PMC:7253233 / 6377-8341
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 223 | 1884-1891 | Species | denotes | red box | Tax:1226038 |
| 244 | 1390-1408 | Gene | denotes | C-reactive protein | Gene:1401 |
| 245 | 1249-1259 | Gene | denotes | fibrinogen | Gene:2244 |
| 246 | 30-37 | Species | denotes | patient | Tax:9606 |
| 247 | 1627-1634 | Species | denotes | patient | Tax:9606 |
| 248 | 401-414 | Chemical | denotes | Levetiracetam | MESH:D000077287 |
| 249 | 529-539 | Chemical | denotes | Vancomycin | MESH:D014640 |
| 250 | 541-550 | Chemical | denotes | Meropenem | MESH:D000077731 |
| 251 | 556-565 | Chemical | denotes | Acyclovir | MESH:D000212 |
| 252 | 118-132 | Disease | denotes | encephalopathy | MESH:D001927 |
| 253 | 198-208 | Disease | denotes | drowsiness | MESH:D006970 |
| 254 | 305-313 | Disease | denotes | seizures | MESH:D012640 |
| 255 | 466-473 | Disease | denotes | seizure | MESH:D012640 |
| 256 | 678-707 | Disease | denotes | white matter hyperintensities | MESH:D056784 |
| 257 | 770-793 | Disease | denotes | venous sinus thrombosis | MESH:D012851 |
| 258 | 799-817 | Disease | denotes | C5–C6 myelomalacia | MESH:C537005 |
| 259 | 894-903 | Disease | denotes | infection | MESH:D007239 |
| 260 | 948-954 | Disease | denotes | fevers | MESH:D005334 |
| 261 | 1115-1123 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 262 | 1177-1185 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 263 | 1657-1669 | Disease | denotes | tracheostomy |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T30 | 67-87 | Body_part | denotes | left upper extremity | http://purl.org/sig/ont/fma/fma7186 |
| T31 | 570-573 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T32 | 595-600 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T33 | 605-619 | Body_part | denotes | cervical spine | http://purl.org/sig/ont/fma/fma24138 |
| T34 | 678-690 | Body_part | denotes | white matter | http://purl.org/sig/ont/fma/fma83929 |
| T35 | 745-754 | Body_part | denotes | meningeal | http://purl.org/sig/ont/fma/fma231572 |
| T36 | 1401-1408 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T37 | 1520-1536 | Body_part | denotes | White blood cell | http://purl.org/sig/ont/fma/fma62852 |
| T38 | 1532-1536 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T39 | 1591-1599 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
| T40 | 1869-1875 | Body_part | denotes | vertex | http://purl.org/sig/ont/fma/fma46484 |
| T41 | 1934-1942 | Body_part | denotes | left arm | http://purl.org/sig/ont/fma/fma24896 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T27 | 595-600 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T28 | 678-690 | Body_part | denotes | white matter | http://purl.obolibrary.org/obo/UBERON_0002316 |
| T29 | 770-782 | Body_part | denotes | venous sinus | http://purl.obolibrary.org/obo/UBERON_0006615 |
| T30 | 1526-1531 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T31 | 1939-1942 | Body_part | denotes | arm | http://purl.obolibrary.org/obo/UBERON_0001460 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T64 | 118-132 | Disease | denotes | encephalopathy | http://purl.obolibrary.org/obo/MONDO_0005560 |
| T65 | 783-793 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T66 | 894-903 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T67 | 1115-1123 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T68 | 1177-1185 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T70 | 78-87 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremity |
| T71 | 95-103 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T72 | 474-482 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T73 | 595-600 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
| T74 | 595-600 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
| T75 | 799-801 | http://purl.obolibrary.org/obo/CLO_0002131 | denotes | C5 |
| T76 | 802-804 | http://purl.obolibrary.org/obo/CLO_0002140 | denotes | C6 |
| T77 | 802-804 | http://purl.obolibrary.org/obo/CLO_0051387 | denotes | C6 |
| T78 | 802-804 | http://purl.obolibrary.org/obo/CLO_0051684 | denotes | C6 |
| T79 | 802-804 | http://purl.obolibrary.org/obo/CLO_0051685 | denotes | C6 |
| T80 | 802-804 | http://purl.obolibrary.org/obo/CLO_0051686 | denotes | C6 |
