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PMC:7205724 / 7094-7826 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
256 7-16 Species denotes SARS-CoV2 Tax:2697049
257 111-116 Species denotes human Tax:9606
266 180-184 Gene denotes ACE2 Gene:59272
267 260-264 Gene denotes ACE2 Gene:59272
268 139-147 Species denotes SARS-CoV Tax:694009
269 174-179 Species denotes human Tax:9606
270 192-202 Species denotes SARS-CoV 2 Tax:2697049
271 254-259 Species denotes human Tax:9606
272 468-476 Species denotes SARS-CoV Tax:694009
273 718-728 Species denotes SARS-CoV 2 Tax:2697049

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T54 54-65 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T48 7-11 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T49 139-147 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 192-200 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 468-476 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 718-726 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T81 111-116 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T82 174-179 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T83 213-214 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 254-259 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T85 368-371 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T104 54-65 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T105 54-59 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T106 60-65 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T73 54-65 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T63 7-16 Species denotes SARS-CoV2 NCBItxid:2697049
T64 111-116 Species denotes human NCBItxid:9606
T65 139-147 Species denotes SARS-CoV NCBItxid:694009
T66 174-179 Species denotes human NCBItxid:9606
T67 192-202 Species denotes SARS-CoV 2 NCBItxid:2697049
T68 254-259 Species denotes human NCBItxid:9606
T69 468-476 Species denotes SARS-CoV NCBItxid:694009
T70 718-728 Species denotes SARS-CoV 2 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T65 0-121 Sentence denotes 3.1.3 SARS-CoV2 receptor binding domain contains six amino acids providing favorable positions for binding to human ACE2
T66 122-347 Sentence denotes When compared to SARS-CoV SB, the motif binding the human ACE2 to the SARS-CoV 2 SB showed a relatively higher binding affinity for human ACE2 as indicated in smaller equilibrium dissociation constant (2.9 nM vs. 7.7 nM) [3].
T67 348-732 Sentence denotes Structural analysis has demonstrated that fourteen positions critically take part in the receptor-binding domain of the SARS-CoV SB that contain eight conserved (T402, Y436, Y440, N473, Y475, T486, G488, and Y491) positions and six semi-conserved (R426 to N448, Y442 to L464, L472 to F495, N479 to Q502, Y484 to Q507, and T487 to N510) substitutions with respect to the SARS-CoV 2 SB.

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
256 7-16 Species denotes SARS-CoV2 Tax:2697049
257 111-116 Species denotes human Tax:9606
268 139-147 Species denotes SARS-CoV Tax:694009
269 174-179 Species denotes human Tax:9606
266 180-184 Gene denotes ACE2 Gene:59272
270 192-202 Species denotes SARS-CoV 2 Tax:2697049
271 254-259 Species denotes human Tax:9606
267 260-264 Gene denotes ACE2 Gene:59272
272 468-476 Species denotes SARS-CoV Tax:694009
273 718-728 Species denotes SARS-CoV 2 Tax:2697049

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T1182 0-5 CD denotes 3.1.3
T1183 7-16 NN denotes SARS-CoV2
T1184 17-25 NN denotes receptor
T1185 26-33 NN denotes binding
T1186 34-40 NN denotes domain
T1187 41-49 VBZ denotes contains
T1188 50-53 CD denotes six
T1189 54-59 NN denotes amino
T1190 60-65 NNS denotes acids
T1191 66-75 VBG denotes providing
T1192 76-85 JJ denotes favorable
T1193 86-95 NNS denotes positions
T1194 96-99 IN denotes for
T1195 100-107 VBG denotes binding
T1196 108-110 TO denotes to
T1197 111-116 JJ denotes human
T1198 117-121 NN denotes ACE2
T1199 122-126 WRB denotes When
T1200 127-135 VBN denotes compared
T1201 136-138 TO denotes to
T1202 139-147 NNP denotes SARS-CoV
T1203 148-150 NNP denotes SB
T1204 150-151 -COMMA- denotes ,
T1205 152-155 DT denotes the
T1206 156-161 NN denotes motif
T1207 162-169 VBG denotes binding
T1208 170-173 DT denotes the
T1209 174-179 JJ denotes human
T1210 180-184 NN denotes ACE2
T1211 185-187 TO denotes to
T1212 188-191 DT denotes the
T1213 192-200 JJ denotes SARS-CoV
T1214 201-202 CD denotes 2
T1215 203-205 NN denotes SB
T1216 206-212 VBD denotes showed
T1217 213-214 DT denotes a
T1218 215-225 RB denotes relatively
T1219 226-232 JJR denotes higher
T1220 233-240 NN denotes binding
T1221 241-249 NN denotes affinity
T1222 250-253 IN denotes for
T1223 254-259 JJ denotes human
T1224 260-264 NN denotes ACE2
T1225 265-267 IN denotes as
T1226 268-277 VBN denotes indicated
T1227 278-280 IN denotes in
T1228 281-288 JJR denotes smaller
T1229 289-300 NN denotes equilibrium
T1230 301-313 NN denotes dissociation
T1231 314-322 NN denotes constant
T1232 323-324 -LRB- denotes (
T1233 324-330 NN denotes 2.9 nM
T1234 331-334 IN denotes vs.
