PMC:7228307 / 59886-60294
Annnotations
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"1220","span":{"begin":56,"end":60},"obj":"Gene"},{"id":"1221","span":{"begin":184,"end":190},"obj":"Chemical"}],"attributes":[{"id":"A1220","pred":"tao:has_database_id","subj":"1220","obj":"Gene:2213"},{"id":"A1221","pred":"tao:has_database_id","subj":"1221","obj":"MESH:D011134"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T454","span":{"begin":29,"end":37},"obj":"Body_part"},{"id":"T455","span":{"begin":169,"end":172},"obj":"Body_part"}],"attributes":[{"id":"A454","pred":"fma_id","subj":"T454","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A455","pred":"fma_id","subj":"T455","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T991","span":{"begin":56,"end":58},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T992","span":{"begin":173,"end":175},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T993","span":{"begin":191,"end":194},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T994","span":{"begin":202,"end":203},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sample-PD-IDO
{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T254","span":{"begin":61,"end":69},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T255","span":{"begin":277,"end":287},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sample-Enju
{"project":"LitCovid-sample-Enju","denotations":[{"id":"T393","span":{"begin":0,"end":7},"obj":"JJ"},{"id":"T394","span":{"begin":8,"end":21},"obj":"NN"},{"id":"T395","span":{"begin":22,"end":24},"obj":"IN"},{"id":"T396","span":{"begin":25,"end":28},"obj":"WRB"},{"id":"T397","span":{"begin":29,"end":37},"obj":"NN"},{"id":"T398","span":{"begin":38,"end":47},"obj":"NN"},{"id":"T399","span":{"begin":48,"end":55},"obj":"VBZ"},{"id":"T400","span":{"begin":56,"end":60},"obj":"NN"},{"id":"T401","span":{"begin":61,"end":69},"obj":"NN"},{"id":"T402","span":{"begin":70,"end":72},"obj":"VBZ"},{"id":"T403","span":{"begin":73,"end":82},"obj":"JJ"},{"id":"T404","span":{"begin":83,"end":86},"obj":"IN"},{"id":"T405","span":{"begin":87,"end":93},"obj":"JJ"},{"id":"T406","span":{"begin":94,"end":105},"obj":"NN"},{"id":"T407","span":{"begin":106,"end":108},"obj":"IN"},{"id":"T408","span":{"begin":109,"end":113},"obj":"RBR"},{"id":"T409","span":{"begin":114,"end":120},"obj":"JJ"},{"id":"T410","span":{"begin":121,"end":124},"obj":"CC"},{"id":"T411","span":{"begin":125,"end":134},"obj":"JJ"},{"id":"T412","span":{"begin":135,"end":139},"obj":"NNS"},{"id":"T413","span":{"begin":141,"end":148},"obj":"RB"},{"id":"T414","span":{"begin":148,"end":149},"obj":"-COMMA-"},{"id":"T415","span":{"begin":150,"end":161},"obj":"NN"},{"id":"T416","span":{"begin":162,"end":164},"obj":"IN"},{"id":"T417","span":{"begin":165,"end":168},"obj":"DT"},{"id":"T418","span":{"begin":169,"end":172},"obj":"NN"},{"id":"T419","span":{"begin":173,"end":175},"obj":"NN"},{"id":"T420","span":{"begin":176,"end":179},"obj":"CC"},{"id":"T421","span":{"begin":180,"end":183},"obj":"PRP-DOLLAR-"},{"id":"T422","span":{"begin":184,"end":190},"obj":"NN"},{"id":"T423","span":{"begin":191,"end":194},"obj":"VBZ"},{"id":"T424","span":{"begin":195,"end":201},"obj":"VBN"},{"id":"T425","span":{"begin":202,"end":203},"obj":"DT"},{"id":"T426","span":{"begin":204,"end":210},"obj":"JJ"},{"id":"T427","span":{"begin":211,"end":214},"obj":"CC"},{"id":"T428","span":{"begin":215,"end":224},"obj":"JJ"},{"id":"T429","span":{"begin":225,"end":233},"obj":"NN"},{"id":"T430","span":{"begin":234,"end":237},"obj":"IN"},{"id":"T431","span":{"begin":238,"end":248},"obj":"VBG"},{"id":"T432","span":{"begin":249,"end":252},"obj":"DT"},{"id":"T433","span":{"begin":253,"end":261},"obj":"JJ"},{"id":"T434","span":{"begin":262,"end":275},"obj":"NN"},{"id":"T435","span":{"begin":275,"end":276},"obj":"-COMMA-"},{"id":"T436","span":{"begin":277,"end":287},"obj":"JJ"},{"id":"T437","span":{"begin":288,"end":299},"obj":"NN"},{"id":"T438","span":{"begin":300,"end":303},"obj":"CC"},{"id":"T439","span":{"begin":304,"end":