PMC:7205724 / 607-1761
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
50 | 720-723 | Gene | denotes | IL6 | Gene:3569 |
51 | 903-906 | Gene | denotes | IL6 | Gene:3569 |
52 | 960-963 | Gene | denotes | IL6 | Gene:3569 |
53 | 4-21 | Species | denotes | novel coronavirus | Tax:2697049 |
54 | 23-32 | Species | denotes | SARS-CoV2 | Tax:2697049 |
55 | 86-92 | Species | denotes | humans | Tax:9606 |
56 | 177-185 | Species | denotes | patients | Tax:9606 |
57 | 243-252 | Species | denotes | SARS-CoV2 | Tax:2697049 |
58 | 284-292 | Species | denotes | patients | Tax:9606 |
59 | 389-396 | Species | denotes | patient | Tax:9606 |
60 | 836-844 | Species | denotes | patients | Tax:9606 |
61 | 941-949 | Species | denotes | patients | Tax:9606 |
62 | 1004-1013 | Species | denotes | SARS-CoV2 | Tax:2697049 |
63 | 1065-1074 | Species | denotes | SARS-CoV2 | Tax:2697049 |
64 | 860-871 | Chemical | denotes | Tocilizumab | MESH:C502936 |
65 | 58-71 | Disease | denotes | fatal disease | MESH:D034062 |
66 | 73-81 | Disease | denotes | COVID-19 | MESH:C000657245 |
67 | 155-163 | Disease | denotes | COVID-19 | MESH:C000657245 |
68 | 201-209 | Disease | denotes | COVID-19 | MESH:C000657245 |
69 | 305-313 | Disease | denotes | COVID-19 | MESH:C000657245 |
70 | 422-430 | Disease | denotes | COVID-19 | MESH:C000657245 |
71 | 454-466 | Disease | denotes | inflammation | MESH:D007249 |
72 | 544-552 | Disease | denotes | COVID-19 | MESH:C000657245 |
73 | 660-668 | Disease | denotes | COVID-19 | MESH:C000657245 |
74 | 677-682 | Disease | denotes | death | MESH:D003643 |
75 | 759-767 | Disease | denotes | COVID-19 | MESH:C000657245 |
76 | 850-858 | Disease | denotes | COVID-19 | MESH:C000657245 |
77 | 1137-1145 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T2 | 165-171 | Body_part | denotes | Plasma | http://purl.org/sig/ont/fma/fma62970 |
T3 | 711-719 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T4 | 747-755 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T5 | 886-894 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T6 | 1014-1018 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T7 | 1089-1102 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1089-1102 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T6 | 23-27 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 73-81 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T8 | 155-163 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T9 | 201-209 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T10 | 243-247 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T11 | 305-313 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T12 | 422-430 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 454-466 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T14 | 544-552 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T15 | 660-668 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T16 | 759-767 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 850-858 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T18 | 1004-1008 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T19 | 1065-1069 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T20 | 1137-1145 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 44-45 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 86-92 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
T3 | 165-171 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | Plasma |
