> top > docs > PMC:7212949 > spans > 22050-26537 > annotations

PMC:7212949 / 22050-26537 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T111 470-475 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T112 503-508 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T113 640-645 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T114 829-834 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T115 845-850 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T116 1228-1239 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T117 1271-1283 Body_part denotes Muscle fiber http://purl.org/sig/ont/fma/fma67328
T118 1757-1762 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T119 2420-2425 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T120 3182-3187 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T121 3269-3274 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T122 3748-3756 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T123 3913-3918 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T124 4002-4007 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T125 4022-4027 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T126 4050-4055 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T127 4130-4135 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T128 4190-4200 Body_part denotes hemoglobin http://purl.org/sig/ont/fma/fma62293
T129 4387-4406 Body_part denotes right bundle branch http://purl.org/sig/ont/fma/fma9486
T130 4476-4486 Body_part denotes troponin-I http://purl.org/sig/ont/fma/fma62340

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T63 470-475 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T64 503-508 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T65 640-645 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T66 829-834 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T67 845-850 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T68 1217-1224 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T69 1757-1762 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T70 2420-2425 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T71 3182-3187 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T72 3269-3274 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T73 3913-3918 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T74 4002-4007 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T75 4022-4027 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T76 4050-4055 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T77 4130-4135 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T163 41-49 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T164 64-72 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T165 74-78 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T166 523-526 Disease denotes CHF http://purl.obolibrary.org/obo/MONDO_0005009
T167 565-568 Disease denotes CHF http://purl.obolibrary.org/obo/MONDO_0005009
T168 584-605 Disease denotes Sudden cardiac arrest http://purl.obolibrary.org/obo/MONDO_0007264
T169 591-605 Disease denotes cardiac arrest http://purl.obolibrary.org/obo/MONDO_0000745
T170 614-616 Disease denotes MI http://purl.obolibrary.org/obo/MONDO_0005068
T171 621-631 Disease denotes arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T172 829-842 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T173 988-990 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T174 1072-1074 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T175 1078-1080 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T176 1383-1391 Disease denotes Diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T177 1522-1526 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T178 1626-1632 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T179 1790-1792 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T180 1807-1815 Disease denotes myositis http://purl.obolibrary.org/obo/MONDO_0008054|http://purl.obolibrary.org/obo/MONDO_0021167
T182 1957-1967 Disease denotes arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T183 2185-2188 Disease denotes CHF http://purl.obolibrary.org/obo/MONDO_0005009
T184 2201-2213 Disease denotes Pericarditis http://purl.obolibrary.org/obo/MONDO_0005904
T185 2328-2339 Disease denotes Myocarditis http://purl.obolibrary.org/obo/MONDO_0004496
T186 2398-2419 Disease denotes myocarditis and acute http://purl.obolibrary.org/obo/MONDO_0002815
T187 2398-2409 Disease denotes myocarditis http://purl.obolibrary.org/obo/MONDO_0004496
T188 2420-2433 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T189 2566-2574 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T190 2885-2891 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T191 2969-2972 Disease denotes HTN http://purl.obolibrary.org/obo/MONDO_0005044
T192 3078-3084 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T193 3122-3132 Disease denotes Arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T194 3269-3282 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T195 3406-3408 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T196 3625-3637 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T197 3647-3658 Disease denotes arrhythmias http://purl.obolibrary.org/obo/MONDO_0007263
