lity,TC: Total Clearance, OCT2: Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD: Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50: Oral Rat Acute Toxicity (LD50), HT: Hepatotoxicity, SS: Skin Sensitisation, MT: Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Fig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins.