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PMC:7247521 / 43581-44500 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
771 223-227 Gene denotes ACE2 Gene:59272
772 302-306 Gene denotes ACE2 Gene:59272
773 507-511 Gene denotes ACE2 Gene:59272
774 48-57 Species denotes 2019-nCov Tax:2697049
775 482-491 Species denotes 2019-nCov Tax:2697049
776 84-95 Disease denotes dysfunction MESH:D009461
777 493-502 Disease denotes pneumonia MESH:D011014
778 591-599 Disease denotes COVID-19 MESH:C000657245
779 732-740 Disease denotes COVID-19 MESH:C000657245
780 774-795 Disease denotes inflammatory diseases MESH:D007249
781 797-803 Disease denotes asthma MESH:D001249
782 805-831 Disease denotes inflammatory bowel disease MESH:D015212
783 833-870 Disease denotes chronic obstructive pulmonary disease MESH:D029424
784 872-896 Disease denotes intrahepatic cholestasis MESH:D002780
785 906-913 Disease denotes ileitis MESH:D007079

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T650 48-57 SP_7 denotes 2019-nCov
T651 77-83 UBERON:0000062 denotes organs
T652 107-112 UBERON:0002107 denotes liver
T653 119-127 UBERON:0001264 denotes pancreas
T654 134-140 UBERON:0002113 denotes kidney
T655 147-153 UBERON:0000341 denotes throat
T656 158-164 UBERON:0001052 denotes rectum
T657 223-227 G_3;PG_10;PR:000003622 denotes ACE2
T658 241-248 UBERON:0000479 denotes tissues
T659 302-306 G_3;PG_10;PR:000003622 denotes ACE2
T660 318-327 GO:0010467 denotes expressed
T661 340-345 UBERON:0002116 denotes ileum
T662 347-353 UBERON:0000473 denotes testis
T663 355-362 UBERON:0001013 denotes adipose
T664 363-371 UBERON:0004877 denotes visceral
T665 372-379 UBERON:0003688 denotes omentum
T666 381-401 UBERON:0002084 denotes heart left ventricle
T667 403-416 UBERON:0001225 denotes kidney cortex
T668 421-428 UBERON:0002046 denotes thyroid
T669 482-491 SP_7 denotes 2019-nCov
T670 507-511 G_3;PG_10;PR:000003622 denotes ACE2
T671 520-525 SO:0000704 denotes genes
T672 591-599 SP_7 denotes COVID-19
T673 732-740 SP_7 denotes COVID-19
T674 805-823 UBERON:0000160 denotes inflammatory bowel
T675 853-862 UBERON:0002048 denotes pulmonary
T676 872-884 UBERON:0000160 denotes intrahepatic

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T172 107-112 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T173 119-127 Body_part denotes pancreas http://purl.org/sig/ont/fma/fma7198
T174 134-140 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T175 147-153 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T176 158-164 Body_part denotes rectum http://purl.org/sig/ont/fma/fma14544
T177 241-248 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T178 331-345 Body_part denotes terminal ileum http://purl.org/sig/ont/fma/fma14966
T179 347-353 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210
T180 372-379 Body_part denotes omentum http://purl.org/sig/ont/fma/fma14650
T181 381-386 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T182 387-401 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T183 403-409 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T184 410-416 Body_part denotes cortex http://purl.org/sig/ont/fma/fma61109
T185 421-428 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T186 818-823 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T51 77-83 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T52 107-112 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T53 119-127 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264
T54 134-140 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T55 147-153 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T56 158-164 Body_part denotes rectum http://purl.obolibrary.org/obo/UBERON_0001052
T57 340-345 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T58 347-353 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473
T59 372-379 Body_part denotes omentum http://purl.obolibrary.org/obo/UBERON_0003688
T60 381-401 Body_part denotes heart left ventricle http://purl.obolibrary.org/obo/UBERON_0002084
T61 381-386 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T62 403-409 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T63 410-416 Body_part denotes cortex http://purl.obolibrary.org/obo/UBERON_0001851
T64 421-428 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T91 119-127 Disease denotes pancreas http://purl.obolibrary.org/obo/MONDO_0021040
T92 493-502 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T93 591-599 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 732-740 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 774-795 Disease denotes inflammatory diseases http://purl.obolibrary.org/obo/MONDO_0021166
T96 797-803 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T97 805-831 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T98 833-870 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T99 853-870 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T100 872-896 Disease denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/MONDO_0019072
T101 885-896 Disease denotes cholestasis http://purl.obolibrary.org/obo/MONDO_0001751
T102 906-913 Disease denotes ileitis http://purl.obolibrary.org/obo/MONDO_0000709

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T372 11-12 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T373 77-83 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T374 107-112 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T375 107-112 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T376 114-116 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T377 119-127 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
T378 129-131 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T379 134-140 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T380 134-140 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T381 134-140 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T382 142-144 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T383 158-164 http://purl.obolibrary.org/obo/UBERON_0001052 denotes rectum
T384 158-164 http://purl.obolibrary.org/obo/UBERON_0006866 denotes rectum
T385 200-201 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T386 340-345 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T387 347-353 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis
T388 355-362 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose
T389 372-379 http://purl.obolibrary.org/obo/UBERON_0003688 denotes omentum
T390 381-386 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T391 381-386 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T392 381-386 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T393 381-386 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T394 403-409 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T395 403-409 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T396 403-409 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T397 410-416 http://purl.obolibrary.org/obo/UBERON_0001851 denotes cortex
T398 445-448 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T399 520-525 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T400 615-616 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T350 647-650 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T26 493-502 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T27 797-803 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T28 805-831 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T29 833-870 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T30 872-896 Phenotype denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/HP_0001406
T31 906-913 Phenotype denotes ileitis http://purl.obolibrary.org/obo/HP_0032564

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T327 0-254 Sentence denotes Currently, a number of studies have showed that 2019-nCov can cause multiple organs dysfunction, including liver [34], pancreas [35], kidney [36], throat and rectum [37], which may be the reason that a wide distribution of ACE2 across these tissues [38].
T328 255-526 Sentence denotes In agreement with these results, we found that ACE2 was highly expressed in terminal ileum, testis, adipose visceral omentum, heart left ventricle, kidney cortex and thyroid, etc., and QFPD has only 15.33 % common targets with 2019-nCov, pneumonia and ACE2 related genes.
T329 527-636 Sentence denotes These results indicate that the effective treatment of QFPD for COVID-19 may be through a holistic treatment.
T330 637-919 Sentence denotes Moreover, TTD analysis further displayed that QFPD targets were significantly enriched in many COVID-19 related disease, such as chronic inflammatory diseases, asthma, inflammatory bowel disease, chronic obstructive pulmonary disease, intrahepatic cholestasis, chronic ileitis, etc.