PMC:7243768 / 62296-63897
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
2381 | 1238-1243 | Gene | denotes | IFN-β | Gene:3439 |
2382 | 280-288 | Species | denotes | SARS-CoV | Tax:694009 |
2383 | 365-373 | Species | denotes | SARS-CoV | Tax:694009 |
2384 | 579-587 | Species | denotes | SARS-CoV | Tax:694009 |
2385 | 848-856 | Species | denotes | SARS-CoV | Tax:694009 |
2386 | 858-866 | Species | denotes | MERS-CoV | Tax:1335626 |
2387 | 868-878 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
2388 | 950-958 | Species | denotes | MERS-CoV | Tax:1335626 |
2389 | 960-970 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
2390 | 1135-1143 | Species | denotes | MERS-CoV | Tax:1335626 |
2391 | 1244-1252 | Species | denotes | MERS-CoV | Tax:1335626 |
2392 | 1411-1421 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
2393 | 90-98 | Species | denotes | SARS-CoV | Tax:694009 |
2394 | 459-467 | Species | denotes | SARS-CoV | Tax:694009 |
2395 | 80-89 | Chemical | denotes | Ribavirin | MESH:D012254 |
2396 | 110-120 | Chemical | denotes | nucleoside | MESH:D009705 |
2397 | 270-279 | Chemical | denotes | Lopinavir | MESH:D061466 |
2398 | 355-364 | Chemical | denotes | Ritonavir | MESH:D019438 |
2399 | 440-458 | Chemical | denotes | Methylprednisolone | MESH:D008775 |
2400 | 674-692 | Chemical | denotes | Methylprednisolone | MESH:D008775 |
2401 | 719-733 | Chemical | denotes | hydrocortisone | MESH:D006854 |
2402 | 766-784 | Chemical | denotes | methylprednisolone | MESH:D008775 |
2403 | 930-949 | Chemical | denotes | Lopinavir/ritonavir | MESH:C558899 |
2404 | 1214-1233 | Chemical | denotes | Lopinavir/ritonavir | MESH:C558899 |
2405 | 1392-1410 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
2406 | 169-175 | Disease | denotes | Anemia | MESH:D000740 |
2407 | 177-189 | Disease | denotes | hypocalcemia | MESH:D006996 |
2408 | 191-205 | Disease | denotes | hypomagnesemia | MESH:C537153 |
2409 | 248-259 | Disease | denotes | bradycardia | MESH:D001919 |
2410 | 309-317 | Disease | denotes | Diarrhea | MESH:D003967 |
2411 | 319-325 | Disease | denotes | nausea | MESH:D009325 |
2412 | 327-335 | Disease | denotes | vomiting | MESH:D014839 |
2413 | 337-345 | Disease | denotes | headache | MESH:D006261 |
2414 | 394-402 | Disease | denotes | Diarrhea | MESH:D003967 |
2415 | 404-410 | Disease | denotes | nausea | MESH:D009325 |
2416 | 412-420 | Disease | denotes | vomiting | MESH:D014839 |
2417 | 422-430 | Disease | denotes | headache | MESH:D006261 |
2418 | 506-514 | Disease | denotes | diabetes | MESH:D003920 |
2419 | 516-534 | Disease | denotes | avascular necrosis | MESH:D010020 |
2420 | 536-548 | Disease | denotes | osteoporosis | MESH:D010024 |
2421 | 622-635 | Disease | denotes | Aspergillosis | MESH:D001228 |
2422 | 1022-1031 | Disease | denotes | pneumonia | MESH:D011014 |
2423 | 1042-1061 | Disease | denotes | SARS-CoV-2 Diarrhea | MESH:C000657245 |
2424 | 1063-1069 | Disease | denotes | nausea | MESH:D009325 |
2425 | 1071-1079 | Disease | denotes | vomiting | MESH:D014839 |
2426 | 1081-1089 | Disease | denotes | headache | MESH:D006261 |
2427 | 1167-1175 | Disease | denotes | Diarrhea | MESH:D003967 |
2428 | 1177-1183 | Disease | denotes | nausea | MESH:D009325 |
2429 | 1185-1193 | Disease | denotes | vomiting | MESH:D014839 |
2430 | 1195-1203 | Disease | denotes | headache | MESH:D006261 |
2431 | 1296-1304 | Disease | denotes | necrosis | MESH:D009336 |
2432 | 1341-1349 | Disease | denotes | Diarrhea | MESH:D003967 |
2433 | 1351-1357 | Disease | denotes | nausea | MESH:D009325 |
2434 | 1359-1367 | Disease | denotes | vomiting | MESH:D014839 |
2435 | 1369-1377 | Disease | denotes | headache | MESH:D006261 |
2436 | 1423-1430 | Disease | denotes | Malaria | MESH:D008288 |
2437 | 1534-1556 | Disease | denotes | infected cell Diarrhea | MESH:D003967 |
2438 | 1558-1564 | Disease | denotes | nausea | MESH:D009325 |
2439 | 1566-1574 | Disease | denotes | vomiting | MESH:D014839 |
2440 | 1576-1584 | Disease | denotes | headache | MESH:D006261 |
2441 | 1586-1595 | Disease | denotes | dizziness | MESH:D004244 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T519 | 801-805 | Body_part | denotes | Lung | http://purl.org/sig/ont/fma/fma7195 |
T520 | 841-847 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
T521 | 1153-1156 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
T522 | 1308-1313 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T523 | 1333-1340 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T524 | 1452-1460 | Body_part | denotes | endosome | http://purl.org/sig/ont/fma/fma67180 |
T525 | 1543-1547 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T260 | 801-805 | Body_part | denotes | Lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T718 | 90-98 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T719 | 90-94 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T720 | 169-175 | Disease | denotes | Anemia | http://purl.obolibrary.org/obo/MONDO_0002280 |
T721 | 177-189 | Disease | denotes | hypocalcemia | http://purl.obolibrary.org/obo/MONDO_0018543 |
