PMC:7247521 / 29019-29544 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"446","span":{"begin":208,"end":223},"obj":"Gene"},{"id":"447","span":{"begin":286,"end":290},"obj":"Gene"},{"id":"448","span":{"begin":306,"end":310},"obj":"Gene"},{"id":"449","span":{"begin":329,"end":333},"obj":"Gene"},{"id":"450","span":{"begin":355,"end":363},"obj":"Gene"},{"id":"451","span":{"begin":382,"end":390},"obj":"Gene"},{"id":"452","span":{"begin":292,"end":297},"obj":"Gene"},{"id":"453","span":{"begin":19,"end":27},"obj":"Disease"}],"attributes":[{"id":"A447","pred":"tao:has_database_id","subj":"447","obj":"Gene:8673700"},{"id":"A448","pred":"tao:has_database_id","subj":"448","obj":"Gene:43740578"},{"id":"A449","pred":"tao:has_database_id","subj":"449","obj":"Gene:43740578"},{"id":"A450","pred":"tao:has_database_id","subj":"450","obj":"Gene:164045"},{"id":"A451","pred":"tao:has_database_id","subj":"451","obj":"Gene:164045"},{"id":"A452","pred":"tao:has_database_id","subj":"452","obj":"Gene:43740578"},{"id":"A453","pred":"tao:has_database_id","subj":"453","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T373","span":{"begin":19,"end":27},"obj":"SP_7"},{"id":"T374","span":{"begin":130,"end":139},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T375","span":{"begin":299,"end":304},"obj":"PR:000000125"},{"id":"T376","span":{"begin":322,"end":327},"obj":"PR:000000125"},{"id":"T377","span":{"begin":348,"end":353},"obj":"PR:000000125"},{"id":"T378","span":{"begin":364,"end":372},"obj":"SO:0000346"},{"id":"T379","span":{"begin":375,"end":380},"obj":"PR:000000125"},{"id":"T380","span":{"begin":402,"end":407},"obj":"PR:000000125"},{"id":"T381","span":{"begin":416,"end":421},"obj":"PR:000000125"},{"id":"T382","span":{"begin":434,"end":439},"obj":"PR:000000125"},{"id":"T383","span":{"begin":460,"end":465},"obj":"PR:000000125"},{"id":"T384","span":{"begin":480,"end":489},"obj":"PG_4"},{"id":"T385","span":{"begin":500,"end":509},"obj":"PG_2"},{"id":"T386","span":{"begin":511,"end":514},"obj":"CHEBI:24870;CHEBI:24870"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T95","span":{"begin":276,"end":284},"obj":"Body_part"},{"id":"T96","span":{"begin":316,"end":319},"obj":"Body_part"},{"id":"T97","span":{"begin":342,"end":345},"obj":"Body_part"},{"id":"T98","span":{"begin":409,"end":413},"obj":"Body_part"},{"id":"T99","span":{"begin":482,"end":489},"obj":"Body_part"},{"id":"T100","span":{"begin":502,"end":509},"obj":"Body_part"}],"attributes":[{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma84120"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T60","span":{"begin":19,"end":27},"obj":"Disease"}],"attributes":[{"id":"A60","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T247","span":{"begin":141,"end":143},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T248","span":{"begin":204,"end":206},"obj":"http://purl.obolibrary.org/obo/CLO_0008933"},{"id":"T249","span":{"begin":229,"end":232},"obj":"http://purl.obolibrary.org/obo/CLO_0007875"},{"id":"T250","span":{"begin":229,"end":232},"obj":"http://purl.obolibrary.org/obo/CLO_0052410"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T192","span":{"begin":4,"end":15},"obj":"Chemical"},{"id":"T193","span":{"begin":200,"end":202},"obj":"Chemical"},{"id":"T195","span":{"begin":204,"end":206},"obj":"Chemical"},{"id":"T196","span":{"begin":225,"end":227},"obj":"Chemical"},{"id":"T197","span":{"begin":276,"end":284},"obj":"Chemical"},{"id":"T198","span":{"begin":364,"end":367},"obj":"Chemical"},{"id":"T201","span":{"begin":482,"end":489},"obj":"Chemical"},{"id":"T202","span":{"begin":502,"end":509},"obj":"Chemical"},{"id":"T203","span":{"begin":511,"end":514},"obj":"Chemical"}],"attributes":[{"id":"A192","pred":"chebi_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A193","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_51083"},{"id":"A194","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_53453"},{"id":"A195","pred":"chebi_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/CHEBI_29386"},{"id":"A196","pred":"chebi_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/CHEBI_15379"},{"id":"A197","pred":"chebi_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A198","pred":"chebi_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/CHEBI_16761"},{"id":"A199","pred":"chebi_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/CHEBI_456216"},{"id":"A200","pred":"chebi_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/CHEBI_73342"},{"id":"A201","pred":"chebi_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A202","pred":"chebi_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A203","pred":"chebi_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/CHEBI_24870"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T100","span":{"begin":511,"end":522},"obj":"http://purl.obolibrary.org/obo/GO_0022831"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-sentences","denotations":[{"id":"T216","span":{"begin":0,"end":525},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T3","span":{"begin":186,"end":189},"obj":"GlycoEpitope"}],"attributes":[{"id":"A3","pred":"glyco_epitope_db_id","subj":"T3","obj":"http://www.glycoepitope.jp/epitopes/AN0690"}],"text":"The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel])."}