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PMC:7205724 / 20563-21300 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
696 77-86 Species denotes SARS-CoV2 Tax:2697049
697 87-96 Disease denotes infection MESH:D007239
713 735-736 Gene denotes S Gene:43740568
714 722-723 Gene denotes S Gene:43740568
715 579-580 Gene denotes S Gene:43740568
716 520-521 Gene denotes S Gene:43740568
717 508-509 Gene denotes S Gene:43740568
718 376-377 Gene denotes S Gene:43740568
719 177-192 Species denotes transgenic mice Tax:10090
720 210-215 Species denotes human Tax:9606
721 258-261 Species denotes rat Tax:10116
722 369-375 Species denotes SARS-2 Tax:2697049
723 514-519 Species denotes SARS2 Tax:2697049
724 573-578 Species denotes SARS2 Tax:2697049
725 728-734 Species denotes SARS-2 Tax:2697049
726 463-481 Disease denotes decreased syncytia MESH:D002303
727 541-547 CellLine denotes VeroE6 CVCL:0574

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T151 141-149 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T152 216-230 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T153 269-283 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T154 408-416 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T155 548-553 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T151 77-81 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T152 87-96 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T153 358-362 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T154 369-373 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T155 503-507 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T156 562-566 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T157 717-721 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T158 728-732 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T240 19-20 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T241 59-64 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T242 107-116 http://purl.obolibrary.org/obo/CLO_0036932 denotes hybridoma
T243 210-215 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T244 432-433 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T245 453-461 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T246 541-553 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T247 593-598 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T248 686-688 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1

LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T19 216-230 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes immunoglobulin http://purl.bioontology.org/ontology/MEDDRA/10021496
T20 269-283 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes immunoglobulin http://purl.bioontology.org/ontology/MEDDRA/10021496

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T95 59-64 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T96 87-96 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T97 548-553 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T98 593-598 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T196 77-86 Species denotes SARS-CoV2 NCBItxid:2697049
T197 188-192 Species denotes mice NCBItxid:10095|NCBItxid:10088
T199 210-215 Species denotes human NCBItxid:9606
T200 258-261 Species denotes rat NCBItxid:10116|NCBItxid:10114
T202 358-362 Species denotes SARS NCBItxid:694009
T203 369-375 Species denotes SARS-2 NCBItxid:2697049
T204 503-507 Species denotes SARS NCBItxid:694009
T205 514-519 Species denotes SARS2 NCBItxid:2697049
T206 562-566 Species denotes SARS NCBItxid:694009
T207 573-578 Species denotes SARS2 NCBItxid:2697049
T208 717-721 Species denotes SARS NCBItxid:694009
T209 728-734 Species denotes SARS-2 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T166 0-18 Sentence denotes 6.1.1 Hypothesis:
T167 19-96 Sentence denotes A mAb against the binding domain of the virus can inhibit SARS-CoV2 infection
T168 97-383 Sentence denotes Recently, hybridoma supernatants containing antibody repertoires from immunized transgenic mice that express the human immunoglobulin heavy and light chains and rat origin immunoglobulin constant regions were used to detect antibodies that can cross neutralize SARS-S and SARS-2-S [26].
T169 384-604 Sentence denotes One chimeric 47D11 H2L2 antibody displayed such a cross-neutralizing activity, decreased syncytia formation induced by SARS-S and SARS2-S, and could protect VeroE6 cells against SARS-S and SARS2-S pseudotyped virus [26].
T170 605-737 Sentence denotes It may lie in its similar affinities for interacting with the same domain of the S1 subunit, i.e., S1B, of each SARS-S and SARS-2-S.

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
696 77-86 Species denotes SARS-CoV2 Tax:2697049
697 87-96 Disease denotes infection MESH:D007239
719 177-192 Species denotes transgenic mice Tax:10090
720 210-215 Species denotes human Tax:9606
721 258-261 Species denotes rat Tax:10116
722 369-375 Species denotes SARS-2 Tax:2697049
718 376-377 Gene denotes S Gene:43740568
726 463-481 Disease denotes decreased syncytia MESH:D002303
717 508-509 Gene denotes S Gene:43740568
723 514-519 Species denotes SARS2 Tax:2697049
716 520-521 Gene denotes S Gene:43740568
727 541-547 CellLine denotes VeroE6 CVCL:0574
724 573-578 Species denotes SARS2 Tax:2697049
715 579-580 Gene denotes S Gene:43740568
714 722-723 Gene denotes S Gene:43740568
725 728-734 Species denotes SARS-2 Tax:2697049
713 735-736 Gene denotes S Gene:43740568

