PMC:7247521 / 11511-12238 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"190","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"191","span":{"begin":14,"end":19},"obj":"Gene"},{"id":"198","span":{"begin":119,"end":123},"obj":"Gene"},{"id":"199","span":{"begin":128,"end":133},"obj":"Gene"},{"id":"200","span":{"begin":261,"end":265},"obj":"Gene"},{"id":"201","span":{"begin":270,"end":275},"obj":"Gene"},{"id":"202","span":{"begin":493,"end":497},"obj":"Gene"},{"id":"203","span":{"begin":385,"end":394},"obj":"Disease"}],"attributes":[{"id":"A190","pred":"tao:has_database_id","subj":"190","obj":"Gene:59272"},{"id":"A191","pred":"tao:has_database_id","subj":"191","obj":"Gene:682"},{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"Gene:59272"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"Gene:682"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"Gene:59272"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"Gene:682"},{"id":"A202","pred":"tao:has_database_id","subj":"202","obj":"Gene:59272"},{"id":"A203","pred":"tao:has_database_id","subj":"203","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T134","span":{"begin":5,"end":9},"obj":"G_3;PG_10;PR:000003622"},{"id":"T135","span":{"begin":14,"end":19},"obj":"PR:000001324"},{"id":"T136","span":{"begin":20,"end":30},"obj":"GO:0010467"},{"id":"T137","span":{"begin":38,"end":45},"obj":"UBERON:0000479"},{"id":"T138","span":{"begin":53,"end":63},"obj":"GO:0010467"},{"id":"T139","span":{"begin":64,"end":69},"obj":"SO:0000704"},{"id":"T140","span":{"begin":88,"end":98},"obj":"GO:0010467"},{"id":"T141","span":{"begin":119,"end":123},"obj":"G_3;PG_10;PR:000003622"},{"id":"T142","span":{"begin":128,"end":133},"obj":"PR:000001324"},{"id":"T143","span":{"begin":141,"end":148},"obj":"UBERON:0000479"},{"id":"T144","span":{"begin":176,"end":183},"obj":"UBERON:0000479"},{"id":"T145","span":{"begin":241,"end":251},"obj":"GO:0010467"},{"id":"T146","span":{"begin":252,"end":257},"obj":"SO:0000704"},{"id":"T147","span":{"begin":261,"end":265},"obj":"G_3;PG_10;PR:000003622"},{"id":"T148","span":{"begin":270,"end":275},"obj":"PR:000001324"},{"id":"T149","span":{"begin":406,"end":411},"obj":"SO:0000704"},{"id":"T150","span":{"begin":473,"end":483},"obj":"GO:0010467"},{"id":"T151","span":{"begin":484,"end":489},"obj":"SO:0000704"},{"id":"T152","span":{"begin":493,"end":497},"obj":"G_3;PG_10;PR:000003622"},{"id":"T153","span":{"begin":501,"end":508},"obj":"UBERON:0001155;CL:0011108"},{"id":"T154","span":{"begin":509,"end":519},"obj":"CL:0011108;UBERON:0000483"},{"id":"T155","span":{"begin":520,"end":525},"obj":"CL:0011108"},{"id":"T156","span":{"begin":551,"end":555},"obj":"GO:0018995"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T30","span":{"begin":38,"end":45},"obj":"Body_part"},{"id":"T31","span":{"begin":141,"end":148},"obj":"Body_part"},{"id":"T32","span":{"begin":176,"end":183},"obj":"Body_part"},{"id":"T33","span":{"begin":509,"end":525},"obj":"Body_part"},{"id":"T34","span":{"begin":520,"end":525},"obj":"Body_part"},{"id":"T35","span":{"begin":556,"end":564},"obj":"Body_part"},{"id":"T36","span":{"begin":701,"end":709},"obj":"Body_part"}],"attributes":[{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T38","span":{"begin":385,"end":394},"obj":"Disease"}],"attributes":[{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T87","span":{"begin":64,"end":69},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T88","span":{"begin":150,"end":151},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T89","span":{"begin":252,"end":257},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T90","span":{"begin":406,"end":411},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T91","span":{"begin":484,"end":489},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T92","span":{"begin":501,"end":508},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T93","span":{"begin":509,"end":519},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T94","span":{"begin":520,"end":525},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T61","span":{"begin":556,"end":564},"obj":"Chemical"},{"id":"T62","span":{"begin":701,"end":709},"obj":"Chemical"}],"attributes":[{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T10","span":{"begin":385,"end":394},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-sentences","denotations":[{"id":"T70","span":{"begin":0,"end":69},"obj":"Sentence"},{"id":"T71","span":{"begin":70,"end":221},"obj":"Sentence"},{"id":"T72","span":{"begin":222,"end":316},"obj":"Sentence"},{"id":"T73","span":{"begin":317,"end":456},"obj":"Sentence"},{"id":"T74","span":{"begin":457,"end":600},"obj":"Sentence"},{"id":"T75","span":{"begin":601,"end":727},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"2_test","denotations":[{"id":"32554251-30462320-6393502","span":{"begin":217,"end":219},"obj":"30462320"}],"text":"2.7 ACE2 and CD147 expression across tissues and co-expression genes\nTo understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}