PMC:7252096 / 102220-126093 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T21 59-63 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T22 68-73 Body_part denotes Ileum http://purl.org/sig/ont/fma/fma7208
T23 131-138 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T24 227-233 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T25 669-674 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T26 786-791 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T27 856-861 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T28 1080-1084 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T29 1341-1346 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T30 1589-1593 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T31 1616-1620 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T32 1856-1861 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T33 1896-1907 Body_part denotes Pneumocytes http://purl.org/sig/ont/fma/fma62499
T34 2019-2035 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T35 2030-2035 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T36 2040-2051 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T37 2230-2234 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T38 2235-2241 Body_part denotes Tissue http://purl.org/sig/ont/fma/fma9637
T39 2348-2354 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T40 2783-2787 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T41 2798-2802 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T42 3145-3149 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T43 3172-3177 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T44 3250-3255 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T45 3305-3309 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T46 3404-3408 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T47 3573-3578 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T48 3594-3598 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T49 3692-3697 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T50 3714-3719 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 3720-3728 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T52 3739-3744 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T53 3769-3782 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T54 3777-3782 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T55 3822-3834 Body_part denotes cell cluster http://purl.org/sig/ont/fma/fma62807
T56 3822-3826 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T57 3913-3924 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T58 4065-4081 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T59 4076-4081 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T60 4260-4265 Body_part denotes Ileum http://purl.org/sig/ont/fma/fma7208
T61 4494-4499 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T62 4624-4628 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T63 4827-4831 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T64 4939-4943 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T65 5396-5401 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T66 5538-5542 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T67 5620-5636 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T68 5631-5636 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T69 5738-5754 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T70 5749-5754 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 5939-5951 Body_part denotes Nasal Mucosa http://purl.org/sig/ont/fma/fma59684
T72 5945-5951 Body_part denotes Mucosa http://purl.org/sig/ont/fma/fma85355
T73 6068-6072 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T74 6123-6125 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T76 6243-6247 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T77 6251-6255 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T78 6645-6654 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T79 6678-6694 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T80 6689-6694 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T81 6720-6724 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T82 6905-6911 Body_part denotes Tissue http://purl.org/sig/ont/fma/fma9637
T83 7016-7023 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T84 7178-7184 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T85 7337-7341 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T86 7427-7442 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T87 7438-7442 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T88 7486-7497 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T89 7510-7521 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T90 7590-7595 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T91 7606-7611 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T92 7627-7631 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T93 7657-7662 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T94 7731-7735 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T95 7825-7841 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T96 7836-7841 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T97 8014-8024 Body_part denotes Basal Cell http://purl.org/sig/ont/fma/fma62516
T98 8020-8024 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T99 8025-8033 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T100 8167-8173 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T101 8924-8936 Body_part denotes Nasal Mucosa http://purl.org/sig/ont/fma/fma59684
T102 8930-8936 Body_part denotes Mucosa http://purl.org/sig/ont/fma/fma85355
T103 9132-9138 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T104 9427-9432 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T105 9603-9608 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T106 9718-9723 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 9843-9848 Body_part denotes elbow http://purl.org/sig/ont/fma/fma24901
T108 10215-10220 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 10467-10472 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T110 10500-10504 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T111 10751-10756 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T112 11034-11038 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T113 11150-11156 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T114 11310-11316 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T115 11351-11356 Body_part denotes joint http://purl.org/sig/ont/fma/fma7490
T116 11357-11363 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T117 11918-11921 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T118 12075-12079 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T119 12084-12088 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T120 12372-12377 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T121 12549-12560 Body_part denotes Pneumocytes http://purl.org/sig/ont/fma/fma62499
T122 12687-12692 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T123 12694-12699 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T124 12937-12943 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T125 12968-12975 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T126 13528-13532 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T127 13583-13587 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T128 13609-13620 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T129 13680-13684 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T130 13732-13737 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T131 13749-13753 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T132 13757-13761 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T133 14023-14028 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T134 14086-14090 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T135 14142-14146 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T136 14233-14237 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T137 14600-14616 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T138 14611-14616 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 14618-14629 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T140 14631-14642 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T141 14647-14657 Body_part denotes leukocytes http://purl.org/sig/ont/fma/fma62852
T142 14663-14678 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T143 14674-14678 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T144 14695-14704 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T145 14838-14853 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T146 14849-14853 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T147 15043-15058 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T148 15054-15058 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T149 15102-15106 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T150 15253-15258 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T151 15346-15350 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T152 15379-15384 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T153 15810-15815 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 15972-15976 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T155 16329-16333 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T156 16377-16381 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T157 16396-16400 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T158 16651-16653 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T160 16753-16757 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T161 16841-16859 Body_part denotes inferior turbinate http://purl.org/sig/ont/fma/fma54736
T162 16905-16907 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T164 17067-17069 Body_part denotes v1 http://purl.org/sig/ont/fma/fma13444|http://purl.org/sig/ont/fma/fma68614
T166 17155-17159 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T167 17351-17355 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T168 17370-17374 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T169 17447-17452 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T170 17453-17458 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T171 17505-17509 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T172 17571-17575 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T173 17590-17595 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T174 17733-17737 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T175 17771-17775 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T176 17926-17930 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T177 18087-18092 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T178 18161-18165 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T179 18407-18412 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T180 18657-18661 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T181 18723-18730 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T182 18750-18755 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T183 18760-18764 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T184 18905-18910 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T185 18927-18931 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T186 19017-19022 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T187 19106-19110 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T188 19176-19180 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T189 19339-19345 Body_part denotes cell’s http://purl.org/sig/ont/fma/fma68646
T190 19640-19644 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T191 19776-19782 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T192 20045-20050 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T193 20059-20063 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T194 20121-20125 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T195 20134-20138 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T196 20219-20224 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T197 20295-20300 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T198 20370-20375 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T199 20428-20433 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T200 20521-20526 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T201 20527-20539 Body_part denotes cell cluster http://purl.org/sig/ont/fma/fma62807
T202 20527-20531 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T203 20573-20578 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T204 20618-20623 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T205 20642-20646 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T206 20647-20659 Body_part denotes cell cluster http://purl.org/sig/ont/fma/fma62807
T207 20647-20651 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T208 20693-20698 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T209 20833-20838 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T210 20848-20853 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T211 20869-20875 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T212 21017-21021 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T213 21022-21027 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T214 21073-21077 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T215 21078-21083 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T216 21129-21134 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T217 21135-21140 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T218 21186-21191 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T219 21192-21197 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T220 21233-21237 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T221 21256-21261 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T222 21280-21285 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T223 21298-21302 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T224 21587-21591 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T225 21632-21637 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T226 21735-21746 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T227 21871-21876 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T228 22080-22085 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T229 22139-22144 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T230 22191-22196 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T231 22372-22377 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T232 22431-22436 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T233 22571-22576 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T234 22810-22815 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T235 22890-22895 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T236 22972-22977 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T237 23157-23161 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T238 23780-23784 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T237 59-63 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T238 68-73 Body_part denotes Ileum http://purl.obolibrary.org/obo/UBERON_0002116