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T2069 704-707 Protein denotes S1B https://www.uniprot.org/uniprot/P47835

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T96682 0-5 CD denotes 6.1.1
T17328 7-17 NN denotes Hypothesis
T61727 17-18 -COLON- denotes :
T32221 19-20 DT denotes A
T25878 21-24 NN denotes mAb
T8625 25-32 IN denotes against
T32030 33-36 DT denotes the
T55531 37-44 NN denotes binding
T9970 45-51 NN denotes domain
T76093 52-54 IN denotes of
T80345 55-58 DT denotes the
T93532 59-64 NN denotes virus
T16199 65-68 MD denotes can
T28417 69-76 VB denotes inhibit
T48409 77-86 NN denotes SARS-CoV2
T36310 87-96 NN denotes infection
T27915 97-105 RB denotes Recently
T56144 105-106 -COMMA- denotes ,
T55915 107-116 NN denotes hybridoma
T72012 117-129 NNS denotes supernatants
T47163 130-140 VBG denotes containing
T24138 141-149 NN denotes antibody
T98139 150-161 NNS denotes repertoires
T66535 162-166 IN denotes from
T86473 167-176 VBN denotes immunized
T66245 177-187 JJ denotes transgenic
T17100 188-192 NNS denotes mice
T85324 193-197 WDT denotes that
T55347 198-205 VBP denotes express
T14738 206-209 DT denotes the
T52540 210-215 JJ denotes human
T35586 216-230 NN denotes immunoglobulin
T72563 231-236 JJ denotes heavy
T65069 237-240 CC denotes and
T5967 241-246 JJ denotes light
T98095 247-253 NNS denotes chains
T78221 254-257 CC denotes and
T28318 258-261 NN denotes rat
T19776 262-268 NN denotes origin
T32531 269-283 NN denotes immunoglobulin
T16968 284-292 NN denotes constant
T56920 293-300 NNS denotes regions
T36716 301-305 VBD denotes were
T74827 306-310 VBN denotes used
T21382 311-313 TO denotes to
T11788 314-320 VB denotes detect
T40665 321-331 NNS denotes antibodies
T56747 332-336 WDT denotes that
T54239 337-340 MD denotes can
T71867 341-346 VB denotes cross
T35671 347-357 VB denotes neutralize
T77445 358-364 NN denotes SARS-S
T34654 365-368 CC denotes and
T83470 369-377 NN denotes SARS-2-S
T76245 378-379 -LRB- denotes [
T33581 379-381 CD denotes 26
T80577 381-382 -RRB- denotes ]
T78516 384-387 CD denotes One
T34464 388-396 JJ denotes chimeric
T13041 397-402 NN denotes 47D11
T83927 403-407 NN denotes H2L2
T57345 408-416 NN denotes antibody
T44833 417-426 VBD denotes displayed
T94688 427-431 PDT denotes such
T52983 432-433 DT denotes a
T30646 434-452 JJ denotes cross-neutralizing
T37245 453-461 NN denotes activity
T11300 461-462 -COMMA- denotes ,
T30814 463-472 VBD denotes decreased
T23282 473-481 NN denotes syncytia
T72581 482-491 NN denotes formation
T71888 492-499 VBN denotes induced
T44111 500-502 IN denotes by
T7869 503-509 NN denotes SARS-S
T80909 510-513 CC denotes and
T58127 514-521 NN denotes SARS2-S
T9479 521-522 -COMMA- denotes ,
T96346 523-526 CC denotes and
T43362 527-532 MD denotes could
T48435 533-540 VB denotes protect
T44775 541-547 NN denotes VeroE6
T25625 548-553 NNS denotes cells
T19104 554-561 IN denotes against
T51640 562-568 NN denotes SARS-S
T22676 569-572 CC denotes and
T37470 573-580 NN denotes SARS2-S
T64695 581-592 VBD denotes pseudotyped
T26978 593-598 NN denotes virus
T79137 599-600 -LRB- denotes [
T95558 600-602 CD denotes 26
T95168 602-603 -RRB- denotes ]
T45371 605-607 PRP denotes It
T75403 608-611 MD denotes may
T86603 612-615 VB denotes lie
T91829 616-618 IN denotes in
T48175 619-622 PRP-DOLLAR- denotes its
T69338 623-630 JJ denotes similar
T68140 631-641 NNS denotes affinities
T76951 642-645 IN denotes for
T38362 646-657 VBG denotes interacting
T39715 658-662 IN denotes with
T48378 663-666 DT denotes the
T63623 667-671 JJ denotes same
T2491 672-678 NN denotes domain
T57621 679-681 IN denotes of
T77993 682-685 DT denotes the
T52886 686-688 NN denotes S1
T27554 689-696 NN denotes subunit