T1235 335-341 NN denotes 7.7 nM
T1236 341-342 -RRB- denotes )
T1237 343-344 -LRB- denotes [
T1238 344-345 CD denotes 3
T1239 345-346 -RRB- denotes ]
T1240 348-358 JJ denotes Structural
T1241 359-367 NN denotes analysis
T1242 368-371 VBZ denotes has
T1243 372-384 VBN denotes demonstrated
T1244 385-389 IN denotes that
T1245 390-398 CD denotes fourteen
T1246 399-408 NNS denotes positions
T1247 409-419 RB denotes critically
T1248 420-424 VBP denotes take
T1249 425-429 NN denotes part
T1250 430-432 IN denotes in
T1251 433-436 DT denotes the
T1252 437-453 JJ denotes receptor-binding
T1253 454-460 NN denotes domain
T1254 461-463 IN denotes of
T1255 464-467 DT denotes the
T1256 468-476 NN denotes SARS-CoV
T1257 477-479 NN denotes SB
T1258 480-484 WDT denotes that
T1259 485-492 VBP denotes contain
T1260 493-498 CD denotes eight
T1261 499-508 VBN denotes conserved
T1262 509-510 -LRB- denotes (
T1263 510-514 NN denotes T402
T1264 514-515 -COMMA- denotes ,
T1265 516-520 NN denotes Y436
T1266 520-521 -COMMA- denotes ,
T1267 522-526 NN denotes Y440
T1268 526-527 -COMMA- denotes ,
T1269 528-532 NN denotes N473
T1270 532-533 -COMMA- denotes ,
T1271 534-538 NN denotes Y475
T1272 538-539 -COMMA- denotes ,
T1273 540-544 NN denotes T486
T1274 544-545 -COMMA- denotes ,
T1275 546-550 NN denotes G488
T1276 550-551 -COMMA- denotes ,
T1277 552-555 CC denotes and
T1278 556-560 NN denotes Y491
T1279 560-561 -RRB- denotes )
T1280 562-571 NNS denotes positions
T1281 572-575 CC denotes and
T1282 576-579 CD denotes six
T1283 580-594 JJ denotes semi-conserved
T1284 595-596 -LRB- denotes (
T1285 596-600 NN denotes R426
T1286 601-603 TO denotes to
T1287 604-608 NN denotes N448
T1288 608-609 -COMMA- denotes ,
T1289 610-614 NN denotes Y442
T1290 615-617 TO denotes to
T1291 618-622 NN denotes L464
T1292 622-623 -COMMA- denotes ,
T1293 624-628 NN denotes L472
T1294 629-631 TO denotes to
T1295 632-636 NN denotes F495
T1296 636-637 -COMMA- denotes ,
T1297 638-642 NN denotes N479
T1298 643-645 TO denotes to
T1299 646-650 NN denotes Q502
T1300 650-651 -COMMA- denotes ,
T1301 652-656 NN denotes Y484
T1302 657-659 TO denotes to
T1303 660-664 NN denotes Q507
T1304 664-665 -COMMA- denotes ,
T1305 666-669 CC denotes and
T1306 670-674 NN denotes T487
T1307 675-677 TO denotes to
T1308 678-682 NN denotes N510
T1309 682-683 -RRB- denotes )
T1310 684-697 NNS denotes substitutions