T239 536-541 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T240 2230-2234 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T241 2235-2241 Body_part denotes Tissue http://purl.obolibrary.org/obo/UBERON_0000479
T242 2628-2633 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T243 3594-3598 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T244 3822-3834 Body_part denotes cell cluster http://purl.obolibrary.org/obo/UBERON_0034922
T245 4260-4265 Body_part denotes Ileum http://purl.obolibrary.org/obo/UBERON_0002116
T246 5120-5125 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T247 5945-5951 Body_part denotes Mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T248 6905-6911 Body_part denotes Tissue http://purl.obolibrary.org/obo/UBERON_0000479
T249 8930-8936 Body_part denotes Mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T250 9403-9408 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T251 9843-9848 Body_part denotes elbow http://purl.obolibrary.org/obo/UBERON_0001461
T252 11034-11038 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T253 14674-14686 Body_part denotes cell cluster http://purl.obolibrary.org/obo/UBERON_0034922
T254 14849-14861 Body_part denotes cell cluster http://purl.obolibrary.org/obo/UBERON_0034922
T255 17447-17452 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T256 18750-18755 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T257 18760-18764 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T258 19776-19782 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T259 20045-20050 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T260 20121-20125 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T261 20521-20526 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T262 20527-20539 Body_part denotes cell cluster http://purl.obolibrary.org/obo/UBERON_0034922
T263 20618-20623 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T264 20642-20646 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T265 20647-20659 Body_part denotes cell cluster http://purl.obolibrary.org/obo/UBERON_0034922
T266 20757-20762 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T267 20869-20875 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T268 21017-21021 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T269 21073-21077 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T270 21129-21134 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T271 21186-21191 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T372 3699-3703 Disease denotes CD3D http://purl.obolibrary.org/obo/MONDO_0014280
T373 6474-6482 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T374 6483-6495 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T375 6931-6943 Disease denotes Tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T376 12790-12809 Disease denotes Influenza Infection http://purl.obolibrary.org/obo/MONDO_0005812
T377 12958-12967 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T378 14030-14039 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T379 15220-15229 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T380 15336-15345 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T37 45-50 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T38 51-58 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes Primate
T39 59-63 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T40 59-63 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T41 68-73 http://purl.obolibrary.org/obo/UBERON_0002116 denotes Ileum
T42 103-110 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T43 143-149 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T44 268-271 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T45 534-535 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 652-657 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T47 669-674 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T48 720-725 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T49 786-791 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 856-861 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T51 1080-1089 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T52 1110-1111 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 1341-1346 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T54 1589-1599 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T55 1616-1625 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T56 1668-1673 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T57 1701-1705 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T58 1842-1847 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T59 1856-1861 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T60 2019-2029 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T61 2030-2035 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T62 2224-2229 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T63 2230-2234 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T64 2230-2234 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T65 2626-2627 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T66 2757-2762 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T67 2779-2787 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T68 2798-2802 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T69 2948-2949 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T70 3094-3099 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T71 3145-3155 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T72 3170-3177 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T73 3250-3255 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T74 3305-3314 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T75 3385-3390 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T76 3404-3408 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T77 3573-3578 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T78 3588-3593 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T79 3594-3598 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T80 3594-3598 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T81 3690-3697 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T82 3712-3719 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T83 3739-3744 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T84 3777-3782 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T85 3810-3811 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 3822-3834 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cell cluster
T87 3955-3956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 3974-3978 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T89 4065-4075 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T90 4076-4081 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T91 4254-4259 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T92 4260-4265 http://purl.obolibrary.org/obo/UBERON_0002116 denotes Ileum
T93 4341-4343 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T94 4341-4343 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T95 4349-4350 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 4494-4499 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T97 4504-4509 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T98 4598-4603 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T99 4620-4628 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T100 4669-4670 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 4726-4731 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T102 4827-4831 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T103 4939-4949 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T104 5142-5143 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 5283-5288 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T106 5396-5401 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T107 5449-5454 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T108 5505-5509 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T109 5538-5547 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T110 5620-5630 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T111 5631-5636 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T112 5667-5668 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T113 5678-5682 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T114 5738-5748 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T115 5749-5754 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T116 5927-5932 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T117 5945-5951 http://purl.obolibrary.org/obo/UBERON_0000344 denotes Mucosa
T118 6042-6046 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T119 6068-6072 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T120 6215-6219 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T121 6243-6247 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T122 6251-6255 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T123 6296-6302 http://purl.obolibrary.org/obo/BFO_0000030 denotes object
T124 6665-6670 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T125 6671-6677 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T126 6678-6688 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T127 6689-6694 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T128 6720-6724 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T129 6769-6773 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T130 6988-6995 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T131 7024-7030 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T132 7070-7072 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T133 7070-7072 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T134 7330-7334 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T135 7337-7346 http://purl.obolibrary.org/obo/CL_0000000 denotes Cell type
T136 7347-7353 http://purl.obolibrary.org/obo/CLO_0007225 denotes labels
T137 7387-7392 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T138 7427-7437 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T139 7438-7442 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T140 7590-7595 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T141 7606-7611 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T142 7627-7631 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T143 7657-7662 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T144 7714-7718 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T145 7731-7735 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T146 7825-7835 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T147 7836-7841 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T148 8014-8024 http://purl.obolibrary.org/obo/CL_0000646 denotes Basal Cell
T149 8245-8247 http://purl.obolibrary.org/obo/CLO_0037161 denotes en
T150 8496-8503 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T151 8510-8511 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 8918-8923 http://purl.obolibrary.org/obo/CLO_0007836 denotes Mouse
T153 8930-8936 http://purl.obolibrary.org/obo/UBERON_0000344 denotes Mucosa
T154 8999-9004 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T155 9401-9402 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T156 9427-9432 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T157 9474-9479 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T158 9586-9591 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T159 9603-9608 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T160 9648-9653 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T161 9718-9723 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T162 9774-9775 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T163 9984-9985 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 10215-10220 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T165 10467-10472 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T166 10498-10499 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 10500-10509 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T168 10560-10565 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T169 10593-10597 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T170 10737-10742 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T171 10751-10756 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T172 11034-11038 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T173 11034-11038 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T174 11070-11074 http://purl.obolibrary.org/obo/CLO_0008825 denotes R KO
T175 11131-11132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T176 11200-11205 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T177 11206-11211 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T178 11222-11227 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T179 11304-11309 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T180 11351-11356 http://purl.obolibrary.org/obo/UBERON_0000982 denotes joint
T181 11351-11356 http://purl.obolibrary.org/obo/UBERON_0004905 denotes joint
T182 11505-11510 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T183 11601-11606 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T184 11874-11878 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T185 12071-12079 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T186 12084-12088 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T187 12131-12136 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T188 12250-12255 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T189 12272-12277 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T190 12347-12352 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T191 12372-12377 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T192 12471-12476 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T193 12655-12656 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 12687-12692 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T195 12694-12699 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T196 13163-13168 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T197 13478-13479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 13528-13532 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T199 13583-13587 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T200 13609-13620 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T201 13621-13626 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T202 13680-13684 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T203 13732-13737 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 13749-13753 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T205 13757-13761 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T206 13922-13927 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T207 13937-13938 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T208 14023-14028 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T209 14046-14051 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T210 14075-14080 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T211 14086-14090 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T212 14105-14110 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T213 14142-14146 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T214 14233-14242 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T215 14307-14312 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T216 14390-14393 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T217 14600-14610 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T218 14611-14616 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T219 14663-14673 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T220 14674-14686 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cell cluster