T41139 696-697 -COMMA- denotes ,
T99819 698-702 FW denotes i.e.
T40027 702-703 -COMMA- denotes ,
T73637 704-707 NN denotes S1B
T71055 707-708 -COMMA- denotes ,
T88888 709-711 IN denotes of
T40209 712-716 DT denotes each
T2572 717-723 NN denotes SARS-S
T97128 724-727 CC denotes and
T91104 728-736 NN denotes SARS-2-S
R32719 T17328 T96682 arg1Of Hypothesis,6.1.1
R34441 T17328 T61727 arg1Of Hypothesis,:
R7667 T25878 T32221 arg1Of mAb,A
R91773 T25878 T8625 arg1Of mAb,against
R23833 T9970 T8625 arg2Of domain,against
R92213 T9970 T32030 arg1Of domain,the
R57443 T9970 T55531 arg1Of domain,binding
R31979 T9970 T76093 arg1Of domain,of
R76879 T93532 T76093 arg2Of virus,of
R54102 T93532 T80345 arg1Of virus,the
R20587 T25878 T16199 arg1Of mAb,can
R25119 T28417 T16199 arg2Of inhibit,can
R58250 T17328 T16199 modOf Hypothesis,can
R15396 T25878 T28417 arg1Of mAb,inhibit
R9435 T36310 T28417 arg2Of infection,inhibit
R6804 T36310 T48409 arg1Of infection,SARS-CoV2
R33983 T74827 T27915 arg1Of used,Recently
R66835 T74827 T56144 arg1Of used,","
R79461 T72012 T55915 arg1Of supernatants,hybridoma
R93366 T72012 T47163 arg1Of supernatants,containing
R25704 T98139 T47163 arg2Of repertoires,containing
R90990 T98139 T24138 arg1Of repertoires,antibody
R94676 T98139 T66535 arg1Of repertoires,from
R63011 T17100 T66535 arg2Of mice,from
R10738 T17100 T86473 arg2Of mice,immunized
R74916 T17100 T66245 arg1Of mice,transgenic
R8726 T98139 T85324 arg1Of repertoires,that
R22914 T98139 T55347 arg1Of repertoires,express
R91506 T78221 T55347 arg2Of and,express
R63116 T78221 T14738 arg1Of and,the
R50898 T98095 T52540 arg1Of chains,human
R6996 T98095 T35586 arg1Of chains,immunoglobulin
R54748 T98095 T72563 arg1Of chains,heavy
R94533 T72563 T65069 arg1Of heavy,and
R51991 T5967 T65069 arg2Of light,and
R10518 T98095 T5967 arg1Of chains,light
R78842 T98095 T78221 arg1Of chains,and
R33937 T56920 T78221 arg2Of regions,and
R92294 T56920 T28318 arg1Of regions,rat
R87268 T56920 T19776 arg1Of regions,origin
R7737 T56920 T32531 arg1Of regions,immunoglobulin
R98342 T56920 T16968 arg1Of regions,constant
R65646 T72012 T36716 arg1Of supernatants,were
R67139 T74827 T36716 arg2Of used,were
R67837 T72012 T74827 arg2Of supernatants,used
R69341 T11788 T74827 arg3Of detect,used
R12801 T11788 T21382 arg1Of detect,to
R52958 T40665 T11788 arg2Of antibodies,detect
R77806 T40665 T56747 arg1Of antibodies,that
R37476 T40665 T54239 arg1Of antibodies,can
R87983 T35671 T54239 arg2Of neutralize,can
R24714 T40665 T71867 arg1Of antibodies,cross
R29418 T35671 T71867 arg2Of neutralize,cross
R8917 T40665 T35671 arg1Of antibodies,neutralize
R70086 T34654 T35671 arg2Of and,neutralize
R88560 T77445 T34654 arg1Of SARS-S,and
R74668 T83470 T34654 arg2Of SARS-2-S,and
R89642 T35671 T76245 arg1Of neutralize,[
R10178 T33581 T76245 arg2Of 26,[
R12224 T80577 T76245 arg3Of ],[
R55425 T57345 T78516 arg1Of antibody,One
R85824 T57345 T34464 arg1Of antibody,chimeric
R91166 T57345 T13041 arg1Of antibody,47D11
R74139 T57345 T83927 arg1Of antibody,H2L2
R37082 T57345 T44833 arg1Of antibody,displayed
R42165 T37245 T44833 arg2Of activity,displayed
R8404 T37245 T94688 arg1Of activity,such
R58851 T37245 T52983 arg1Of activity,a
R6725 T37245 T30646 arg1Of activity,cross-neutralizing
R48595 T44833 T11300 arg1Of displayed,","
R75181 T30814 T11300 arg2Of decreased,","
R32317 T57345 T30814 arg1Of antibody,decreased
R66912 T72581 T30814 arg2Of formation,decreased
R2953 T72581 T23282 arg1Of formation,syncytia
R53752 T80909 T71888 arg1Of and,induced
R39715 T72581 T71888 arg2Of formation,induced
R78219 T80909 T44111 arg2Of and,by
R96452 T7869 T80909 arg1Of SARS-S,and
R84017 T58127 T80909 arg2Of SARS2-S,and
R48482 T96346 T9479 arg1Of and,","