T4 | 253-256 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T5 | 873-874 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T6 | 1014-1018 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T7 | 1089-1102 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T6 | 358-373 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
T7 | 497-512 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
T8 | 633-648 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
LitCovid-sample-MedDRA
Id | Subject | Object | Predicate | Lexical cue | meddra_id |
---|---|---|---|---|---|
T3 | 807-817 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | viral load | http://purl.bioontology.org/ontology/MEDDRA/10062178 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 64-71 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
T3 | 1014-1018 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T5 | 358-373 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
T6 | 497-512 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
T7 | 633-648 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T6 | 23-32 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T7 | 73-81 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T8 | 86-92 | Species | denotes | humans | NCBItxid:9605 |
T9 | 155-163 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T10 | 201-209 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T11 | 243-252 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T12 | 305-313 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T13 | 422-430 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T14 | 544-552 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T15 | 660-668 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T16 | 759-767 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T17 | 850-858 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T18 | 1004-1013 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T19 | 1065-1074 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T20 | 1137-1145 | Species | denotes | COVID-19 | NCBItxid:2697049 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-93 | Sentence | denotes | The novel coronavirus, SARS-CoV2, can cause a potentially fatal disease, COVID-19, in humans. |
T12 | 94-164 | Sentence | denotes | Here, we will provide an overview of therapeutic options for COVID-19. |
T13 | 165-314 | Sentence | denotes | Plasma from patients recovered from COVID-19 that contains antibodies against SARS-CoV2 has shown promising results in patients with severe COVID-19. |
T14 | 315-406 | Sentence | denotes | Also, IVIG, combined with moderate-dose of corticosteroids, might improve patient outcomes. |
T15 | 407-467 | Sentence | denotes | Evidence links COVID-19 to variable degrees of inflammation. |
T16 | 468-553 | Sentence | denotes | Studies show that the use of corticosteroids might accelerate recovery from COVID-19. |
T17 | 554-683 | Sentence | denotes | There are, however, no controlled clinical trials that show whether the use of corticosteroids can reduce COVID-19-related death. |
T18 | 684-859 | Sentence | denotes | Also, the pro-inflammatory cytokine IL6 is the best-documented cytokine in COVID-19 correlated with severity, criticality, viral load, and prognosis of patients with COVID-19. |
T19 | 860-971 | Sentence | denotes | Tocilizumab, a monoclonal antibody against IL6, could confer clinical benefit in patients with high IL6 levels. |
