PMC:7264098 / 10406-12095
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T209 | 205-213 | SP_7 | denotes | COVID-19 |
T210 | 385-390 | UBERON:0007023 | denotes | adult |
T211 | 476-491 | CHEBI:52217;CHEBI:52217 | denotes | pharmacological |
T212 | 552-557 | NCBITaxon:10239 | denotes | viral |
T213 | 577-601 | CHEBI:67079;CHEBI:67079 | denotes | anti-inflammatory agents |
T214 | 669-677 | GO:0035376 | denotes | entry of |
T215 | 682-687 | NCBITaxon:10239 | denotes | virus |
T216 | 731-736 | NCBITaxon:10239 | denotes | viral |
T217 | 737-744 | SO:0000704 | denotes | genetic |
T218 | 763-769 | UBERON:0002405;GO:0006955 | denotes | immune |
T219 | 770-778 | GO:0006955 | denotes | response |
T220 | 858-866 | SP_10 | denotes | SARS-CoV |
T221 | 871-879 | SP_9 | denotes | MERS-CoV |
T222 | 1063-1071 | SP_10 | denotes | SARS-CoV |
T223 | 1238-1247 | DG_29 | denotes | ribavirin |
T224 | 1317-1321 | SP_9 | denotes | MERS |
T225 | 1543-1548 | SP_6;NCBITaxon:9606 | denotes | human |
T226 | 1603-1609 | NCBITaxon:9606 | denotes | people |
T19107 | 205-213 | SP_7 | denotes | COVID-19 |
T18999 | 385-390 | UBERON:0007023 | denotes | adult |
T82295 | 476-491 | CHEBI:52217;CHEBI:52217 | denotes | pharmacological |
T38095 | 552-557 | NCBITaxon:10239 | denotes | viral |
T83805 | 577-601 | CHEBI:67079;CHEBI:67079 | denotes | anti-inflammatory agents |
T45166 | 669-677 | GO:0035376 | denotes | entry of |
T6847 | 682-687 | NCBITaxon:10239 | denotes | virus |
T60882 | 731-736 | NCBITaxon:10239 | denotes | viral |
T38954 | 737-744 | SO:0000704 | denotes | genetic |
T73828 | 763-769 | UBERON:0002405;GO:0006955 | denotes | immune |
T2948 | 770-778 | GO:0006955 | denotes | response |
T72804 | 858-866 | SP_10 | denotes | SARS-CoV |
T63585 | 871-879 | SP_9 | denotes | MERS-CoV |
T57772 | 1063-1071 | SP_10 | denotes | SARS-CoV |
T4874 | 1238-1247 | DG_29 | denotes | ribavirin |
T72833 | 1317-1321 | SP_9 | denotes | MERS |
T51389 | 1543-1548 | SP_6;NCBITaxon:9606 | denotes | human |
T46048 | 1603-1609 | NCBITaxon:9606 | denotes | people |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
266 | 391-399 | Species | denotes | patients | Tax:9606 |
267 | 858-866 | Species | denotes | SARS-CoV | Tax:694009 |
268 | 871-879 | Species | denotes | MERS-CoV | Tax:1335626 |
269 | 1063-1071 | Species | denotes | SARS-CoV | Tax:694009 |
270 | 1543-1548 | Species | denotes | human | Tax:9606 |
271 | 1603-1609 | Species | denotes | people | Tax:9606 |
272 | 1238-1247 | Chemical | denotes | ribavirin | MESH:D012254 |
273 | 205-213 | Disease | denotes | COVID-19 | MESH:C000657245 |
274 | 779-791 | Disease | denotes | inflammation | MESH:D007249 |
275 | 1172-1176 | Disease | denotes | ARDS | MESH:D012128 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T73 | 424-427 | Body_part | denotes | arm | http://purl.org/sig/ont/fma/fma24890 |
T74 | 698-703 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T19 | 424-427 | Body_part | denotes | arm | http://purl.obolibrary.org/obo/UBERON_0001460 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T80 | 205-213 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T81 | 779-791 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T82 | 858-866 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T83 | 858-862 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T84 | 1063-1071 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T85 | 1063-1067 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T86 | 1172-1176 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T113 | 17-23 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T114 | 59-60 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T115 | 424-427 | http://www.ebi.ac.uk/efo/EFO_0001410 | denotes | arm |
