PMC:7253482 / 15015-15383
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T91 | 23-33 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
T92 | 284-289 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T4 | 284-289 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T90 | 210-212 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T91 | 210-212 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T92 | 240-247 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T172 | 23-28 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T173 | 29-33 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T174 | 210-212 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T175 | 240-247 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sample-MedDRA
Id | Subject | Object | Predicate | Lexical cue | meddra_id |
---|---|---|---|---|---|
T5 | 87-110 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | neutralizing antibodies | http://purl.bioontology.org/ontology/MEDDRA/10058063 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T41 | 335-345 | http://purl.obolibrary.org/obo/BFO_0000034 | denotes | functional |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18701 | 0-7 | RB | denotes | Firstly |
T74266 | 7-8 | -COMMA- | denotes | , |
T36827 | 9-11 | PRP | denotes | we |
T39186 | 12-17 | VBD | denotes | found |
T6773 | 18-22 | IN | denotes | that |
T13224 | 23-33 | JJ | denotes | amino-acid |
T54008 | 34-43 | NN | denotes | diversity |
T35302 | 44-47 | VBD | denotes | was |
T93591 | 48-56 | VBN | denotes | elevated |
T90961 | 57-59 | IN | denotes | at |
T69090 | 60-65 | VBN | denotes | known |
T86793 | 66-74 | NNS | denotes | epitopes |
T61088 | 75-83 | VBN | denotes | targeted |
T53019 | 84-86 | IN | denotes | by |
T30461 | 87-99 | VBG | denotes | neutralizing |
T32200 | 100-110 | NNS | denotes | antibodies |
T83554 | 110-111 | -COMMA- | denotes | , |
T32640 | 112-116 | JJ | denotes | such |
T51281 | 117-119 | IN | denotes | as |
T69890 | 120-123 | DT | denotes | the |
T83248 | 124-134 | JJ | denotes | N-terminal |
T49099 | 135-141 | NN | denotes | domain |
T58919 | 142-145 | CC | denotes | and |
T18721 | 146-149 | DT | denotes | the |
T18570 | 150-166 | JJ | denotes | receptor-binding |
T60790 | 167-174 | NNS | denotes | domains |
T18812 | 174-175 | -COMMA- | denotes | , |
T96660 | 176-179 | CC | denotes | and |
T11216 | 180-187 | VBN | denotes | reduced |
T27277 | 188-190 | IN | denotes | in |
T89562 | 191-194 | DT | denotes | the |
T7777 | 195-202 | NNS | denotes | regions |
T23472 | 203-205 | IN | denotes | in |
T66095 | 206-209 | DT | denotes | the |
T52990 | 210-212 | NN | denotes | S2 |
T69246 | 213-219 | NN | denotes | domain |
T76095 | 219-220 | -COMMA- | denotes | , |
T33023 | 221-225 | JJ | denotes | such |
T94778 | 226-228 | IN | denotes | as |
T12698 | 229-232 | DT | denotes | the |
T82633 | 233-239 | NN | denotes | fusion |
T75213 | 240-247 | NN | denotes | peptide |
T29294 | 247-248 | -COMMA- | denotes | , |
T28968 | 249-255 | NN | denotes | heptad |
T29760 | 256-262 | NN | denotes | repeat |
T53742 | 263-266 | CD | denotes | one |
T18725 | 266-267 | -COMMA- | denotes | , |
T43420 | 268-271 | CC | denotes | and |
T34460 | 272-275 | DT | denotes | the |
T26621 | 276-283 | JJ | denotes | central |
T91466 | 284-289 | NN | denotes | helix |
T93319 | 290-297 | NNS | denotes | domains |
T88231 | 297-298 | -COMMA- | denotes | , |
T49934 | 299-304 | WDT | denotes | which |
T23715 | 305-308 | VBP | denotes | are |
T33407 | 309-315 | RB | denotes | likely |
T88882 | 316-323 | JJ | denotes | subject |
T76117 | 324-326 | TO | denotes | to |
T4874 | 327-334 | JJR | denotes | greater |
T38302 | 335-345 | JJ | denotes | functional |
T99472 | 346-357 | NNS | denotes | constraints |
T34520 | 358-359 | -LRB- | denotes | ( |
T48991 | 359-366 | NN | denotes | Fig. 4a |
T5319 | 366-367 | -RRB- | denotes | ) |
R54626 | T39186 | T18701 | arg1Of | found,Firstly |
R55552 | T39186 | T74266 | arg1Of | found,"," |
R48506 | T36827 | T39186 | arg1Of | we,found |
R85227 | T93591 | T39186 | arg2Of | elevated,found |
R94248 | T93591 | T6773 | arg1Of | elevated,that |
R56819 | T54008 | T13224 | arg1Of | diversity,amino-acid |
R12367 | T54008 | T35302 | arg1Of | diversity,was |
R36961 | T93591 | T35302 | arg2Of | elevated,was |
R67157 | T54008 | T93591 | arg2Of | diversity,elevated |
R98710 | T93591 | T90961 | arg1Of | elevated,at |
R55146 | T86793 | T90961 | arg2Of | epitopes,at |
R5883 | T86793 | T69090 | arg2Of | epitopes,known |
R17754 | T32200 | T61088 | arg1Of | antibodies,targeted |
R9367 | T86793 | T61088 | arg2Of | epitopes,targeted |
R83504 | T32200 | T53019 | arg2Of | antibodies,by |
R74212 | T32200 | T30461 | arg1Of | antibodies,neutralizing |
R10411 | T32200 | T83554 | arg1Of | antibodies,"," |
R98281 | T51281 | T32640 | arg1Of | as,such |
R81049 | T32200 | T51281 | arg1Of | antibodies,as |
R6966 | T58919 | T51281 | arg2Of | and,as |
R21530 | T49099 | T69890 | arg1Of | domain,the |
R64448 | T49099 | T83248 | arg1Of | domain,N-terminal |
R49770 | T49099 | T58919 | arg1Of | domain,and |
R65608 | T60790 | T58919 | arg2Of | domains,and |
R95057 | T60790 | T18721 | arg1Of | domains,the |
R69352 | T60790 | T18570 | arg1Of | domains,receptor-binding |
R16170 | T96660 | T18812 | arg1Of | and,"," |
R74990 | T61088 | T96660 | arg1Of | targeted,and |
R8726 | T11216 | T96660 | arg2Of | reduced,and |
R71690 | T86793 | T11216 | arg2Of | epitopes,reduced |
R89891 | T11216 | T27277 | arg1Of | reduced,in |
R47563 | T7777 | T27277 | arg2Of | regions,in |
R49965 | T7777 | T89562 | arg1Of | regions,the |
R85283 | T7777 | T23472 | arg1Of | regions,in |
R56401 | T69246 | T23472 | arg2Of | domain,in |
R32729 | T69246 | T66095 | arg1Of | domain,the |
R3287 | T69246 | T52990 | arg1Of | domain,S2 |
R10516 | T86793 | T76095 | arg1Of | epitopes,"," |
R16608 | T94778 | T33023 | arg1Of | as,such |
R96223 | T86793 | T94778 | arg1Of | epitopes,as |
R16738 | T43420 | T94778 | arg2Of | and,as |
R3992 | T75213 | T12698 | arg1Of | peptide,the |
R20067 | T75213 | T82633 | arg1Of | peptide,fusion |
R62161 | T75213 | T29294 | arg1Of | peptide,"," |
R83184 | T29760 | T29294 | arg2Of | repeat,"," |
R27719 | T29760 | T28968 | arg1Of | repeat,heptad |
R49150 | T29760 | T53742 | arg1Of | repeat,one |
R38048 | T43420 | T18725 | arg1Of | and,"," |
R84039 | T75213 | T43420 | arg1Of | peptide,and |
R65597 | T93319 | T43420 | arg2Of | domains,and |
R93652 | T93319 | T34460 | arg1Of | domains,the |
R84393 | T93319 | T26621 | arg1Of | domains,central |
R23746 | T93319 | T91466 | arg1Of | domains,helix |
R18674 | T93319 | T88231 | arg1Of | domains,"," |
R28527 | T93319 | T49934 | arg1Of | domains,which |
R95251 | T93319 | T23715 | arg1Of | domains,are |
R68137 | T88882 | T23715 | arg2Of | subject,are |
R82494 | T88882 | T33407 | arg1Of | subject,likely |
R84782 | T93319 | T88882 | arg1Of | domains,subject |
R15085 | T88882 | T76117 | arg1Of | subject,to |
R84300 | T99472 | T76117 | arg2Of | constraints,to |
R3107 | T99472 | T4874 | arg1Of | constraints,greater |
R96110 | T99472 | T38302 | arg1Of | constraints,functional |
R31642 | T99472 | T34520 | arg1Of | constraints,( |
R75726 | T48991 | T34520 | arg2Of | Fig. 4a,( |
R85323 | T5319 | T34520 | arg3Of | ),( |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T90 | 23-33 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
T91 | 284-289 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T126 | 23-28 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T127 | 240-247 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T89 | 0-368 | Sentence | denotes | Firstly, we found that amino-acid diversity was elevated at known epitopes targeted by neutralizing antibodies, such as the N-terminal domain and the receptor-binding domains, and reduced in the regions in the S2 domain, such as the fusion peptide, heptad repeat one, and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a). |
LitCovid-sample-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T4 | 284-289 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T89 | 0-368 | Sentence | denotes | Firstly, we found that amino-acid diversity was elevated at known epitopes targeted by neutralizing antibodies, such as the N-terminal domain and the receptor-binding domains, and reduced in the regions in the S2 domain, such as the fusion peptide, heptad repeat one, and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a). |