T221 14838-14848 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T222 14849-14861 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cell cluster
T223 14898-14903 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T224 15043-15053 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T225 15054-15058 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T226 15075-15078 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T227 15102-15106 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T228 15196-15201 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T229 15253-15258 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T230 15379-15384 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T231 15429-15430 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T232 15487-15488 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 15810-15828 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cells and clusters
T234 15972-15976 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T235 16347-16348 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 16392-16400 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T237 16405-16406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T238 16452-16455 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T239 16456-16457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T240 16753-16757 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T241 17155-17159 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T242 17366-17374 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T243 17376-17377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T244 17433-17438 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T245 17439-17446 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T246 17447-17452 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T247 17453-17458 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T248 17463-17464 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T249 17501-17509 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T250 17567-17575 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T251 17590-17595 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T252 17653-17654 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T253 17677-17679 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T254 17771-17775 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T255 17926-17930 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T256 18087-18092 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T257 18161-18165 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T258 18255-18256 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T259 18281-18282 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T260 18407-18412 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T261 18495-18496 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T262 18585-18586 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T263 18657-18661 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T264 18736-18741 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T265 18742-18749 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T266 18750-18755 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T267 18760-18764 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T268 18760-18764 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T269 18779-18780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T270 18905-18910 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T271 18927-18931 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T272 18973-18974 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T273 19017-19022 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T274 19106-19110 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T275 19160-19161 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T276 19174-19180 http://purl.obolibrary.org/obo/CLO_0001020 denotes a cell
T277 19196-19197 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T278 19339-19345 http://purl.obolibrary.org/obo/GO_0005623 denotes cell’s
T279 19376-19377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T280 19441-19442 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T281 19640-19644 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T282 19829-19834 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T283 20022-20023 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T284 20045-20050 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T285 20059-20063 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T286 20097-20098 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T287 20121-20125 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T288 20121-20125 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T289 20134-20138 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T290 20219-20224 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T291 20295-20300 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T292 20370-20375 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T293 20379-20380 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T294 20428-20433 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T295 20521-20526 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T296 20527-20539 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cell cluster
T297 20573-20578 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T298 20618-20623 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T299 20642-20646 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T300 20642-20646 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T301 20647-20659 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cell cluster
T302 20693-20698 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T303 20747-20748 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T304 20833-20838 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T305 20848-20853 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T306 20861-20862 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T307 20896-20897 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T308 21017-21021 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T309 21017-21021 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T310 21022-21027 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T311 21073-21077 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T312 21073-21077 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T313 21078-21083 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T314 21129-21134 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T315 21135-21140 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T316 21186-21191 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T317 21192-21197 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T318 21233-21237 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T319 21256-21261 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T320 21280-21285 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T321 21298-21307 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T322 21330-21332 http://purl.obolibrary.org/obo/CLO_0008935 denotes S9
T323 21587-21591 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T324 21632-21637 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T325 21641-21642 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 21713-21718 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T327 21719-21726 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T328 21856-21857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T329 21871-21876 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T330 21953-21954 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T331 22080-22085 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T332 22124-22125 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T333 22139-22144 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T334 22191-22196 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T335 22372-22377 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T336 22390-22391 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T337 22403-22404 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T338 22431-22452 http://purl.obolibrary.org/obo/UBERON_0034922 denotes cells in that cluster
T339 22571-22576 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T340 22580-22581 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T341 22697-22698 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T342 22810-22815 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T343 22890-22895 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T344 22928-22930 http://purl.obolibrary.org/obo/CLO_0008935 denotes S9
T345 22972-22977 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T346 22981-22982 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T347 23157-23161 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T348 23280-23287 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Testing
T349 23510-23513 http://purl.obolibrary.org/obo/CLO_0001547 denotes A p
T350 23582-23583 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T351 23646-23651 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T352 23744-23749 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T353 23780-23784 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T73454 1893-1895 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T1289 3219-3222 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T10711 3910-3912 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T62284 4341-4343 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T54385 5014-5017 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T25822 5341-5344 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T27564 7070-7072 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T67203 7483-7485 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T91028 8245-8247 Chemical denotes en http://purl.obolibrary.org/obo/CHEBI_30347
T39198 8286-8289 Chemical denotes TPM http://purl.obolibrary.org/obo/CHEBI_63631
T21041 11059-11061 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T49594 13628-13631 Chemical denotes HBA http://purl.obolibrary.org/obo/CHEBI_31585|http://purl.obolibrary.org/obo/CHEBI_5588
T75445 14053-14063 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T40879 16334-16342 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T78056 16382-16391 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T35798 16719-16727 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T3501 16783-16785 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T914 16921-16923 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T21728 16960-16962 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T55329 17086-17088 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T49729 17356-17365 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T70596 17491-17500 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T14582 17557-17566 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T92850 17738-17746 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T18549 18882-18891 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T76325 19205-19213 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T9827 19304-19313 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T1128 19908-19916 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T15833 19945-19954 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T17094 21732-21734 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T4 1315-1332 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptionally
T5 6483-6495 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T6 10189-10206 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptionally
T7 11546-11556 http://purl.obolibrary.org/obo/GO_0006351 denotes transcript
T8 12084-12094 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T9 13048-13057 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T10 14086-14096 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T11 14207-14214 http://purl.obolibrary.org/obo/GO_0140014 denotes mitosis
T12 14207-14214 http://purl.obolibrary.org/obo/GO_0000278 denotes mitosis
T13 15102-15117 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T14 15893-15914 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T15 15901-15914 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T16 16466-16479 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T17 17241-17254 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T18 17946-17959 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T19 18031-18041 http://purl.obolibrary.org/obo/GO_0006351 denotes transcript
T20 18115-18128 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T21 18571-18581 http://purl.obolibrary.org/obo/GO_0006351 denotes transcript
T22 23780-23795 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T739 0-39 Sentence denotes Quantification and Statistical Analysis
T740 41-73 Sentence denotes Non-Human Primate Lung and Ileum
T741 74-189 Sentence denotes Libraries corresponding to 7 animals (variable number of tissues per animal) were sequenced using Illumina NextSeq.
T742 190-385 Sentence denotes Reads were aligned to the M. mulatta genome assembly 8.0.1 annotation version 102 and processed according to the Drop-Seq Computational Protocol v2.0 (https://github.com/broadinstitute/Drop-seq).
