PMC:7247521 / 26633-27158 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"361","span":{"begin":26,"end":30},"obj":"Gene"},{"id":"364","span":{"begin":119,"end":124},"obj":"Species"},{"id":"365","span":{"begin":175,"end":178},"obj":"Species"},{"id":"367","span":{"begin":5,"end":7},"obj":"Chemical"},{"id":"368","span":{"begin":89,"end":93},"obj":"Chemical"},{"id":"370","span":{"begin":79,"end":87},"obj":"Disease"},{"id":"371","span":{"begin":185,"end":193},"obj":"Disease"},{"id":"372","span":{"begin":206,"end":220},"obj":"Disease"},{"id":"373","span":{"begin":226,"end":244},"obj":"Disease"},{"id":"374","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"388","span":{"begin":507,"end":515},"obj":"Disease"}],"attributes":[{"id":"A361","pred":"tao:has_database_id","subj":"361","obj":"Gene:6582"},{"id":"A364","pred":"tao:has_database_id","subj":"364","obj":"Tax:9606"},{"id":"A365","pred":"tao:has_database_id","subj":"365","obj":"Tax:10116"},{"id":"A367","pred":"tao:has_database_id","subj":"367","obj":"MESH:D013667"},{"id":"A370","pred":"tao:has_database_id","subj":"370","obj":"MESH:D064420"},{"id":"A371","pred":"tao:has_database_id","subj":"371","obj":"MESH:D064420"},{"id":"A372","pred":"tao:has_database_id","subj":"372","obj":"MESH:D056486"},{"id":"A373","pred":"tao:has_database_id","subj":"373","obj":"MESH:D012871"},{"id":"A374","pred":"tao:has_database_id","subj":"374","obj":"MESH:D064420"},{"id":"A388","pred":"tao:has_database_id","subj":"388","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T299","span":{"begin":26,"end":30},"obj":"PR:000013036"},{"id":"T300","span":{"begin":32,"end":37},"obj":"UBERON:0002113"},{"id":"T301","span":{"begin":38,"end":52},"obj":"CHEBI:25697;CHEBI:25697;PR:000014988"},{"id":"T302","span":{"begin":53,"end":66},"obj":"PR:000014988"},{"id":"T303","span":{"begin":119,"end":124},"obj":"SP_6;NCBITaxon:9606"},{"id":"T304","span":{"begin":127,"end":131},"obj":"PR:P11308"},{"id":"T305","span":{"begin":138,"end":142},"obj":"PR:P11308"},{"id":"T306","span":{"begin":170,"end":174},"obj":"UBERON:0000165"},{"id":"T307","span":{"begin":175,"end":178},"obj":"NCBITaxon:10114"},{"id":"T308","span":{"begin":246,"end":248},"obj":"UBERON:0001448"},{"id":"T309","span":{"begin":475,"end":484},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T310","span":{"begin":507,"end":515},"obj":"SP_7"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T82","span":{"begin":226,"end":230},"obj":"Body_part"},{"id":"T83","span":{"begin":516,"end":524},"obj":"Body_part"}],"attributes":[{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma7163"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":226,"end":230},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000014"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T59","span":{"begin":507,"end":515},"obj":"Disease"}],"attributes":[{"id":"A59","pred":"mondo_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T201","span":{"begin":38,"end":45},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T202","span":{"begin":38,"end":45},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T203","span":{"begin":119,"end":124},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T204","span":{"begin":202,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0004265"},{"id":"T205","span":{"begin":226,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0000014"},{"id":"T206","span":{"begin":226,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0001003"},{"id":"T207","span":{"begin":226,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0002097"},{"id":"T208","span":{"begin":226,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0002199"},{"id":"T209","span":{"begin":226,"end":230},"obj":"http://www.ebi.ac.uk/efo/EFO_0000962"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T152","span":{"begin":46,"end":52},"obj":"Chemical"},{"id":"T153","span":{"begin":134,"end":136},"obj":"Chemical"},{"id":"T154","span":{"begin":149,"end":151},"obj":"Chemical"},{"id":"T155","span":{"begin":222,"end":224},"obj":"Chemical"},{"id":"T156","span":{"begin":246,"end":248},"obj":"Chemical"},{"id":"T157","span":{"begin":516,"end":524},"obj":"Chemical"}],"attributes":[{"id":"A152","pred":"chebi_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/CHEBI_36916"},{"id":"A153","pred":"chebi_id","subj":"T153","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A154","pred":"chebi_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A155","pred":"chebi_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/CHEBI_73653"},{"id":"A156","pred":"chebi_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/CHEBI_73614"},{"id":"A157","pred":"chebi_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T97","span":{"begin":38,"end":64},"obj":"http://purl.obolibrary.org/obo/GO_0015695"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}

{"project":"LitCovid-sentences","denotations":[{"id":"T185","span":{"begin":9,"end":31},"obj":"Sentence"},{"id":"T186","span":{"begin":32,"end":94},"obj":"Sentence"},{"id":"T187","span":{"begin":95,"end":169},"obj":"Sentence"},{"id":"T188","span":{"begin":170,"end":205},"obj":"Sentence"},{"id":"T189","span":{"begin":206,"end":225},"obj":"Sentence"},{"id":"T190","span":{"begin":226,"end":249},"obj":"Sentence"},{"id":"T191","span":{"begin":250,"end":397},"obj":"Sentence"},{"id":"T192","span":{"begin":398,"end":525},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)\nFig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins."}