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PMC:7247521 / 28996-35288 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
418 1094-1098 Gene denotes RdRp Gene:43740578
419 1163-1167 Gene denotes RdRp Gene:43740578
420 1235-1243 Gene denotes Helicase Gene:164045
421 1304-1312 Gene denotes Helicase Gene:164045
423 890-899 Species denotes 2019-nCov Tax:2697049
425 1832-1835 Disease denotes XCH
429 2164-2170 Gene denotes ClC −6 Gene:1185
430 1954-1966 Disease denotes SGMH XCH WLS
431 2075-2078 Disease denotes APL MESH:D015473
433 1922-1930 Disease denotes COVID-19 MESH:C000657245
436 2598-2602 Chemical denotes BXTM
437 2460-2463 Disease denotes APL MESH:D015473
446 231-246 Gene denotes SX1, O1, X2, X1
447 309-313 Gene denotes Mpro Gene:8673700
448 329-333 Gene denotes RdRp Gene:43740578
449 352-356 Gene denotes RdRp Gene:43740578
450 378-386 Gene denotes Helicase Gene:164045
451 405-413 Gene denotes Helicase Gene:164045
452 315-320 Gene denotes PLpro Gene:43740578
453 42-50 Disease denotes COVID-19 MESH:C000657245
480 2914-2922 Gene denotes Helicase Gene:164045
481 3583-3587 Gene denotes Mpro Gene:8673700
482 3811-3815 Gene denotes Mpro Gene:8673700
483 3366-3371 Gene denotes PLpro Gene:43740578
484 3142-3150 Gene denotes Helicase Gene:164045
485 2809-2812 Chemical denotes TYR MESH:D014443
486 2817-2820 Chemical denotes ALA MESH:D000409
487 2825-2828 Chemical denotes ILE MESH:D007532
488 2836-2839 Chemical denotes PRO MESH:D011392
489 3014-3017 Chemical denotes ASN MESH:D001216
490 3023-3026 Chemical denotes ARG MESH:D001120
491 3032-3035 Chemical denotes LEU MESH:D007930
492 3043-3046 Chemical denotes PRO MESH:D011392
493 3628-3636 Chemical denotes hydrogen MESH:D006859
494 3691-3694 Chemical denotes GLU MESH:D018698
495 3700-3703 Chemical denotes LEU MESH:D007930
496 3712-3715 Chemical denotes CYS MESH:D003545
497 3726-3728 Chemical denotes O2 MESH:D010100
498 3847-3853 Chemical denotes Carbon MESH:D002244
499 3854-3862 Chemical denotes hydrogen MESH:D006859
500 3872-3877 Chemical denotes anion MESH:D000838
501 3882-3888 Chemical denotes sulfur MESH:D013455
502 3938-3941 Chemical denotes GLY
503 3946-3949 Chemical denotes LEU MESH:D007930
504 3958-3961 Chemical denotes CYS MESH:D003545
505 3547-3550 Disease denotes XCH
512 6145-6149 Gene denotes RdRp Gene:43740578
513 6182-6186 Gene denotes RdRp Gene:43740578
514 5917-5925 Disease denotes COVID-19 MESH:C000657245
515 6230-6233 Disease denotes XCH
516 6248-6251 Disease denotes XCH
517 6277-6280 Disease denotes XCH
537 5357-5361 Gene denotes RdRp Gene:43740578
538 5637-5641 Gene denotes RdRp Gene:43740578
539 4612-4615 Chemical denotes PRO MESH:D011392
540 4621-4624 Chemical denotes VAL MESH:D014633
541 4630-4633 Chemical denotes LYS MESH:D008239
542 4642-4645 Chemical denotes SER MESH:D012694
543 4818-4821 Chemical denotes PHE MESH:D010649
544 4987-4990 Chemical denotes LYS MESH:D008239
545 4996-4999 Chemical denotes LYS MESH:D008239
546 5005-5008 Chemical denotes VAL MESH:D014633
547 5017-5020 Chemical denotes PRO MESH:D011392
548 5692-5700 Chemical denotes hydrogen MESH:D006859
549 5762-5765 Chemical denotes CYS MESH:D003545
550 5771-5774 Chemical denotes GLY
551 5780-5783 Chemical denotes LYS MESH:D008239
552 5792-5795 Chemical denotes ASP MESH:D001224
553 4474-4477 Disease denotes XCH
554 4703-4706 Disease denotes XCH
555 5585-5588 Disease denotes XCH

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T373 42-50 SP_7 denotes COVID-19
T374 153-162 CHEBI:36357;CHEBI:36357 denotes compounds
T375 322-327 PR:000000125 denotes nsp12
T376 345-350 PR:000000125 denotes nsp12
T377 371-376 PR:000000125 denotes nsp13
T378 387-395 SO:0000346 denotes ADP site
T379 398-403 PR:000000125 denotes nsp13
T380 425-430 PR:000000125 denotes nsp14
T381 439-444 PR:000000125 denotes nsp14
T382 457-462 PR:000000125 denotes nsp15
T383 483-488 PR:000000125 denotes nsp16
T384 503-512 PG_4 denotes N protein
T385 523-532 PG_2 denotes E protein
T386 534-537 CHEBI:24870;CHEBI:24870 denotes ion
T387 709-718 CHEBI:36357;CHEBI:36357 denotes compounds
T388 761-770 CHEBI:36357;CHEBI:36357 denotes compounds
T389 816-825 CHEBI:36357;CHEBI:36357 denotes compounds
T397 890-899 SP_7 denotes 2019-nCov
T398 1922-1930 SP_7 denotes COVID-19
T399 2390-2394 CHEBI:23888;CHEBI:23888 denotes drug
T400 2566-2570 CHEBI:23888;CHEBI:23888 denotes drug
T401 2661-2669 CHEBI:36357;CHEBI:36357 denotes compound
T402 2719-2728 PG_2 denotes E protein
T403 2730-2733 CHEBI:24870;CHEBI:24870 denotes ion
