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PMC:7205724 / 19472-20478 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
665 321-330 Species denotes SARS-CoV2 Tax:2697049
679 473-477 Gene denotes ACE2 Gene:103231639
680 371-380 Species denotes SARS-CoV2 Tax:2697049
681 506-515 Species denotes SARS-CoV2 Tax:2697049
682 584-592 Species denotes SARS-CoV Tax:694009
683 666-675 Species denotes SARS-CoV2 Tax:2697049
684 734-742 Species denotes SARS-CoV Tax:694009
685 843-852 Species denotes SARS-CoV2 Tax:2697049
686 857-865 Species denotes SARS-CoV Tax:694009
687 360-369 Disease denotes infection MESH:D007239
688 516-525 Disease denotes infection MESH:D007239
689 714-723 Disease denotes infection MESH:D007239
690 804-813 Disease denotes infection MESH:D007239
691 449-451 CellLine denotes E6 CVCL:4582

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T147 452-457 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T148 942-950 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T139 321-325 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T140 360-369 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 371-375 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T142 506-510 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T143 516-525 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T144 584-592 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T145 666-670 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T146 714-723 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T147 734-742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T148 804-813 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T149 843-847 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T150 857-865 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T231 54-55 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T232 101-102 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 349-351 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T234 444-457 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T235 703-705 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T236 793-795 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T237 960-967 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T166 942-950 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T82 143-154 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T83 194-210 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T84 331-342 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T85 360-369 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T86 381-392 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T87 452-457 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T88 491-502 http://purl.obolibrary.org/obo/IDO_0000467 denotes susceptible
T89 516-525 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T90 559-570 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T91 676-687 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T92 714-723 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T93 804-813 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T94 960-967 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T108 942-950 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T186 321-330 Species denotes SARS-CoV2 NCBItxid:2697049
T187 371-380 Species denotes SARS-CoV2 NCBItxid:2697049
T188 506-515 Species denotes SARS-CoV2 NCBItxid:2697049
T189 584-592 Species denotes SARS-CoV NCBItxid:694009
T190 666-675 Species denotes SARS-CoV2 NCBItxid:2697049
T191 734-742 Species denotes SARS-CoV NCBItxid:694009
T192 843-852 Species denotes SARS-CoV2 NCBItxid:2697049
T193 857-865 Species denotes SARS-CoV NCBItxid:694009
T194 960-967 Species denotes viruses NCBItxid:10239

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T154 0-25 Sentence denotes 5 Recombinant type I IFN
T155 27-83 Sentence denotes 5.1 Hypothesis: IFNs play a role in anti-viral immunity
T156 84-257 Sentence denotes Type I IFNs play a primary role in the inhibition of viral replication through the coordination of anti-viral immune responses and modulation of inflammatory responses [24].
T157 259-273 Sentence denotes 5.2 Rational:
T158 274-342 Sentence denotes Recombinant type I IFN can effectively inhibit SARS-CoV2 replication
T159 343-531 Sentence denotes In 24–48 h after infection, SARS-CoV2 replication reaches titer that causes the cytopathic effect in Vero E6 cells, which express ACE2 and thus are susceptible to SARS-CoV2 infection [25].
T160 532-598 Sentence denotes It is similar to the viral replication kinetics for SARS-CoV [25].
T161 599-729 Sentence denotes Pretreatment with recombinant type I IFN could effectively inhibit SARS-CoV2 replication at both 24 and 48 h after infection [25].
T162 730-819 Sentence denotes For SARS-CoV, such an effect was present at 24 h but absent at 48 h after infection [25].
T163 820-1006 Sentence denotes The difference between SARS-CoV2 and SARS-CoV in response to type I IFN treatment may be due to differences in structural proteins of these viruses, including NSP3, ORF3b, and ORF6 [25].