R37253 T11300 T96346 arg1Of ",",and
R96321 T48435 T96346 arg2Of protect,and
R73215 T57345 T43362 arg1Of antibody,could
R33694 T48435 T43362 arg2Of protect,could
R79302 T57345 T48435 arg1Of antibody,protect
R44320 T25625 T48435 arg2Of cells,protect
R54339 T25625 T44775 arg1Of cells,VeroE6
R74716 T48435 T19104 arg1Of protect,against
R67161 T22676 T19104 arg2Of and,against
R67960 T51640 T22676 arg1Of SARS-S,and
R58716 T37470 T22676 arg2Of SARS2-S,and
R42573 T22676 T64695 arg2Of and,pseudotyped
R23893 T26978 T64695 arg3Of virus,pseudotyped
R62516 T26978 T79137 arg1Of virus,[
R68991 T95558 T79137 arg2Of 26,[
R21425 T95168 T79137 arg3Of ],[
R57799 T45371 T75403 arg1Of It,may
R22045 T86603 T75403 arg2Of lie,may
R27208 T45371 T86603 arg1Of It,lie
R30853 T86603 T91829 arg1Of lie,in
R8563 T68140 T91829 arg2Of affinities,in
R84051 T68140 T48175 arg1Of affinities,its
R54251 T68140 T69338 arg1Of affinities,similar
R17475 T68140 T76951 arg1Of affinities,for
R24043 T38362 T76951 arg2Of interacting,for
R92728 T38362 T39715 arg1Of interacting,with
R17122 T2491 T39715 arg2Of domain,with
R47571 T2491 T48378 arg1Of domain,the
R29816 T2491 T63623 arg1Of domain,same
R3874 T2491 T57621 arg1Of domain,of
R51485 T27554 T57621 arg2Of subunit,of
R73905 T27554 T77993 arg1Of subunit,the
R30509 T27554 T52886 arg1Of subunit,S1
R24972 T68140 T41139 arg1Of affinities,","
R48015 T68140 T99819 arg1Of affinities,i.e.
R85163 T73637 T99819 arg2Of S1B,i.e.
R34990 T99819 T40027 arg1Of i.e.,","
R84082 T68140 T71055 arg1Of affinities,","
R73965 T68140 T88888 arg1Of affinities,of
R44270 T97128 T88888 arg2Of and,of
R2062 T97128 T40209 arg1Of and,each
R35318 T2572 T97128 arg1Of SARS-S,and
R89938 T91104 T97128 arg2Of SARS-2-S,and

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T30 482-491 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T151 141-149 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T152 216-230 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T153 269-283 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T154 408-416 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T155 548-553 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T146 77-86 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T147 87-96 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T148 358-362 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T149 369-373 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T150 503-507 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T151 562-566 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T152 717-721 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T153 728-732 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T26 482-491 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T26 482-491 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T166 0-18 Sentence denotes 6.1.1 Hypothesis:
T167 19-96 Sentence denotes A mAb against the binding domain of the virus can inhibit SARS-CoV2 infection
T168 97-383 Sentence denotes Recently, hybridoma supernatants containing antibody repertoires from immunized transgenic mice that express the human immunoglobulin heavy and light chains and rat origin immunoglobulin constant regions were used to detect antibodies that can cross neutralize SARS-S and SARS-2-S [26].
T169 384-604 Sentence denotes One chimeric 47D11 H2L2 antibody displayed such a cross-neutralizing activity, decreased syncytia formation induced by SARS-S and SARS2-S, and could protect VeroE6 cells against SARS-S and SARS2-S pseudotyped virus [26].
T170 605-737 Sentence denotes It may lie in its similar affinities for interacting with the same domain of the S1 subunit, i.e., S1B, of each SARS-S and SARS-2-S.