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PMC:7264098 / 21057-23119 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T308 52-63 GO:0006412 denotes translation
T309 120-128 SP_7 denotes COVID-19
T310 137-141 UBERON:0002048 denotes lung
T311 376-386 CL:0000034 denotes Stem cells
T312 627-631 UBERON:0002048 denotes lung
T313 726-736 CL:0000034 denotes stem cells
T314 780-789 CL:0000034 denotes stem cell
T315 823-843 GO:0031012 denotes extracellular matrix
T316 962-966 DG_47 denotes MSCs
T317 980-995 CHEBI:52217;CHEBI:52217 denotes pharmacological
T318 1050-1056 UBERON:0000479;GO:0006281 denotes tissue
T319 1057-1063 GO:0006281 denotes repair
T320 1212-1225 GO:0048468 denotes production of
T321 1226-1236 CL:0000034 denotes stem cells
T322 1290-1298 CL:0000034 denotes stemness
T323 1316-1324 GO:0007567 denotes delivery
T324 1480-1490 CL:0000034 denotes stem cells
T325 1604-1614 CL:0000034 denotes stem cells
T326 1725-1735 CL:0000034 denotes stem cells
T327 1787-1797 GO:0065007 denotes regulating
T328 1819-1842 CL:0000034 denotes transplanted stem cells
T329 1942-1951 UBERON:0002048 denotes pulmonary
T330 1990-1996 UBERON:0000062 denotes organs
T331 2052-2061 CHEBI:75958;CHEBI:75958 denotes solutions
T55749 52-63 GO:0006412 denotes translation
T96268 120-128 SP_7 denotes COVID-19
T69032 137-141 UBERON:0002048 denotes lung
T95394 376-386 CL:0000034 denotes Stem cells
T83780 627-631 UBERON:0002048 denotes lung
T98945 726-736 CL:0000034 denotes stem cells
T52104 780-789 CL:0000034 denotes stem cell
T53274 823-843 GO:0031012 denotes extracellular matrix
T54541 962-966 DG_47 denotes MSCs
T40739 980-995 CHEBI:52217;CHEBI:52217 denotes pharmacological
T46992 1050-1056 UBERON:0000479;GO:0006281 denotes tissue
T78120 1057-1063 GO:0006281 denotes repair
T15894 1212-1225 GO:0048468 denotes production of
T72307 1226-1236 CL:0000034 denotes stem cells
T85415 1290-1298 CL:0000034 denotes stemness
T40588 1316-1324 GO:0007567 denotes delivery
T94244 1480-1490 CL:0000034 denotes stem cells
T10093 1604-1614 CL:0000034 denotes stem cells
T55372 1725-1735 CL:0000034 denotes stem cells
T36985 1787-1797 GO:0065007 denotes regulating
T99669 1819-1842 CL:0000034 denotes transplanted stem cells
T26729 1942-1951 UBERON:0002048 denotes pulmonary
T45660 1990-1996 UBERON:0000062 denotes organs
T90606 2052-2061 CHEBI:75958;CHEBI:75958 denotes solutions

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
436 120-128 Disease denotes COVID-19 MESH:C000657245
437 137-150 Disease denotes lung injuries MESH:D055370
438 452-459 Disease denotes hypoxia MESH:D000860
439 463-471 Disease denotes ischemia MESH:D007511
442 1328-1336 Species denotes patients Tax:9606
443 1500-1508 Species denotes patients Tax:9606

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T154 137-141 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T155 369-374 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 376-386 Body_part denotes Stem cells http://purl.org/sig/ont/fma/fma63368
T157 381-386 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T158 580-585 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T159 627-631 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T160 726-736 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T161 731-736 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T162 780-789 Body_part denotes stem cell http://purl.org/sig/ont/fma/fma63368
T163 785-789 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T164 823-843 Body_part denotes extracellular matrix http://purl.org/sig/ont/fma/fma9672
T165 888-892 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T166 1050-1056 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T167 1226-1236 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T168 1231-1236 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T169 1480-1490 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T170 1485-1490 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T171 1604-1614 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T172 1609-1614 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T173 1625-1629 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T174 1725-1735 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T175 1730-1735 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 1832-1842 Body_part denotes stem cells http://purl.org/sig/ont/fma/fma63368
T177 1837-1842 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T38 137-141 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T39 627-631 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T40 1050-1056 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T41 1206-1211 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T42 1990-1996 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T139 120-128 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 463-471 Disease denotes ischemia http://purl.obolibrary.org/obo/MONDO_0005053

