PMC:7228307 / 224-637 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7228307","sourcedb":"PMC","sourceid":"7228307","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7228307","text":"ith antigen‐complexed immunoglobulin (Ig)G ligands to both activate and modulate a powerful network of inflammatory host‐protective effector functions that are key to the normal physiology of immune resistance to pathogens. More than 100 therapeutic monoclonal antibodies (mAbs) are approved or in late stage clinical trials, many of which harness the potent FcγR‐mediated effector systems to varying degrees. Thi","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"21","span":{"begin":359,"end":363},"obj":"Gene"}],"attributes":[{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"Gene:2213"},{"subj":"21","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2","span":{"begin":22,"end":36},"obj":"Body_part"},{"id":"T3","span":{"begin":37,"end":42},"obj":"Body_part"},{"id":"T4","span":{"begin":38,"end":40},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma62871"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T7","span":{"begin":59,"end":67},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T8","span":{"begin":81,"end":82},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T9","span":{"begin":359,"end":361},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":4,"end":11},"obj":"Chemical"},{"id":"T2","span":{"begin":43,"end":50},"obj":"Chemical"},{"id":"T3","span":{"begin":132,"end":140},"obj":"Chemical"},{"id":"T4","span":{"begin":373,"end":381},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T1","span":{"begin":22,"end":36},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T2","span":{"begin":38,"end":40},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A1","pred":"meddra_id","subj":"T1","obj":"http://purl.bioontology.org/ontology/MEDDRA/10021496"},{"id":"A2","pred":"meddra_id","subj":"T2","obj":"http://purl.bioontology.org/ontology/MEDDRA/10021496"},{"subj":"T1","pred":"source","obj":"LitCovid-sample-MedDRA"},{"subj":"T2","pred":"source","obj":"LitCovid-sample-MedDRA"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T2","span":{"begin":116,"end":120},"obj":"http://purl.obolibrary.org/obo/IDO_0000531"},{"id":"T3","span":{"begin":141,"end":150},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T4","span":{"begin":213,"end":222},"obj":"http://purl.obolibrary.org/obo/IDO_0000528"}],"attributes":[{"subj":"T2","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T3","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T4","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"21","span":{"begin":359,"end":363},"obj":"Gene"}],"attributes":[{"id":"A21","pred":"pubann:denotes","subj":"21","obj":"Gene:2213"},{"subj":"21","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T7","span":{"begin":224,"end":409},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T2","span":{"begin":22,"end":36},"obj":"Body_part"},{"id":"T3","span":{"begin":37,"end":42},"obj":"Body_part"},{"id":"T4","span":{"begin":38,"end":40},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma62871"},{"subj":"T2","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T3","pred":"source","obj":"LitCovid-sample-PD-FMA"},{"subj":"T4","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":224,"end":409},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#e893ec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#93ecce"},{"id":"LitCovid-PD-CLO","color":"#ecb493"},{"id":"LitCovid-PD-CHEBI","color":"#9a93ec"},{"id":"LitCovid-sample-MedDRA","color":"#a5ec93"},{"id":"LitCovid-sample-PD-IDO","color":"#ec93bf"},{"id":"LitCovid-sample-Pubtator","color":"#93d9ec"},{"id":"LitCovid-sample-sentences","color":"#ece493"},{"id":"LitCovid-sample-PD-FMA","color":"#ca93ec"},{"id":"LitCovid-sentences","color":"#93ecb0"}]}]}}