T404 3077-3085 CHEBI:36357;CHEBI:36357 denotes compound
T405 3135-3140 PR:000000125 denotes nsp13
T406 3207-3212 CHEBI:32988;CHEBI:32988 denotes Amide
T407 3385-3390 CHEBI:22563;CHEBI:22563 denotes anion
T408 3526-3534 CHEBI:36357;CHEBI:36357 denotes compound
T409 3726-3728 CHEBI:15379;CHEBI:15379 denotes O2
T410 3751-3759 CHEBI:36357;CHEBI:36357 denotes compound
T411 3872-3877 CHEBI:22563;CHEBI:22563 denotes anion
T412 3990-3998 CHEBI:36357;CHEBI:36357 denotes compound
T413 4058-4067 PG_4 denotes N protein
T414 4296-4301 PR:000000125 denotes nsp14
T415 4444-4452 CHEBI:36357;CHEBI:36357 denotes compound
T416 4510-4515 PR:000000125 denotes nsp15
T417 4656-4659 PR:P19339 denotes SX1
T418 4673-4681 CHEBI:36357;CHEBI:36357 denotes compound
T419 4737-4742 PR:000000125 denotes nsp14
T420 4841-4844 PR:P19339 denotes SX1
T421 4885-4890 PR:000000125 denotes nsp15
T422 5043-5051 CHEBI:36357;CHEBI:36357 denotes compound
T423 5111-5116 PR:000000125 denotes nsp16
T424 5202-5207 CHEBI:17478;CHEBI:17478 denotes alkyl
T425 5215-5220 CHEBI:22563;CHEBI:22563 denotes anion
T426 5350-5355 PR:000000125 denotes nsp12
T427 5456-5462 CHEBI:36916;CHEBI:36916 denotes cation
T428 5470-5475 CHEBI:22563;CHEBI:22563 denotes anion
T429 5564-5572 CHEBI:36357;CHEBI:36357 denotes compound
T430 5630-5635 PR:000000125 denotes nsp12
T431 5881-5890 CHEBI:36357;CHEBI:36357 denotes compounds
T432 5917-5925 SP_7 denotes COVID-19
T433 5947-5956 PG_4 denotes N protein
T434 5970-5973 PR:Q8K4K7 denotes MS1
T435 5978-5983 PR:000000125 denotes nsp14
T436 6004-6009 PR:000000125 denotes nsp15
T437 6033-6036 PR:P19339 denotes SX1
T438 6041-6046 PR:000000125 denotes nsp14
T439 6062-6065 PR:P19339 denotes SX1
T440 6070-6075 PR:000000125 denotes nsp15
T441 6107-6112 PR:000000125 denotes nsp16
T442 6138-6143 PR:000000125 denotes nsp12
T443 6175-6180 PR:000000125 denotes nsp12

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T95 299-307 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T96 339-342 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T97 365-368 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T98 432-436 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T99 505-512 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T100 525-532 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T101 900-908 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T102 1104-1107 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T103 1176-1179 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T104 1383-1387 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T105 1667-1674 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T106 1737-1744 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T107 2721-2728 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T108 4060-4067 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T109 4303-4307 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T110 5370-5373 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T111 5647-5650 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T112 5926-5934 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T113 5949-5956 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T114 5985-5989 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T115 6158-6161 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T116 6192-6195 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T60 42-50 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T61 1922-1930 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 5917-5925 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T247 164-166 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T248 227-229 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T249 252-255 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T250 252-255 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T251 925-927 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T252 928-930 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T253 2164-2167 http://purl.obolibrary.org/obo/CLO_0002494 denotes ClC
T254 2288-2291 http://purl.obolibrary.org/obo/CLO_0002494 denotes ClC
