"T53","span":{"begin":91,"end":95},"obj":"Body_part"},{"id":"T54","span":{"begin":151,"end":159},"obj":"Body_part"}],"attributes":[{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":91,"end":95},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T46","span":{"begin":20,"end":32},"obj":"Disease"},{"id":"T47","span":{"begin":74,"end":82},"obj":"Disease"}],"attributes":[{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T78","span":{"begin":91,"end":95},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T79","span":{"begin":91,"end":95},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T80","span":{"begin":333,"end":334},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T10","span":{"begin":20,"end":32},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-sentences","denotations":[{"id":"T37","span":{"begin":0,"end":199},"obj":"Sentence"},{"id":"T38","span":{"begin":200,"end":358},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":151,"end":165},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"Since cytokines and inflammation play dominant role in the development of COVID-19-induced lung damage, immunological therapies capable of attenuating cytokine storm may be the key treatment options. However, traditional immunomodulatory capacity of common immunotherapeutics are targeted at one or two factors, which may not induce a strong enough response."}