T20 | 972-1154 | Sentence | denotes | Essential elements that process SARS-CoV2 cell entry and specific characteristics that allow SARS-CoV2 to escape the immune system have the potential as targets for COVID-19 therapy. |
LitCovid-sample-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1089-1102 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
53 | 4-21 | Species | denotes | novel coronavirus | Tax:2697049 |
54 | 23-32 | Species | denotes | SARS-CoV2 | Tax:2697049 |
65 | 58-71 | Disease | denotes | fatal disease | MESH:D034062 |
66 | 73-81 | Disease | denotes | COVID-19 | MESH:C000657245 |
55 | 86-92 | Species | denotes | humans | Tax:9606 |
67 | 155-163 | Disease | denotes | COVID-19 | MESH:C000657245 |
56 | 177-185 | Species | denotes | patients | Tax:9606 |
68 | 201-209 | Disease | denotes | COVID-19 | MESH:C000657245 |
57 | 243-252 | Species | denotes | SARS-CoV2 | Tax:2697049 |
58 | 284-292 | Species | denotes | patients | Tax:9606 |
69 | 305-313 | Disease | denotes | COVID-19 | MESH:C000657245 |
59 | 389-396 | Species | denotes | patient | Tax:9606 |
70 | 422-430 | Disease | denotes | COVID-19 | MESH:C000657245 |
71 | 454-466 | Disease | denotes | inflammation | MESH:D007249 |
72 | 544-552 | Disease | denotes | COVID-19 | MESH:C000657245 |
73 | 660-668 | Disease | denotes | COVID-19 | MESH:C000657245 |
74 | 677-682 | Disease | denotes | death | MESH:D003643 |
50 | 720-723 | Gene | denotes | IL6 | Gene:3569 |
75 | 759-767 | Disease | denotes | COVID-19 | MESH:C000657245 |
60 | 836-844 | Species | denotes | patients | Tax:9606 |
76 | 850-858 | Disease | denotes | COVID-19 | MESH:C000657245 |
64 | 860-871 | Chemical | denotes | Tocilizumab | MESH:C502936 |
51 | 903-906 | Gene | denotes | IL6 | Gene:3569 |
61 | 941-949 | Species | denotes | patients | Tax:9606 |
52 | 960-963 | Gene | denotes | IL6 | Gene:3569 |
62 | 1004-1013 | Species | denotes | SARS-CoV2 | Tax:2697049 |
63 | 1065-1074 | Species | denotes | SARS-CoV2 | Tax:2697049 |
77 | 1137-1145 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T133 | 720-723 | Protein | denotes | IL6 | https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0 |
T177 | 903-906 | Protein | denotes | IL6 | https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0 |
T221 | 960-963 | Protein | denotes | IL6 | https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0 |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T92 | 0-3 | DT | denotes | The |
T93 | 4-9 | JJ | denotes | novel |
T94 | 10-21 | NN | denotes | coronavirus |
T95 | 21-22 | -COMMA- | denotes | , |
T96 | 23-32 | NN | denotes | SARS-CoV2 |
T97 | 32-33 | -COMMA- | denotes | , |
T98 | 34-37 | MD | denotes | can |
T99 | 38-43 | VB | denotes | cause |
T100 | 44-45 | DT | denotes | a |
T101 | 46-57 | RB | denotes | potentially |
T102 | 58-63 | JJ | denotes | fatal |
T103 | 64-71 | NN | denotes | disease |
T104 | 71-72 | -COMMA- | denotes | , |
T105 | 73-81 | NN | denotes | COVID-19 |
T106 | 81-82 | -COMMA- | denotes | , |
T107 | 83-85 | IN | denotes | in |
T108 | 86-92 | NNS | denotes | humans |
T109 | 94-98 | RB | denotes | Here |
T110 | 98-99 | -COMMA- | denotes | , |
T111 | 100-102 | PRP | denotes | we |
T112 | 103-107 | MD | denotes | will |
T113 | 108-115 | VB | denotes | provide |
T114 | 116-118 | DT | denotes | an |
T115 | 119-127 | NN | denotes | overview |
T116 | 128-130 | IN | denotes | of |
T117 | 131-142 | JJ | denotes | therapeutic |
T118 | 143-150 | NNS | denotes | options |
T119 | 151-154 | IN | denotes | for |