T198 3674-3680 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T199 3723-3729 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T200 3822-3841 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T201 4034-4037 Disease denotes CHF http://purl.obolibrary.org/obo/MONDO_0005009
T202 4039-4063 Disease denotes congestive heart failure http://purl.obolibrary.org/obo/MONDO_0005009
T203 4050-4063 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T204 4065-4067 Disease denotes CK http://purl.obolibrary.org/obo/MONDO_0017941
T205 4298-4323 Disease denotes MI, myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T206 4387-4412 Disease denotes right bundle branch block http://purl.obolibrary.org/obo/MONDO_0001662
T207 4393-4412 Disease denotes bundle branch block http://purl.obolibrary.org/obo/MONDO_0007240
T208 4414-4418 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T209 4424-4457 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T189 199-201 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T190 199-201 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T191 255-258 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes Pan
T192 470-475 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T193 503-508 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T194 640-645 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T195 829-834 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T196 829-834 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T197 829-834 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T198 829-834 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T199 845-850 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T200 953-955 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T201 965-967 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T202 1002-1004 http://purl.obolibrary.org/obo/CLO_0003622 denotes Hb
T203 1066-1067 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T204 1162-1163 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T205 1166-1167 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T206 1170-1171 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T207 1217-1224 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessels
T208 1271-1277 http://purl.obolibrary.org/obo/UBERON_0001630 denotes Muscle
T209 1271-1277 http://purl.obolibrary.org/obo/UBERON_0005090 denotes Muscle
T210 1271-1277 http://www.ebi.ac.uk/efo/EFO_0000801 denotes Muscle
T211 1271-1277 http://www.ebi.ac.uk/efo/EFO_0001949 denotes Muscle
T212 1292-1293 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T213 1757-1762 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T214 1757-1762 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T215 1757-1762 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T216 1757-1762 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T217 1768-1773 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T218 1864-1866 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T219 2119-2123 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T220 2342-2343 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T221 2346-2347 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T222 2420-2425 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T223 2420-2425 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T224 2420-2425 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T225 2420-2425 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T226 2456-2457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T227 3182-3187 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T228 3205-3207 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T229 3230-3232 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T230 3269-3274 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T231 3269-3274 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T232 3269-3274 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T233 3269-3274 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T234 3409-3411 http://purl.obolibrary.org/obo/PR_000010213 denotes MB
T235 3414-3415 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T236 3440-3442 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T237 3440-3442 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T238 3913-3918 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T239 3913-3918 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T240 3913-3918 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T241 3913-3918 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T242 3970-3971 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T243 3989-3996 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T244 4002-4007 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T245 4002-4007 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T246 4022-4027 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T247 4022-4027 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T248 4022-4027 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T249 4022-4027 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T250 4050-4055 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T251 4050-4055 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T252 4050-4055 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T253 4050-4055 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T254 4130-4135 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T255 4164-4172 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T256 4186-4188 http://purl.obolibrary.org/obo/CLO_0003622 denotes Hb

