PMC:7242012 / 3663-9708
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 106 | 63-94 | Gene | denotes | angiotensin‐converting enzyme 2 | Gene:59272 |
| 107 | 96-100 | Gene | denotes | ACE2 | Gene:59272 |
| 108 | 198-202 | Gene | denotes | ACE2 | Gene:59272 |
| 109 | 419-432 | Gene | denotes | interleukin‐6 | Gene:3569 |
| 110 | 434-438 | Gene | denotes | IL‐6 | Gene:3569 |
| 111 | 33-41 | Species | denotes | SARS‐CoV | Tax:694009 |
| 112 | 43-53 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 113 | 294-304 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 114 | 272-280 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 115 | 337-342 | Disease | denotes | death | MESH:D003643 |
| 128 | 1023-1031 | Species | denotes | patients | Tax:9606 |
| 129 | 542-551 | Disease | denotes | infection | MESH:D007239 |
| 130 | 564-572 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 131 | 666-674 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 132 | 679-684 | Disease | denotes | fever | MESH:D005334 |
| 133 | 703-708 | Disease | denotes | cough | MESH:D003371 |
| 134 | 806-813 | Disease | denotes | anosmia | MESH:D000857 |
| 135 | 818-825 | Disease | denotes | ageusia | MESH:D000370 |
| 136 | 859-867 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 137 | 946-957 | Disease | denotes | lymphopenia | MESH:D008231 |
| 138 | 1037-1045 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 139 | 1142-1157 | Disease | denotes | viral pneumonia | |
| 153 | 1597-1615 | Gene | denotes | C‐reactive protein | Gene:1401 |
| 154 | 1314-1322 | Species | denotes | patients | Tax:9606 |
| 155 | 1347-1352 | Disease | denotes | Fever | MESH:D005334 |
| 156 | 1363-1368 | Disease | denotes | Cough | MESH:D003371 |
| 157 | 1403-1414 | Disease | denotes | Dyspnea 19 | MESH:C000657245 |
| 158 | 1421-1428 | Disease | denotes | Fatigue | MESH:D005221 |
| 159 | 1429-1436 | Disease | denotes | Myalgia | MESH:D063806 |
| 160 | 1447-1455 | Disease | denotes | Headache | MESH:D006261 |
| 161 | 1466-1472 | Disease | denotes | Nausea | MESH:D009325 |
| 162 | 1491-1499 | Disease | denotes | Diarrhea | MESH:D003967 |
| 163 | 1565-1576 | Disease | denotes | Lymphopenia | MESH:D008231 |
| 164 | 1772-1807 | Disease | denotes | Acute respiratory distress syndrome | MESH:D012128 |
| 165 | 1817-1826 | Disease | denotes | Mortality | MESH:D003643 |
| 167 | 1189-1197 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 172 | 2583-2593 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 173 | 2318-2326 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 174 | 2498-2506 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 175 | 2869-2877 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 181 | 2889-2897 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 182 | 2946-2954 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 183 | 3001-3010 | Disease | denotes | pneumonia | MESH:D011014 |
| 184 | 3027-3034 | Disease | denotes | dyspnea | MESH:D004417 |
| 185 | 3064-3081 | Disease | denotes | pulmonary disease | MESH:D008171 |
| 207 | 3246-3249 | Species | denotes | men | Tax:9606 |
| 208 | 3269-3277 | Species | denotes | patients | Tax:9606 |
| 209 | 3378-3384 | Species | denotes | people | Tax:9606 |
| 210 | 3437-3444 | Species | denotes | persons | Tax:9606 |
| 211 | 3517-3525 | Species | denotes | patients | Tax:9606 |
| 212 | 3214-3222 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 213 | 3344-3352 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 214 | 3361-3367 | Disease | denotes | deaths | MESH:D003643 |
| 215 | 3415-3421 | Disease | denotes | Deaths | MESH:D003643 |
| 216 | 3531-3539 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 217 | 3576-3583 | Disease | denotes | obesity | MESH:D009765 |
| 218 | 3585-3597 | Disease | denotes | hypertension | MESH:D006973 |
| 219 | 3599-3607 | Disease | denotes | diabetes | MESH:D003920 |
| 220 | 3613-3635 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 221 | 3730-3738 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 222 | 3748-3761 | Disease | denotes | liver disease | MESH:D008107 |
| 223 | 3773-3782 | Disease | denotes | cirrhosis | MESH:D005355 |
| 224 | 4006-4014 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 225 | 4098-4103 | Disease | denotes | COVID | MESH:C000657245 |
| 226 | 4104-4113 | Disease | denotes | mortality | MESH:D003643 |
| 227 | 4150-4158 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 235 | 4506-4514 | Species | denotes | Patients | Tax:9606 |
| 236 | 4596-4608 | Disease | denotes | Hypertension | MESH:D006973 |
| 237 | 4617-4634 | Disease | denotes | Diabetes mellitus | MESH:D003920 |
| 238 | 4654-4676 | Disease | denotes | Cardiovascular disease | MESH:D002318 |
| 239 | 4696-4717 | Disease | denotes | Chronic renal disease | MESH:D051436 |
