PMC:7219429 / 1189-1530 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T7","span":{"begin":48,"end":53},"obj":"Body_part"},{"id":"T8","span":{"begin":71,"end":76},"obj":"Body_part"},{"id":"T9","span":{"begin":82,"end":93},"obj":"Body_part"},{"id":"T10","span":{"begin":200,"end":211},"obj":"Body_part"},{"id":"T11","span":{"begin":247,"end":254},"obj":"Body_part"},{"id":"T12","span":{"begin":317,"end":327},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma82739"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T10","span":{"begin":230,"end":238},"obj":"Disease"}],"attributes":[{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T14","span":{"begin":69,"end":70},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T15","span":{"begin":104,"end":105},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T16","span":{"begin":147,"end":154},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T17","span":{"begin":305,"end":306},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T15","span":{"begin":36,"end":39},"obj":"Chemical"},{"id":"T16","span":{"begin":64,"end":67},"obj":"Chemical"},{"id":"T19","span":{"begin":71,"end":76},"obj":"Chemical"},{"id":"T20","span":{"begin":82,"end":93},"obj":"Chemical"},{"id":"T21","span":{"begin":122,"end":130},"obj":"Chemical"},{"id":"T22","span":{"begin":177,"end":180},"obj":"Chemical"},{"id":"T23","span":{"begin":200,"end":211},"obj":"Chemical"},{"id":"T24","span":{"begin":247,"end":254},"obj":"Chemical"},{"id":"T25","span":{"begin":284,"end":287},"obj":"Chemical"},{"id":"T26","span":{"begin":292,"end":295},"obj":"Chemical"},{"id":"T29","span":{"begin":317,"end":327},"obj":"Chemical"},{"id":"T30","span":{"begin":317,"end":322},"obj":"Chemical"},{"id":"T31","span":{"begin":323,"end":327},"obj":"Chemical"}],"attributes":[{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A17","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A18","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_23357"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A27","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A28","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":64,"end":67},"obj":"GlycoEpitope"},{"id":"T2","span":{"begin":292,"end":295},"obj":"GlycoEpitope"}],"attributes":[{"id":"A1","pred":"glyco_epitope_db_id","subj":"T1","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A2","pred":"glyco_epitope_db_id","subj":"T2","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-sentences","denotations":[{"id":"T15","span":{"begin":156,"end":255},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}

{"project":"LitCovid-PubTator","denotations":[{"id":"61","span":{"begin":241,"end":246},"obj":"Gene"},{"id":"66","span":{"begin":230,"end":240},"obj":"Species"},{"id":"74","span":{"begin":48,"end":53},"obj":"Chemical"},{"id":"75","span":{"begin":64,"end":67},"obj":"Chemical"},{"id":"76","span":{"begin":71,"end":76},"obj":"Chemical"},{"id":"77","span":{"begin":82,"end":93},"obj":"Chemical"},{"id":"78","span":{"begin":200,"end":211},"obj":"Chemical"}],"attributes":[{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"Gene:43740568"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Tax:2697049"},{"id":"A74","pred":"tao:has_database_id","subj":"74","obj":"MESH:D000073893"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"MESH:D005677"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"MESH:D008055"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"MESH:D005732"},{"id":"A78","pred":"tao:has_database_id","subj":"78","obj":"MESH:D005732"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"lecular similarity is shown between ATM and the sugar moiety of GM1, a lipid raft ganglioside acting as a host attachment cofactor for respiratory viruses. Due to this mimicry, ATM interacts with the ganglioside-binding domain of SARS-CoV-2 spike protein. This binding site shared by ATM and GM1 displays a conserved amino acid triad Q-134/F"}