T116 | 682-687 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T117 | 698-703 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T118 | 956-960 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
T119 | 1337-1341 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
T120 | 1504-1505 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T121 | 1543-1548 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T36 | 577-601 | Chemical | denotes | anti-inflammatory agents | http://purl.obolibrary.org/obo/CHEBI_67079 |
T37 | 1238-1247 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
T38 | 1252-1262 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T17 | 763-778 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T18 | 779-791 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T60 | 0-252 | Sentence | denotes | Despite over 300 active and recruiting clinical trials and a number of trials already completed, there is still no robust evidence that any of the investigated therapeutics are effective as treatments for COVID-19 disease (Channappanavar et al., 2017). |
T61 | 253-347 | Sentence | denotes | Equally, there is no evidence to support prophylactic treatment either (Sanders et al., 2020). |
T62 | 348-458 | Sentence | denotes | However, there are only 29 trials in adult patients with placebo-controlled arm (Channappanavar et al., 2017). |
T63 | 459-602 | Sentence | denotes | Various types of pharmacological treatments are currently under investigation including anti-viral, anti-malarial and anti-inflammatory agents. |
T64 | 603-792 | Sentence | denotes | These therapies generally target the following processes: (1) the entry of the virus into host cells, (2) multiplication of the viral genetic material, and (3) immune response/inflammation. |
T65 | 793-1026 | Sentence | denotes | Most of these agents have been previously used as treatments for SARS-CoV and MERS-CoV, however the overall conclusions of the meta-analyses published in 2006 and 2018, respectively, did not support the use of any particular regimen. |
T66 | 1027-1209 | Sentence | denotes | In relation to the meta-analysis of SARS-CoV treatments, the authors systematically reviewed 54 treatment studies, 15 in vitro studies and three ARDS studies (Stockman et al., 2006). |
T67 | 1210-1419 | Sentence | denotes | Although the combination of ribavirin and interferon-based (IFN) treatments appears the most effective for MERS (Morra et al., 2018), this needs to be confirmed in randomized placebo-controlled trial settings. |
T68 | 1420-1689 | Sentence | denotes | In terms of vaccines, there are at least 115 vaccine candidates in development with a number of these already initiated in human trials, however we expect vaccines to be available to people under emergency use only in early 2021 (Callaway, 2020; Thanh Le et al., 2020). |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574317-28373583-31466304 | 246-250 | 28373583 | denotes | 2017 |
32574317-32282022-31466305 | 341-345 | 32282022 | denotes | 2020 |
32574317-28373583-31466306 | 452-456 | 28373583 | denotes | 2017 |
32574317-16968120-31466307 | 1203-1207 | 16968120 | denotes | 2006 |
32574317-29664167-31466308 | 1337-1341 | 29664167 | denotes | 2018 |
32574317-32346146-31466309 | 1660-1664 | 32346146 | denotes | 2020 |
32574317-32273591-31466310 | 1683-1687 | 32273591 | denotes | 2020 |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32574317-28373583-31466304 | 246-250 | 28373583 | denotes | 2017 |
32574317-32282022-31466305 | 341-345 | 32282022 | denotes | 2020 |
32574317-28373583-31466306 | 452-456 | 28373583 | denotes | 2017 |
32574317-16968120-31466307 | 1203-1207 | 16968120 | denotes | 2006 |
32574317-29664167-31466308 | 1337-1341 | 29664167 | denotes | 2018 |
32574317-32346146-31466309 | 1660-1664 | 32346146 | denotes | 2020 |
32574317-32273591-31466310 | 1683-1687 | 32273591 | denotes | 2020 |