| 240 | 4745-4758 | Disease | denotes | liver disease | MESH:D008107 |
| 241 | 4809-4818 | Disease | denotes | Mortality | MESH:D003643 |
| 244 | 4359-4366 | Species | denotes | Persons | Tax:9606 |
| 245 | 4372-4380 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 253 | 5730-5734 | Gene | denotes | IL‐6 | Gene:3569 |
| 254 | 5597-5607 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 255 | 5876-5894 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 256 | 5898-5909 | Chemical | denotes | chloroquine | MESH:D002738 |
| 257 | 5679-5687 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 258 | 5812-5830 | Disease | denotes | cardiac arrythmias | MESH:D001145 |
| 259 | 5927-5935 | Disease | denotes | COVID‐19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T4 | 143-168 | Body_part | denotes | alveolar epithelial cells | http://purl.org/sig/ont/fma/fma62499 |
| T5 | 163-168 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T6 | 187-192 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T7 | 220-225 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T8 | 227-249 | Body_part | denotes | gastrointestinal tract | http://purl.org/sig/ont/fma/fma71132 |
| T9 | 255-262 | Body_part | denotes | kidneys | http://purl.org/sig/ont/fma/fma7203 |
| T10 | 332-336 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T11 | 402-411 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T12 | 419-432 | Body_part | denotes | interleukin‐6 | http://purl.org/sig/ont/fma/fma264829 |
| T13 | 419-430 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T14 | 452-460 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T15 | 929-938 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
| T16 | 983-990 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T17 | 1090-1095 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T18 | 1528-1538 | Body_part | denotes | Leukocytes | http://purl.org/sig/ont/fma/fma62852 |
| T19 | 1608-1615 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T20 | 1626-1633 | Body_part | denotes | Alanine | http://purl.org/sig/ont/fma/fma82749 |
| T21 | 1706-1711 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T22 | 2404-2412 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T23 | 2449-2455 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
| T24 | 2594-2597 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
| T25 | 2602-2605 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T26 | 2854-2858 | Body_part | denotes | sole | http://purl.org/sig/ont/fma/fma25000 |
| T27 | 3748-3753 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T28 | 4745-4750 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T29 | 5636-5646 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T30 | 5751-5765 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T2 | 220-225 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T3 | 452-466 | Body_part | denotes | alveolar walls | http://purl.obolibrary.org/obo/UBERON_0004894 |
| T4 | 1090-1095 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T5 | 1706-1711 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T6 | 2449-2455 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
| T7 | 3748-3753 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T8 | 4745-4750 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T39 | 33-37 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T40 | 43-47 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T41 | 272-280 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T42 | 294-298 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T43 | 542-551 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T44 | 564-572 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T45 | 666-674 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T46 | 806-813 | Disease | denotes | anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
| T47 | 859-867 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T48 | 946-957 | Disease | denotes | lymphopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
| T49 | 1037-1045 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T50 | 1142-1157 | Disease | denotes | viral pneumonia | http://purl.obolibrary.org/obo/MONDO_0006012 |
| T51 | 1148-1157 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T52 | 1189-1197 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T53 | 1491-1499 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T54 | 1565-1576 | Disease | denotes | Lymphopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