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
665 321-330 Species denotes SARS-CoV2 Tax:2697049
687 360-369 Disease denotes infection MESH:D007239
680 371-380 Species denotes SARS-CoV2 Tax:2697049
691 449-451 CellLine denotes E6 CVCL:4582
679 473-477 Gene denotes ACE2 Gene:103231639
681 506-515 Species denotes SARS-CoV2 Tax:2697049
688 516-525 Disease denotes infection MESH:D007239
682 584-592 Species denotes SARS-CoV Tax:694009
683 666-675 Species denotes SARS-CoV2 Tax:2697049
689 714-723 Disease denotes infection MESH:D007239
684 734-742 Species denotes SARS-CoV Tax:694009
690 804-813 Disease denotes infection MESH:D007239
685 843-852 Species denotes SARS-CoV2 Tax:2697049
686 857-865 Species denotes SARS-CoV Tax:694009

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T1989 931-950 Protein denotes structural proteins https://www.uniprot.org/uniprot/Q6LEG6|https://www.uniprot.org/uniprot/Q04766|https://www.uniprot.org/uniprot/Q04765
T1992 979-983 Protein denotes NSP3 https://www.uniprot.org/uniprot/Q9QNA7|https://www.uniprot.org/uniprot/Q9PY95|https://www.uniprot.org/uniprot/Q9ICB2|https://www.uniprot.org/uniprot/Q91ME7|https://www.uniprot.org/uniprot/Q8UZL8|https://www.uniprot.org/uniprot/Q8B6X8|https://www.uniprot.org/uniprot/Q8B6X7|https://www.uniprot.org/uniprot/Q86504|https://www.uniprot.org/uniprot/Q86196|https://www.uniprot.org/uniprot/Q85014|https://www.uniprot.org/uniprot/Q82054|https://www.uniprot.org/uniprot/Q82053|https://www.uniprot.org/uniprot/Q82052|https://www.uniprot.org/uniprot/Q82051|https://www.uniprot.org/uniprot/Q82050|https://www.uniprot.org/uniprot/Q82049|https://www.uniprot.org/uniprot/Q65701|https://www.uniprot.org/uniprot/Q5Y9A9|https://www.uniprot.org/uniprot/Q5K037|https://www.uniprot.org/uniprot/Q45UF3|https://www.uniprot.org/uniprot/Q3ZK63|https://www.uniprot.org/uniprot/Q27PP2|https://www.uniprot.org/uniprot/Q0H8C1|https://www.uniprot.org/uniprot/Q00721|https://www.uniprot.org/uniprot/P34717|https://www.uniprot.org/uniprot/P27586|https://www.uniprot.org/uniprot/P04514|https://www.uniprot.org/uniprot/P03536|https://www.uniprot.org/uniprot/B3SRX7|https://www.uniprot.org/uniprot/B3SRW9|https://www.uniprot.org/uniprot/B3SRV3|https://www.uniprot.org/uniprot/B3SRU5|https://www.uniprot.org/uniprot/B3SRS9|https://www.uniprot.org/uniprot/B3SRS1|https://www.uniprot.org/uniprot/B3SRR3|https://www.uniprot.org/uniprot/B3SRQ5|https://www.uniprot.org/uniprot/B2BRG4|https://www.uniprot.org/uniprot/A4ZCW4|https://www.uniprot.org/uniprot/A3DSK9|https://www.uniprot.org/uniprot/A2T3N5|https://www.uniprot.org/uniprot/A1YTU9
T2033 996-1000 Protein denotes ORF6 https://www.uniprot.org/uniprot/P51707|https://www.uniprot.org/uniprot/P42541|https://www.uniprot.org/uniprot/P0DTC6

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T52733 0-1 CD denotes 5
T83488 3-14 JJ denotes Recombinant
T93217 15-19 NN denotes type
T64716 20-21 CD denotes I
T68579 22-25 NN denotes IFN
T12001 27-30 CD denotes 5.1
T9969 32-42 NN denotes Hypothesis
T15939 42-43 -COLON- denotes :
T64893 44-48 NNS denotes IFNs