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T53 199-201 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T54 614-616 Chemical denotes MI http://purl.obolibrary.org/obo/CHEBI_53620|http://purl.obolibrary.org/obo/CHEBI_74704
T56 690-692 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T57 921-923 Chemical denotes Ca http://purl.obolibrary.org/obo/CHEBI_22984
T58 947-949 Chemical denotes Mg http://purl.obolibrary.org/obo/CHEBI_25107
T59 2257-2260 Chemical denotes BNP http://purl.obolibrary.org/obo/CHEBI_80234
T60 2265-2275 Chemical denotes Creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T61 2298-2300 Chemical denotes LV http://purl.obolibrary.org/obo/CHEBI_73579
T62 2866-2868 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T63 3440-3442 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T64 3536-3538 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T65 3965-3968 Chemical denotes BNP http://purl.obolibrary.org/obo/CHEBI_80234
T66 3989-3996 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T67 3998-4000 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T68 4069-4077 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T70 4092-4100 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T72 4190-4200 Chemical denotes hemoglobin http://purl.obolibrary.org/obo/CHEBI_35143
T73 4233-4240 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T74 4298-4300 Chemical denotes MI http://purl.obolibrary.org/obo/CHEBI_53620|http://purl.obolibrary.org/obo/CHEBI_74704

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T21 1102-1106 http://purl.obolibrary.org/obo/GO_0004111 denotes CKMB
T22 1284-1289 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T23 3406-3411 http://purl.obolibrary.org/obo/GO_0004111 denotes CK-MB
T24 4086-4090 http://purl.obolibrary.org/obo/GO_0004111 denotes CKMB

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T137 470-480 Phenotype denotes Chest pain http://purl.obolibrary.org/obo/HP_0100749
T138 503-513 Phenotype denotes chest pain http://purl.obolibrary.org/obo/HP_0100749
T139 523-526 Phenotype denotes CHF http://purl.obolibrary.org/obo/HP_0001635
T140 565-568 Phenotype denotes CHF http://purl.obolibrary.org/obo/HP_0001635
T141 584-605 Phenotype denotes Sudden cardiac arrest http://purl.obolibrary.org/obo/HP_0031628
T142 621-631 Phenotype denotes arrhythmia http://purl.obolibrary.org/obo/HP_0011675
T143 640-650 Phenotype denotes Chest pain http://purl.obolibrary.org/obo/HP_0100749
T144 795-807 Phenotype denotes cardiomegaly http://purl.obolibrary.org/obo/HP_0001640
T145 829-842 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T146 869-881 Phenotype denotes Palpitations http://purl.obolibrary.org/obo/HP_0001962
T147 1193-1198 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T148 1561-1570 Phenotype denotes Hypoxemia http://purl.obolibrary.org/obo/HP_0012418
T149 1807-1815 Phenotype denotes myositis http://purl.obolibrary.org/obo/HP_0100614
T150 1909-1920 Phenotype denotes Tachycardia http://purl.obolibrary.org/obo/HP_0001649
T151 1949-1967 Phenotype denotes Cardiac arrhythmia http://purl.obolibrary.org/obo/HP_0011675
T152 2185-2188 Phenotype denotes CHF http://purl.obolibrary.org/obo/HP_0001635
T153 2201-2213 Phenotype denotes Pericarditis http://purl.obolibrary.org/obo/HP_0001701
T154 2328-2339 Phenotype denotes Myocarditis http://purl.obolibrary.org/obo/HP_0012819
T155 2398-2409 Phenotype denotes myocarditis http://purl.obolibrary.org/obo/HP_0012819
T156 2420-2433 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T157 3122-3132 Phenotype denotes Arrhythmia http://purl.obolibrary.org/obo/HP_0011675
T158 3167-3179 Phenotype denotes Palpitations http://purl.obolibrary.org/obo/HP_0001962
T159 3182-3197 Phenotype denotes Chest tightness http://purl.obolibrary.org/obo/HP_0031352
T160 3269-3282 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T161 3285-3302 Phenotype denotes Cardiogenic Shock http://purl.obolibrary.org/obo/HP_0030149
T162 3440-3461 Phenotype denotes ST segment elevations http://purl.obolibrary.org/obo/HP_0012251
T163 3625-3637 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T164 3647-3658 Phenotype denotes arrhythmias http://purl.obolibrary.org/obo/HP_0011675
T165 3748-3762 Phenotype denotes Cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T166 3765-3774 Phenotype denotes Hypoxemia http://purl.obolibrary.org/obo/HP_0012418
T167 3822-3841 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T168 4034-4037 Phenotype denotes CHF http://purl.obolibrary.org/obo/HP_0001635
T169 4039-4063 Phenotype denotes congestive heart failure http://purl.obolibrary.org/obo/HP_0001635
T170 4302-4323 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T171 4387-4412 Phenotype denotes right bundle branch block http://purl.obolibrary.org/obo/HP_0011712

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T224 0-73 Sentence denotes Table 2 Cardiovascular manifestations of SARS-CoV, MERS-CoV and COVID-19.