| T55 | 1772-1807 | Disease | denotes | Acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T56 | 1778-1807 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T57 | 2021-2029 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T58 | 2318-2326 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T59 | 2498-2506 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T60 | 2583-2587 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T61 | 2869-2877 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T62 | 2889-2897 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T63 | 2946-2954 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T64 | 3001-3010 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T65 | 3064-3081 | Disease | denotes | pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
| T66 | 3104-3108 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T67 | 3214-3222 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T68 | 3344-3352 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T69 | 3531-3539 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T70 | 3576-3583 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
| T71 | 3585-3597 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T72 | 3599-3607 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T73 | 3613-3635 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T74 | 3730-3738 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T75 | 3748-3761 | Disease | denotes | liver disease | http://purl.obolibrary.org/obo/MONDO_0005154 |
| T76 | 3773-3782 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
| T77 | 4006-4014 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T78 | 4150-4158 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T79 | 4372-4380 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T80 | 4580-4587 | Disease | denotes | Obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
| T81 | 4596-4608 | Disease | denotes | Hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T82 | 4617-4634 | Disease | denotes | Diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T83 | 4654-4676 | Disease | denotes | Cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T84 | 4696-4717 | Disease | denotes | Chronic renal disease | http://purl.obolibrary.org/obo/MONDO_0024327 |
| T85 | 4704-4717 | Disease | denotes | renal disease | http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240 |
| T87 | 4745-4758 | Disease | denotes | liver disease | http://purl.obolibrary.org/obo/MONDO_0005154 |
| T88 | 5074-5082 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T89 | 5679-5687 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T90 | 5927-5935 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T29 | 152-162 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T30 | 163-168 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T31 | 187-192 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T32 | 220-225 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T33 | 220-225 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T34 | 220-225 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T35 | 220-225 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T36 | 227-249 | http://purl.obolibrary.org/obo/UBERON_0005409 | denotes | gastrointestinal tract |
| T37 | 255-262 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidneys |
| T38 | 255-262 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidneys |
| T39 | 255-262 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidneys |
| T40 | 332-336 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T41 | 375-376 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T42 | 419-432 | http://purl.obolibrary.org/obo/PR_000001393 | denotes | interleukin‐6 |
| T43 | 613-617 | http://purl.obolibrary.org/obo/CLO_0053001 | denotes | 1‐14 |
| T44 | 630-636 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 2 , 7 |
| T45 | 786-789 | http://purl.obolibrary.org/obo/CL_0000990 | denotes | CDC |
| T46 | 920-921 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T47 | 1051-1052 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T48 | 1090-1095 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T49 | 1394-1396 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T50 | 1417-1419 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T51 | 1556-1558 | http://purl.obolibrary.org/obo/CLO_0001527 | denotes | 94 |
| T52 | 1706-1711 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T53 | 2338-2342 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T54 | 2344-2350 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 2 , 7 |
| T55 | 2386-2393 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T56 | 2538-2545 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T57 | 2547-2553 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 2 , 7 |
