PMC:7212965 / 21863-23250 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T36","span":{"begin":647,"end":651},"obj":"Body_part"},{"id":"T37","span":{"begin":667,"end":672},"obj":"Body_part"},{"id":"T38","span":{"begin":847,"end":853},"obj":"Body_part"}],"attributes":[{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma312401"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":647,"end":651},"obj":"Body_part"},{"id":"T28","span":{"begin":667,"end":672},"obj":"Body_part"},{"id":"T29","span":{"begin":847,"end":853},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0007311"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T86","span":{"begin":66,"end":74},"obj":"Disease"},{"id":"T87","span":{"begin":112,"end":120},"obj":"Disease"},{"id":"T88","span":{"begin":224,"end":232},"obj":"Disease"},{"id":"T89","span":{"begin":251,"end":278},"obj":"Disease"},{"id":"T90","span":{"begin":269,"end":278},"obj":"Disease"},{"id":"T91","span":{"begin":533,"end":541},"obj":"Disease"},{"id":"T92","span":{"begin":957,"end":965},"obj":"Disease"},{"id":"T93","span":{"begin":1016,"end":1024},"obj":"Disease"},{"id":"T94","span":{"begin":1133,"end":1141},"obj":"Disease"},{"id":"T95","span":{"begin":1378,"end":1386},"obj":"Disease"}],"attributes":[{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A89","pred":"mondo_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/MONDO_0024355"},{"id":"A90","pred":"mondo_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A91","pred":"mondo_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A92","pred":"mondo_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A93","pred":"mondo_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A94","pred":"mondo_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A95","pred":"mondo_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

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{"project":"LitCovid-PD-HP","denotations":[{"id":"T81","span":{"begin":66,"end":74},"obj":"Phenotype"},{"id":"T82","span":{"begin":112,"end":120},"obj":"Phenotype"},{"id":"T83","span":{"begin":224,"end":232},"obj":"Phenotype"},{"id":"T84","span":{"begin":257,"end":278},"obj":"Phenotype"},{"id":"T85","span":{"begin":471,"end":489},"obj":"Phenotype"},{"id":"T86","span":{"begin":533,"end":541},"obj":"Phenotype"},{"id":"T87","span":{"begin":567,"end":581},"obj":"Phenotype"},{"id":"T88","span":{"begin":647,"end":663},"obj":"Phenotype"},{"id":"T89","span":{"begin":835,"end":843},"obj":"Phenotype"},{"id":"T90","span":{"begin":935,"end":951},"obj":"Phenotype"},{"id":"T91","span":{"begin":957,"end":965},"obj":"Phenotype"},{"id":"T92","span":{"begin":1133,"end":1141},"obj":"Phenotype"},{"id":"T93","span":{"begin":1177,"end":1199},"obj":"Phenotype"},{"id":"T94","span":{"begin":1226,"end":1240},"obj":"Phenotype"}],"attributes":[{"id":"A81","pred":"hp_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A82","pred":"hp_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A83","pred":"hp_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A84","pred":"hp_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/HP_0011947"},{"id":"A85","pred":"hp_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/HP_0002017"},{"id":"A86","pred":"hp_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A87","pred":"hp_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/HP_0002027"},{"id":"A88","pred":"hp_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/HP_0002113"},{"id":"A89","pred":"hp_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A90","pred":"hp_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/HP_0002017"},{"id":"A91","pred":"hp_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A92","pred":"hp_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A93","pred":"hp_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/HP_0002017"},{"id":"A94","pred":"hp_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/HP_0002027"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

{"project":"2_test","denotations":[{"id":"32407808-32213556-43469281","span":{"begin":170,"end":172},"obj":"32213556"},{"id":"32407808-32213556-43469282","span":{"begin":719,"end":721},"obj":"32213556"},{"id":"32407808-32213556-43469283","span":{"begin":866,"end":868},"obj":"32213556"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

{"project":"LitCovid-sentences","denotations":[{"id":"T152","span":{"begin":0,"end":288},"obj":"Sentence"},{"id":"T153","span":{"begin":289,"end":423},"obj":"Sentence"},{"id":"T154","span":{"begin":424,"end":602},"obj":"Sentence"},{"id":"T155","span":{"begin":603,"end":693},"obj":"Sentence"},{"id":"T156","span":{"begin":694,"end":966},"obj":"Sentence"},{"id":"T157","span":{"begin":967,"end":1261},"obj":"Sentence"},{"id":"T158","span":{"begin":1262,"end":1387},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}

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the 43 studies that informed our analysis on the prevalence of diarrhea, we extracted information on whether diarrhea was reported as the only presenting symptom.50 , 60 In only 2 studies, there was explicit reporting of diarrhea in the absence of upper respiratory infection symptoms. In a study by Luo et al50 of 1141 patients, 183 patients (16%) presented with GI symptoms only in the absence of respiratory symptoms. Of 1141 patients, loss of appetite (15.8%) and nausea or vomiting (11.7%) were the most common symptoms, but diarrhea was reported in 6.0% and abdominal pain in 3.9% of patients. Notably, the majority of patients (96%) had lung infiltrates on chest computed tomography. In the study by Jin et al60 of 651 hospitalized patients, 21 patients (3.2%) presented with GI symptoms only (and no respiratory symptoms of coughing or sputum production).60 GI symptoms were defined as at least 1 of the following symptoms: nausea, vomiting, and diarrhea. Conversely, in the US study of 116 patients with COVID-19, Cholankeril et al70 reported that 31.9% of patients had GI symptoms on admission (median duration, 1 day); diarrhea was reported in 10.3% (12 of 116), nausea and/or vomiting in 10.3% (12 of 116), and abdominal pain in 8.8% (10 of 116). The authors explicitly reported that none of the 116 patients had isolated GI symptoms as the only manifestation of COVID-19."}