T722 | 191-205 | Disease | denotes | hypomagnesemia | http://purl.obolibrary.org/obo/MONDO_0018100 |
T723 | 280-288 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T724 | 280-284 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T725 | 309-317 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T726 | 365-373 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T727 | 365-369 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T728 | 394-402 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T729 | 459-467 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T730 | 459-463 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T731 | 506-514 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
T732 | 516-534 | Disease | denotes | avascular necrosis | http://purl.obolibrary.org/obo/MONDO_0005380|http://purl.obolibrary.org/obo/MONDO_0018373 |
T734 | 536-548 | Disease | denotes | osteoporosis | http://purl.obolibrary.org/obo/MONDO_0005298 |
T735 | 579-587 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T736 | 579-583 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T737 | 622-635 | Disease | denotes | Aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
T738 | 801-814 | Disease | denotes | Lung diseases | http://purl.obolibrary.org/obo/MONDO_0005275 |
T739 | 848-856 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T740 | 848-852 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T741 | 868-876 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T742 | 868-872 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T743 | 960-968 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T744 | 960-964 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T745 | 1022-1031 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T746 | 1042-1050 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T747 | 1042-1046 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T748 | 1053-1061 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T749 | 1122-1133 | Disease | denotes | Hepatitis-C | http://purl.obolibrary.org/obo/MONDO_0005231 |
T750 | 1122-1131 | Disease | denotes | Hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
T751 | 1167-1175 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T752 | 1341-1349 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T753 | 1411-1419 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T754 | 1411-1415 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T755 | 1423-1430 | Disease | denotes | Malaria | http://purl.obolibrary.org/obo/MONDO_0005136 |
T756 | 1548-1556 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T791 | 801-805 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
T792 | 801-805 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | Lung |
T793 | 841-847 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T794 | 1308-1313 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T795 | 1388-1390 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T796 | 1543-1547 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T69397 | 110-120 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T20148 | 270-279 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T21128 | 298-308 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T81696 | 383-393 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T16278 | 719-733 | Chemical | denotes | hydrocortisone | http://purl.obolibrary.org/obo/CHEBI_17650 |
T64734 | 766-784 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
T9447 | 930-939 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T79 | 940-949 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T53974 | 1109-1119 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
T37213 | 1153-1156 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
T38671 | 1214-1223 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T55075 | 1224-1233 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T122 | 130-168 | http://purl.obolibrary.org/obo/GO_0045071 | denotes | inhibits the viral genomic replication |
T123 | 143-168 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral genomic replication |
T124 | 526-534 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T125 | 526-534 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T126 | 526-534 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T127 | 526-534 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
T128 | 899-914 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T129 | 1153-1166 | http://purl.obolibrary.org/obo/GO_0071897 | denotes | DNA synthesis |
T130 | 1157-1166 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T131 | 1296-1304 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T132 | 1296-1304 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T133 | 1296-1304 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T134 | 1296-1304 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T448 | 0-6 | Sentence | denotes | S. no. |
T449 | 7-76 | Sentence | denotes | Drug Effective against Mechanism of action Adverse effects References |
T450 | 77-79 | Sentence | denotes | 1. |