T120 | 155-163 | NN | denotes | COVID-19 |
T121 | 165-171 | NN | denotes | Plasma |
T122 | 172-176 | IN | denotes | from |
T123 | 177-185 | NNS | denotes | patients |
T124 | 186-195 | VBN | denotes | recovered |
T125 | 196-200 | IN | denotes | from |
T126 | 201-209 | NN | denotes | COVID-19 |
T127 | 210-214 | WDT | denotes | that |
T128 | 215-223 | VBZ | denotes | contains |
T129 | 224-234 | NNS | denotes | antibodies |
T130 | 235-242 | IN | denotes | against |
T131 | 243-252 | NN | denotes | SARS-CoV2 |
T132 | 253-256 | VBZ | denotes | has |
T133 | 257-262 | VBN | denotes | shown |
T134 | 263-272 | JJ | denotes | promising |
T135 | 273-280 | NNS | denotes | results |
T136 | 281-283 | IN | denotes | in |
T137 | 284-292 | NNS | denotes | patients |
T138 | 293-297 | IN | denotes | with |
T139 | 298-304 | JJ | denotes | severe |
T140 | 305-313 | NN | denotes | COVID-19 |
T141 | 315-319 | RB | denotes | Also |
T142 | 319-320 | -COMMA- | denotes | , |
T143 | 321-325 | NNP | denotes | IVIG |
T144 | 325-326 | -COMMA- | denotes | , |
T145 | 327-335 | VBN | denotes | combined |
T146 | 336-340 | IN | denotes | with |
T147 | 341-354 | NN | denotes | moderate-dose |
T148 | 355-357 | IN | denotes | of |
T149 | 358-373 | NNS | denotes | corticosteroids |
T150 | 373-374 | -COMMA- | denotes | , |
T151 | 375-380 | MD | denotes | might |
T152 | 381-388 | VB | denotes | improve |
T153 | 389-396 | NN | denotes | patient |
T154 | 397-405 | NNS | denotes | outcomes |
T155 | 407-415 | NN | denotes | Evidence |
T156 | 416-421 | VBZ | denotes | links |
T157 | 422-430 | NN | denotes | COVID-19 |
T158 | 431-433 | TO | denotes | to |
T159 | 434-442 | JJ | denotes | variable |
T160 | 443-450 | NNS | denotes | degrees |
T161 | 451-453 | IN | denotes | of |
T162 | 454-466 | NN | denotes | inflammation |
T163 | 468-475 | NNS | denotes | Studies |
T164 | 476-480 | VBP | denotes | show |
T165 | 481-485 | IN | denotes | that |
T166 | 486-489 | DT | denotes | the |
T167 | 490-493 | NN | denotes | use |
T168 | 494-496 | IN | denotes | of |
T169 | 497-512 | NNS | denotes | corticosteroids |
T170 | 513-518 | MD | denotes | might |
T171 | 519-529 | VB | denotes | accelerate |
T172 | 530-538 | NN | denotes | recovery |
T173 | 539-543 | IN | denotes | from |
T174 | 544-552 | NN | denotes | COVID-19 |
T175 | 554-559 | EX | denotes | There |
T176 | 560-563 | VBP | denotes | are |
T177 | 563-564 | -COMMA- | denotes | , |
T178 | 565-572 | RB | denotes | however |
T179 | 572-573 | -COMMA- | denotes | , |
T180 | 574-576 | DT | denotes | no |
T181 | 577-587 | JJ | denotes | controlled |
T182 | 588-596 | JJ | denotes | clinical |
T183 | 597-603 | NNS | denotes | trials |
T184 | 604-608 | WDT | denotes | that |
T185 | 609-613 | VBP | denotes | show |
T186 | 614-621 | IN | denotes | whether |
T187 | 622-625 | DT | denotes | the |
T188 | 626-629 | NN | denotes | use |
T189 | 630-632 | IN | denotes | of |
T190 | 633-648 | NNS | denotes | corticosteroids |
T191 | 649-652 | MD | denotes | can |
T192 | 653-659 | VB | denotes | reduce |
T193 | 660-676 | JJ | denotes | COVID-19-related |
T194 | 677-682 | NN | denotes | death |
T195 | 684-688 | RB | denotes | Also |
T196 | 688-689 | -COMMA- | denotes | , |
T197 | 690-693 | DT | denotes | the |
T198 | 694-710 | JJ | denotes | pro-inflammatory |
T199 | 711-719 | NN | denotes | cytokine |
T200 | 720-723 | NN | denotes | IL6 |
T201 | 724-726 | VBZ | denotes | is |
T202 | 727-730 | DT | denotes | the |
T203 | 731-746 | JJ | denotes | best-documented |
