PMC:7243778 / 21888-22770
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7243778","sourcedb":"PMC","sourceid":"7243778","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7243778","text":"The novel SARS-CoV-2 coronavirus, first appeared in Wuhan, China, in December 2019, is creating a pandemic over the world with the number of confirmed cases reached 3,529,408, of which 248,025 were dead up to the 4th May 2020 [1]. Phylogenetic analysis of SARS-CoV-2 demonstrated similarity with SARS-CoV and bat-derived SARS-like coronaviruses (SL-CoVs) with 79.6% and 88% sequence identity, respectively. They belong to lineage B of the beta coronavirus genus [73,74]. SARS-CoV-2 seems to be more contagious but less pathogenic than SARS-CoV [75]. COVID-19 is a self-limiting disease in \u003e80% of patients. Same as Spanish influenza viruses, SARS-CoV and SARS-CoV-2 induce a “cytokine storm” but to different degrees. 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