PMC:7253482 / 1491-2299
Annnotations
LitCovid-PubTator
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LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T10","span":{"begin":700,"end":708},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T6","span":{"begin":70,"end":91},"obj":"Disease"},{"id":"T7","span":{"begin":223,"end":256},"obj":"Disease"},{"id":"T8","span":{"begin":270,"end":278},"obj":"Disease"},{"id":"T9","span":{"begin":270,"end":274},"obj":"Disease"},{"id":"T10","span":{"begin":377,"end":385},"obj":"Disease"},{"id":"T11","span":{"begin":377,"end":381},"obj":"Disease"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005087"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8","span":{"begin":147,"end":148},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T9","span":{"begin":178,"end":183},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T10","span":{"begin":521,"end":527},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T11","span":{"begin":677,"end":682},"obj":"http://purl.obolibrary.org/obo/CLO_0009985"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T10","span":{"begin":700,"end":708},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-PD-IDO
{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T6","span":{"begin":35,"end":44},"obj":"http://purl.obolibrary.org/obo/IDO_0000528"},{"id":"T7","span":{"begin":82,"end":91},"obj":"http://purl.obolibrary.org/obo/OGMS_0000045"},{"id":"T8","span":{"begin":630,"end":639},"obj":"http://purl.obolibrary.org/obo/IDO_0000528"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-Enju
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(CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-PD-FMA
{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T10","span":{"begin":700,"end":708},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-CHEBI
{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T10","span":{"begin":700,"end":708},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-PD-NCBITaxon
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LitCovid-sample-sentences
{"project":"LitCovid-sample-sentences","denotations":[{"id":"T12","span":{"begin":0,"end":123},"obj":"Sentence"},{"id":"T13","span":{"begin":124,"end":389},"obj":"Sentence"},{"id":"T14","span":{"begin":390,"end":640},"obj":"Sentence"},{"id":"T15","span":{"begin":641,"end":808},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-PD-MONDO
{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T6","span":{"begin":70,"end":91},"obj":"Disease"},{"id":"T7","span":{"begin":223,"end":256},"obj":"Disease"},{"id":"T8","span":{"begin":270,"end":278},"obj":"Disease"},{"id":"T9","span":{"begin":270,"end":274},"obj":"Disease"},{"id":"T10","span":{"begin":377,"end":385},"obj":"Disease"},{"id":"T11","span":{"begin":377,"end":381},"obj":"Disease"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005087"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-Pubtator
{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"78","span":{"begin":70,"end":91},"obj":"Disease"},{"id":"70","span":{"begin":115,"end":121},"obj":"Species"},{"id":"71","span":{"begin":132,"end":136},"obj":"Species"},{"id":"72","span":{"begin":178,"end":183},"obj":"Species"},{"id":"73","span":{"begin":223,"end":268},"obj":"Species"},{"id":"74","span":{"begin":270,"end":278},"obj":"Species"},{"id":"75","span":{"begin":290,"end":345},"obj":"Species"},{"id":"76","span":{"begin":377,"end":387},"obj":"Species"},{"id":"79","span":{"begin":402,"end":411},"obj":"Disease"},{"id":"77","span":{"begin":521,"end":527},"obj":"Species"},{"id":"67","span":{"begin":690,"end":695},"obj":"Gene"}],"attributes":[{"id":"A71","pred":"pubann:denotes","subj":"71","obj":"Tax:11118"},{"id":"A73","pred":"pubann:denotes","subj":"73","obj":"Tax:694009"},{"id":"A79","pred":"pubann:denotes","subj":"79","obj":"MESH:D003643"},{"id":"A70","pred":"pubann:denotes","subj":"70","obj":"Tax:9606"},{"id":"A72","pred":"pubann:denotes","subj":"72","obj":"Tax:9606"},{"id":"A76","pred":"pubann:denotes","subj":"76","obj":"Tax:2697049"},{"id":"A78","pred":"pubann:denotes","subj":"78","obj":"MESH:D012131"},{"id":"A75","pred":"pubann:denotes","subj":"75","obj":"Tax:1335626"},{"id":"A67","pred":"pubann:denotes","subj":"67","obj":"Gene:43740568"},{"id":"A74","pred":"pubann:denotes","subj":"74","obj":"Tax:694009"},{"id":"A77","pred":"pubann:denotes","subj":"77","obj":"Tax:9606"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sample-UniProt
{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T714","span":{"begin":696,"end":708},"obj":"Protein"}],"attributes":[{"id":"A714","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UIP0"},{"id":"A715","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UIN9"},{"id":"A716","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UIN8"},{"id":"A717","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UIN7"},{"id":"A718","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UIN6"},{"id":"A719","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9UBH8"},{"id":"A720","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NRH8"},{"id":"A721","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NRH7"},{"id":"A722","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NRH6"},{"id":"A723","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NRH5"},{"id":"A724","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NRH4"},{"id":"A725","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NPG5"},{"id":"A726","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NPE0"},{"id":"A727","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q9NP52"},{"id":"A728","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q95IF9"},{"id":"A729","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q8N5P3"},{"id":"A730","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q8IZU6"},{"id":"A731","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q8IZU5"},{"id":"A732","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q8IZU4"},{"id":"A733","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q86Z04"},{"id":"A734","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q7YR44"},{"id":"A735","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q7LA71"},{"id":"A736","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q7LA70"},{"id":"A737","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q5STD2"},{"id":"A738","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q5SQ85"},{"id":"A739","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q1XI16"},{"id":"A740","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q1XI12"},{"id":"A741","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/Q15517"},{"id":"A742","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/O43509"},{"id":"A743","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/O19084"},{"id":"A744","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/B0UYZ7"},{"id":"A745","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/B0S7V2"},{"id":"A746","pred":"uniprot_id","subj":"T714","obj":"https://www.uniprot.org/uniprot/A5A6L9"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T12","span":{"begin":0,"end":123},"obj":"Sentence"},{"id":"T13","span":{"begin":124,"end":389},"obj":"Sentence"},{"id":"T14","span":{"begin":390,"end":640},"obj":"Sentence"},{"id":"T15","span":{"begin":641,"end":808},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Coronaviruses (CoVs) are enveloped pathogens responsible for multiple respiratory disorders of varying severity in humans1. Certain CoVs represent a significant threat to global human health, as illustrated by outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) in 20032, Middle East respiratory syndrome coronavirus (MERS-CoV) in 20123, and most recently of SARS-CoV-24. Given their mortality rates, the current lack of targeted treatments and licensed vaccines, and their capacity to transmit between humans and across species barriers5,6, there is an urgent need for effective countermeasures to combat these pathogens. Ongoing vaccine development efforts focus on the spike (S) proteins that protrude from the viral envelope and constitute the main target of neutralizing antibodies7,8."}