PMC:7247521 / 10622-11509 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
176	307-311	Gene	denotes	Mpro	Gene:8673700
177	327-331	Gene	denotes	RdRp	Gene:43740578
178	350-354	Gene	denotes	RdRp	Gene:43740578
179	376-384	Gene	denotes	Helicase	Gene:164045
180	403-411	Gene	denotes	Helicase	Gene:164045
181	313-318	Gene	denotes	PLpro	Gene:43740578
182	88-92	Species	denotes	ncov	Tax:2697049
183	281-290	Species	denotes	2019-nCov	Tax:2697049
184	37-45	Disease	denotes	COVID-19	MESH:C000657245
185	55-63	Disease	denotes	COVID-19	MESH:C000657245
186	166-174	Disease	denotes	COVID-19	MESH:C000657245
187	862-870	Disease	denotes	COVID-19	MESH:C000657245

Id	Subject	Object	Predicate	Lexical cue
T114	14-18	CHEBI:23888;CHEBI:23888	denotes	drug
T115	37-45	SP_7	denotes	COVID-19
T116	55-63	SP_7	denotes	COVID-19
T117	166-174	SP_7	denotes	COVID-19
T118	281-290	SP_7	denotes	2019-nCov
T119	320-325	PR:000000125	denotes	nsp12
T120	343-348	PR:000000125	denotes	nsp12
T121	369-374	PR:000000125	denotes	nsp13
T122	385-393	SO:0000346	denotes	ADP site
T123	396-401	PR:000000125	denotes	nsp13
T124	423-428	PR:000000125	denotes	nsp14
T125	437-442	PR:000000125	denotes	nsp14
T126	455-460	PR:000000125	denotes	nsp15
T127	481-486	PR:000000125	denotes	nsp16
T128	501-510	PG_4	denotes	N protein
T129	524-533	PG_2	denotes	E protein
T130	535-538	CHEBI:24870;CHEBI:24870	denotes	ion
T131	665-669	SO:0000346	denotes	site
T132	844-853	CHEBI:36357;CHEBI:36357	denotes	compounds
T133	862-870	SP_7	denotes	COVID-19

Id	Subject	Object	Predicate	Lexical cue	fma_id
T19	269-277	Body_part	denotes	proteins	http://purl.org/sig/ont/fma/fma67257
T20	337-340	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T21	363-366	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T22	430-434	Body_part	denotes	ExoN	http://purl.org/sig/ont/fma/fma84120
T23	503-510	Body_part	denotes	protein	http://purl.org/sig/ont/fma/fma67257
T24	526-533	Body_part	denotes	protein	http://purl.org/sig/ont/fma/fma67257
T25	572-579	Body_part	denotes	Protein	http://purl.org/sig/ont/fma/fma67257
T26	629-632	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T27	649-652	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T28	695-699	Body_part	denotes	ExoN	http://purl.org/sig/ont/fma/fma84120
T29	878-886	Body_part	denotes	proteins	http://purl.org/sig/ont/fma/fma67257

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T34	37-45	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T35	55-63	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T36	166-174	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T37	862-870	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096

Id	Subject	Object	Predicate	Lexical cue	chebi_id
T48	14-18	Chemical	denotes	drug	http://purl.obolibrary.org/obo/CHEBI_23888
T49	269-277	Chemical	denotes	proteins	http://purl.obolibrary.org/obo/CHEBI_36080
T50	385-388	Chemical	denotes	ADP	http://purl.obolibrary.org/obo/CHEBI_16761\|http://purl.obolibrary.org/obo/CHEBI_456216\|http://purl.obolibrary.org/obo/CHEBI_73342
T53	503-510	Chemical	denotes	protein	http://purl.obolibrary.org/obo/CHEBI_36080
T54	526-533	Chemical	denotes	protein	http://purl.obolibrary.org/obo/CHEBI_36080
T55	535-538	Chemical	denotes	ion	http://purl.obolibrary.org/obo/CHEBI_24870
T56	572-579	Chemical	denotes	Protein	http://purl.obolibrary.org/obo/CHEBI_16541
T57	661-664	Chemical	denotes	ADP	http://purl.obolibrary.org/obo/CHEBI_16761\|http://purl.obolibrary.org/obo/CHEBI_456216\|http://purl.obolibrary.org/obo/CHEBI_73342
T60	878-886	Chemical	denotes	proteins	http://purl.obolibrary.org/obo/CHEBI_36080

Id	Subject	Object	Predicate	Lexical cue
T29	535-546	http://purl.obolibrary.org/obo/GO_0022831	denotes	ion channel

Id	Subject	Object	Predicate	Lexical cue
T67	0-216	Sentence	denotes	To facilitate drug discovery against COVID-19, we used COVID-19 Docking Server (https://ncov.schanglab.org.cn/index.php) [23] to predict the binding modes between 12 COVID-19 targets and the 20 lead-likeness of QFPD.
T68	217-761	Sentence	denotes	Specifically, the 10 nonstructural and 2 structural proteins of 2019-nCov were collected (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site and E protein [ion channel]); and the corresponding Protein Data Bank (PDB)codes were 6LU7, 4OW0, 3H5Y (with RNA), 3H5Y (without RNA), 6JYT (ADP site), 6JYT (NCB site), 5C8S (ExoN),5C8S (N7-MTase), 2RHB, 2XYR, 4KYJ, and 5 × 29, respectively.
T69	762-887	Sentence	denotes	Finally, Discovery Studio software elucidated the 14 best docking results between compounds and the COVID-19 target proteins.