310},"obj":"NN"},{"id":"T440","span":{"begin":311,"end":313},"obj":"IN"},{"id":"T441","span":{"begin":314,"end":325},"obj":"JJ"},{"id":"T442","span":{"begin":326,"end":330},"obj":"NNS"},{"id":"T443","span":{"begin":331,"end":334},"obj":"CC"},{"id":"T444","span":{"begin":335,"end":337},"obj":"VBZ"},{"id":"T445","span":{"begin":338,"end":340},"obj":"DT"},{"id":"T446","span":{"begin":341,"end":349},"obj":"VBG"},{"id":"T447","span":{"begin":350,"end":357},"obj":"NN"},{"id":"T448","span":{"begin":358,"end":360},"obj":"TO"},{"id":"T449","span":{"begin":361,"end":364},"obj":"DT"},{"id":"T450","span":{"begin":365,"end":376},"obj":"NN"},{"id":"T451","span":{"begin":377,"end":379},"obj":"IN"},{"id":"T452","span":{"begin":380,"end":383},"obj":"DT"},{"id":"T453","span":{"begin":384,"end":394},"obj":"NN"},{"id":"T454","span":{"begin":395,"end":407},"obj":"NNS"}],"relations":[{"id":"R402","pred":"arg1Of","subj":"T394","obj":"T393"},{"id":"R403","pred":"arg1Of","subj":"T394","obj":"T395"},{"id":"R404","pred":"arg2Of","subj":"T396","obj":"T395"},{"id":"R405","pred":"arg1Of","subj":"T399","obj":"T396"},{"id":"R406","pred":"arg1Of","subj":"T398","obj":"T397"},{"id":"R407","pred":"arg1Of","subj":"T398","obj":"T399"},{"id":"R408","pred":"arg2Of","subj":"T401","obj":"T399"},{"id":"R409","pred":"arg1Of","subj":"T401","obj":"T400"},{"id":"R410","pred":"arg1Of","subj":"T394","obj":"T402"},{"id":"R411","pred":"arg2Of","subj":"T403","obj":"T402"},{"id":"R412","pred":"arg1Of","subj":"T394","obj":"T403"},{"id":"R413","pred":"arg1Of","subj":"T403","obj":"T404"},{"id":"R414","pred":"arg2Of","subj":"T406","obj":"T404"},{"id":"R415","pred":"arg1Of","subj":"T406","obj":"T405"},{"id":"R416","pred":"arg1Of","subj":"T406","obj":"T407"},{"id":"R417","pred":"arg2Of","subj":"T412","obj":"T407"},{"id":"R418","pred":"arg1Of","subj":"T412","obj":"T408"},{"id":"R419","pred":"arg1Of","subj":"T412","obj":"T409"},{"id":"R420","pred":"arg1Of","subj":"T409","obj":"T410"},{"id":"R421","pred":"arg2Of","subj":"T411","obj":"T410"},{"id":"R422","pred":"arg1Of","subj":"T412","obj":"T411"},{"id":"R423","pred":"arg1Of","subj":"T443","obj":"T413"},{"id":"R424","pred":"arg1Of","subj":"T443","obj":"T414"},{"id":"R425","pred":"arg1Of","subj":"T415","obj":"T416"},{"id":"R426","pred":"arg2Of","subj":"T420","obj":"T416"},{"id":"R427","pred":"arg1Of","subj":"T4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understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sample-Pubtator
{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1220","span":{"begin":56,"end":60},"obj":"Gene"},{"id":"1221","span":{"begin":184,"end":190},"obj":"Chemical"}],"attributes":[{"id":"A1220","pred":"pubann:denotes","subj":"1220","obj":"Gene:2213"},{"id":"A1221","pred":"pubann:denotes","subj":"1221","obj":"MESH:D011134"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sample-sentences
{"project":"LitCovid-sample-sentences","denotations":[{"id":"T332","span":{"begin":0,"end":140},"obj":"Sentence"},{"id":"T333","span":{"begin":141,"end":408},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sample-PD-FMA
{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T453","span":{"begin":29,"end":37},"obj":"Body_part"},{"id":"T454","span":{"begin":169,"end":172},"obj":"Body_part"}],"attributes":[{"id":"A453","pred":"fma_id","subj":"T453","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A454","pred":"fma_id","subj":"T454","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T332","span":{"begin":0,"end":140},"obj":"Sentence"},{"id":"T333","span":{"begin":141,"end":408},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Further understanding of how antibody structure affects FcγR function is essential for future development of more potent and effective mAbs. Already, engineering of the IgG Fc and its glycan has proved a potent and effective approach for increasing the clinical effectiveness, functional specificity and safety of therapeutic mAbs and is an emerging pathway to the development of the “next‐gen” therapeutics."}