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PMC:7253233 / 11657-13037 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
401 0-5 Species denotes Human Tax:9606
402 6-19 Species denotes coronaviruses Tax:11118
403 59-64 Species denotes human Tax:9606
404 162-167 Species denotes human Tax:9606
405 446-456 Species denotes SARS-Cov-2 Tax:2697049
406 588-596 Species denotes patients Tax:9606
407 695-700 Species denotes human Tax:9606
408 701-714 Species denotes coronaviruses Tax:11118
409 716-719 Species denotes CoV Tax:11118
410 726-731 Species denotes CoV-2 Tax:2697049
411 963-971 Species denotes patients Tax:9606
412 1193-1203 Species denotes SARS-CoV-2 Tax:2697049
413 1313-1321 Species denotes patients Tax:9606
414 270-290 Disease denotes SARS-CoV-1 infection MESH:C000657245
415 563-584 Disease denotes neurological symptoms MESH:D009422
416 602-610 Disease denotes COVID-19 MESH:C000657245
417 792-800 Disease denotes seizures MESH:D012640
418 899-915 Disease denotes systemic disease MESH:D034721
419 984-992 Disease denotes COVID-19 MESH:C000657245
420 1325-1333 Disease denotes seizures MESH:D012640
421 1351-1372 Disease denotes neurological diseases MESH:D020271

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T58 65-75 Body_part denotes astrocytes http://purl.org/sig/ont/fma/fma54537
T59 80-89 Body_part denotes microglia http://purl.org/sig/ont/fma/fma68923
T60 93-104 Body_part denotes neural cell http://purl.org/sig/ont/fma/fma70333
T61 100-104 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T62 144-147 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T63 168-173 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T64 296-299 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T65 367-372 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T66 373-379 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T67 501-520 Body_part denotes cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T68 522-525 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T69 929-932 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T70 1027-1032 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T71 1033-1038 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T72 1258-1264 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T73 1293-1297 Body_part denotes glia http://purl.org/sig/ont/fma/fma54541

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T45 168-173 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T46 296-299 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T47 367-372 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T48 373-379 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T49 501-520 Body_part denotes cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359
T50 929-932 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T51 1027-1046 Body_part denotes blood–brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T52 1027-1032 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T53 1033-1038 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T54 1258-1264 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T101 270-278 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 281-290 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 320-324 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T104 446-450 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T105 602-610 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 899-915 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T107 984-992 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T108 1133-1148 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T109 1193-1201 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T110 1351-1372 Disease denotes neurological diseases http://purl.obolibrary.org/obo/MONDO_0005071

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T131 0-5 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T132 59-64 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T133 65-75 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocytes
T134 80-89 http://purl.obolibrary.org/obo/CL_0000129 denotes microglia
T135 100-104 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T136 151-152 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 162-167 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T138 168-173 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T139 168-173 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T140 253-254 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T141 296-299 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T142 296-299 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T143 296-299 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T144 352-357 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 365-366 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 367-372 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T147 367-372 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T148 422-423 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T149 457-460 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T150 695-700 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T151 822-823 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 859-864 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T153 875-876 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T154 929-932 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T155 929-932 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T156 929-932 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T157 1027-1032 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T158 1027-1032 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T159 1033-1038 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T160 1033-1038 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T161 1052-1057 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T162 1131-1132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T78 780-800 Phenotype denotes symptomatic seizures http://purl.obolibrary.org/obo/HP_0011145
T79 1325-1333 Phenotype denotes seizures http://purl.obolibrary.org/obo/HP_0001250

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T91 0-252 Sentence denotes Human coronaviruses (HCoV) have been established to infect human astrocytes and microglia in neural cell cultures as well as detection of viral RNA in a study of human brain autopsy samples supporting their neurotropic and neuroinvasive properties [5].
T92 253-393 Sentence denotes A case report of SARS-CoV-1 infection with CNS symptoms during the SARS epidemic also isolated the virus within a brain tissue specimen [6].
T93 394-773 Sentence denotes Although direct evidence of a neurotropic effect of SARS-Cov-2 has not been reported as yet through either cerebrospinal fluid (CSF) or autopsy studies, the presence of neurological symptoms in patients with COVID-19 disease during this current pandemic, and the similarity between the two strains of human coronaviruses (CoV-1 and CoV-2), makes this mechanism highly suggestive.
T94 774-1001 Sentence denotes Acute symptomatic seizures may be the result of a possible neurotropic effect of the virus or can be a marker of severity of systemic disease itself since CNS symptoms were found mainly in patients with severe COVID-19 disease.
T95 1002-1155 Sentence denotes After penetration of the blood–brain barrier, the virus can slow the cerebral microcirculation, possibly through the creation of a hypercoagulable state.
T96 1156-1269 Sentence denotes This allows increased interaction of SARS-CoV-2 with the endothelial receptors and receptors on glial tissue [7].
T97 1270-1380 Sentence denotes The interaction at the glia may predispose patients to seizures as seen in other neurological diseases [8, 9].

2_test

Id Subject Object Predicate Lexical cue
32462412-10982334-75539779 249-250 10982334 denotes 5
32462412-16163626-75539780 390-391 16163626 denotes 6
32462412-32167747-75539781 1266-1267 32167747 denotes 7
32462412-18336559-75539782 1377-1378 18336559 denotes 9