T204 | 747-755 | NN | denotes | cytokine |
T205 | 756-758 | IN | denotes | in |
T206 | 759-767 | NN | denotes | COVID-19 |
T207 | 768-778 | VBD | denotes | correlated |
T208 | 779-783 | IN | denotes | with |
T209 | 784-792 | NN | denotes | severity |
T210 | 792-793 | -COMMA- | denotes | , |
T211 | 794-805 | NN | denotes | criticality |
T212 | 805-806 | -COMMA- | denotes | , |
T213 | 807-812 | JJ | denotes | viral |
T214 | 813-817 | NN | denotes | load |
T215 | 817-818 | -COMMA- | denotes | , |
T216 | 819-822 | CC | denotes | and |
T217 | 823-832 | NN | denotes | prognosis |
T218 | 833-835 | IN | denotes | of |
T219 | 836-844 | NNS | denotes | patients |
T220 | 845-849 | IN | denotes | with |
T221 | 850-858 | NN | denotes | COVID-19 |
T222 | 860-871 | NNP | denotes | Tocilizumab |
T223 | 871-872 | -COMMA- | denotes | , |
T224 | 873-874 | DT | denotes | a |
T225 | 875-885 | JJ | denotes | monoclonal |
T226 | 886-894 | NN | denotes | antibody |
T227 | 895-902 | IN | denotes | against |
T228 | 903-906 | NN | denotes | IL6 |
T229 | 906-907 | -COMMA- | denotes | , |
T230 | 908-913 | MD | denotes | could |
T231 | 914-920 | VB | denotes | confer |
T232 | 921-929 | JJ | denotes | clinical |
T233 | 930-937 | NN | denotes | benefit |
T234 | 938-940 | IN | denotes | in |
T235 | 941-949 | NNS | denotes | patients |
T236 | 950-954 | IN | denotes | with |
T237 | 955-959 | JJ | denotes | high |
T238 | 960-963 | NN | denotes | IL6 |
T239 | 964-970 | NNS | denotes | levels |
T240 | 972-981 | JJ | denotes | Essential |
T241 | 982-990 | NNS | denotes | elements |
T242 | 991-995 | IN | denotes | that |
T243 | 996-1003 | NN | denotes | process |
T244 | 1004-1013 | NN | denotes | SARS-CoV2 |
T245 | 1014-1018 | NN | denotes | cell |
T246 | 1019-1024 | NN | denotes | entry |
T247 | 1025-1028 | CC | denotes | and |
T248 | 1029-1037 | JJ | denotes | specific |
T249 | 1038-1053 | NNS | denotes | characteristics |
T250 | 1054-1058 | WDT | denotes | that |
T251 | 1059-1064 | VBP | denotes | allow |
T252 | 1065-1074 | NN | denotes | SARS-CoV2 |
T253 | 1075-1077 | TO | denotes | to |
T254 | 1078-1084 | VB | denotes | escape |
T255 | 1085-1088 | DT | denotes | the |
T256 | 1089-1095 | JJ | denotes | immune |
T257 | 1096-1102 | NN | denotes | system |
T258 | 1103-1107 | VBP | denotes | have |
T259 | 1108-1111 | DT | denotes | the |
T260 | 1112-1121 | NN | denotes | potential |
T261 | 1122-1124 | IN | denotes | as |
T262 | 1125-1132 | NNS | denotes | targets |
T263 | 1133-1136 | IN | denotes | for |
T264 | 1137-1145 | NN | denotes | COVID-19 |
T265 | 1146-1153 | NN | denotes | therapy |
R245 | T254 | T253 | arg1Of | escape,to |
R246 | T252 | T254 | arg1Of | SARS-CoV2,escape |
R248 | T257 | T255 | arg1Of | system,the |
R249 | T257 | T256 | arg1Of | system,immune |
R250 | T247 | T258 | arg1Of | and,have |
R251 | T260 | T258 | arg2Of | potential,have |
R252 | T260 | T259 | arg1Of | potential,the |
R253 | T258 | T261 | arg1Of | have,as |
R85 | T94 | T92 | arg1Of | coronavirus,The |
R86 | T94 | T93 | arg1Of | coronavirus,novel |
R87 | T94 | T95 | arg1Of | coronavirus,"," |
R88 | T96 | T95 | arg2Of | SARS-CoV2,"," |
R89 | T99 | T97 | arg1Of | cause,"," |
R90 | T94 | T98 | arg1Of | coronavirus,can |
R91 | T99 | T98 | arg2Of | cause,can |
R92 | T94 | T99 | arg1Of | coronavirus,cause |
R93 | T103 | T99 | arg2Of | disease,cause |
R94 | T103 | T100 | arg1Of | disease,a |
R95 | T102 | T101 | arg1Of | fatal,potentially |
