PMC:7253482 / 15015-15383
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T91 | 23-33 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T92 | 284-289 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T4 | 284-289 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T90 | 210-212 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T91 | 210-212 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T92 | 240-247 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T172 | 23-28 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T173 | 29-33 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T174 | 210-212 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T175 | 240-247 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sample-MedDRA
| Id | Subject | Object | Predicate | Lexical cue | meddra_id |
|---|---|---|---|---|---|
| T5 | 87-110 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | neutralizing antibodies | http://purl.bioontology.org/ontology/MEDDRA/10058063 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T41 | 335-345 | http://purl.obolibrary.org/obo/BFO_0000034 | denotes | functional |
LitCovid-sample-Enju
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T18701 | 0-7 | RB | denotes | Firstly |
| T74266 | 7-8 | -COMMA- | denotes | , |
| T36827 | 9-11 | PRP | denotes | we |
| T39186 | 12-17 | VBD | denotes | found |
| T6773 | 18-22 | IN | denotes | that |
| T13224 | 23-33 | JJ | denotes | amino-acid |
| T54008 | 34-43 | NN | denotes | diversity |
| T35302 | 44-47 | VBD | denotes | was |
| T93591 | 48-56 | VBN | denotes | elevated |
| T90961 | 57-59 | IN | denotes | at |
| T69090 | 60-65 | VBN | denotes | known |
| T86793 | 66-74 | NNS | denotes | epitopes |
| T61088 | 75-83 | VBN | denotes | targeted |
| T53019 | 84-86 | IN | denotes | by |
| T30461 | 87-99 | VBG | denotes | neutralizing |
| T32200 | 100-110 | NNS | denotes | antibodies |
| T83554 | 110-111 | -COMMA- | denotes | , |
| T32640 | 112-116 | JJ | denotes | such |
| T51281 | 117-119 | IN | denotes | as |
| T69890 | 120-123 | DT | denotes | the |
| T83248 | 124-134 | JJ | denotes | N-terminal |
| T49099 | 135-141 | NN | denotes | domain |
| T58919 | 142-145 | CC | denotes | and |
| T18721 | 146-149 | DT | denotes | the |
| T18570 | 150-166 | JJ | denotes | receptor-binding |
| T60790 | 167-174 | NNS | denotes | domains |
| T18812 | 174-175 | -COMMA- | denotes | , |
| T96660 | 176-179 | CC | denotes | and |
| T11216 | 180-187 | VBN | denotes | reduced |
| T27277 | 188-190 | IN | denotes | in |
| T89562 | 191-194 | DT | denotes | the |
| T7777 | 195-202 | NNS | denotes | regions |
| T23472 | 203-205 | IN | denotes | in |
| T66095 | 206-209 | DT | denotes | the |
| T52990 | 210-212 | NN | denotes | S2 |
| T69246 | 213-219 | NN | denotes | domain |
| T76095 | 219-220 | -COMMA- | denotes | , |
| T33023 | 221-225 | JJ | denotes | such |
| T94778 | 226-228 | IN | denotes | as |
| T12698 | 229-232 | DT | denotes | the |
| T82633 | 233-239 | NN | denotes | fusion |
| T75213 | 240-247 | NN | denotes | peptide |
| T29294 | 247-248 | -COMMA- | denotes | , |
| T28968 | 249-255 | NN | denotes | heptad |
| T29760 | 256-262 | NN | denotes | repeat |
| T53742 | 263-266 | CD | denotes | one |
| T18725 | 266-267 | -COMMA- | denotes | , |
| T43420 | 268-271 | CC | denotes | and |
| T34460 | 272-275 | DT | denotes | the |
| T26621 | 276-283 | JJ | denotes | central |
| T91466 | 284-289 | NN | denotes | helix |
| T93319 | 290-297 | NNS | denotes | domains |
| T88231 | 297-298 | -COMMA- | denotes | , |
| T49934 | 299-304 | WDT | denotes | which |
| T23715 | 305-308 | VBP | denotes | are |
| T33407 | 309-315 | RB | denotes | likely |
| T88882 | 316-323 | JJ | denotes | subject |
| T76117 | 324-326 | TO | denotes | to |
| T4874 | 327-334 | JJR | denotes | greater |
| T38302 | 335-345 | JJ | denotes | functional |
| T99472 | 346-357 | NNS | denotes | constraints |
| T34520 | 358-359 | -LRB- | denotes | ( |
| T48991 | 359-366 | NN | denotes | Fig. 4a |
| T5319 | 366-367 | -RRB- | denotes | ) |
| R54626 | T39186 | T18701 | arg1Of | found,Firstly |
| R55552 | T39186 | T74266 | arg1Of | found,"," |
| R48506 | T36827 | T39186 | arg1Of | we,found |
| R85227 | T93591 | T39186 | arg2Of | elevated,found |
| R94248 | T93591 | T6773 | arg1Of | elevated,that |
| R56819 | T54008 | T13224 | arg1Of | diversity,amino-acid |
| R12367 | T54008 | T35302 | arg1Of | diversity,was |