| T58 | 2567-2572 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T59 | 2652-2656 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T60 | 2788-2793 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T61 | 2910-2911 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T62 | 3140-3141 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T63 | 3411-3413 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T64 | 3473-3475 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T65 | 3641-3643 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T66 | 3679-3682 | http://purl.obolibrary.org/obo/CL_0000990 | denotes | CDC |
| T67 | 3686-3687 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T68 | 3748-3753 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T69 | 3748-3753 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T70 | 3784-3787 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T71 | 3797-3798 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T72 | 4561-4563 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T73 | 4566-4568 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T74 | 4650-4652 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T75 | 4692-4694 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T76 | 4745-4750 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T77 | 4745-4750 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T78 | 4760-4765 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 1% 1 |
| T79 | 4794-4799 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 3% 6 |
| T80 | 4889-4892 | http://purl.obolibrary.org/obo/CL_0000990 | denotes | CDC |
| T81 | 4966-4968 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T82 | 5339-5340 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T83 | 5365-5366 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T84 | 5609-5610 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T85 | 5937-5938 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T86 | 6035-6037 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T4 | 63-74 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T5 | 434-436 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T7 | 983-990 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T8 | 1608-1615 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T9 | 1626-1633 | Chemical | denotes | Alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
| T10 | 5597-5607 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T11 | 5626-5635 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T12 | 5636-5646 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T13 | 5647-5654 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
| T14 | 5730-5732 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T16 | 5876-5894 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T17 | 5898-5909 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 126-137 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T4 | 332-342 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | cell death |
| T5 | 350-359 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T6 | 350-359 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T7 | 849-854 | http://purl.obolibrary.org/obo/GO_0050909 | denotes | taste |
| T8 | 2254-2275 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | reverse transcription |
| T9 | 2262-2275 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T43 | 0-21 | Sentence | denotes | Clinical Presentation |
| T44 | 22-263 | Sentence | denotes | Similar to SARS‐CoV, SARS‐CoV‐2 binds to angiotensin‐converting enzyme 2 (ACE2) receptors for entry via endocytosis into alveolar epithelial cells, as well as other cells with ACE2 receptors in the heart, gastrointestinal tract, and kidneys. |
| T45 | 264-512 | Sentence | denotes | 2 , 4 COVID‐19 results from SARS‐CoV‐2 replication, causing early cell death (i.e., apoptosis) and provoking a storm of proinflammatory cytokines (e.g., interleukin‐6 [IL‐6]) disrupting alveolar walls with resulting fluid accumulation in alveoli. |
| T46 | 513-514 | Sentence | denotes | 4 |
| T47 | 515-624 | Sentence | denotes | The incubation period from infection to onset of COVID‐19 disease is typically 5 to 7 days (range 1‐14 days). |
| T48 | 625-719 | Sentence | denotes | 1 , 2 , 7 The most common symptoms of COVID‐19 are fever and nonproductive cough (Table 1). |
| T49 | 720-877 | Sentence | denotes | 1 , 4 , 7 , 9 The Centers for Disease Control and Prevention (CDC) recently added anosmia and ageusia, the loss of smell and taste, as COVID‐19 symptoms. |
| T50 | 878-991 | Sentence | denotes | 7 Laboratory findings are remarkable for a normal leukocyte count, lymphopenia, and elevated C‐reactive protein. |
| T51 | 992-1158 | Sentence | denotes | 1 , 6 , 8 Most hospitalized patients with COVID‐19 have a bilateral ground‐glass appearance on chest computed tomography (CT) scan consistent with viral pneumonia. |
| T52 | 1159-1244 | Sentence | denotes | Table 1 Clinical Features of COVID‐19 in Wuhan and Multiple Other Locations in China |
| T53 | 1245-1303 | Sentence | denotes | Clinical Features Wuhan, China Multiple Locations, China |
