PMC:7247521 / 22684-23245 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"310","span":{"begin":250,"end":255},"obj":"Gene"},{"id":"311","span":{"begin":322,"end":326},"obj":"Gene"},{"id":"312","span":{"begin":393,"end":398},"obj":"Gene"},{"id":"313","span":{"begin":475,"end":482},"obj":"Gene"}],"attributes":[{"id":"A310","pred":"tao:has_database_id","subj":"310","obj":"Gene:84532"},{"id":"A311","pred":"tao:has_database_id","subj":"311","obj":"Gene:1269"},{"id":"A312","pred":"tao:has_database_id","subj":"312","obj":"Gene:5582"},{"id":"A313","pred":"tao:has_database_id","subj":"313","obj":"Gene:3630"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T251","span":{"begin":35,"end":40},"obj":"SO:0001867"},{"id":"T252","span":{"begin":241,"end":245},"obj":"SO:0000704"},{"id":"T253","span":{"begin":250,"end":255},"obj":"PR:000003671"},{"id":"T254","span":{"begin":313,"end":317},"obj":"SO:0000704"},{"id":"T255","span":{"begin":322,"end":326},"obj":"PR:000001126"},{"id":"T256","span":{"begin":384,"end":388},"obj":"SO:0000704"},{"id":"T257","span":{"begin":450,"end":457},"obj":"SO:0000417"},{"id":"T258","span":{"begin":475,"end":482},"obj":"PR:000009054"},{"id":"T259","span":{"begin":509,"end":518},"obj":"GO:0019221"},{"id":"T260","span":{"begin":528,"end":532},"obj":"CL:0000899"},{"id":"T261","span":{"begin":533,"end":537},"obj":"CL:0000899;GO:0030154"},{"id":"T262","span":{"begin":538,"end":553},"obj":"GO:0030154"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T59","span":{"begin":241,"end":245},"obj":"Body_part"},{"id":"T60","span":{"begin":313,"end":317},"obj":"Body_part"},{"id":"T61","span":{"begin":384,"end":388},"obj":"Body_part"},{"id":"T62","span":{"begin":475,"end":482},"obj":"Body_part"},{"id":"T63","span":{"begin":533,"end":537},"obj":"Body_part"}],"attributes":[{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A61","pred":"fma_id","subj":"T61","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A62","pred":"fma_id","subj":"T62","obj":"http://purl.org/sig/ont/fma/fma83365"},{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T146","span":{"begin":35,"end":40},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T147","span":{"begin":241,"end":245},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T148","span":{"begin":313,"end":317},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T149","span":{"begin":384,"end":388},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T150","span":{"begin":475,"end":482},"obj":"http://purl.obolibrary.org/obo/PR_000009054"},{"id":"T151","span":{"begin":509,"end":518},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T152","span":{"begin":533,"end":537},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T128","span":{"begin":66,"end":69},"obj":"Chemical"},{"id":"T130","span":{"begin":475,"end":482},"obj":"Chemical"}],"attributes":[{"id":"A128","pred":"chebi_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/CHEBI_53266"},{"id":"A129","pred":"chebi_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/CHEBI_60614"},{"id":"A130","pred":"chebi_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/CHEBI_145810"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T15","span":{"begin":475,"end":493},"obj":"Phenotype"}],"attributes":[{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0000855"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T86","span":{"begin":495,"end":526},"obj":"http://purl.obolibrary.org/obo/GO_0033211"},{"id":"T87","span":{"begin":495,"end":526},"obj":"http://purl.obolibrary.org/obo/GO_0033210"},{"id":"T88","span":{"begin":495,"end":526},"obj":"http://purl.obolibrary.org/obo/GO_0033209"},{"id":"T89","span":{"begin":509,"end":526},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T90","span":{"begin":509,"end":518},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T91","span":{"begin":533,"end":553},"obj":"http://purl.obolibrary.org/obo/GO_0030154"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}

{"project":"LitCovid-sentences","denotations":[{"id":"T142","span":{"begin":0,"end":142},"obj":"Sentence"},{"id":"T143","span":{"begin":143,"end":181},"obj":"Sentence"},{"id":"T144","span":{"begin":182,"end":198},"obj":"Sentence"},{"id":"T145","span":{"begin":199,"end":273},"obj":"Sentence"},{"id":"T146","span":{"begin":274,"end":344},"obj":"Sentence"},{"id":"T147","span":{"begin":345,"end":399},"obj":"Sentence"},{"id":"T148","span":{"begin":400,"end":561},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges. 3 modules scores were \u003e 2.5 (Fig. 5D). Module 1 (score: 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score: 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score: 3.5) consisted of 8 nodes and the seed gene was PRKCG. KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al."}