| R36961 | T93591 | T35302 | arg2Of | elevated,was |
| R67157 | T54008 | T93591 | arg2Of | diversity,elevated |
| R98710 | T93591 | T90961 | arg1Of | elevated,at |
| R55146 | T86793 | T90961 | arg2Of | epitopes,at |
| R5883 | T86793 | T69090 | arg2Of | epitopes,known |
| R17754 | T32200 | T61088 | arg1Of | antibodies,targeted |
| R9367 | T86793 | T61088 | arg2Of | epitopes,targeted |
| R83504 | T32200 | T53019 | arg2Of | antibodies,by |
| R74212 | T32200 | T30461 | arg1Of | antibodies,neutralizing |
| R10411 | T32200 | T83554 | arg1Of | antibodies,"," |
| R98281 | T51281 | T32640 | arg1Of | as,such |
| R81049 | T32200 | T51281 | arg1Of | antibodies,as |
| R6966 | T58919 | T51281 | arg2Of | and,as |
| R21530 | T49099 | T69890 | arg1Of | domain,the |
| R64448 | T49099 | T83248 | arg1Of | domain,N-terminal |
| R49770 | T49099 | T58919 | arg1Of | domain,and |
| R65608 | T60790 | T58919 | arg2Of | domains,and |
| R95057 | T60790 | T18721 | arg1Of | domains,the |
| R69352 | T60790 | T18570 | arg1Of | domains,receptor-binding |
| R16170 | T96660 | T18812 | arg1Of | and,"," |
| R74990 | T61088 | T96660 | arg1Of | targeted,and |
| R8726 | T11216 | T96660 | arg2Of | reduced,and |
| R71690 | T86793 | T11216 | arg2Of | epitopes,reduced |
| R89891 | T11216 | T27277 | arg1Of | reduced,in |
| R47563 | T7777 | T27277 | arg2Of | regions,in |
| R49965 | T7777 | T89562 | arg1Of | regions,the |
| R85283 | T7777 | T23472 | arg1Of | regions,in |
| R56401 | T69246 | T23472 | arg2Of | domain,in |
| R32729 | T69246 | T66095 | arg1Of | domain,the |
| R3287 | T69246 | T52990 | arg1Of | domain,S2 |
| R10516 | T86793 | T76095 | arg1Of | epitopes,"," |
| R16608 | T94778 | T33023 | arg1Of | as,such |
| R96223 | T86793 | T94778 | arg1Of | epitopes,as |
| R16738 | T43420 | T94778 | arg2Of | and,as |
| R3992 | T75213 | T12698 | arg1Of | peptide,the |
| R20067 | T75213 | T82633 | arg1Of | peptide,fusion |
| R62161 | T75213 | T29294 | arg1Of | peptide,"," |
| R83184 | T29760 | T29294 | arg2Of | repeat,"," |
| R27719 | T29760 | T28968 | arg1Of | repeat,heptad |
| R49150 | T29760 | T53742 | arg1Of | repeat,one |
| R38048 | T43420 | T18725 | arg1Of | and,"," |
| R84039 | T75213 | T43420 | arg1Of | peptide,and |
| R65597 | T93319 | T43420 | arg2Of | domains,and |
| R93652 | T93319 | T34460 | arg1Of | domains,the |
| R84393 | T93319 | T26621 | arg1Of | domains,central |
| R23746 | T93319 | T91466 | arg1Of | domains,helix |
| R18674 | T93319 | T88231 | arg1Of | domains,"," |
| R28527 | T93319 | T49934 | arg1Of | domains,which |
| R95251 | T93319 | T23715 | arg1Of | domains,are |
| R68137 | T88882 | T23715 | arg2Of | subject,are |
| R82494 | T88882 | T33407 | arg1Of | subject,likely |
| R84782 | T93319 | T88882 | arg1Of | domains,subject |
| R15085 | T88882 | T76117 | arg1Of | subject,to |
| R84300 | T99472 | T76117 | arg2Of | constraints,to |
| R3107 | T99472 | T4874 | arg1Of | constraints,greater |
| R96110 | T99472 | T38302 | arg1Of | constraints,functional |
| R31642 | T99472 | T34520 | arg1Of | constraints,( |
| R75726 | T48991 | T34520 | arg2Of | Fig. 4a,( |
| R85323 | T5319 | T34520 | arg3Of | ),( |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T90 | 23-33 | Body_part | denotes | amino-acid | http://purl.org/sig/ont/fma/fma82739 |
| T91 | 284-289 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T126 | 23-28 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T127 | 240-247 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T89 | 0-368 | Sentence | denotes | Firstly, we found that amino-acid diversity was elevated at known epitopes targeted by neutralizing antibodies, such as the N-terminal domain and the receptor-binding domains, and reduced in the regions in the S2 domain, such as the fusion peptide, heptad repeat one, and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a). |
LitCovid-sample-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T4 | 284-289 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T89 | 0-368 | Sentence | denotes | Firstly, we found that amino-acid diversity was elevated at known epitopes targeted by neutralizing antibodies, such as the N-terminal domain and the receptor-binding domains, and reduced in the regions in the S2 domain, such as the fusion peptide, heptad repeat one, and the central helix domains, which are likely subject to greater functional constraints (Fig. 4a). |