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T221 137-141 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T222 137-141 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T223 167-168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T224 369-374 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T225 376-386 http://purl.obolibrary.org/obo/CL_0000034 denotes Stem cells
T226 498-507 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T227 580-585 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T228 627-631 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T229 627-631 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T230 726-736 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T231 780-789 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cell
T232 888-892 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T233 1085-1087 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T234 1085-1087 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T235 1089-1093 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T236 1198-1199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T237 1226-1236 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T238 1351-1355 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T239 1480-1490 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T240 1604-1614 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T241 1625-1635 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T242 1725-1735 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T243 1807-1815 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T244 1832-1842 http://purl.obolibrary.org/obo/CL_0000034 denotes stem cells
T245 1990-1996 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T66 1085-1087 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T67 1712-1720 Chemical denotes carriers http://purl.obolibrary.org/obo/CHEBI_78059

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T27 52-63 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T28 498-516 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T29 498-507 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T30 749-758 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T31 785-800 http://purl.obolibrary.org/obo/GO_0098743 denotes cell aggregates
T32 844-853 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T124 0-36 Sentence denotes Factors Affecting the Quality of MSC
T125 37-187 Sentence denotes The successful translation of MSC-based therapies into the clinic for treatment of COVID-19-induced lung injuries is dependent on a number of factors.
T126 188-375 Sentence denotes In addition to desirable therapeutic effects, it is also important to understand the mechanism of action and the influence of various in vivo environments on the integrity of these cells.
T127 376-692 Sentence denotes Stem cells can be environmentally preconditioned by certain stimuli such as hypoxia or ischemia, which can induce certain signaling pathways to improve engraftment, survival, and function of transplanted cells in harsh environments within the injured lung (Sart et al., 2014; Kim et al., 2015; Saparov et al., 2016).
T128 693-944 Sentence denotes Other methods of preconditioning stem cells include the formation of three-dimensional stem cell aggregates that lead to enhanced extracellular matrix secretion, anti-inflammatory properties and cell survival (Bartosh et al., 2010; Sart et al., 2014).
T129 945-1095 Sentence denotes Pre-treatment of MSCs with various pharmacological factors can, in fact, improve therapeutic effects and tissue repair capabilities (Hu and Li, 2018).
T130 1096-1357 Sentence denotes Furthermore, bioengineering approaches such as the use of bioreactors can overcome the limitations of a large scale production of stem cells necessary for transplantation and maintenance of the stemness during and after delivery to patients (Madl et al., 2018).
T131 1358-1509 Sentence denotes Therefore, these technologies can accelerate the transition from bench to bedside without compromising the quality of the stem cells reaching patients.
T132 1510-1675 Sentence denotes For example, tuneable materials can be used as an artificial niche to expand or differentiate stem cells to mature cell types (Yang et al., 2014; Madl et al., 2017).
T133 1676-1889 Sentence denotes Materials such as hydrogels used as carriers for stem cells can also lead to enhanced regenerative response by regulating fate and activity of transplanted stem cells (Engler et al., 2006; Chaudhuri et al., 2016).
T134 1890-2062 Sentence denotes These approaches are currently less widely used for pulmonary applications compared to other target organs and thus future investigations will lead to innovative solutions.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T17 452-459 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418

2_test

Id Subject Object Predicate Lexical cue
32574317-25126478-31466327 646-650 25126478 denotes 2014
32574317-25709098-31466328 664-668 25709098 denotes 2015
32574317-27822228-31466329 686-690 27822228 denotes 2016
32574317-20643923-31466330 919-923 20643923 denotes 2010
32574317-25126478-31466331 938-942 25126478 denotes 2014
32574317-29392844-31466332 1089-1093 29392844 denotes 2018
32574317-29769665-31466333 1351-1355 29769665 denotes 2018
32574317-24633344-31466334 1650-1654 24633344 denotes 2014
32574317-29115291-31466335 1669-1673 29115291 denotes 2017
32574317-16923388-31466336 1859-1863 16923388 denotes 2006
32574317-26618884-31466337 1883-1887 26618884 denotes 2016

MyTest

Id Subject Object Predicate Lexical cue
32574317-25126478-31466327 646-650 25126478 denotes 2014
32574317-25709098-31466328 664-668 25709098 denotes 2015
32574317-27822228-31466329 686-690 27822228 denotes 2016
32574317-20643923-31466330 919-923 20643923 denotes 2010
32574317-25126478-31466331 938-942 25126478 denotes 2014
32574317-29392844-31466332 1089-1093 29392844 denotes 2018
32574317-29769665-31466333 1351-1355 29769665 denotes 2018
32574317-24633344-31466334 1650-1654 24633344 denotes 2014
32574317-29115291-31466335 1669-1673 29115291 denotes 2017
32574317-16923388-31466336 1859-1863 16923388 denotes 2006
32574317-26618884-31466337 1883-1887 26618884 denotes 2016