PMC:7228307 / 11263-12161 JSON TXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

{"project":"LitCovid-PubTator","denotations":[{"id":"213","span":{"begin":55,"end":60},"obj":"Gene"},{"id":"214","span":{"begin":74,"end":78},"obj":"Gene"},{"id":"215","span":{"begin":97,"end":109},"obj":"Gene"},{"id":"216","span":{"begin":212,"end":216},"obj":"Gene"},{"id":"217","span":{"begin":361,"end":365},"obj":"Gene"},{"id":"218","span":{"begin":382,"end":390},"obj":"Gene"},{"id":"219","span":{"begin":403,"end":407},"obj":"Gene"},{"id":"220","span":{"begin":597,"end":601},"obj":"Gene"},{"id":"221","span":{"begin":615,"end":622},"obj":"Gene"},{"id":"222","span":{"begin":635,"end":639},"obj":"Gene"},{"id":"223","span":{"begin":799,"end":807},"obj":"Gene"},{"id":"224","span":{"begin":274,"end":280},"obj":"Species"},{"id":"225","span":{"begin":576,"end":584},"obj":"Gene"},{"id":"226","span":{"begin":192,"end":199},"obj":"Gene"},{"id":"227","span":{"begin":556,"end":559},"obj":"Chemical"},{"id":"228","span":{"begin":473,"end":490},"obj":"Disease"},{"id":"229","span":{"begin":740,"end":757},"obj":"Disease"}],"attributes":[{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"Gene:2214"},{"id":"A214","pred":"tao:has_database_id","subj":"214","obj":"Gene:3502"},{"id":"A215","pred":"tao:has_database_id","subj":"215","obj":"Gene:3458"},{"id":"A216","pred":"tao:has_database_id","subj":"216","obj":"Gene:3502"},{"id":"A217","pred":"tao:has_database_id","subj":"217","obj":"Gene:3502"},{"id":"A218","pred":"tao:has_database_id","subj":"218","obj":"Gene:2214"},{"id":"A219","pred":"tao:has_database_id","subj":"219","obj":"Gene:3502"},{"id":"A220","pred":"tao:has_database_id","subj":"220","obj":"Gene:3502"},{"id":"A221","pred":"tao:has_database_id","subj":"221","obj":"Gene:2213"},{"id":"A222","pred":"tao:has_database_id","subj":"222","obj":"Gene:3502"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Gene:2215"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Tax:9606"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"Gene:2215"},{"id":"A226","pred":"tao:has_database_id","subj":"226","obj":"Gene:2212"},{"id":"A227","pred":"tao:has_database_id","subj":"227","obj":"MESH:D010649"},{"id":"A228","pred":"tao:has_database_id","subj":"228","obj":"MESH:D007635"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"MESH:D007635"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":863,"end":871},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0001987"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-PD-CLO

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T194","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T195","span":{"begin":55,"end":57},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T196","span":{"begin":113,"end":122},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T197","span":{"begin":150,"end":164},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T198","span":{"begin":186,"end":191},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T199","span":{"begin":192,"end":194},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T200","span":{"begin":250,"end":252},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T201","span":{"begin":325,"end":326},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T202","span":{"begin":339,"end":341},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T203","span":{"begin":347,"end":348},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T204","span":{"begin":373,"end":381},"obj":"http://purl.obolibrary.org/obo/CL_0000623"},{"id":"T205","span":{"begin":382,"end":384},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T206","span":{"begin":410,"end":418},"obj":"http://purl.obolibrary.org/obo/CL_0000623"},{"id":"T207","span":{"begin":462,"end":471},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T208","span":{"begin":473,"end":496},"obj":"http://purl.obolibrary.org/obo/CL_0000782"},{"id":"T209","span":{"begin":576,"end":578},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T210","span":{"begin":615,"end":617},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T211","span":{"begin":647,"end":648},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T212","span":{"begin":667,"end":676},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T213","span":{"begin":740,"end":763},"obj":"http://purl.obolibrary.org/obo/CL_0000782"},{"id":"T214","span":{"begin":765,"end":773},"obj":"http://purl.obolibrary.org/obo/CL_0000623"},{"id":"T215","span":{"begin":799,"end":801},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T216","span":{"begin":808,"end":812},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T217","span":{"begin":835,"end":841},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T218","span":{"begin":849,"end":855},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T219","span":{"begin":849,"end":855},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T220","span":{"begin":849,"end":855},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T221","span":{"begin":849,"end":855},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T222","span":{"begin":863,"end":871},"obj":"http://purl.obolibrary.org/obo/UBERON_0001987"},{"id":"T223","span":{"begin":863,"end":871},"obj":"http://www.ebi.ac.uk/efo/EFO_0001407"},{"id":"T224","span":{"begin":884,"end":898},"obj":"http://purl.obolibrary.org/obo/CL_0000451"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-PD-CHEBI