T743 386-559 Sentence denotes Data was normalized and scaled using the Seurat R package v2.3.4 (https://satijalab.org/seurat/): transforming the data to loge(UMI+1) and applying a scale factor of 10,000.
T744 560-792 Sentence denotes To identify major axes of variation within our data, we first examined only highly variable genes across all cells, yielding approximately 1,000-3,000 variable genes with average expression > 0.1 log-normalized UMI across all cells.
T745 793-905 Sentence denotes An approximate principal component analysis was applied to the cells to generate 100 principal components (PCs).
T746 906-1054 Sentence denotes Using the JackStraw function within Seurat, we identified significant PCs to be used for subsequent clustering and further dimensionality reduction.
T747 1055-1290 Sentence denotes For 2D visualization and cell type clustering, we used a Uniform Manifold Approximation and Projection (UMAP) dimensionality reduction technique (https://github.com/lmcinnes/umap) with “min_dist” set to 0.5 and “n_neighbors” set to 30.
T748 1291-1531 Sentence denotes To identify clusters of transcriptionally similar cells, we employed unsupervised clustering as described above using the FindClusters tool within the Seurat R package with default parameters and k.param set to 10 and resolution set to 0.5.
T749 1532-1817 Sentence denotes Each cluster was sub-clustered to identify more granular cell types, requiring each cell type to express > 25 significantly upregulated genes by differential expression test (FindMarkers implemented in Seurat, setting “test.use” to “bimod,” Bonferroni-adjusted p value cutoff < 0.001).
T750 1818-1998 Sentence denotes Differential expression tests between cells from ACE2 + versus ACE2 - Type II Pneumocytes were conducted using the SCDE R package with default parameters (Kharchenko et al., 2014).
T751 1999-2222 Sentence denotes Expression data for epithelial cells and enterocytes included in this dataset can be visualized and downloaded here: https://singlecell.broadinstitute.org/single_cell/study/SCP807?scpbr=the-alexandria-project#study-summary.
T752 2224-2241 Sentence denotes Human Lung Tissue
T753 2242-2316 Sentence denotes Libraries corresponding to 8 donors were sequenced using Illumina NextSeq.
T754 2317-2477 Sentence denotes Reads were aligned to the hg19 genome assembly and processed according to the Drop-Seq Computational Protocol v2.0 (https://github.com/broadinstitute/Drop-seq).
T755 2478-2651 Sentence denotes Data was normalized and scaled using the Seurat R package v3.1.0 (https://satijalab.org/seurat/), transforming the data to loge(UMI+1) and applying a scale factor of 10,000.
T756 2652-2788 Sentence denotes For each array, we assessed the quality of constructed libraries by examining the distribution of reads, genes and transcripts per cell.
T757 2789-2918 Sentence denotes Variable gene selection, principal components analysis, and selection of significant principal components was performed as above.
T758 2919-3100 Sentence denotes We visualized our results in a two-dimensional space using UMAP (https://github.com/lmcinnes/umap), and annotated each cluster based on the identification of highly expressed genes.
T759 3101-3262 Sentence denotes To further characterize substructure within cell types (for example, T cells), we performed dimensionality reduction (PCA) and clustering over those cells alone.
T760 3263-3558 Sentence denotes Sub-clusters (i.e., clusters within broad cell type classifications) were annotated by cross-referencing cluster-defining genes with curated gene lists and online databases SaVanT (http://newpathways.mcdb.ucla.edu/savant-dev/) and GSEA/MsigDB (https://www.gsea-msigdb.org/gsea/msigdb/index.jsp).
T761 3559-3835 Sentence denotes Proliferating cells from the human lung (Figure 2C) express high levels of mitotic markers, such as MKI67, and represent primarily T cells (CD3D, CD3E), B cells/antibody-secreting cells (IGJ, MZB1, IGHG1), and myeloid cells (CD14, APOE) and represent a composite cell cluster.
T762 3836-4044 Sentence denotes Differential expression analysis between ACE2+ TMPRSS2+ and negative type II pneumocytes was performed in Seurat using a likelihood-ratio test (FindMarkers implemented in Seurat, setting “test.use” to bimod).
T763 4045-4252 Sentence denotes Expression data for epithelial cells included in this dataset can be visualized and downloaded here: https://singlecell.broadinstitute.org/single_cell/study/SCP814?scpbr=the-alexandria-project#study-summary.
T764 4254-4265 Sentence denotes Human Ileum
T765 4266-4439 Sentence denotes Libraries corresponding to 13 donors were sequenced using Illumina NovaSeq S2 with a Read 1 26bp, Read 2 91bp, Index 1 8bp configuration before reads were aligned to GRCh38.
T766 4440-4686 Sentence denotes Each sample was filtered individually for low quality cells and genes by analyzing distributions of reads, transcripts, percent reads mapped to mitochondrial genes, and complexity per cell, then merged as an outer join to create a single dataset.
T767 4687-4799 Sentence denotes Clustering and differential expression tests were processed using Seurat v3.1.0 (https://satijalab.org/seurat/).
T768 4800-4917 Sentence denotes Normalization and variable gene selection was processed with SCTransform (https://github.com/ChristophH/sctransform).
T769 4918-5108 Sentence denotes Clustering for major cell types was performed using Louvain clustering on dimensionally reduced PCA space with resolution set via grid search optimizing for maximum average silhouette score.
T770 5109-5234 Sentence denotes Due to the scale of the dataset, a randomized subsampling from across the dataset was used to calculate the silhouette score.
T771 5235-5548 Sentence denotes We annotated clusters based on highly expressed genes, then sub-clusters were characterized by performing PCA dimensionality reduction and clustering over those cells alone, and annotated based on highly expressed genes found via one-versus-rest differential expression test (Wilcoxon) within the major cell type.
T772 5549-5717 Sentence denotes Differential expression analysis between ACE2 + TMPRSS2 + and negative epithelial cells was performed in Seurat using a Wilcoxon test and Bonferroni p value correction.
T773 5718-5925 Sentence denotes Expression data for epithelial cells included in this dataset can be visualized and downloaded here: https://singlecell.broadinstitute.org/single_cell/study/SCP812?scpbr=the-alexandria-project#study-summary.
T774 5927-5951 Sentence denotes Human Adult Nasal Mucosa
T775 5952-6048 Sentence denotes Sample processing, sequencing, and analysis was performed as in (Ordovas-Montanes et al., 2018).
T776 6049-6242 Sentence denotes Briefly, scRNA-seq cell suspensions were freshly processed using Seq-Well v1 and Seurat v2.3.4 was utilized for computational analyses presented here (Butler et al., 2018, Satija et al., 2015).
T777 6243-6435 Sentence denotes Cell by gene matrix and R code for initialization of object available to download as Supplemental Data and Supplementary Tables here https://www.nature.com/articles/s41586-018-0449-8 and here:
T778 6436-6625 Sentence denotes http://shaleklab.com/resource/mapping-allergic-inflammation/? and visualized here: https://singlecell.broadinstitute.org/single_cell/study/SCP253?scpbr=the-alexandria-project#study-summary.