R96 | T103 | T102 | arg1Of | disease,fatal |
R97 | T103 | T104 | arg1Of | disease,"," |
R98 | T105 | T104 | arg2Of | COVID-19,"," |
R99 | T99 | T106 | arg1Of | cause,"," |
R100 | T99 | T107 | arg1Of | cause,in |
R101 | T108 | T107 | arg2Of | humans,in |
R102 | T113 | T109 | arg1Of | provide,Here |
R103 | T113 | T110 | arg1Of | provide,"," |
R104 | T111 | T112 | arg1Of | we,will |
R105 | T113 | T112 | arg2Of | provide,will |
R106 | T111 | T113 | arg1Of | we,provide |
R107 | T115 | T113 | arg2Of | overview,provide |
R108 | T115 | T114 | arg1Of | overview,an |
R109 | T115 | T116 | arg1Of | overview,of |
R110 | T118 | T116 | arg2Of | options,of |
R111 | T118 | T117 | arg1Of | options,therapeutic |
R112 | T115 | T119 | arg1Of | overview,for |
R113 | T120 | T119 | arg2Of | COVID-19,for |
R114 | T121 | T122 | arg1Of | Plasma,from |
R115 | T123 | T122 | arg2Of | patients,from |
R116 | T123 | T124 | arg2Of | patients,recovered |
R117 | T124 | T125 | arg1Of | recovered,from |
R118 | T126 | T125 | arg2Of | COVID-19,from |
R119 | T126 | T127 | arg1Of | COVID-19,that |
R120 | T126 | T128 | arg1Of | COVID-19,contains |
R121 | T129 | T128 | arg2Of | antibodies,contains |
R122 | T129 | T130 | arg1Of | antibodies,against |
R123 | T131 | T130 | arg2Of | SARS-CoV2,against |
R124 | T121 | T132 | arg1Of | Plasma,has |
R125 | T133 | T132 | arg2Of | shown,has |
R126 | T121 | T133 | arg1Of | Plasma,shown |
R127 | T135 | T133 | arg2Of | results,shown |
R128 | T135 | T134 | arg1Of | results,promising |
R129 | T133 | T136 | arg1Of | shown,in |
R130 | T137 | T136 | arg2Of | patients,in |
R131 | T137 | T138 | arg1Of | patients,with |
R132 | T140 | T138 | arg2Of | COVID-19,with |
R133 | T140 | T139 | arg1Of | COVID-19,severe |
R134 | T152 | T141 | arg1Of | improve,Also |
R135 | T152 | T142 | arg1Of | improve,"," |
R136 | T143 | T144 | arg1Of | IVIG,"," |
R137 | T143 | T145 | arg2Of | IVIG,combined |
R138 | T145 | T146 | arg1Of | combined,with |
R139 | T147 | T146 | arg2Of | moderate-dose,with |
R140 | T147 | T148 | arg1Of | moderate-dose,of |
R141 | T149 | T148 | arg2Of | corticosteroids,of |
R142 | T152 | T150 | arg1Of | improve,"," |
R143 | T143 | T151 | arg1Of | IVIG,might |
R144 | T152 | T151 | arg2Of | improve,might |
R145 | T143 | T152 | arg1Of | IVIG,improve |
R146 | T154 | T152 | arg2Of | outcomes,improve |
R147 | T154 | T153 | arg1Of | outcomes,patient |
R148 | T155 | T156 | arg1Of | Evidence,links |
R149 | T157 | T156 | arg2Of | COVID-19,links |
R150 | T156 | T158 | arg1Of | links,to |
R151 | T160 | T158 | arg2Of | degrees,to |
R152 | T160 | T159 | arg1Of | degrees,variable |
R153 | T160 | T161 | arg1Of | degrees,of |
R154 | T162 | T161 | arg2Of | inflammation,of |
R155 | T163 | T164 | arg1Of | Studies,show |
R156 | T171 | T164 | arg2Of | accelerate,show |
R157 | T171 | T165 | arg1Of | accelerate,that |
R158 | T167 | T166 | arg1Of | use,the |
R159 | T167 | T168 | arg1Of | use,of |
R160 | T169 | T168 | arg2Of | corticosteroids,of |
R161 | T167 | T170 | arg1Of | use,might |
R162 | T171 | T170 | arg2Of | accelerate,might |
R163 | T167 | T171 | arg1Of | use,accelerate |
R164 | T172 | T171 | arg2Of | recovery,accelerate |
R165 | T172 | T173 | arg1Of | recovery,from |
R166 | T174 | T173 | arg2Of | COVID-19,from |
R167 | T175 | T176 | arg1Of | There,are |
R168 | T183 | T176 | arg2Of | trials,are |
R169 | T176 | T177 | arg1Of | are,"," |
R170 | T176 | T178 | arg1Of | are,however |
R171 | T176 | T179 | arg1Of | are,"," |
R172 | T183 | T180 | arg1Of | trials,no |
