PMC:7253233 / 1115-2089
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
72 | 0-8 | Species | denotes | Patients | Tax:9606 |
73 | 320-328 | Species | denotes | patients | Tax:9606 |
74 | 548-556 | Species | denotes | patients | Tax:9606 |
75 | 747-755 | Species | denotes | patients | Tax:9606 |
76 | 920-938 | Species | denotes | SARS-Coronavirus-2 | Tax:2697049 |
77 | 14-22 | Disease | denotes | COVID-19 | MESH:C000657245 |
78 | 59-67 | Disease | denotes | seizures | MESH:D012640 |
79 | 96-104 | Disease | denotes | seizures | MESH:D012640 |
80 | 148-156 | Disease | denotes | seizures | MESH:D012640 |
81 | 375-383 | Disease | denotes | seizures | MESH:D012640 |
82 | 434-454 | Disease | denotes | acute encephalopathy | MESH:D001927 |
83 | 513-534 | Disease | denotes | neurological symptoms | MESH:D009422 |
84 | 576-584 | Disease | denotes | COVID-19 | MESH:C000657245 |
85 | 649-662 | Disease | denotes | organ failure | MESH:D009102 |
86 | 683-730 | Disease | denotes | intravascular coagulopathy-related brain injury | MESH:D004211 |
87 | 899-916 | Disease | denotes | neuroinvasiveness |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T4 | 649-654 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
T5 | 718-723 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
T6 | 799-804 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
T7 | 805-810 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
T8 | 852-860 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T5 | 649-654 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
T6 | 718-723 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
T7 | 799-818 | Body_part | denotes | blood–brain barrier | http://purl.obolibrary.org/obo/UBERON_0000120 |
T8 | 799-804 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
T9 | 805-810 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T14 | 14-22 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T15 | 440-454 | Disease | denotes | encephalopathy | http://purl.obolibrary.org/obo/MONDO_0005560 |
T16 | 576-584 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 636-662 | Disease | denotes | multi-system organ failure | http://purl.obolibrary.org/obo/MONDO_0043726 |
T18 | 697-709 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
T19 | 718-730 | Disease | denotes | brain injury | http://purl.obolibrary.org/obo/MONDO_0043510 |
T20 | 724-730 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T21 | 920-924 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15 | 649-654 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
T16 | 718-723 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
T17 | 718-723 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
T18 | 799-804 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T19 | 799-804 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
T20 | 805-810 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
T21 | 805-810 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T4 | 240-249 | Chemical | denotes | sedatives | http://purl.obolibrary.org/obo/CHEBI_35717 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 782-791 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | breakdown |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T9 | 59-67 | Phenotype | denotes | seizures | http://purl.obolibrary.org/obo/HP_0001250 |
T10 | 96-104 | Phenotype | denotes | seizures | http://purl.obolibrary.org/obo/HP_0001250 |
T11 | 140-156 | Phenotype | denotes | (motor) seizures | http://purl.obolibrary.org/obo/HP_0020219 |
T12 | 375-383 | Phenotype | denotes | seizures | http://purl.obolibrary.org/obo/HP_0001250 |
T13 | 434-454 | Phenotype | denotes | acute encephalopathy | http://purl.obolibrary.org/obo/HP_0006846 |
T14 | 697-709 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15 | 0-130 | Sentence | denotes | Patients with COVID-19 disease are at an elevated risk for seizures, and the mechanism of these seizures is likely multifactorial. |
T16 | 131-305 | Sentence | denotes | Clinical (motor) seizures may not be readily detected in this population due to the expansive utilization of sedatives and paralytics for respiratory optimization strategies. |
T17 | 306-492 | Sentence | denotes | Many of these patients are also not electrographically monitored for seizures due to limited resources, multifactorial risk for acute encephalopathy, and the risk of cross-contamination. |
T18 | 493-731 | Sentence | denotes | Previously, several neurological symptoms were seen in patients with more advanced COVID-19 disease, and these were thought to be secondary to multi-system organ failure and/or disseminated intravascular coagulopathy-related brain injury. |
T19 | 732-871 | Sentence | denotes | However, these patients may also have an advanced breakdown of the blood–brain barrier precipitated by pro-inflammatory cytokine reactions. |
T20 | 872-974 | Sentence | denotes | The neurotropic effect and neuroinvasiveness of SARS-Coronavirus-2 have not been directly established. |