T779 6626-6889 Sentence denotes Scores for various cytokines acting on human airway epithelial cells were calculated based on gene lists derived for (Ordovas-Montanes et al., 2018), calculated using AddModuleScore function Seurat, and effect size calculated by Cohen’s d, as previously reported.
T780 6891-6957 Sentence denotes Granulomatous Tissue from Mycobacterium Tuberculosis Infected NHPs
T781 6958-7073 Sentence denotes Libraries corresponding to 10 animals (variable number of tissues/animal) were sequenced using Illumina NovaSeq S2.
T782 7074-7220 Sentence denotes Data was aligned using the Dropseq-tools pipeline on Terra (app.terra.bio) to M. fascicularis reference genome assembly 5, annotation version 101.
T783 7221-7336 Sentence denotes Clustering was performed using Leiden clustering in the Scanpy (scanpy.readthedocs.io) package (Wolf et al., 2018).
T784 7337-7393 Sentence denotes Cell type labels were assigned using known marker genes.
T785 7394-7540 Sentence denotes In this analysis, we include all epithelial cell subsets (secretory, multiciliated, type II pneumocytes, and type I pneumocytes) from all samples.
T786 7541-7804 Sentence denotes Differential expression between ACE2 + TMPRSS2 + cells and other cells of the matched cell subtype (e.g., Secretory Cells) were performed using the “bimod” likelihood-ratio test within each cell subtype and filtered on Benjamini-Hochberg-corrected p value < 0.05.
T787 7805-7905 Sentence denotes Expression data for epithelial cells included in this dataset can be visualized and downloaded here:
T788 7906-8012 Sentence denotes https://singlecell.broadinstitute.org/single_cell/study/SCP806?scpbr=the-alexandria-project#study-summary.
T789 8014-8045 Sentence denotes Basal Cell Cytokine Stimulation
T790 8046-8127 Sentence denotes Libraries corresponding to 279 populations were sequenced using Illumina NextSeq.
T791 8128-8308 Sentence denotes Reads were aligned to the hg19 or mm10 genome assembly using the cumulus platform https://cumulus-doc.readthedocs.io/en/0.12.0/smart_seq_2.html and output as TPM using RSEM v1.3.2.
T792 8309-8397 Sentence denotes Populations were transformed to transcripts per 10K reads and log2(1+TP10K) transformed.
T793 8398-8534 Sentence denotes ACE2 expression by stimulation condition and dose were assessed using one-way ANOVA with post hoc testing using a Bonferroni correction.
T794 8535-8799 Sentence denotes Plots were generated using ggplot2, and transcriptome-wide differential expression was calculated using the Seurat R package v3.1.0 (https://satijalab.org/seurat), function FindMarkers with test.use = ”bimod.” Expression data can be visualized and downloaded here:
T795 8800-8892 Sentence denotes https://singlecell.broadinstitute.org/single_cell/study/SCP822?scpbr=the-alexandria-project.
T796 8894-8936 Sentence denotes Interferon Treatment of Mouse Nasal Mucosa
T797 8937-9100 Sentence denotes Libraries corresponding to 4 mice, with 2 Seq-Well arrays per mouse were sequenced using Illumina NextSeq as described (Gierahn et al., 2017, Hughes et al., 2019).
T798 9101-9252 Sentence denotes Reads were aligned to the mm10 genome and processed according to the Drop-Seq Computational Protocol v2.0 (https://github.com/broadinstitute/Drop-seq).
T799 9253-9426 Sentence denotes Data was normalized and scaled using the Seurat R package v2.3.4 (https://satijalab.org/seurat/): transforming the data to loge(UMI+1) and applying a scale factor of 10,000.
T800 9427-9493 Sentence denotes Cells with fewer than 1000 UMIs and 500 unique genes were removed.
T801 9494-9654 Sentence denotes To identify major axes of variation within our data, we first examined only highly variable genes across all cells, yielding approximately 5,000 variable genes.
T802 9655-9767 Sentence denotes An approximate principal component analysis was applied to the cells to generate 200 principal components (PCs).
T803 9768-9953 Sentence denotes Using a combination of the Jackstraw function in Seurat and observing the “elbow” of the standard deviations of PCs, we chose the top 70 PCs for subsequent clustering and visualization.
T804 9954-10164 Sentence denotes For 2D visualization, we used a Uniform Manifold Approximation and Projection (UMAP) dimensionality reduction technique (https://github.com/lmcinnes/umap) with “min_dist” set to 0.3 and “n_neighbors” set to 50.
T805 10165-10379 Sentence denotes To identify clusters of transcriptionally similar cells, we employed unsupervised clustering as described above using the FindClusters tool within the Seurat R package with default parameters and k.param set to 10.
T806 10380-10473 Sentence denotes Resolution was chosen based on maximization of the average silhouette width across all cells.
T807 10474-10712 Sentence denotes Clusters were merged if a cell type expressed fewer than 25 significantly upregulated genes by differential expression test (FindAllMarkers implemented in Seurat, setting “test.use” to “bimod,” Bonferroni-adjusted p value cutoff < 0.001).
T808 10713-10873 Sentence denotes Differential expression tests between cells from saline-treated or IFNa-treated mice were assessed using the FindMarkers function with “test.use” set to “bimod.
T809 10874-10925 Sentence denotes This dataset can be visualized and downloaded here:
T810 10926-11032 Sentence denotes https://singlecell.broadinstitute.org/single_cell/study/SCP832?scpbr=the-alexandria-project#study-summary.
T811 11034-11079 Sentence denotes Lung from MHV68-Infected WT and IFNγR KO Mice
T812 11080-11212 Sentence denotes Libraries corresponding to 14 mice were aligned to a custom reference genome encompassing both murine (mm10) and herpes virus genes:
T813 11213-11317 Sentence denotes 84 known genes from MHV68 were retrieved from NCBI (NCBI: txid33708) and added to the mm10 mouse genome.
T814 11318-11477 Sentence denotes Reads were aligned to the custom joint genome and processed according to the Drop-Seq Computational Protocol v2.0 (https://github.com/broadinstitute/Drop-seq).
T815 11478-11622 Sentence denotes Barcodes with < 200 unique genes, > 20,000 UMI counts, and > 30% of transcript counts derived from mitochondrially encoded genes were discarded.
T816 11623-11880 Sentence denotes Data analysis was performed using the Scanpy Package following the common procedure, the expression matrices were normalized using scran’s size factor based approach and log transformed via scanpy’s pp.log1p() function (Lun et al., 2016, Wolf et al., 2018).
T817 11881-12066 Sentence denotes SoupX was utilized to reduce ambient RNA bias, using default parameters with pCut set to 0.3, and was applied to each sample before merging the count matrices (Young and Behjati, 2020).
T818 12067-12114 Sentence denotes UMI per cell and cell cycle were regressed out.
T819 12115-12353 Sentence denotes Highly variable genes were selected by running pp.highly_variable_genes() for each sample separately, returning the top 4,000 variable genes per sample, and genes identified in variable in > 5 samples were retained, yielding 14,305 genes.
