PMC:7247521 / 13859-14999 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7247521","sourcedb":"PMC","sourceid":"7247521","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7247521","text":"control.\n\n3 Result\n\n3.1 Prediction of active components and potential targets of QFPD\nFirstly, the DL ≥ 0.18 and OB ≥ 30 %.s were set as the standard to screen the chemical components obtained through online database TCMSP. Specifically, a total of 175 effective components of QFPD were screened from the TCM database, including 82 species of MSXG, 35 species of SGMH, 105 species of XCH, 21 species of WLS and 32 species of Others (Table 1 ). Among these effective components, 89 (50.86 %) components exited in more than two formulae; CID5280343 and CID5280794 were owned by MXSG, Others, SGMH and XCH; CID12303645 was owned by MXSG, Others, WLS and XCH (Fig. 1 A). Secondly, a total of 300 targets of QFPD were screened from the BATMAN-TCM database, including 192 targets of MSXG, 201 targets of SGMH, 221 targets of XCH, 96 targets of WLS and 99 targets of Others. Among these proteins, 21 (7%) targets exited in five formulae (Fig. 1B).\nTable 1 Effective components of QFPD.\nFormula N PubChem_Cid\nMSXG 82 CID10090416,CID10542808,CID10881804,CID11267805,CID114829,CID11558452,CID11602329,CID11975273,CID120074,CID12303645,CID124049,CID","divisions":[{"label":"label","span":{"begin":10,"end":11}},{"label":"title","span":{"begin":13,"end":19}},{"label":"label","span":{"begin":21,"end":24}},{"label":"title","span":{"begin":26,"end":87}},{"label":"label","span":{"begin":943,"end":950}},{"label":"caption","span":{"begin":951,"end":980}},{"label":"p","span":{"begin":951,"end":980}},{"label":"tr","span":{"begin":981,"end":1002}},{"label":"th","span":{"begin":981,"end":988}},{"label":"th","span":{"begin":989,"end":990}},{"label":"th","span":{"begin":991,"end":1002}},{"label":"td","span":{"begin":1003,"end":1007}},{"label":"td","span":{"begin":1008,"end":1010}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"235","span":{"begin":115,"end":117},"obj":"Disease"},{"id":"236","span":{"begin":386,"end":389},"obj":"Disease"},{"id":"237","span":{"begin":601,"end":604},"obj":"Disease"},{"id":"238","span":{"begin":653,"end":656},"obj":"Disease"},{"id":"239","span":{"begin":821,"end":824},"obj":"Disease"}],"attributes":[{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"MESH:D009765"},{"subj":"235","pred":"source","obj":"LitCovid-PubTator"},{"subj":"236","pred":"source","obj":"LitCovid-PubTator"},{"subj":"237","pred":"source","obj":"LitCovid-PubTator"},{"subj":"238","pred":"source","obj":"LitCovid-PubTator"},{"subj":"239","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T38","span":{"begin":882,"end":890},"obj":"Body_part"}],"attributes":[{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T97","span":{"begin":40,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T98","span":{"begin":240,"end":241},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T99","span":{"begin":351,"end":353},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T100","span":{"begin":665,"end":666},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T101","span":{"begin":679,"end":680},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T97","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T71","span":{"begin":101,"end":103},"obj":"Chemical"},{"id":"T72","span":{"begin":307,"end":310},"obj":"Chemical"},{"id":"T73","span":{"begin":740,"end":743},"obj":"Chemical"},{"id":"T74","span":{"begin":882,"end":890},"obj":"Chemical"}],"attributes":[{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_68596"},{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_145500"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_145500"},{"id":"A74","pred":"chebi_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T85","span":{"begin":10,"end":19},"obj":"Sentence"},{"id":"T86","span":{"begin":21,"end":87},"obj":"Sentence"},{"id":"T87","span":{"begin":88,"end":225},"obj":"Sentence"},{"id":"T88","span":{"begin":226,"end":445},"obj":"Sentence"},{"id":"T89","span":{"begin":446,"end":668},"obj":"Sentence"},{"id":"T90","span":{"begin":669,"end":869},"obj":"Sentence"},{"id":"T91","span":{"begin":870,"end":942},"obj":"Sentence"},{"id":"T92","span":{"begin":943,"end":980},"obj":"Sentence"},{"id":"T93","span":{"begin":981,"end":1002},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T85","pred":"source","obj":"LitCovid-sentences"},{"subj":"T86","pred":"source","obj":"LitCovid-sentences"},{"subj":"T87","pred":"source","obj":"LitCovid-sentences"},{"subj":"T88","pred":"source","obj":"LitCovid-sentences"},{"subj":"T89","pred":"source","obj":"LitCovid-sentences"},{"subj":"T90","pred":"source","obj":"LitCovid-sentences"},{"subj":"T91","pred":"source","obj":"LitCovid-sentences"},{"subj":"T92","pred":"source","obj":"LitCovid-sentences"},{"subj":"T93","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attrib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