T64532 49-53 VBP denotes play
T66496 54-55 DT denotes a
T99130 56-60 NN denotes role
T16405 61-63 IN denotes in
T11399 64-74 JJ denotes anti-viral
T89696 75-83 NN denotes immunity
T96681 84-88 NN denotes Type
T4789 89-90 CD denotes I
T85645 91-95 NNS denotes IFNs
T76626 96-100 VBP denotes play
T51847 101-102 DT denotes a
T51548 103-110 JJ denotes primary
T78533 111-115 NN denotes role
T65875 116-118 IN denotes in
T16934 119-122 DT denotes the
T59480 123-133 NN denotes inhibition
T64120 134-136 IN denotes of
T42209 137-142 JJ denotes viral
T92412 143-154 NN denotes replication
T19053 155-162 IN denotes through
T85138 163-166 DT denotes the
T89603 167-179 NN denotes coordination
T52542 180-182 IN denotes of
T13645 183-193 JJ denotes anti-viral
T39632 194-200 JJ denotes immune
T42144 201-210 NNS denotes responses
T54149 211-214 CC denotes and
T13001 215-225 NN denotes modulation
T2287 226-228 IN denotes of
T72730 229-241 JJ denotes inflammatory
T37912 242-251 NNS denotes responses
T64464 252-253 -LRB- denotes [
T89396 253-255 CD denotes 24
T17915 255-256 -RRB- denotes ]
T44068 259-262 CD denotes 5.2
T95208 264-272 NNP denotes Rational
T91019 272-273 -COLON- denotes :
T95927 274-285 JJ denotes Recombinant
T3712 286-290 NN denotes type
T46872 291-292 CD denotes I
T95232 293-296 NN denotes IFN
T83801 297-300 MD denotes can
T31121 301-312 RB denotes effectively
T50200 313-320 VB denotes inhibit
T51383 321-330 NN denotes SARS-CoV2
T97492 331-342 NN denotes replication
T96177 343-345 IN denotes In
T72452 346-353 NN denotes 24–48 h
T50493 354-359 IN denotes after
T17096 360-369 NN denotes infection
T97012 369-370 -COMMA- denotes ,
T67170 371-380 NN denotes SARS-CoV2
T9761 381-392 NN denotes replication
T69880 393-400 VBZ denotes reaches
T9709 401-406 NN denotes titer
T49785 407-411 WDT denotes that
T71708 412-418 VBZ denotes causes
T52777 419-422 DT denotes the
T56623 423-433 JJ denotes cytopathic
T87850 434-440 NN denotes effect
T47272 441-443 IN denotes in
T71726 444-448 NN denotes Vero
T42629 449-451 NN denotes E6
T73531 452-457 NNS denotes cells
T60353 457-458 -COMMA- denotes ,
T83400 459-464 WDT denotes which
T80948 465-472 VBP denotes express
T12338 473-477 NN denotes ACE2
T60658 478-481 CC denotes and
T41368 482-486 RB denotes thus
T89464 487-490 VBP denotes are
T62340 491-502 JJ denotes susceptible
T6873 503-505 TO denotes to
T68175 506-515 NN denotes SARS-CoV2
T16296 516-525 NN denotes infection
T12529 526-527 -LRB- denotes [
T55131 527-529 CD denotes 25
T28678 529-530 -RRB- denotes ]
T52876 532-534 PRP denotes It
T21084 535-537 VBZ denotes is
T70918 538-545 JJ denotes similar
T20327 546-548 TO denotes to
T13471 549-552 DT denotes the
T26039 553-558 JJ denotes viral
T64125 559-570 NN denotes replication
T62855 571-579 NNS denotes kinetics
T68614 580-583 IN denotes for
T64958 584-592 NN denotes SARS-CoV
T62199 593-594 -LRB- denotes [
T27403 594-596 CD denotes 25
T34963 596-597 -RRB- denotes ]
T49689 599-611 NN denotes Pretreatment
T74739 612-616 IN denotes with
T62356 617-628 JJ denotes recombinant
