PMC:7228307 / 24052-24379
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 426 | 274-278 | Gene | denotes | FcγR | Gene:2213 |
| 427 | 165-169 | Gene | denotes | FcγR | Gene:2213 |
| 428 | 115-119 | Chemical | denotes | ADCP | |
| 429 | 98-110 | Disease | denotes | cytotoxicity | MESH:D064420 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T247 | 171-176 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T40 | 115-119 | Disease | denotes | ADCP | http://purl.obolibrary.org/obo/MONDO_0022697 |
| T41 | 303-306 | Disease | denotes | MOA | http://purl.obolibrary.org/obo/MONDO_0016702 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T464 | 165-167 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T465 | 171-176 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T466 | 208-216 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T467 | 274-276 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T141 | 171-176 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
| T142 | 279-287 | http://purl.obolibrary.org/obo/BFO_0000034 | denotes | function |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 426 | 274-278 | Gene | denotes | FcγR | Gene:2213 |
| 427 | 165-169 | Gene | denotes | FcγR | Gene:2213 |
| 428 | 115-119 | Chemical | denotes | ADCP | |
| 429 | 98-110 | Disease | denotes | cytotoxicity | MESH:D064420 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T139 | 0-195 | Sentence | denotes | Although the action of agonistic/antagonistic mAbs is mechanistically distinct to those eliciting cytotoxicity and ADCP, the distance segregation between target and FcγR+ cells is also important. |
| T140 | 196-327 | Sentence | denotes | Indeed, the membrane proximal epitopes of CD28 and CD40 are important for the FcγR function in the complex MOA of these mAbs.43, 44 |
LitCovid-sample-UniProt
| Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
|---|---|---|---|---|---|
| T250 | 238-242 | Protein | denotes | CD28 | https://www.uniprot.org/uniprot/Q9BYV0|https://www.uniprot.org/uniprot/Q8WXJ2|https://www.uniprot.org/uniprot/Q8NI56|https://www.uniprot.org/uniprot/Q8NI55|https://www.uniprot.org/uniprot/Q8NI54|https://www.uniprot.org/uniprot/Q70WG0|https://www.uniprot.org/uniprot/Q6GSH7|https://www.uniprot.org/uniprot/Q52M23|https://www.uniprot.org/uniprot/Q28071|https://www.uniprot.org/uniprot/Q13964|https://www.uniprot.org/uniprot/P42069|https://www.uniprot.org/uniprot/P31042|https://www.uniprot.org/uniprot/P31041|https://www.uniprot.org/uniprot/P10747|https://www.uniprot.org/uniprot/O02757|https://www.uniprot.org/uniprot/A8KAC1 |
| T266 | 247-251 | Protein | denotes | CD40 | https://www.uniprot.org/uniprot/Q9BYU0|https://www.uniprot.org/uniprot/Q99NE3|https://www.uniprot.org/uniprot/Q99NE2|https://www.uniprot.org/uniprot/Q99NE1|https://www.uniprot.org/uniprot/Q99NE0|https://www.uniprot.org/uniprot/Q8SQ34|https://www.uniprot.org/uniprot/Q8K2X6|https://www.uniprot.org/uniprot/Q86YK5|https://www.uniprot.org/uniprot/Q7YRL5|https://www.uniprot.org/uniprot/Q7M4Q8|https://www.uniprot.org/uniprot/Q5U007|https://www.uniprot.org/uniprot/Q5JY15|https://www.uniprot.org/uniprot/Q542B1|https://www.uniprot.org/uniprot/Q53GN5|https://www.uniprot.org/uniprot/Q3ZTK5|https://www.uniprot.org/uniprot/Q3UBH3|https://www.uniprot.org/uniprot/Q3U7C9|https://www.uniprot.org/uniprot/Q3U799|https://www.uniprot.org/uniprot/Q3TSL2|https://www.uniprot.org/uniprot/Q3TS33|https://www.uniprot.org/uniprot/Q3LRP1|https://www.uniprot.org/uniprot/Q28203|https://www.uniprot.org/uniprot/P27512|https://www.uniprot.org/uniprot/P25942|https://www.uniprot.org/uniprot/E1P5S9|https://www.uniprot.org/uniprot/A7YWS9 |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T246 | 171-176 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-sample-PD-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 217-225 | http://purl.obolibrary.org/obo/MAT_0000491 | denotes | proximal |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T139 | 0-195 | Sentence | denotes | Although the action of agonistic/antagonistic mAbs is mechanistically distinct to those eliciting cytotoxicity and ADCP, the distance segregation between target and FcγR+ cells is also important. |
| T140 | 196-327 | Sentence | denotes | Indeed, the membrane proximal epitopes of CD28 and CD40 are important for the FcγR function in the complex MOA of these mAbs.43, 44 |