T255 2650-2651 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T256 3052-3054 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T257 3066-3067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T258 3323-3325 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T259 3515-3516 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T260 3740-3741 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T261 3942-3944 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T262 3972-3975 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T263 3972-3975 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T264 3984-3985 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T265 3988-3989 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T266 4252-4255 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T267 4252-4255 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T268 4413-4416 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T269 4442-4443 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T270 4621-4624 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T271 4646-4649 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T272 4646-4649 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T273 4646-4649 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T274 4646-4649 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T275 4646-4649 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T276 4646-4649 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T277 4646-4649 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T278 4671-4672 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T279 5005-5008 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T280 5041-5042 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T281 5507-5510 http://purl.obolibrary.org/obo/CLO_0001417 denotes 556
T282 5562-5563 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T283 5608-5611 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T284 5766-5769 http://purl.obolibrary.org/obo/CLO_0001001 denotes 813
T285 5936-5937 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T286 5939-5942 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T287 5939-5942 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T288 5967-5968 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T289 5970-5973 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T290 5970-5973 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T291 6198-6200 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T192 27-38 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T193 223-225 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T195 227-229 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T196 248-250 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T197 299-307 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T198 387-390 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T201 505-512 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T202 525-532 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T203 534-537 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T204 900-908 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T205 919-921 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T207 928-930 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T208 950-952 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T209 1244-1247 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T212 1667-1674 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T213 1737-1744 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T214 1745-1748 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T215 2390-2394 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T216 2566-2570 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T217 2636-2638 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T219 2721-2728 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T220 2730-2733 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T221 2753-2755 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T222 2763-2765 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T223 2817-2820 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T225 2864-2866 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T227 2955-2960 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T229 2961-2966 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T231 2968-2970 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T232 3014-3017 Chemical denotes ASN http://purl.obolibrary.org/obo/CHEBI_22653
T233 3151-3154 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T236 3207-3212 Chemical denotes Amide http://purl.obolibrary.org/obo/CHEBI_32988
T237 3213-3215 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T238 3228-3230 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T239 3264-3267 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T241 3382-3384 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T242 3385-3390 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T243 3392-3394 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T244 3395-3397 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T245 3407-3409 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T246 3410-3412 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T247 3426-3428 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T248 3619-3621 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T249 3622-3627 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T251 3628-3636 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T252 3646-3648 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T253 3726-3728 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T254 3847-3853 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T255 3854-3862 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T256 3869-3871 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T257 3872-3877 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T258 3879-3881 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T259 3882-3888 Chemical denotes sulfur http://purl.obolibrary.org/obo/CHEBI_26833
T260 3893-3895 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T261 4060-4067 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T262 4108-4110 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T263 4111-4116 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T265 4117-4125 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T266 4132-4134 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T267 4142-4144 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T268 4145-4147 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T269 4160-4162 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T270 4213-4216 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T272 4343-4345 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T273 4346-4348 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T274 4392-4395 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T275 4576-4578 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T276 4630-4633 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T277 4764-4766 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T278 4767-4769 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T279 4782-4784 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T280 4818-4821 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T281 4951-4953 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T282 4987-4990 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T283 4996-4999 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T284 5036-5038 Chemical denotes 9F http://purl.obolibrary.org/obo/CHEBI_24061
T285 5161-5167 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T286 5168-5176 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T287 5183-5185 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T288 5186-5188 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T289 5199-5201 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T290 5212-5214 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T291 5215-5220 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T292 5248-5251 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T293 5406-5412 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T294 5413-5421 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T295 5440-5445 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T297 5446-5451 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T299 5453-5455 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T300 5456-5462 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T301 5467-5469 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T302 5470-5475 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T303 5683-5685 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T304 5686-5691 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T306 5692-5700 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T307 5707-5709 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T308 5710-5712 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T309 5726-5728 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T310 5780-5783 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T311 5926-5934 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T312 5949-5956 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T313 6198-6200 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T100 534-545 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T101 1745-1756 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T102 2730-2741 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T215 0-22 Sentence denotes 3.6 Molecular docking