T225 74-130 Sentence denotes SARS (only studies with large study population included)
T226 131-449 Sentence denotes Study Booth et al (2003)N = 144, confirmed casesRetrospective study Li et al (2003)N = 46, confirmed casesProspective study Pan et al (2003)N = 15, confirmed casesRetrospective study Ding et al (2004)N = 8 (4 confirmed cases, 4 control)Clinicopathologic study Yu et al (2006)N = 121, confirmed casesRetrospective study
T227 450-686 Sentence denotes Clinical features • Chest pain (10%)• ↑HR (46%) • No chest pain or overt CHF on admission• ↓HR (non-ICU) ↑HR (ICU)•CHF exacerbation • Sudden cardiac arrest (100%)• MI and arrhythmia (33%) • Chest pain • ↑HR (71.9%) (62.8%, 45.4%, 35.5%)
T228 687-781 Sentence denotes • ↓BP (50.4%) (28.1%, 21.5%, 14.8% during the first, second, third week)↓HR, transient (14.9%)
T229 782-842 Sentence denotes • Reversible cardiomegaly (10.7%), no clinical heart failure
T230 843-866 Sentence denotes • Chest discomfort (7%)
T231 867-886 Sentence denotes • Palpitations (4%)
T232 887-931 Sentence denotes Key findings on investigations • ↓Ca++ (60%)
T233 932-943 Sentence denotes • ↓K+ (26%)
T234 944-957 Sentence denotes • ↓Mg++ (18%)
T235 958-969 Sentence denotes • ↓P+ (27%)
T236 970-990 Sentence denotes • ↑ LDH (87%) • ↑ CK
T237 991-998 Sentence denotes • ↑ LDH
T238 999-1004 Sentence denotes • ↓Hb
T239 1005-1016 Sentence denotes • EKG: RBBB
T240 1017-1074 Sentence denotes • Echo: ↓LVEF • Abnormal cardiac enzymes (66%) N/A • ↑ CK
T241 1075-1106 Sentence denotes • ↑CK (26%) without TnI or CKMB
T242 1107-1114 Sentence denotes • ↑ LDH
T243 1115-1139 Sentence denotes • CXR or CT abnormality:
T244 1140-1144 Sentence denotes 100%
T245 1145-1198 Sentence denotes Histopathology N/A N/A N/A • Myocardial stromal edema
T246 1199-1239 Sentence denotes • Infiltration of vessels by lymphocytes
T247 1240-1268 Sentence denotes • Focal hyaline degeneration
T248 1269-1293 Sentence denotes • Muscle fiber lysis N/A
T249 1294-1344 Sentence denotes Key study findings and message • 20% ICU admission
T250 1345-1380 Sentence denotes • 6.5% Case fatality rate (21 days)
T251 1381-1599 Sentence denotes • Diabetes and other comorbidities independently associated with poor prognosis Possibly reversible subclinical diastolic impairment seen in SARS patients Proposed causes of SCD:• Hypoxemia leading to myocardial strain
T252 1600-1632 Sentence denotes • Direct viral myocardial injury
T253 1633-1673 Sentence denotes • Stress aggravates pre-existing disease
T254 1674-1841 Sentence denotes • Sympathetic response causing electrical myocardial instability ACE2 expressed in heart, but virus not detected • ↑CK likely due to myositis as cardiac enzymes normal
T255 1842-1861 Sentence denotes • 15% ICU admission
T256 1862-1906 Sentence denotes • 18 (5) days mean duration of hospital stay
T257 1907-1946 Sentence denotes • Tachycardia persists during follow up
T258 1947-1979 Sentence denotes • Cardiac arrhythmia is uncommon
T259 1980-1984 Sentence denotes MERS
T260 1985-2166 Sentence denotes Study Alhogbani (2016)N = 1 confirmed caseCase report Almekhlafi et al (2016)N = 31, confirmed casesRetrospective study Garout et al (2018)N = 52, confirmed casesRetrospective study
T261 2167-2213 Sentence denotes Clinical features CHF ↑HR (67.7%) Pericarditis
T262 2214-2252 Sentence denotes Key findings on investigations • ↑ TnI
T263 2253-2260 Sentence denotes • ↑ BNP
T264 2261-2275 Sentence denotes • ↑ Creatinine
T265 2276-2283 Sentence denotes • Echo:
T266 2284-2312 Sentence denotes Severe global LV dysfunction
T267 2313-2327 Sentence denotes • Cardiac MRI:
T268 2328-2347 Sentence denotes Myocarditis N/A N/A
T269 2348-2490 Sentence denotes Key study findings and message MERS-CoV may cause myocarditis and acute heart failure • Vasopressor need is a risk factor for death (P = 0.04)
T270 2491-2565 Sentence denotes • 80.6% vasopressor support rate No association of ECMO need with outcomes
T271 2566-2574 Sentence denotes COVID-19
T272 2575-2844 Sentence denotes Study Huang et al (2020)N = 41, confirmed casesRetrospective study Wang et al (2020)N = 138, confirmed casesRetrospective study Zheng et al (2020)Review Bhatraju et al (2020)N = 24, confirmed casesRetrospective study Fried et al (2020)N = 4, confirmed casesCase reports
T273 2845-2868 Sentence denotes Clinical features • ↑BP
T274 2869-3008 Sentence denotes • Acute cardiac injury (12%) more in ICU patients than non-ICU patients (31% vs. 4%) • Pre-existing HTN (31.2%) (58.3% in ICU, significant)
T275 3009-3061 Sentence denotes • Pre-existing CVD (14.5%) (25% in ICU, significant)
T276 3062-3119 Sentence denotes • Acute cardiac injury (7.2%) (22.2% in ICU, significant)
T277 3120-3179 Sentence denotes • Arrhythmia (16.7%) (44.4% in ICU patients) • Palpitations
T278 3180-3209 Sentence denotes • Chest tightness • ↑HR (48%)
T279 3210-3252 Sentence denotes • Vasopressor need (71%) • Myopericarditis
T280 3253-3282 Sentence denotes • Decompensated heart failure
T281 3283-3302 Sentence denotes • Cardiogenic Shock
T282 3303-3401 Sentence denotes Key findings on investigations • ↑ TnI (12%) (31% in ICU patients, 4% in non-ICU patients) • ↑ TnI
T283 3402-3461 Sentence denotes • ↑ CK-MB N/A • ↑ TnI (15%) • Diffuse ST segment elevations
T284 3462-3488 Sentence denotes • Elevated cardiac enzymes
T285 3489-3503 Sentence denotes • LVEF on echo
T286 3504-3745 Sentence denotes Key Study findings and message ↑BP more common in ICU patients (P = 0.018) ICU patients more likely to have pre-existing hypertension, develop arrhythmias, acute cardiac injury (P < 0.001) Proposed mechanism of cardiac injury:• ACE 2 related
T287 3746-3762 Sentence denotes • Cytokine storm
T288 3763-3874 Sentence denotes • Hypoxemia • ICU admission most commonly due to hypoxemic respiratory failure, vasopressor requirement or both
T289 3875-3964 Sentence denotes • 50% mortality • Similar symptoms in heart transplant patients as nontransplant patients
T290 3965-4487 Sentence denotes BNP, B-type natriuretic peptide; BP, blood pressure; HR, heart rate; CHF, congestive heart failure; CK, creatine kinase; CKMB, creatine kinase myocardial band; CXR; chest x-ray; ECMO, extracorporeal membrane oxygenation; Hb, hemoglobin; ICU, intensive care unit; LDH, lactate dehydrogenase; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MERS-CoV, middle east respiratory syndrome coronavirus; RBBB, right bundle branch block; SARS-COV, severe acute respiratory syndrome coronavirus; TnI, troponin-I.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1722 41-49 SP_10 denotes SARS-CoV