R173 | T182 | T181 | arg1Of | clinical,controlled |
R174 | T183 | T182 | arg1Of | trials,clinical |
R175 | T183 | T184 | arg1Of | trials,that |
R176 | T183 | T185 | arg1Of | trials,show |
R177 | T192 | T185 | arg2Of | reduce,show |
R178 | T192 | T186 | arg1Of | reduce,whether |
R179 | T188 | T187 | arg1Of | use,the |
R180 | T188 | T189 | arg1Of | use,of |
R181 | T190 | T189 | arg2Of | corticosteroids,of |
R182 | T188 | T191 | arg1Of | use,can |
R183 | T192 | T191 | arg2Of | reduce,can |
R184 | T188 | T192 | arg1Of | use,reduce |
R185 | T194 | T192 | arg2Of | death,reduce |
R186 | T194 | T193 | arg1Of | death,COVID-19-related |
R187 | T201 | T195 | arg1Of | is,Also |
R188 | T201 | T196 | arg1Of | is,"," |
R189 | T200 | T197 | arg1Of | IL6,the |
R190 | T200 | T198 | arg1Of | IL6,pro-inflammatory |
R191 | T200 | T199 | arg1Of | IL6,cytokine |
R192 | T200 | T201 | arg1Of | IL6,is |
R193 | T204 | T201 | arg2Of | cytokine,is |
R194 | T204 | T202 | arg1Of | cytokine,the |
R195 | T204 | T203 | arg1Of | cytokine,best-documented |
R196 | T204 | T205 | arg1Of | cytokine,in |
R197 | T216 | T205 | arg2Of | and,in |
R198 | T206 | T207 | arg2Of | COVID-19,correlated |
R199 | T207 | T208 | arg1Of | correlated,with |
R200 | T209 | T208 | arg2Of | severity,with |
R201 | T209 | T210 | arg1Of | severity,"," |
R202 | T211 | T210 | arg2Of | criticality,"," |
R203 | T206 | T212 | arg1Of | COVID-19,"," |
R204 | T214 | T212 | arg2Of | load,"," |
R205 | T214 | T213 | arg1Of | load,viral |
R206 | T216 | T215 | arg1Of | and,"," |
R207 | T212 | T216 | arg1Of | ",",and |
R208 | T217 | T216 | arg2Of | prognosis,and |
R209 | T217 | T218 | arg1Of | prognosis,of |
R210 | T219 | T218 | arg2Of | patients,of |
R211 | T219 | T220 | arg1Of | patients,with |
R212 | T221 | T220 | arg2Of | COVID-19,with |
R213 | T222 | T223 | arg1Of | Tocilizumab,"," |
R214 | T226 | T223 | arg2Of | antibody,"," |
R215 | T226 | T224 | arg1Of | antibody,a |
R216 | T226 | T225 | arg1Of | antibody,monoclonal |
R217 | T226 | T227 | arg1Of | antibody,against |
R218 | T228 | T227 | arg2Of | IL6,against |
R219 | T231 | T229 | arg1Of | confer,"," |
R220 | T222 | T230 | arg1Of | Tocilizumab,could |
R221 | T231 | T230 | arg2Of | confer,could |
R222 | T222 | T231 | arg1Of | Tocilizumab,confer |
R223 | T233 | T231 | arg2Of | benefit,confer |
R224 | T233 | T232 | arg1Of | benefit,clinical |
R225 | T231 | T234 | arg1Of | confer,in |
R226 | T235 | T234 | arg2Of | patients,in |
R227 | T235 | T236 | arg1Of | patients,with |
R228 | T239 | T236 | arg2Of | levels,with |
R229 | T239 | T237 | arg1Of | levels,high |
R230 | T239 | T238 | arg1Of | levels,IL6 |
R231 | T241 | T240 | arg1Of | elements,Essential |
R232 | T241 | T242 | arg1Of | elements,that |
R233 | T247 | T242 | arg2Of | and,that |
R234 | T258 | T242 | arg3Of | have,that |
R235 | T246 | T243 | arg1Of | entry,process |
R236 | T246 | T244 | arg1Of | entry,SARS-CoV2 |
R237 | T246 | T245 | arg1Of | entry,cell |
R238 | T246 | T247 | arg1Of | entry,and |
R239 | T249 | T247 | arg2Of | characteristics,and |
R240 | T249 | T248 | arg1Of | characteristics,specific |
R241 | T249 | T250 | arg1Of | characteristics,that |
R242 | T249 | T251 | arg1Of | characteristics,allow |
R243 | T252 | T251 | arg2Of | SARS-CoV2,allow |
R244 | T254 | T251 | arg3Of | escape,allow |
R247 | T257 | T254 | arg2Of | system,escape |
R254 | T262 | T261 | arg2Of | targets,as |
R255 | T262 | T263 | arg1Of | targets,for |
R256 | T265 | T263 | arg2Of | therapy,for |