T216 23-548 Sentence denotes The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel]).
T217 549-603 Sentence denotes The docking scores were depicted in Table 3, Table 4 .
T218 604-748 Sentence denotes The smaller of docking score, the lower of energy would be required, which means the binding between the compounds and the targets are stronger.
T219 749-826 Sentence denotes There are 9 compounds presenting better bonding ability than other compounds.
T220 827-909 Sentence denotes Table 3 Docking score between specific ingredients of QFPD and 2019-nCov proteins.
T221 910-952 Sentence denotes Molecule M3 M5 S1 S5 W11 W5 X1 X2 X4 O1 O2
T222 953-1021 Sentence denotes Main Protease −7.7 −7.3 −6.8 −6.9 −7.2 −7.5 −7.1 −7.9 −7.3 −7.1 −7.4
T223 1022-1093 Sentence denotes Papain-like protease −8.7 −8.5 −9.9 −7.7 −8 −8 −8.4 −8.7 −8.2 −8.6 −8.2
T224 1094-1162 Sentence denotes RdRp with RNA −8.4 −8.5 −8.5 −8.3 −9.1 −9.1 −8.4 −8.2 −8.2 −8.3 −8.6
T225 1163-1234 Sentence denotes RdRp without RNA −6.8 −6.8 −6.9 −6.8 −6.7 −6.9 −7.1 −7.2 −6.5 −7.3 −7.1
T226 1235-1303 Sentence denotes Helicase ADP site −6.3 −6.3 −7.3 −6.5 −6 −6 −6.3 −6.5 −6.2 −6.1 −6.5
T227 1304-1376 Sentence denotes Helicase NCB site −7.9 −6.9 −7.2 −7.1 −7.2 −7.2 −7.4 −7.5 −7.3 −7.4 −7.4
T228 1377-1443 Sentence denotes Nsp14(ExoN) −6.8 −6.6 −6.3 −6.4 −6.9 −6.8 −6.7 −6.9 −6.4 −6.6 −6.9
T229 1444-1512 Sentence denotes Nsp14(N7-MTase) −8.8 −8.1 −8.5 −7.5 −8.4 −8.4 −8.3 −8.5 −8 −8.3 −8.5
T230 1513-1591 Sentence denotes Nsp15(endoribonuclease) −6.6 −6.3 −6.3 −5.9 −6.2 −6.2 −6.2 −6.3 −6.2 −6.4 −6.4
T231 1592-1664 Sentence denotes Nsp16(2′-O-MTase) −7.5 −7.4 −7.5 −7.2 −8.2 −8.2 −7.7 −7.9 −7.7 −7.9 −8.4
T232 1665-1734 Sentence denotes N protein NCB site −7.6 −7.5 −7.8 −7.6 −7.6 −7.6 −8 −8 −7.5 −7.6 −7.6
T233 1735-1810 Sentence denotes E protein(ion channel) −8.1 −7 −7.8 −6.7 −6.4 −6.4 −7.2 −7.3 −7.2 −7.1 −6.8
T234 1811-1839 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T235 1840-1847 Sentence denotes Others.
T236 1848-1939 Sentence denotes Table 4 Evaluation of the effect of QFPD on the robustness disturbance of COVID-19 network.
T237 1940-1983 Sentence denotes Topology MXSG SGMH XCH WLS Others BXTM YDBF
T238 1984-2029 Sentence denotes DTS 25.66 26.71 21.02 17.64 23.16 14.52 22.71
T239 2030-2074 Sentence denotes AC −4.63 −5.21 −3.02 −3.49 −5.38 −2.32 −3.78
T240 2075-2117 Sentence denotes APL 13.35 13.40 9.96 6.49 10.66 4.59 11.17
T241 2118-2163 Sentence denotes CoC −1.44 −1.64 −1.59 −1.30 −1.23 −1.15 −1.25
T242 2164-2209 Sentence denotes ClC −6.24 −6.46 −6.45 −6.36 −5.88 −6.46 −6.52
T243 2210-2395 Sentence denotes Average connectivity (AC), Connection centrality (CoC), Closeness centrality (ClC): the larger the quotient is, the more stable the network and, the less the influence made by the drug.
T244 2396-2571 Sentence denotes Disturbance total score (DTS), Average length of shortest path (APL), : the larger the quotient is, the less stable the network and, the larger the influence made by the drug.
T245 2572-2603 Sentence denotes Negative control formula: BXTM.
T246 2604-2635 Sentence denotes Positive control formula: YDBF.
T247 2636-3051 Sentence denotes M3 (Fig. 8A), a specific compound in formulae MXSG, showed eight interactions with E protein [ion channel] including Pi-sigma, Pi-alkyl and Alkyl, which were connected with TYR 57, ALA 32, ILE 46 and PRO 54, etc.; additionally, M3 (Fig. 8B) showed five interactions with nsp13 [Helicase NCB site] including Unfavorable Donor-Donor, Pi-alkyl and Alkyl, which were connected with ASN 559, ARG 409, LEU 42 and PRO 406.
T248 3052-3500 Sentence denotes S1 (Fig. 8C), a specific compound in formulae SGMH, showed seven interactions with nsp13 [Helicase ADP site] including H-bond interactions, van der waals, Amide-Pi stacked and Pi-alkyl, which were connected with ALA 313, ASP 374, GLN 537 and SER 289, etc.; additionally, S1 (Fig. 8D) showed five interactions with PLpro including Pi-anion, Pi-Pi stacked, Pi-Pi T-shaped and Pi-alkyl, which were connected with TYR 264, ASP 164, TYR 268 and PRO 248.