T1723 51-59 SP_9 denotes MERS-CoV
T1724 64-72 SP_7 denotes COVID-19
T1726 314-317 CHEBI:85129;DG_29;CHEBI:85129 denotes Din
T1727 388-399 GO:0007567 denotes dy Yu et al
T1729 546-553 GO:0007565 denotes non-ICU
T1730 617-620 UBERON:0002113 denotes and
T1732 882-909 GO:0007565 denotes (4%) Key findings on invest
T1733 1121-1154 GO:0007567 denotes or CT abnormality: 100% Histopath
T1735 1353-1365 GO:0042571;GO:0016064 denotes ase fatality
T1736 1366-1370 GO:0016064 denotes rate
T1737 1470-1488 GO:0007565 denotes reversible subclin
T1738 1626-1652 GO:0016265 denotes injury • Stress aggravates
T1740 1807-1841 UBERON:0001987 denotes myositis as cardiac enzymes normal
T1742 2176-2187 GO:0016265 denotes features CH
T1743 2384-2387 SP_7 denotes CoV
T1744 2474-2479 GO:0016265 denotes death
T1745 2724-2756 UBERON:0000995 denotes iew Bhatraju et al (2020)N = 24,
T1747 3406-3413 PR:000001786 denotes CK-MB N
T1748 3639-3658 GO:0016265 denotes develop arrhythmias
T1749 3791-3795 GO:0007565 denotes most
T1750 3839-3890 UBERON:0001004 denotes re, vasopressor requirement or both • 50% mortality
T1751 3913-3929 GO:0007567 denotes heart transplant
T1754 4207-4221 UBERON:0007221 denotes intensive care
T1756 4279-4312 GO:0007565 denotes ejection fraction; MI, myocardial
T1757 4325-4333 SP_9 denotes MERS-CoV
T1758 4335-4346 SP_9 denotes middle east
T1759 4347-4358 SP_9;GO:0045333;UBERON:0001004 denotes respiratory
T1760 4359-4379 SP_9 denotes syndrome coronavirus
T1761 4414-4422 SP_10 denotes SARS-COV
T1762 4424-4436 SP_10 denotes severe acute
T1763 4437-4448 SP_10;UBERON:0001004 denotes respiratory
T1764 4449-4469 SP_10 denotes syndrome coronavirus
T807 66-71 UBERON:0002113 denotes VID-1
T808 168-176 SP_10 denotes irmed ca
T809 178-186 SP_9 denotes sRetrosp
T810 191-199 SP_7 denotes e study
T811 206-211 SP_10 denotes l (20
T812 1098-1100 UBERON:0005409 denotes o
T813 1295-1303 UBERON:0004908 denotes ey study
T814 1535-1537 CHEBI:29103;CHEBI:29103 denotes P
T815 1553-1558 UBERON:0001988 denotes f SCD
T816 1597-1599 CHEBI:29103;CHEBI:29103 denotes in
T817 1614-1619 UBERON:0001988 denotes myoc
T818 1630-1635 NCBITaxon:10239 denotes ry •
T819 1651-1656 UBERON:0001988 denotes s pre
T820 1705-1707 CHEBI:29103;CHEBI:29103 denotes el
T821 1812-1817 NCBITaxon:10239 denotes tis a
T822 1840-1849 UBERON:0000483;CL:0000066 denotes l • 15% I
T823 1850-1855 CL:0000066 denotes U adm
T824 1859-1864 UBERON:0000160 denotes on •
T825 1891-1902 GO:0005902 denotes f hospital
T826 1911-1916 NCBITaxon:10239;GO:0006260 denotes chyca
T827 1917-1928 GO:0006260 denotes dia persist
T828 1932-1942 UBERON:0000160 denotes ring follo
T829 1959-1964 NCBITaxon:10239 denotes rhyth
T830 1981-1997 UBERON:0002108 denotes ERS Study Alhogb
T831 2098-2111 UBERON:0001199 denotes study Garout
T832 2160-2163 UBERON:0005409 denotes st
T833 2164-2179 UBERON:0001744 denotes dy Clinical fea
T834 2197-2205 SP_10 denotes 7%) Peri
T835 2228-2237 UBERON:0000483;CL:0000066 denotes n investi
T836 2238-2243 CL:0000066 denotes ation
T837 2444-2446 UBERON:0005409 denotes so
T838 2585-2590 CHEBI:27026;CHEBI:27026 denotes g et
T839 2607-2612 NCBITaxon:10239;GO:0006260 denotes confi
T840 2613-2624 GO:0006260 denotes med casesRe
T841 2718-2732 UBERON:0001728 denotes 20)Review Bhat
T842 2805-2810 NCBITaxon:10239 denotes 2020)
