PMC:7258756 / 32241-32916 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"475","span":{"begin":319,"end":320},"obj":"Gene"},{"id":"476","span":{"begin":263,"end":271},"obj":"Species"},{"id":"477","span":{"begin":601,"end":609},"obj":"Species"}],"attributes":[{"id":"A475","pred":"tao:has_database_id","subj":"475","obj":"Gene:43740575"},{"id":"A476","pred":"tao:has_database_id","subj":"476","obj":"Tax:9606"},{"id":"A477","pred":"tao:has_database_id","subj":"477","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T219","span":{"begin":169,"end":175},"obj":"Body_part"},{"id":"T220","span":{"begin":229,"end":235},"obj":"Body_part"},{"id":"T221","span":{"begin":237,"end":242},"obj":"Body_part"},{"id":"T222","span":{"begin":247,"end":252},"obj":"Body_part"},{"id":"T223","span":{"begin":321,"end":325},"obj":"Body_part"},{"id":"T224","span":{"begin":396,"end":402},"obj":"Body_part"},{"id":"T225","span":{"begin":568,"end":574},"obj":"Body_part"},{"id":"T226","span":{"begin":622,"end":628},"obj":"Body_part"},{"id":"T227","span":{"begin":662,"end":665},"obj":"Body_part"}],"attributes":[{"id":"A219","pred":"fma_id","subj":"T219","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A220","pred":"fma_id","subj":"T220","obj":"http://purl.org/sig/ont/fma/fma312401"},{"id":"A221","pred":"fma_id","subj":"T221","obj":"http://purl.org/sig/ont/fma/fma12274"},{"id":"A222","pred":"fma_id","subj":"T222","obj":"http://purl.org/sig/ont/fma/fma64183"},{"id":"A223","pred":"fma_id","subj":"T223","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A224","pred":"fma_id","subj":"T224","obj":"http://purl.org/sig/ont/fma/fma312401"},{"id":"A225","pred":"fma_id","subj":"T225","obj":"http://purl.org/sig/ont/fma/fma59862"},{"id":"A226","pred":"fma_id","subj":"T226","obj":"http://purl.org/sig/ont/fma/fma59862"},{"id":"A227","pred":"fma_id","subj":"T227","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T7","span":{"begin":229,"end":235},"obj":"Body_part"},{"id":"T8","span":{"begin":237,"end":242},"obj":"Body_part"},{"id":"T9","span":{"begin":247,"end":252},"obj":"Body_part"},{"id":"T10","span":{"begin":396,"end":402},"obj":"Body_part"},{"id":"T11","span":{"begin":568,"end":574},"obj":"Body_part"},{"id":"T12","span":{"begin":622,"end":628},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0007311"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0001088"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0001988"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0007311"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0001836"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0001836"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T171","span":{"begin":33,"end":35},"obj":"Disease"},{"id":"T173","span":{"begin":389,"end":391},"obj":"Disease"}],"attributes":[{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0010979"},{"id":"A172","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0016455"},{"id":"A173","pred":"mondo_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/MONDO_0010979"},{"id":"A174","pred":"mondo_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/MONDO_0016455"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T258","span":{"begin":156,"end":157},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T259","span":{"begin":321,"end":325},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T260","span":{"begin":542,"end":547},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T261","span":{"begin":588,"end":590},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T262","span":{"begin":629,"end":636},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T135","span":{"begin":33,"end":35},"obj":"Chemical"},{"id":"T136","span":{"begin":389,"end":391},"obj":"Chemical"}],"attributes":[{"id":"A135","pred":"chebi_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/CHEBI_73664"},{"id":"A136","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_73664"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"LitCovid-sentences","denotations":[{"id":"T216","span":{"begin":0,"end":176},"obj":"Sentence"},{"id":"T217","span":{"begin":177,"end":318},"obj":"Sentence"},{"id":"T218","span":{"begin":319,"end":519},"obj":"Sentence"},{"id":"T219","span":{"begin":520,"end":675},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}

{"project":"2_test","denotations":[{"id":"32242873-31950516-47036570","span":{"begin":478,"end":481},"obj":"31950516"},{"id":"T37244","span":{"begin":478,"end":481},"obj":"31950516"}],"text":"The low viral copy number of the TS specimen from case 2 could be the possible reason for lesser viral reads being retrieved during the NGS run, leading to a fragmented genome. The recent study from China on serial samples (TSs, sputum, urine and stool) from two patients followed days 3-12 and days 4-15 post onset20. N gene-specific real-time RT-PCR assay showed that the viral loads in TS and sputum samples peaked at around 5-6 days after symptom onset, ranging from around 104-107 copies per ml during this time20. In another study, the virus was detected in the saliva specimens of 11 of the 12 patients, and serial saliva testing showed declines of viral RNA levels21."}