| T54 | 1304-1337 | Sentence | denotes | Number of patients 10,999 3,062 |
| T55 | 1338-1346 | Sentence | denotes | Symptoms |
| T56 | 1347-1362 | Sentence | denotes | Fever 89% 80% |
| T57 | 1363-1378 | Sentence | denotes | Cough 68% 63% |
| T58 | 1379-1402 | Sentence | denotes | Expectoration 34% 42% |
| T59 | 1403-1420 | Sentence | denotes | Dyspnea 19% 34% |
| T60 | 1421-1446 | Sentence | denotes | Fatigue/Myalgia 38% 46% |
| T61 | 1447-1465 | Sentence | denotes | Headache 14% 15% |
| T62 | 1466-1490 | Sentence | denotes | Nausea/Vomiting 5% 10% |
| T63 | 1491-1508 | Sentence | denotes | Diarrhea 4% 13% |
| T64 | 1509-1527 | Sentence | denotes | Laboratory results |
| T65 | 1528-1564 | Sentence | denotes | Leukocytes in normal range 94% 70% |
| T66 | 1565-1586 | Sentence | denotes | Lymphopenia 83% 57% |
| T67 | 1587-1625 | Sentence | denotes | Increased C‐reactive protein 61% 74% |
| T68 | 1626-1688 | Sentence | denotes | Alanine aminotransferase above upper limit of normal 21% 29% |
| T69 | 1689-1696 | Sentence | denotes | Imaging |
| T70 | 1697-1724 | Sentence | denotes | Abnormal chest CT 86% 89% |
| T71 | 1725-1771 | Sentence | denotes | Bilateral infiltrates (ground glass) 56% 76% |
| T72 | 1772-1816 | Sentence | denotes | Acute respiratory distress syndrome 6% 20% |
| T73 | 1817-1836 | Sentence | denotes | Mortality 1.4% 6% |
| T74 | 1837-1862 | Sentence | denotes | Data are from Guna et al. |
| T75 | 1863-1913 | Sentence | denotes | 1 and Centers for Disease Control and Prevention. |
| T76 | 1914-1915 | Sentence | denotes | 7 |
| T77 | 1916-2063 | Sentence | denotes | John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
| T78 | 2064-2246 | Sentence | denotes | It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |
| T79 | 2247-2343 | Sentence | denotes | Today, reverse transcription polymerase chain reaction (RT‐PCR) is the COVID‐19 diagnostic test. |
| T80 | 2344-2493 | Sentence | denotes | 2 , 7 RT‐PCR sensitivity is highest for testing bronchial alveolar lavage fluid (93%) and declines for sputum (72%) and nasal swab (63%) specimens. |
| T81 | 2494-2546 | Sentence | denotes | 10 COVID‐19 diagnosis might require repeat testing. |
| T82 | 2547-2631 | Sentence | denotes | 2 , 7 Serological tests to detect SARS‐CoV‐2 IgM and IgG antibodies are available. |
| T83 | 2632-2888 | Sentence | denotes | However, because of test sensitivity and other quality concerns, the US Food and Drug Administration (FDA; https://www.fda.gov) advises current serological tests are best used for surveillance and research, and not as the sole basis for COVID‐19 diagnosis. |
| T84 | 2889-2925 | Sentence | denotes | COVID‐19 is commonly a mild disease. |
| T85 | 2926-3109 | Sentence | denotes | Of the first 72,314 COVID‐19 disease reported in China, 81% had no or mild pneumonia, 21% had severe dyspnea and radiological evidence of pulmonary disease, and 5% progressed to SARS. |
| T86 | 3110-3193 | Sentence | denotes | 1 Individuals can be ill for a week or longer before experiencing severe symptoms. |
| T87 | 3194-3305 | Sentence | denotes | The risk for severe COVID‐19 disease is highest for men, older adults, and patients with certain comorbidities. |
| T88 | 3306-3400 | Sentence | denotes | In the United States, 80% of reported COVID‐19–related deaths are among people aged ≥65 years. |
| T89 | 3401-3462 | Sentence | denotes | 7 , 9 , 11 Deaths are rare among persons <24 years of age. |
| T90 | 3463-3655 | Sentence | denotes | 1 , 7 , 11 In the United States, most hospitalized patients with COVID‐19 have comorbid conditions, including obesity, hypertension, diabetes, and cardiovascular disease 7 , 11 (Table 2). |
| T91 | 3656-3881 | Sentence | denotes | Although listed by the CDC as a comorbid condition associated with severe COVID‐19, chronic liver disease, including cirrhosis, has not been a common comorbidity associated with hospitalization in the United States (Table 2). |
| T92 | 3882-4023 | Sentence | denotes | The high prevalence of comorbid conditions can explain, in part, African Americans’ increased risk for hospitalization with COVID‐19 disease. |
| T93 | 4024-4114 | Sentence | denotes | 5 Variable comorbidity prevalence contributes to differences in national COVID mortality. |
| T94 | 4115-4322 | Sentence | denotes | Globally, crude fatality rates for COVID‐19 range from 0.2% in Singapore, to 2.0% to 3.0% in South Korea and Germany, to 4.3% for the United States, and to 10% to 13% in Spain, Italy, and the United Kingdom. |
| T95 | 4323-4329 | Sentence | denotes | 2 , 5 |
| T96 | 4330-4403 | Sentence | denotes | Table 2 Comorbidities Among Persons With COVID‐19 Disease, United States |
| T97 | 4404-4444 | Sentence | denotes | Condition United States* New York City |
| T98 | 4445-4505 | Sentence | denotes | Not Hospitalized Hospitalized Intensive Care Hospitalized |