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T53","span":{"begin":58,"end":60},"obj":"Chemical"},{"id":"T55","span":{"begin":97,"end":107},"obj":"Chemical"},{"id":"T56","span":{"begin":556,"end":559},"obj":"Chemical"}],"attributes":[{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_73814"},{"id":"A54","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_8753"},{"id":"A55","pred":"chebi_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A56","pred":"chebi_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/CHEBI_17295"},{"id":"A57","pred":"chebi_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/CHEBI_29997"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-PD-IDO

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T70","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T71","span":{"begin":160,"end":164},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T72","span":{"begin":186,"end":191},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T73","span":{"begin":287,"end":297},"obj":"http://purl.obolibrary.org/obo/CL_0000738"},{"id":"T74","span":{"begin":376,"end":381},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T75","span":{"begin":413,"end":418},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T76","span":{"begin":491,"end":496},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T77","span":{"begin":758,"end":763},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T78","span":{"begin":768,"end":773},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T79","span":{"begin":894,"end":898},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-CHEBI

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T7","span":{"begin":556,"end":559},"obj":"Chemical"}],"attributes":[{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17295"},{"id":"A8","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_29997"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-Pubtator

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"213","span":{"begin":55,"end":60},"obj":"Gene"},{"id":"214","span":{"begin":74,"end":78},"obj":"Gene"},{"id":"215","span":{"begin":97,"end":109},"obj":"Gene"},{"id":"216","span":{"begin":212,"end":216},"obj":"Gene"},{"id":"217","span":{"begin":361,"end":365},"obj":"Gene"},{"id":"218","span":{"begin":382,"end":390},"obj":"Gene"},{"id":"219","span":{"begin":403,"end":407},"obj":"Gene"},{"id":"220","span":{"begin":597,"end":601},"obj":"Gene"},{"id":"221","span":{"begin":615,"end":622},"obj":"Gene"},{"id":"222","span":{"begin":635,"end":639},"obj":"Gene"},{"id":"223","span":{"begin":799,"end":807},"obj":"Gene"},{"id":"224","span":{"begin":274,"end":280},"obj":"Species"},{"id":"225","span":{"begin":576,"end":584},"obj":"Gene"},{"id":"226","span":{"begin":192,"end":199},"obj":"Gene"},{"id":"227","span":{"begin":556,"end":559},"obj":"Chemical"},{"id":"228","span":{"begin":473,"end":490},"obj":"Disease"},{"id":"229","span":{"begin":740,"end":757},"obj":"Disease"}],"attributes":[{"id":"A222","pred":"pubann:denotes","subj":"222","obj":"Gene:3502"},{"id":"A224","pred":"pubann:denotes","subj":"224","obj":"Tax:9606"},{"id":"A219","pred":"pubann:denotes","subj":"219","obj":"Gene:3502"},{"id":"A220","pred":"pubann:denotes","subj":"220","obj":"Gene:3502"},{"id":"A227","pred":"pubann:denotes","subj":"227","obj":"MESH:D010649"},{"id":"A214","pred":"pubann:denotes","subj":"214","obj":"Gene:3502"},{"id":"A223","pred":"pubann:denotes","subj":"223","obj":"Gene:2215"},{"id":"A226","pred":"pubann:denotes","subj":"226","obj":"Gene:2212"},{"id":"A215","pred":"pubann:denotes","subj":"215","obj":"Gene:3458"},{"id":"A217","pred":"pubann:denotes","subj":"217","obj":"Gene:3502"},{"id":"A218","pred":"pubann:denotes","subj":"218","obj":"Gene:2214"},{"id":"A216","pred":"pubann:denotes","subj":"216","obj":"Gene:3502"},{"id":"A221","pred":"pubann:denotes","subj":"221","obj":"Gene:2213"},{"id":"A225","pred":"pubann:denotes","subj":"225","obj":"Gene:2215"},{"id":"A213","pred":"pubann:denotes","subj":"213","obj":"Gene:2214"},{"id":"A228","pred":"pubann:denotes","subj":"228","obj":"MESH:D007635"},{"id":"A229","pred":"pubann:denotes","subj":"229","obj":"MESH:D007635"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-sentences