T1311 698-702 IN denotes with
T1312 703-710 NN denotes respect
T1313 711-713 TO denotes to
T1314 714-717 DT denotes the
T1315 718-726 JJ denotes SARS-CoV
T1316 727-728 CD denotes 2
T1317 729-731 NN denotes SB
R1203 T1215 T1212 arg1Of SB,the
R1204 T1215 T1213 arg1Of SB,SARS-CoV
R1205 T1215 T1214 arg1Of SB,2
R1206 T1206 T1216 arg1Of motif,showed
R1293 T1301 T1300 arg2Of Y484,","
R1294 T1301 T1302 arg1Of Y484,to
R1295 T1303 T1302 arg2Of Q507,to
R1296 T1305 T1304 arg1Of and,","
R1174 T1186 T1182 arg1Of domain,3.1.3
R1175 T1186 T1183 arg1Of domain,SARS-CoV2
R1176 T1186 T1184 arg1Of domain,receptor
R1177 T1186 T1185 arg1Of domain,binding
R1178 T1186 T1187 arg1Of domain,contains
R1179 T1190 T1187 arg2Of acids,contains
R1180 T1190 T1188 arg1Of acids,six
R1181 T1190 T1189 arg1Of acids,amino
R1182 T1190 T1191 arg1Of acids,providing
R1183 T1193 T1191 arg2Of positions,providing
R1184 T1193 T1192 arg1Of positions,favorable
R1185 T1193 T1194 arg1Of positions,for
R1186 T1195 T1194 arg2Of binding,for
R1187 T1195 T1196 arg1Of binding,to
R1188 T1198 T1196 arg2Of ACE2,to
R1189 T1198 T1197 arg1Of ACE2,human
R1190 T1216 T1199 arg1Of showed,When
R1191 T1200 T1199 arg2Of compared,When
R1192 T1200 T1201 arg1Of compared,to
R1193 T1203 T1201 arg2Of SB,to
R1194 T1203 T1202 arg1Of SB,SARS-CoV
R1195 T1216 T1204 arg1Of showed,","
R1196 T1206 T1205 arg1Of motif,the
R1197 T1206 T1207 arg1Of motif,binding
R1198 T1210 T1207 arg2Of ACE2,binding
R1199 T1210 T1208 arg1Of ACE2,the
R1200 T1210 T1209 arg1Of ACE2,human
R1201 T1210 T1211 arg1Of ACE2,to
R1202 T1215 T1211 arg2Of SB,to
R1207 T1221 T1216 arg2Of affinity,showed
R1208 T1225 T1216 arg3Of as,showed
R1209 T1221 T1217 arg1Of affinity,a
R1210 T1219 T1218 arg1Of higher,relatively
R1211 T1221 T1219 arg1Of affinity,higher
R1212 T1221 T1220 arg1Of affinity,binding
R1213 T1221 T1222 arg1Of affinity,for
R1214 T1224 T1222 arg2Of ACE2,for
R1215 T1224 T1223 arg1Of ACE2,human
R1216 T1226 T1225 arg2Of indicated,as
R1217 T1226 T1227 arg1Of indicated,in
R1218 T1231 T1227 arg2Of constant,in
R1219 T1231 T1228 arg1Of constant,smaller
R1220 T1231 T1229 arg1Of constant,equilibrium
R1221 T1231 T1230 arg1Of constant,dissociation
R1222 T1231 T1232 arg1Of constant,(
R1223 T1233 T1232 arg2Of 2.9 nM,(
R1224 T1236 T1232 arg3Of ),(
R1225 T1233 T1234 arg1Of 2.9 nM,vs.
R1226 T1235 T1234 arg2Of 7.7 nM,vs.