| T81 | 1038-1039 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T82 | 1103-1110 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T83 | 1186-1197 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing was |
| T84 | 1526-1531 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T85 | 1532-1536 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T86 | 1655-1656 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T87 | 1718-1719 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T88 | 1939-1942 | http://www.ebi.ac.uk/efo/EFO_0001410 | denotes | arm |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T11 | 278-281 | Chemical | denotes | EEG | http://purl.obolibrary.org/obo/CHEBI_73494 |
| T12 | 401-414 | Chemical | denotes | Levetiracetam | http://purl.obolibrary.org/obo/CHEBI_6437 |
| T13 | 529-539 | Chemical | denotes | Vancomycin | http://purl.obolibrary.org/obo/CHEBI_28001 |
| T14 | 541-550 | Chemical | denotes | Meropenem | http://purl.obolibrary.org/obo/CHEBI_43968 |
| T15 | 1401-1408 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T16 | 1497-1510 | Chemical | denotes | antimicrobial | http://purl.obolibrary.org/obo/CHEBI_33281 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T44 | 118-132 | Phenotype | denotes | encephalopathy | http://purl.obolibrary.org/obo/HP_0001298 |
| T45 | 198-208 | Phenotype | denotes | drowsiness | http://purl.obolibrary.org/obo/HP_0002329 |
| T46 | 299-313 | Phenotype | denotes | focal seizures | http://purl.obolibrary.org/obo/HP_0007359 |
| T47 | 466-473 | Phenotype | denotes | seizure | http://purl.obolibrary.org/obo/HP_0001250 |
| T48 | 678-707 | Phenotype | denotes | white matter hyperintensities | http://purl.obolibrary.org/obo/HP_0030890 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T52 | 0-242 | Sentence | denotes | On postoperative day two, the patient suffered several episodes of left upper extremity clonic activity and worsening encephalopathy with decline in level of consciousness as evidenced by increased drowsiness and inability to follow commands. |
| T53 | 243-400 | Sentence | denotes | Continuous electroencephalography (EEG) confirmed three focal seizures lasting approximately 30 s each arising from the right centroparietal region (Fig. 2). |
| T54 | 401-492 | Sentence | denotes | Levetiracetam was initiated and both clinical and electrographic seizure activity subsided. |
| T55 | 493-583 | Sentence | denotes | Antibiotic regimen was broadened to Vancomycin, Meropenem, and Acyclovir for CSF coverage. |
| T56 | 584-832 | Sentence | denotes | MRI of the brain and cervical spine with and without contrast was remarkable only for chronic white matter hyperintensities, without acute intracranial lesions, meningeal enhancement or venous sinus thrombosis, and C5–C6 myelomalacia, respectively. |
| T57 | 833-919 | Sentence | denotes | Lumbar puncture was not performed due to the risk of seeding infection into neuroaxis. |
| T58 | 920-1244 | Sentence | denotes | Given persistent high-grade fevers, worsening respiratory status requiring intubation, and recent possible exposures, a respiratory viral panel was sent in addition to separate rapid testing for COVID-19 polymerase chain reaction on postoperative day 4 and COVID-19 testing was confirmed as positive twenty-four hours later. |
| T59 | 1245-1389 | Sentence | denotes | His fibrinogen level was elevated at 631 mg/dL (normal range 200–400 mg/dL) and continued to increase to over 860 mg/dL over the following days. |
| T60 | 1390-1519 | Sentence | denotes | C-reactive protein increased from 1.7 mg/dL on prior admission to 27.3 mg/dL and remained elevated despite antimicrobial therapy. |
| T61 | 1520-1622 | Sentence | denotes | White blood cell count steadily improved over his hospitalization, and platelet count remained stable. |
| T62 | 1623-1784 | Sentence | denotes | Our patient ultimately received a tracheostomy and after 30 days of ICU stay was discharged to a long-term acute care hospital for further ventilator management. |
| T63 | 1785-1815 | Sentence | denotes | Fig. 2 Electroencephalography. |
| T64 | 1816-1964 | Sentence | denotes | Rhythmic discharges noted in the right frontocentral/vertex region (red box) corresponding to clonic movements of the left arm (Color figure online) |