T820 12354-12541 Sentence denotes Next, only Epcam+ cells were considered, principal components (PCs) were calculated using only the selected variable genes, and 6 PCs were used to perform unsupervised Louvain clustering.
T821 12542-12693 Sentence denotes Type I Pneumocytes were excluded from this analysis based on uniformly negative expression of Ace2, resulting in a final dataset subset of 5,558 cells.
T822 12694-12768 Sentence denotes Cells were identified as infected if at least one viral read was detected.
T823 12770-12809 Sentence denotes Nasal Washes during Influenza Infection
T824 12810-12893 Sentence denotes Sample processing, sequencing, and analysis was performed as in (Cao et al., 2020).
T825 12894-12976 Sentence denotes Reads were aligned to the GRCh37 reference genome combined with influenza genomes.
T826 12977-13162 Sentence denotes Mapped reads from each sample were then corrected for Drop-seq barcode synthesis error using the Drop-seq core computational tools developed by the McCarroll Lab (Macosko et al., 2015).
T827 13163-13324 Sentence denotes Genes were quantified using End Sequence Analysis Toolkit (ESAT, github/garber-lab/ESAT) with parameters -wlen 100 -wOlap 50 -wExt 0 -scPrep (Derr et al., 2016).
T828 13325-13522 Sentence denotes Finally, UMIs that likely result from sequencing errors were corrected by merging any UMIs that were observed only once and have 1 hamming distance from a UMI detected by two or more aligned reads.
T829 13523-13582 Sentence denotes Only cell barcodes with more than 1,000 UMIs were analyzed.
T830 13583-13651 Sentence denotes Cell barcodes with mostly erythrocyte genes (HBA, HBB) were removed.
T831 13652-13738 Sentence denotes From here on, the remaining cell barcodes in the matrix would be referred to as cells.
T832 13739-13833 Sentence denotes The final gene by cell matrix was normalized using the scran package v3.10 (Lun et al., 2016).
T833 13834-14029 Sentence denotes The normalized matrix was used for dimensionality reduction by first selecting variable genes that had a high coefficient of variance (CV) and were expressed (> = 1 UMI) by more than three cells.
T834 14030-14258 Sentence denotes Influenza viral genes, interferon stimulated genes, and cell cycle related genes were removed from the variable gene list in order to minimize the impact of viral responses and mitosis on clustering and cell type identification.
T835 14259-14469 Sentence denotes This resulted in the selection of 2484 variable genes. t-distributed stochastic neighbor embedding (tSNE) was applied to the first ten principal components (PCs), which explained 95% of the total data variance.
T836 14470-14658 Sentence denotes Density clustering (Rodriguez and Laio, 2014) was performed on the resulting tSNE coordinates and identified four major clusters: epithelial cells, neutrophils, macrophages and leukocytes.
T837 14659-14819 Sentence denotes The epithelial cell cluster and the leukocyte cluster were then re-clustered independently, as described above, to identify populations within each metacluster.
T838 14820-15014 Sentence denotes Specifically, the epithelial cell cluster was re-embedded using 2629 variable genes selected by the same criteria mentioned in the previous section and 13 PCs that explained 95% of the variance.
T839 15015-15088 Sentence denotes Density clustering over the epithelial cell subset revealed ten clusters.
T840 15089-15219 Sentence denotes Differential gene expression analysis using edgeR (Robinson et al., 2010) was performed to identify marker genes for each cluster.
T841 15220-15529 Sentence denotes Influenza-infected and bystander cells were identified after correcting for sample-specific distribution of ambient influenza mRNA contamination and predicted cells most likely to be infected identified using a hurdle zero inflated negative binomial (ZINB) model and a support vector machine (SVM) classifier.
T842 15531-15583 Sentence denotes Power Calculations for Detection of Rare Transcripts
T843 15584-15841 Sentence denotes We conducted the following statistical analysis to estimate the effects of various factors on our ability to make confident claims regarding the presence/absence of transcripts of interest (e.g., ACE2), both within individual cells and clusters (Figure S6).
T844 15842-15985 Sentence denotes Specifically, we investigated the roles of capture/reverse transcription efficiency, ACE2 expression level, sequencing depth, and cell numbers.
T845 15986-16242 Sentence denotes Taken together, the results of this power analysis are in agreement with other efforts to model biological and technical sources of zero-inflation within scRNA-seq data (e.g., https://satijalab.org/howmanycells and Kharchenko et al., 2014, Svensson, 2020).
T846 16243-16442 Sentence denotes We began by quantifying how likely we are to capture and transcribe at least one ACE2 mRNA molecule, as a function of the number ACE2 mRNA molecules per cell and a protocol’s efficiency (Figure S6A).
T847 16443-16809 Sentence denotes Drop-Seq has a capture/transcription efficiency of ∼10% (as estimated using ERCC spike ins; see (Macosko et al., 2015), and the experimental platforms used in this study are either equivalent (e.g., Seq-Well v1, (Gierahn et al., 2017) or superior (e.g., 10-fold better unique molecule detection, 5-fold better gene detection using Seq-Well S3;(Hughes et al., 2019)).
T848 16810-16937 Sentence denotes Most relevant to this context, inferior turbinate scrapings were processed using both Seq-Well v1 and Seq-Well S3 (Figure S3B).
T849 16938-17057 Sentence denotes Importantly, Seq-Well S3 provided > two-fold increase in the detection frequency of rare ACE2 transcripts (i.e., ACE2+:
T850 17058-17266 Sentence denotes 4.7% for v1 versus 9.8% for S3), making it reasonable to expect that such improvements in single-cell experimental technologies have yielded corresponding improvements in capture and transcription efficiency.
T851 17267-17776 Sentence denotes Based on Drop-Seq’s 10% efficiency, even if ACE2 is expressed at the low level of 5 mRNA molecules per cell (a reasonable order-of-magnitude estimate, given that non-human primate ileum cells had a maximum of 10 ACE2 unique molecules per cell observed via sequencing and an average of 1.93 molecules per cell in expressing cells, see Figures 3B and 3C), our experimental platforms have a minimum likelihood of 41% to capture and reverse transcribe at least one ACE2 mRNA molecule in any given individual cell.
T852 17777-18018 Sentence denotes This likelihood rapidly increases if we estimate higher efficiencies for improved scRNA-seq technologies (e.g., 67% likelihood within any individual cell at 20% capture/transcription efficiency, 76% likelihood at 25% efficiency, Figure S6A).
T853 18019-18326 Sentence denotes Thus, while transcript drop-out may reduce the fraction of positive cells, with the capture and transcription efficiencies of improved single-cell technologies, the impact is likely to be minor (reads are likely underestimated by up to a factor of ∼2.5x), given a sufficient depth of sequencing (see below).
T854 18327-18514 Sentence denotes We note that this impacts both clusters deemed to contain and not contain ACE2+ cells, and suggests our percentages are likely lower bounds for true expression (within a factor of ∼2.5x).