T843 2814-2824 CHEBI:33282;CHEBI:33282 denotes 4, confirm
T844 2867-2872 UBERON:0002405 denotes P • A
T845 2893-2904 CL:0000542 denotes 12%) more i
T846 3049-3051 UBERON:0005409 denotes si
T847 3403-3408 SP_6;NCBITaxon:9606 denotes ↑ CK
T848 3409-3419 UBERON:0000160;CL:0002563 denotes MB N/A • ↑
T849 3420-3429 CL:0002563;UBERON:0000483 denotes TnI (15%)
T850 3430-3434 CL:0002563 denotes • Di
T851 3461-3484 NCBITaxon:10088 denotes • Elevated cardiac enz
T852 3611-3621 UBERON:0000916 denotes pre-exist
T853 3845-3850 UBERON:0001988 denotes sopre
T854 3859-3864 NCBITaxon:10239 denotes ireme
T855 3873-3877 PR:000022138 denotes h •
T856 3887-3892 UBERON:0001988 denotes ity •
T857 4030-4035 UBERON:0001988 denotes te; C
T858 4067-4089 UBERON:0001558 denotes , creatine kinase; CKM
T859 4217-4227 UBERON:0000160;CL:0002563 denotes care unit;
T860 4228-4237 CL:0002563;UBERON:0000483 denotes LDH, lact
T861 4238-4243 CL:0002563 denotes te de
T862 4258-4263 NCBITaxon:10239;GO:0006260 denotes EF, l
T863 4264-4275 GO:0006260 denotes ft ventricu
T864 4314-4324 UBERON:0001004 denotes nfarction;
T865 4413-4418 NCBITaxon:10239 denotes SARS
T866 4438-4456 SP_7 denotes espiratory syndrom

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
588 3732-3737 Gene denotes ACE 2 Gene:59272
589 2910-2918 Species denotes patients Tax:9606
590 2932-2940 Species denotes patients Tax:9606
591 3155-3163 Species denotes patients Tax:9606
592 3360-3368 Species denotes patients Tax:9606
593 3384-3392 Species denotes patients Tax:9606
594 3558-3566 Species denotes patients Tax:9606
595 3583-3591 Species denotes patients Tax:9606
596 3930-3938 Species denotes patients Tax:9606
597 3956-3964 Species denotes patients Tax:9606
598 2566-2574 Disease denotes COVID-19 MESH:C000657245
599 2877-2891 Disease denotes cardiac injury MESH:D006331
600 3024-3027 Disease denotes CVD MESH:D002318
601 3070-3084 Disease denotes cardiac injury MESH:D006331
602 3122-3132 Disease denotes Arrhythmia MESH:D001145
603 3188-3203 Disease denotes tightness • ↑HR MESH:C536920
604 3237-3302 Disease denotes Myopericarditis • Decompensated heart failure • Cardiogenic Shock MESH:D012769
605 3625-3637 Disease denotes hypertension MESH:D006973
606 3647-3658 Disease denotes arrhythmias MESH:D001145
607 3666-3680 Disease denotes cardiac injury MESH:D006331
608 3715-3729 Disease denotes cardiac injury MESH:D006331
609 3757-3774 Disease denotes storm • Hypoxemia
610 3822-3841 Disease denotes respiratory failure MESH:D012131
611 3881-3890 Disease denotes mortality MESH:D003643
615 41-49 Species denotes SARS-CoV Tax:694009
616 51-59 Species denotes MERS-CoV Tax:1335626
617 64-72 Disease denotes COVID-19 MESH:C000657245
628 3965-3968 Gene denotes BNP Gene:4879
629 4065-4067 Gene denotes CK Gene:51727
630 4325-4333 Species denotes MERS-CoV Tax:1335626
631 4335-4379 Species denotes middle east respiratory syndrome coronavirus Tax:1335626
632 4414-4422 Species denotes SARS-COV Tax:694009
633 4424-4469 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
634 4034-4037 Disease denotes CHF
635 4039-4063 Disease denotes congestive heart failure MESH:D006333
636 4302-4323 Disease denotes myocardial infarction MESH:D009203
637 4387-4412 Disease denotes right bundle branch block MESH:D002037