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T61","span":{"begin":0,"end":54},"obj":"Sentence"},{"id":"T62","span":{"begin":55,"end":191},"obj":"Sentence"},{"id":"T63","span":{"begin":192,"end":338},"obj":"Sentence"},{"id":"T64","span":{"begin":339,"end":381},"obj":"Sentence"},{"id":"T65","span":{"begin":382,"end":408},"obj":"Sentence"},{"id":"T66","span":{"begin":410,"end":528},"obj":"Sentence"},{"id":"T67","span":{"begin":529,"end":575},"obj":"Sentence"},{"id":"T68","span":{"begin":576,"end":614},"obj":"Sentence"},{"id":"T69","span":{"begin":615,"end":722},"obj":"Sentence"},{"id":"T70","span":{"begin":723,"end":834},"obj":"Sentence"},{"id":"T71","span":{"begin":835,"end":898},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-PD-UBERON

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T3","span":{"begin":863,"end":871},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0001987"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-UniProt

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T76","span":{"begin":97,"end":107},"obj":"Protein"},{"id":"T78","span":{"begin":181,"end":185},"obj":"Protein"},{"id":"T81","span":{"begin":842,"end":848},"obj":"Protein"}],"attributes":[{"id":"A76","pred":"uniprot_id","subj":"T76","obj":"https://www.uniprot.org/uniprot/P51527"},{"id":"A77","pred":"uniprot_id","subj":"T76","obj":"https://www.uniprot.org/uniprot/P51526"},{"id":"A78","pred":"uniprot_id","subj":"T78","obj":"https://www.uniprot.org/uniprot/Q9NL57"},{"id":"A79","pred":"uniprot_id","subj":"T78","obj":"https://www.uniprot.org/uniprot/Q9NBD7"},{"id":"A80","pred":"uniprot_id","subj":"T78","obj":"https://www.uniprot.org/uniprot/A4V279"},{"id":"A81","pred":"uniprot_id","subj":"T81","obj":"https://www.uniprot.org/uniprot/Q9VPM8"},{"id":"A82","pred":"uniprot_id","subj":"T81","obj":"https://www.uniprot.org/uniprot/P91682"},{"id":"A83","pred":"uniprot_id","subj":"T81","obj":"https://www.uniprot.org/uniprot/B7FNK1"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-PD-FMA

LitCovid-sample-PD-MAT

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T1","span":{"begin":842,"end":855},"obj":"http://purl.obolibrary.org/obo/MAT_0000303"},{"id":"T2","span":{"begin":849,"end":855},"obj":"http://purl.obolibrary.org/obo/MAT_0000025"},{"id":"T3","span":{"begin":863,"end":871},"obj":"http://purl.obolibrary.org/obo/MAT_0000279"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T61","span":{"begin":0,"end":54},"obj":"Sentence"},{"id":"T62","span":{"begin":55,"end":191},"obj":"Sentence"},{"id":"T63","span":{"begin":192,"end":338},"obj":"Sentence"},{"id":"T64","span":{"begin":339,"end":381},"obj":"Sentence"},{"id":"T65","span":{"begin":382,"end":408},"obj":"Sentence"},{"id":"T66","span":{"begin":410,"end":528},"obj":"Sentence"},{"id":"T67","span":{"begin":529,"end":575},"obj":"Sentence"},{"id":"T68","span":{"begin":576,"end":614},"obj":"Sentence"},{"id":"T69","span":{"begin":615,"end":722},"obj":"Sentence"},{"id":"T70","span":{"begin":723,"end":834},"obj":"Sentence"},{"id":"T71","span":{"begin":835,"end":898},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

LitCovid-sample-Glycan

{"project":"LitCovid-sample-Glycan","denotations":[{"id":"T1","span":{"begin":283,"end":286},"obj":"https://glytoucan.org/Structures/Glycans/G05518TD"}],"text":"Receptor Affinity IgG specificity Cell distribution\nFcγRI High IgG1, IgG3, IgG4 Induced by interferon‐γ on monocytes, neutrophils, macrophages, dendritic cell subpopulations; mast cells\nFcγRIIa Low IgG1, IgG3, but IgG2 binding limited to the FcγRIIa‐H131 form, ~70% people) All leukocytes and platelets except T and B lymphocytes\nFcγRIIc a Low IgG1, IgG3, IgG4 NK cells\nFcγRIIIa Low IgG1, IgG3. NK cells, macrophages, subpopulation of circulating monocytes, myeloid dendritic cells, neutrophils at very low levels\nBinding avidity reduced by Phe at position 158\nFcγRIIIb Low IgG1, IgG3 Neutrophils\nFcγRIIb Low IgG1, IgG3, IgG4 B lymphocytes, some monocytes (can be upregulated); basophils; eosinophils? Plasmacytoid and myeloid dendritic cells; NK cells only of individuals with FcγRIIIb gene copy number variation\nAirway smooth muscle, LSEC, placenta, follicular dendritic cell"}

PMC:7228307 / 11263-12161 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7228307 / 11263-12161 JSON TXT