T855 18515-18694 Sentence denotes Next, we examined the probability of sequencing an ACE2 transcript as a function of read depth and ACE2’s fractional abundance in each single cell within our sequencing libraries.
T856 18695-19235 Sentence denotes First, across two different tissues (non-human primate ileum and lung, representing a high expresser of ACE2 and low expresser, respectively), we calculated the proportion of unique ACE2 molecules in our ACE2+ cells (defined as any cell with at least 1 UMI aligning to ACE2) as a fraction of total reads within individual cells to provide an order-of-magnitude estimate for average ACE2 abundance in our single-cell sequencing libraries (i.e., the probability that a read within a cell corresponds to a unique molecule of ACE2, Figure S6B).
T857 19236-19577 Sentence denotes We highlight that by calculating probabilities based on ACE2 unique molecules divided by an individual cell’s total reads, we are providing a conservative estimate for the probability of observing ACE2 as a function of sequencing depth (e.g., as compared to basing these probabilities on ACE2 non-UMI-collapsed reads divided by total reads).
T858 19578-19720 Sentence denotes Next, we obtained information on the number of reads in these cell populations to provide estimates of average sequencing depths (Figure S6C).
T859 19721-20005 Sentence denotes Using the mean fractional abundances of ACE2 from each tissue (Figure S6B) and the mean read depths for all genes (Figure S6C), we calculated the probability of detecting at least 1 ACE2 molecule (i.e., P(detecting > 0 ACE2 molecules) = 1 - (1 - ACE2 fractional abundance)Read depth).
T860 20006-20238 Sentence denotes This results in a 93.7% probability in ileum-derived cell libraries that contain ACE2, and a 76.0% probability for lung-derived cell libraries, indicating that our sequencing depths are sufficient to detect ACE2+ cells (Figure S6D).
T861 20239-20468 Sentence denotes To further evaluate whether our ability to detect ACE2+ cells was an artifact of sequencing depth, we compared the number of ACE2+ cells in a cluster to the mean number of reads across all cells in that same cluster (Figure S6E).
T862 20469-20802 Sentence denotes We did not observe any significant correlation: the ileum cell cluster with the highest number of ACE2+ cells had the lowest sequencing depth of all ileum clusters, and the lung cell cluster with the highest number of ACE2+ cells was approximately average in its read depth (on a log-log scale, Pearson’s r = −0.31, non-significant).
T863 20803-21334 Sentence denotes Further, when comparing ACE2+ cells to ACE2- cells within a given tissue, we did not observe a positive correlation between read depth and ACE2 status (i.e., mean ± standard error of the mean, SEM, reads among all lung cells = 28,512 ± 344; mean ± SEM reads among ACE2+ lung cells = 28,553 ± 2,988; mean ± SEM reads among all ileum cells = 14,864 ± 288; mean ± SEM reads among ACE2+ ileum cells = 10,591 ± 441, full statistics on cell depth among ACE2+ cells compared to ACE2- cells of the same cell type can be found in Table S9).
T864 21335-21478 Sentence denotes Thus, we can be confident that the observed differences in ACE2+ proportions across clusters are not driven by differences in sequencing depth.
T865 21479-21601 Sentence denotes Finally, we investigated how observed differences in ACE2+ proportions across clusters might be affected by cell sampling.
T866 21602-22024 Sentence denotes Using the proportion of ACE2+ cells in a “typical” cluster annotated as being ACE2 positive (i.e., 6.8% in non-human primate type II pneumocytes, Figure 1), we calculated the cluster sizes needed to be confident that the probability of observing zero to a few positive cells is unlikely to have arisen by random chance (probabilities calculated under a negative binomial distribution with parameter p = 0.068, Figure S6E).
T867 22025-22210 Sentence denotes We found that as cluster sizes approach and exceed 100 cells, the probability of observing zero to a few positive cells rapidly approaches zero, if we assume 6.8% of cells are positive.
T868 22211-22828 Sentence denotes Further, to examine our confidence in estimating an approximate upper bound (ignoring the impact of protocol inefficiencies discussed above) for the fraction of cells positive in a cluster as a function of the number of cells in that cluster, we also calculated the probability of observing zero (and its complement, probability of observing at least 1) ACE2+ cells as a function of cluster size across true positive proportions ranging from 0.1% to 10% (probabilities calculated under a negative binomial distribution with parameter p = 0.001 to 0.1, representing hypothetical proportions of ACE2+ cells Figure S6F).
T869 22829-23069 Sentence denotes Given our typical cluster sizes (on the order of hundreds of cells, exact values provided in Table S9), we find that for us to observe 0 ACE2+ cells in a cluster due to sampling artifacts, the fraction of true positives must be ∼1% or less.
T870 23070-23266 Sentence denotes Thus, these complementary approaches demonstrate that our observed variations in ACE2+ cell proportions across clusters likely reflect underlying biological differences, rather than random chance.
T871 23268-23287 Sentence denotes Statistical Testing
T872 23288-23509 Sentence denotes Parameters such as sample size, number of replicates, number of independent experiments, measures of center, dispersion, and precision (mean ± SEM) and statistical significances are reported in Figures and Figure Legends.
T873 23510-23562 Sentence denotes A p value less than 0.05 was considered significant.
T874 23563-23727 Sentence denotes Where appropriate, a Bonferroni or FDR correction was used to account for multiple tests, alternative correction methods are noted in the figure legends or Methods.