T249 3501-3725 Sentence denotes X2 (Fig. 8E), a specific compound in formulae XCH, showed seven interactions with Mpro including H-bond interactions, Pi-Donor hydrogen bond and Pi-alkyl, which were connected with MET 165, GLU 166, LEU 141 and CYS 145, etc.
T250 3726-3971 Sentence denotes O2 (Fig. 8F), a specific compound in formulae Others, showed seven interactions with Mpro including H-bond interactions, Carbon hydrogen bond, Pi-anion, Pi-sulfur and Pi-alkyl, which were connected with MET 131, GLY 71, LEU 100 and CYS 115, etc.
T251 3972-4425 Sentence denotes MS1 (Fig. 9 A), a compound in formulae MXSG and SGMH, showed eleven interactions with N protein NCB site including H-bond interactions, Pi-Donor hydrogen bond, Pi-sigma, Pi-Pi stacked and Pi-alkyl, which were connected with SER 51, THR 109, ALA 50 and PRO 42, etc.; additionally, MS1 (Fig. 9B) showed five interactions with nsp14 [ExoN] including H-bond interactions and Pi-Pi stacked, which were connected with GLU 92, PHE 190, ASP 273 and VAL 91, etc.
T252 4426-4655 Sentence denotes MX16 (Fig. 9C), a compound in formulae MXSG and XCH, showed seven interactions with nsp15 [endoribonuclease] including H-bond interactions, Alkyl and Pi-alkyl, which were connected with PRO 343, VAL 275, LYS 344 and SER 293, etc.
T253 4656-5025 Sentence denotes SX1 (Fig. 9D), a compound in formulae SGMH and XCH, showed two interactions with nsp14 [N7-MTase] including Pi-Pi stacked and Pi-alkyl, which were connected with PHE 426; additionally, SX1 (Fig. 9E) showed five interactions with nsp15 [endoribonuclease] including H-bond interactions, Alkyl and Pi-alkyl, which were connected with LYS 344, LYS 289, VAL 291 and PRO 343.
T254 5026-5546 Sentence denotes WO1 (Fig. 9F), a compound in formulae WLS and Others, showed seven interactions with nsp16 [2′-O-MTase] including H-bond interactions, Carbon hydrogen bond, Pi-Pi T-shaped, Pi-alkyl and Pi-anion, which were connected with PHE 149, CYS 115, ASP 99 and SER 74, etc.; additionally, WO1 (Fig. 9G) showed seven interactions with nsp12 [RdRp without RNA] including H-bond interactions, Carbon hydrogen bond, Unfavorable Donor-Donor, Pi-cation and Pi-anion, which were connected with THR 556, ARG 553, ASP 623 and SER 682, etc.
T255 5547-5805 Sentence denotes XO1 (Fig. 9H), a compound in formulae XCH and Others, showed ten interactions with nsp12 [RdRp with RNA] including H-bond interactions, Pi-Donor hydrogen bond, Pi-Pi T-shaped and Pi-alkyl, which were connected with CYS 813, GLY 590, LYS 593 and ASP 865, etc.
T256 5806-5935 Sentence denotes Fig. 9 Schematic (3D and 2D) representation that molecular model of common compounds of the five formulae with COVID-19 proteins.
T257 5936-6197 Sentence denotes A: MS1 and N protein NCB site, B: MS1 and nsp14 [ExoN], C: MX16 and nsp15 [endoribonuclease], D: SX1 and nsp14 [N7-MTase], E: SX1 and nsp15 [endoribonuclease], F: WO1 and nsp16 [2′-O-MTase], G: WO1 and nsp12 [RdRp without RNA], H: XO1 and nsp12 [RdRp with RNA].
T258 6198-6292 Sentence denotes MS: MXSG and SGMH, MX: MXSG and XCH, SX: SGMH and XCH, WO: WLS and Others, XO: XCH and Others.

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T3 209-212 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T4 5026-5029 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T5 5305-5308 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T6 6099-6102 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T7 6130-6133 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690