| T99 | 4506-4537 | Sentence | denotes | Patients 5143 1037 457 5700 |
| T100 | 4538-4579 | Sentence | denotes | One or more condition 27% 71% 78% 88% |
| T101 | 4580-4595 | Sentence | denotes | Obesity 42% |
| T102 | 4596-4616 | Sentence | denotes | Hypertension 57% |
| T103 | 4617-4653 | Sentence | denotes | Diabetes mellitus 6% 24% 32% 34% |
| T104 | 4654-4695 | Sentence | denotes | Cardiovascular disease 5% 23% 29% 18% |
| T105 | 4696-4736 | Sentence | denotes | Chronic renal disease 1% 9% 12% 0.6% |
| T106 | 4737-4774 | Sentence | denotes | Chronic liver disease 1% 1% 2% 9% |
| T107 | 4775-4808 | Sentence | denotes | Immunocompromised 3% 6% 9% 2% |
| T108 | 4809-4826 | Sentence | denotes | Mortality 21% |
| T109 | 4827-4840 | Sentence | denotes | Total 21% |
| T110 | 4841-4862 | Sentence | denotes | 1 Comorbidity 88% |
| T111 | 4863-4927 | Sentence | denotes | * Based on data from the CDC for all 50 states and territories. |
| T112 | 4928-4965 | Sentence | denotes | Otherwise, data are Richardson et al. |
| T113 | 4966-4968 | Sentence | denotes | 11 |
| T114 | 4969-5116 | Sentence | denotes | John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
| T115 | 5117-5299 | Sentence | denotes | It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |
| T116 | 5300-5533 | Sentence | denotes | The search for effective therapies and a vaccine is occurring at a remarkable pace, with at least 29 studies of therapeutic agents and 5 studies of candidate vaccines registered on ClinicalTrials.org (https://www.clinicaltrials.gov). |
| T117 | 5534-5688 | Sentence | denotes | On May 1, 2020, the FDA granted Emergency Use Authorization of remdesivir, a broad‐spectrum antiviral nucleotide prodrug for treatment of severe COVID‐19. |
| T118 | 5689-5782 | Sentence | denotes | Studies of monoclonal antibodies against IL‐6 and hyperimmune immunoglobulin are in progress. |
| T119 | 5783-5936 | Sentence | denotes | Following reports of serious cardiac arrythmias, the FDA cautioned clinicians of prescribing hydroxychloroquine or chloroquine for treatment of COVID‐19. |
| T120 | 5937-6045 | Sentence | denotes | A safe and effective vaccine, if successfully developed, probably will not be available for 12 to 18 months. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T3 | 679-684 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T4 | 689-708 | Phenotype | denotes | nonproductive cough | http://purl.obolibrary.org/obo/HP_0031246 |
| T5 | 806-813 | Phenotype | denotes | anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
| T6 | 818-825 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
| T7 | 831-844 | Phenotype | denotes | loss of smell | http://purl.obolibrary.org/obo/HP_0000458 |
| T8 | 946-957 | Phenotype | denotes | lymphopenia | http://purl.obolibrary.org/obo/HP_0001888 |
| T9 | 1148-1157 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T10 | 1347-1352 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T11 | 1363-1368 | Phenotype | denotes | Cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T12 | 1403-1410 | Phenotype | denotes | Dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
| T13 | 1421-1428 | Phenotype | denotes | Fatigue | http://purl.obolibrary.org/obo/HP_0012378 |
| T14 | 1429-1436 | Phenotype | denotes | Myalgia | http://purl.obolibrary.org/obo/HP_0003326 |
| T15 | 1447-1455 | Phenotype | denotes | Headache | http://purl.obolibrary.org/obo/HP_0002315 |
| T16 | 1466-1481 | Phenotype | denotes | Nausea/Vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
| T17 | 1491-1499 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
| T18 | 1565-1576 | Phenotype | denotes | Lymphopenia | http://purl.obolibrary.org/obo/HP_0001888 |
| T19 | 1778-1798 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T20 | 3001-3010 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T21 | 3027-3034 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
| T22 | 3576-3583 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
| T23 | 3585-3597 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T24 | 3613-3635 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T25 | 3748-3761 | Phenotype | denotes | liver disease | http://purl.obolibrary.org/obo/HP_0001392 |
| T26 | 3773-3782 | Phenotype | denotes | cirrhosis | http://purl.obolibrary.org/obo/HP_0001394 |
| T27 | 4580-4587 | Phenotype | denotes | Obesity | http://purl.obolibrary.org/obo/HP_0001513 |
| T28 | 4596-4608 | Phenotype | denotes | Hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T29 | 4617-4634 | Phenotype | denotes | Diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
| T30 | 4654-4676 | Phenotype | denotes | Cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T31 | 4745-4758 | Phenotype | denotes | liver disease | http://purl.obolibrary.org/obo/HP_0001392 |