R257 | T265 | T264 | arg1Of | therapy,COVID-19 |
LitCovid-sample-PD-GO-BP-0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 454-466 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T2 | 677-682 | http://purl.obolibrary.org/obo/GO_0016265 | denotes | death |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T2 | 165-171 | Body_part | denotes | Plasma | http://purl.org/sig/ont/fma/fma62970 |
T3 | 711-719 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T4 | 747-755 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T5 | 886-894 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T6 | 1014-1018 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T7 | 1089-1102 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T6 | 23-32 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T7 | 73-81 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T8 | 155-163 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T9 | 201-209 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T10 | 243-252 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T11 | 305-313 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T12 | 422-430 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 454-466 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T14 | 544-552 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T15 | 660-668 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T16 | 759-767 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 850-858 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T18 | 1004-1013 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T19 | 1065-1074 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T20 | 1137-1145 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sample-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 454-466 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 454-466 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-93 | Sentence | denotes | The novel coronavirus, SARS-CoV2, can cause a potentially fatal disease, COVID-19, in humans. |
T12 | 94-164 | Sentence | denotes | Here, we will provide an overview of therapeutic options for COVID-19. |
T13 | 165-314 | Sentence | denotes | Plasma from patients recovered from COVID-19 that contains antibodies against SARS-CoV2 has shown promising results in patients with severe COVID-19. |
T14 | 315-406 | Sentence | denotes | Also, IVIG, combined with moderate-dose of corticosteroids, might improve patient outcomes. |
T15 | 407-467 | Sentence | denotes | Evidence links COVID-19 to variable degrees of inflammation. |
T16 | 468-553 | Sentence | denotes | Studies show that the use of corticosteroids might accelerate recovery from COVID-19. |
T17 | 554-683 | Sentence | denotes | There are, however, no controlled clinical trials that show whether the use of corticosteroids can reduce COVID-19-related death. |
T18 | 684-859 | Sentence | denotes | Also, the pro-inflammatory cytokine IL6 is the best-documented cytokine in COVID-19 correlated with severity, criticality, viral load, and prognosis of patients with COVID-19. |
T19 | 860-971 | Sentence | denotes | Tocilizumab, a monoclonal antibody against IL6, could confer clinical benefit in patients with high IL6 levels. |
T20 | 972-1154 | Sentence | denotes | Essential elements that process SARS-CoV2 cell entry and specific characteristics that allow SARS-CoV2 to escape the immune system have the potential as targets for COVID-19 therapy. |