R1227 T1216 T1237 arg1Of showed,[
R1228 T1238 T1237 arg2Of 3,[
R1229 T1239 T1237 arg3Of ],[
R1230 T1241 T1240 arg1Of analysis,Structural
R1231 T1241 T1242 arg1Of analysis,has
R1232 T1243 T1242 arg2Of demonstrated,has
R1233 T1241 T1243 arg1Of analysis,demonstrated
R1234 T1248 T1243 arg2Of take,demonstrated
R1235 T1248 T1244 arg1Of take,that
R1236 T1246 T1245 arg1Of positions,fourteen
R1237 T1248 T1247 arg1Of take,critically
R1238 T1246 T1248 arg1Of positions,take
R1239 T1249 T1248 arg2Of part,take
R1240 T1248 T1250 arg1Of take,in
R1241 T1253 T1250 arg2Of domain,in
R1242 T1253 T1251 arg1Of domain,the
R1243 T1253 T1252 arg1Of domain,receptor-binding
R1244 T1253 T1254 arg1Of domain,of
R1245 T1257 T1254 arg2Of SB,of
R1246 T1257 T1255 arg1Of SB,the
R1247 T1257 T1256 arg1Of SB,SARS-CoV
R1248 T1257 T1258 arg1Of SB,that
R1249 T1257 T1259 arg1Of SB,contain
R1250 T1281 T1259 arg2Of and,contain
R1251 T1281 T1260 arg1Of and,eight
R1252 T1281 T1261 arg1Of and,conserved
R1253 T1280 T1262 arg1Of positions,(
R1254 T1277 T1262 arg2Of and,(
R1255 T1279 T1262 arg3Of ),(
R1256 T1263 T1264 arg1Of T402,","
R1257 T1265 T1264 arg2Of Y436,","
R1258 T1264 T1266 arg1Of ",",","
R1259 T1267 T1266 arg2Of Y440,","
R1260 T1266 T1268 arg1Of ",",","
R1261 T1269 T1268 arg2Of N473,","
R1262 T1268 T1270 arg1Of ",",","
R1263 T1271 T1270 arg2Of Y475,","
R1264 T1270 T1272 arg1Of ",",","
R1265 T1273 T1272 arg2Of T486,","
R1266 T1272 T1274 arg1Of ",",","
R1267 T1275 T1274 arg2Of G488,","
R1268 T1277 T1276 arg1Of and,","
R1269 T1274 T1277 arg1Of ",",and
R1270 T1278 T1277 arg2Of Y491,and
R1271 T1280 T1281 arg1Of positions,and
R1272 T1310 T1281 arg2Of substitutions,and
R1273 T1283 T1282 arg1Of semi-conserved,six
R1274 T1310 T1283 arg1Of substitutions,semi-conserved
R1275 T1283 T1284 arg1Of semi-conserved,(
R1276 T1296 T1284 arg2Of ",",(
R1277 T1309 T1284 arg3Of ),(
R1278 T1285 T1286 arg1Of R426,to
R1279 T1287 T1286 arg2Of N448,to
R1280 T1287 T1288 arg1Of N448,","
R1281 T1289 T1288 arg2Of Y442,","
R1282 T1289 T1290 arg1Of Y442,to
R1283 T1291 T1290 arg2Of L464,to
R1284 T1287 T1292 arg1Of N448,","
R1285 T1293 T1292 arg2Of L472,","
R1286 T1293 T1294 arg1Of L472,to
R1287 T1295 T1294 arg2Of F495,to
R1288 T1285 T1296 arg1Of R426,","
R1289 T1305 T1296 arg2Of and,","
R1290 T1297 T1298 arg1Of N479,to
R1291 T1299 T1298 arg2Of Q502,to
R1292 T1299 T1300 arg1Of Q502,","
R1297 T1297 T1305 arg1Of N479,and
R1298 T1306 T1305 arg2Of T487,and
R1299 T1305 T1307 arg1Of and,to
R1300 T1308 T1307 arg2Of N510,to
R1301 T1259 T1311 arg1Of contain,with
R1302 T1312 T1311 arg2Of respect,with
R1303 T1317 T1311 arg3Of SB,with
R1304 T1311 T1313 arg1Of with,to
R1305 T1317 T1314 arg1Of SB,the
R1306 T1317 T1315 arg1Of SB,SARS-CoV
R1307 T1317 T1316 arg1Of SB,2

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T54 54-65 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T47 7-16 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T48 139-147 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T49 192-202 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096
T50 468-476 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 718-728 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T65 0-121 Sentence denotes 3.1.3 SARS-CoV2 receptor binding domain contains six amino acids providing favorable positions for binding to human ACE2
T66 122-347 Sentence denotes When compared to SARS-CoV SB, the motif binding the human ACE2 to the SARS-CoV 2 SB showed a relatively higher binding affinity for human ACE2 as indicated in smaller equilibrium dissociation constant (2.9 nM vs. 7.7 nM) [3].
T67 348-732 Sentence denotes Structural analysis has demonstrated that fourteen positions critically take part in the receptor-binding domain of the SARS-CoV SB that contain eight conserved (T402, Y436, Y440, N473, Y475, T486, G488, and Y491) positions and six semi-conserved (R426 to N448, Y442 to L464, L472 to F495, N479 to Q502, Y484 to Q507, and T487 to N510) substitutions with respect to the SARS-CoV 2 SB.