T875 23728-23873 Sentence denotes All statistical tests corresponding to differential gene expression are described above and completed using R language for Statistical Computing.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2691 45-50 Species denotes Human Tax:9606
2695 1867-1871 Gene denotes ACE2 Gene:59272
2696 1881-1885 Gene denotes ACE2 Gene:59272
2697 216-226 Species denotes M. mulatta Tax:9544
2699 2224-2229 Species denotes Human Tax:9606
2715 3659-3664 Gene denotes MKI67 Gene:4288
2716 3699-3703 Gene denotes CD3D Gene:915
2717 3705-3709 Gene denotes CD3E Gene:916
2718 3746-3749 Gene denotes IGJ Gene:3512
2719 3751-3755 Gene denotes MZB1 Gene:51237
2720 3757-3762 Gene denotes IGHG1 Gene:3500
2721 3790-3794 Gene denotes APOE Gene:348
2722 3877-3881 Gene denotes ACE2 Gene:59272
2723 3883-3890 Gene denotes TMPRSS2 Gene:7113
2724 3588-3593 Species denotes human Tax:9606
2725 3942-3948 Chemical denotes Seurat
2726 4007-4013 Chemical denotes Seurat
2727 4037-4042 Chemical denotes bimod
2728 3499-3505 Disease denotes MsigDB
2729 3519-3546 Disease denotes gsea-msigdb.org/gsea/msigdb
2731 4254-4259 Species denotes Human Tax:9606
2735 5590-5594 Gene denotes ACE2 Gene:59272
2736 5597-5604 Gene denotes TMPRSS2 Gene:7113
2737 4970-4977 Chemical denotes Louvain
2739 5927-5932 Species denotes Human Tax:9606
2743 6575-6578 Gene denotes SCP Gene:114131
2744 6665-6670 Species denotes human Tax:9606
2745 6474-6495 Disease denotes allergic-inflammation MESH:D007249
2747 6931-6957 Disease denotes Tuberculosis Infected NHPs MESH:D007239
2751 7573-7577 Gene denotes ACE2 Gene:59272
2752 7580-7587 Gene denotes TMPRSS2 Gene:7113
2753 7152-7167 Species denotes M. fascicularis Tax:9541
2755 7962-7965 Gene denotes SCP Gene:114131
2757 8398-8402 Gene denotes ACE2 Gene:59272
2759 8856-8859 Gene denotes SCP Gene:114131
2762 8894-8904 Gene denotes Interferon Gene:3439
2763 8918-8923 Species denotes Mouse Tax:10090
2768 10780-10784 Gene denotes IFNa Gene:111654
2769 8966-8970 Species denotes mice Tax:10090
2770 8999-9004 Species denotes mouse Tax:10090
2771 10793-10797 Species denotes mice Tax:10090
2773 10982-10985 Gene denotes SCP Gene:114131
2775 11044-11061 Disease denotes MHV68-Infected WT MESH:D007239
2783 12365-12370 Gene denotes Epcam Gene:4072
2784 12636-12640 Gene denotes Ace2 Gene:59272
2785 11110-11114 Species denotes mice Tax:10090
2786 11175-11181 Species denotes murine Tax:10090
2787 11233-11238 Species denotes MHV68 Tax:1440122
2788 11304-11309 Species denotes mouse Tax:10090
2789 12719-12727 Disease denotes infected MESH:D007239
2792 12790-12799 Species denotes Influenza Tax:11520
2793 12800-12809 Disease denotes Infection MESH:D007239
2802 14053-14063 Gene denotes interferon Gene:3439
2803 13633-13636 Gene denotes HBB Gene:3043
2804 12958-12967 Species denotes influenza Tax:11520
2805 14030-14039 Species denotes Influenza Tax:11520
2806 15220-15229 Species denotes Influenza Tax:11520
2807 15336-15345 Species denotes influenza Tax:11520
2808 15230-15238 Disease denotes infected MESH:D007239
2809 15403-15411 Disease denotes infected MESH:D007239
2812 15780-15784 Gene denotes ACE2 Gene:59272
2813 15927-15931 Gene denotes ACE2 Gene:59272
2824 16324-16328 Gene denotes ACE2 Gene:59272
2825 16372-16376 Gene denotes ACE2 Gene:59272
2826 17027-17031 Gene denotes ACE2 Gene:59272
2827 17051-17055 Gene denotes ACE2 Gene:59272
2828 17311-17315 Gene denotes ACE2 Gene:59272
2829 17479-17483 Gene denotes ACE2 Gene:59272
2830 17728-17732 Gene denotes ACE2 Gene:59272
2831 18401-18405 Gene denotes ACE2 Gene:59272
2832 16524-16529 Gene denotes spike Gene:43740568
2833 17433-17438 Species denotes human Tax:9606
2852 18566-18570 Gene denotes ACE2 Gene:59272
2853 18614-18618 Gene denotes ACE2 Gene:59272
2854 18799-18803 Gene denotes ACE2 Gene:59272
2855 18877-18881 Gene denotes ACE2 Gene:59272
2856 18899-18903 Gene denotes ACE2 Gene:59272
2857 18964-18968 Gene denotes ACE2 Gene:59272
2858 19077-19081 Gene denotes ACE2 Gene:59272
2859 19217-19221 Gene denotes ACE2 Gene:59272
2860 19292-19296 Gene denotes ACE2 Gene:59272
2861 19433-19437 Gene denotes ACE2 Gene:59272
2862 19524-19528 Gene denotes ACE2 Gene:59272
2863 19761-19765 Gene denotes ACE2 Gene:59272
2864 19903-19907 Gene denotes ACE2 Gene:59272
2865 19940-19944 Gene denotes ACE2 Gene:59272
2866 19967-19971 Gene denotes ACE2 Gene:59272
2867 20087-20091 Gene denotes ACE2 Gene:59272
2868 20213-20217 Gene denotes ACE2 Gene:59272
2869 18736-18741 Species denotes human Tax:9606
2882 20289-20293 Gene denotes ACE2 Gene:59272
2883 20364-20368 Gene denotes ACE2 Gene:59272
2884 20567-20571 Gene denotes ACE2 Gene:59272
2885 20687-20691 Gene denotes ACE2 Gene:59272
2886 20827-20831 Gene denotes ACE2 Gene:59272
2887 20842-20846 Gene denotes ACE2 Gene:59272
2888 20942-20946 Gene denotes ACE2 Gene:59272
2889 21067-21071 Gene denotes ACE2 Gene:59272
2890 21180-21184 Gene denotes ACE2 Gene:59272
2891 21250-21254 Gene denotes ACE2 Gene:59272
2892 21274-21278 Gene denotes ACE2 Gene:59272
2893 21394-21398 Gene denotes ACE2 Gene:59272
2902 21532-21536 Gene denotes ACE2 Gene:59272
2903 21626-21630 Gene denotes ACE2 Gene:59272
2904 21680-21684 Gene denotes ACE2 Gene:59272
2905 22565-22569 Gene denotes ACE2 Gene:59272
2906 22804-22808 Gene denotes ACE2 Gene:59272
2907 22966-22970 Gene denotes ACE2 Gene:59272
2908 23151-23155 Gene denotes ACE2 Gene:59272
2909 21713-21718 Species denotes human Tax:9606

2_test

Id Subject Object Predicate Lexical cue
32413319-24836921-20790576 1992-1996 24836921 denotes 2014
32413319-30135581-20790577 6042-6046 30135581 denotes 2018
32413319-29608179-20790578 6215-6219 29608179 denotes 2018
32413319-25867923-20790579 6236-6240 25867923 denotes 2015
32413319-30135581-20790580 6769-6773 30135581 denotes 2018
32413319-29409532-20790581 7330-7334 29409532 denotes 2018
32413319-28192419-20790582 9073-9077 28192419 denotes 2017
32413319-27909575-20790583 11855-11859 27909575 denotes 2016
32413319-29409532-20790584 11874-11878 29409532 denotes 2018
32413319-26000488-20790585 13156-13160 26000488 denotes 2015
32413319-27470110-20790586 13318-13322 27470110 denotes 2016
32413319-27909575-20790587 13827-13831 27909575 denotes 2016
32413319-24970081-20790588 14510-14514 24970081 denotes 2014
32413319-19910308-20790589 15157-15161 19910308 denotes 2010
32413319-24836921-20790590 16220-16224 24836921 denotes 2014
32413319-31937974-20790591 16236-16240 31937974 denotes 2020
32413319-26000488-20790592 16556-16560 26000488 denotes 2015
32413319-28192419-20790593 16672-16676 28192419 denotes 2017