T451 | 80-266 | Sentence | denotes | Ribavirin SARS-CoV Anti-viral nucleoside analog – inhibits the viral genomic replication Anemia, hypocalcemia, hypomagnesemia, developed the risk of teratogenicity and bradycardia [118]. |
T452 | 267-269 | Sentence | denotes | 2. |
T453 | 270-351 | Sentence | denotes | Lopinavir SARS-CoV Protease inhibitors Diarrhea, nausea, vomiting, headache [122] |
T454 | 352-354 | Sentence | denotes | 3. |
T455 | 355-436 | Sentence | denotes | Ritonavir SARS-CoV Protease inhibitors Diarrhea, nausea, vomiting, headache [122] |
T456 | 437-439 | Sentence | denotes | 4. |
T457 | 440-559 | Sentence | denotes | Methylprednisolone SARS-CoV Anti-inflammatory effect The onset of diabetes, avascular necrosis, osteoporosis. [132,133] |
T458 | 560-562 | Sentence | denotes | 5. |
T459 | 563-670 | Sentence | denotes | Corticosteroids SARS-CoV Inhibits pro-inflammatory effects Aspergillosis and fungal superinfection [49,134] |
T460 | 671-673 | Sentence | denotes | 6. |
T461 | 674-824 | Sentence | denotes | Methylprednisolone (0.5–1 mg/kg) followed by hydrocortisone (100 mg/8 h) and pulse doses of methylprednisolone (0.5 g for 3 d) Lung diseases – – [124] |
T462 | 825-827 | Sentence | denotes | 7. |
T463 | 828-926 | Sentence | denotes | Convalescent plasma SARS-CoV, MERS-CoV, SARS-CoV-2 Adaptive or passive immune response – [135,139] |
T464 | 927-929 | Sentence | denotes | 8. |
T465 | 930-1095 | Sentence | denotes | Lopinavir/ritonavir MERS-CoV, SARS-CoV-2 Not effective against MERS, anti-viral therapy for pneumonia caused by SARS-CoV-2 Diarrhea, nausea, vomiting, headache [140] |
T466 | 1096-1098 | Sentence | denotes | 9. |
T467 | 1099-1209 | Sentence | denotes | Pegylated interferon-α Hepatitis-C, MERS-CoV Inhibits DNA synthesis Diarrhea, nausea, vomiting, headache [140] |
T468 | 1210-1213 | Sentence | denotes | 10. |
T469 | 1214-1387 | Sentence | denotes | Lopinavir/ritonavir and IFN-β MERS-CoV Improves pulmonary, reduce viral load, and necrosis in lungs and extrapulmonary tissues Diarrhea, nausea, vomiting, headache [143,144] |
T470 | 1388-1391 | Sentence | denotes | 11. |
T471 | 1392-1601 | Sentence | denotes | Hydroxychloroquine SARS-CoV-2, Malaria Blocks maturation of endosome, maturation and its function by inhibiting the release of virions in the infected cell Diarrhea, nausea, vomiting, headache, dizziness [112] |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T280 | 169-175 | Phenotype | denotes | Anemia | http://purl.obolibrary.org/obo/HP_0001903 |
T281 | 177-189 | Phenotype | denotes | hypocalcemia | http://purl.obolibrary.org/obo/HP_0002901 |
T282 | 191-205 | Phenotype | denotes | hypomagnesemia | http://purl.obolibrary.org/obo/HP_0002917 |
T283 | 248-259 | Phenotype | denotes | bradycardia | http://purl.obolibrary.org/obo/HP_0001662 |
T284 | 309-317 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T285 | 319-335 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T286 | 337-345 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T287 | 394-402 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T288 | 404-420 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T289 | 422-430 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T290 | 516-534 | Phenotype | denotes | avascular necrosis | http://purl.obolibrary.org/obo/HP_0010885 |
T291 | 536-548 | Phenotype | denotes | osteoporosis | http://purl.obolibrary.org/obo/HP_0000939 |
T292 | 801-814 | Phenotype | denotes | Lung diseases | http://purl.obolibrary.org/obo/HP_0002088 |
T293 | 1022-1031 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T294 | 1053-1061 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T295 | 1063-1079 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T296 | 1081-1089 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T297 | 1122-1131 | Phenotype | denotes | Hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
T298 | 1167-1175 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T299 | 1177-1193 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T300 | 1195-1203 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T301 | 1341-1349 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T302 | 1351-1367 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T303 | 1369-1377 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T304 | 1548-1556 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T305 | 1558-1574 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T306 | 1576-1584 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T307 | 1586-1595 | Phenotype | denotes | dizziness | http://purl.obolibrary.org/obo/HP_0002321 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32450165-32066541-66451116 | 432-435 | 32066541 | denotes | 122 |
32450165-15650220-66451117 | 551-554 | 15650220 | denotes | 132 |
32450165-15272286-66451118 | 663-665 | 15272286 | denotes | 49 |
32450165-14985565-66451119 | 918-921 | 14985565 | denotes | 135 |
32450165-14523782-66451120 | 922-925 | 14523782 | denotes | 139 |
32450165-16183666-66451121 | 1379-1382 | 16183666 | denotes | 143 |
32450165-15214887-66451122 | 1383-1386 | 15214887 | denotes | 144 |