T67333 629-633 NN denotes type
T31833 634-635 CD denotes I
T78772 636-639 NN denotes IFN
T57406 640-645 MD denotes could
T5100 646-657 RB denotes effectively
T32529 658-665 VB denotes inhibit
T31501 666-675 NN denotes SARS-CoV2
T43668 676-687 NN denotes replication
T86722 688-690 IN denotes at
T26971 691-695 CC denotes both
T35627 696-698 CD denotes 24
T29701 699-702 CC denotes and
T48153 703-707 NN denotes 48 h
T93874 708-713 IN denotes after
T7550 714-723 NN denotes infection
T23827 724-725 -LRB- denotes [
T6071 725-727 CD denotes 25
T91011 727-728 -RRB- denotes ]
T51029 730-733 IN denotes For
T64526 734-742 NN denotes SARS-CoV
T41819 742-743 -COMMA- denotes ,
T5764 744-748 PDT denotes such
T79954 749-751 DT denotes an
T48924 752-758 NN denotes effect
T40034 759-762 VBD denotes was
T1935 763-770 JJ denotes present
T31311 771-773 IN denotes at
T94385 774-778 CD denotes 24 h
T84543 779-782 CC denotes but
T64490 783-789 JJ denotes absent
T33679 790-792 IN denotes at
T68271 793-797 NN denotes 48 h
T69307 798-803 IN denotes after
T51672 804-813 NN denotes infection
T85433 814-815 -LRB- denotes [
T72350 815-817 CD denotes 25
T63406 817-818 -RRB- denotes ]
T46096 820-823 DT denotes The
T71403 824-834 NN denotes difference
T17651 835-842 IN denotes between
T77482 843-852 NN denotes SARS-CoV2
T6733 853-856 CC denotes and
T6622 857-865 NN denotes SARS-CoV
T66580 866-868 IN denotes in
T74975 869-877 NN denotes response
T1853 878-880 TO denotes to
T87892 881-885 NN denotes type
T83308 886-887 CD denotes I
T81934 888-891 NN denotes IFN
T42652 892-901 NN denotes treatment
T91527 902-905 MD denotes may
T42839 906-908 VB denotes be
T98810 909-912 JJ denotes due
T31126 913-915 TO denotes to
T23141 916-927 NNS denotes differences
T45488 928-930 IN denotes in
T39296 931-941 JJ denotes structural
T12723 942-950 NNS denotes proteins
T40582 951-953 IN denotes of
T48639 954-959 DT denotes these
T20513 960-967 NNS denotes viruses
T37519 967-968 -COMMA- denotes ,
T18237 969-978 VBG denotes including
T17094 979-983 NN denotes NSP3
T86991 983-984 -COMMA- denotes ,
T14810 985-990 NN denotes ORF3b
T9269 990-991 -COMMA- denotes ,
T18064 992-995 CC denotes and
T40695 996-1000 NN denotes ORF6
T59456 1001-1002 -LRB- denotes [
T34145 1002-1004 CD denotes 25
T98303 1004-1005 -RRB- denotes ]
R49535 T99130 T66496 arg1Of role,a
R82137 T64532 T16405 arg1Of play,in
R93910 T89696 T16405 arg2Of immunity,in
R53989 T89696 T11399 arg1Of immunity,anti-viral
R24484 T85645 T96681 arg1Of IFNs,Type
R82882 T85645 T4789 arg1Of IFNs,I
R80452 T85645 T76626 arg1Of IFNs,play
R9839 T78533 T76626 arg2Of role,play
R78526 T78533 T51847 arg1Of role,a
R6704 T78533 T51548 arg1Of role,primary
R74996 T76626 T65875 arg1Of play,in
R31420 T69880 T96177 arg1Of reaches,In
R8938 T72452 T96177 arg2Of 24–48 h,In
R22070 T72452 T50493 arg1Of 24–48 h,after
R29558 T17096 T50493 arg2Of infection,after
R81743 T69880 T97012 arg1Of reaches,","
R54619 T9761 T67170 arg1Of replication,SARS-CoV2
R28733 T9761 T69880 arg1Of replication,reaches
R54888 T9709 T69880 arg2Of titer,reaches
R54019 T9709 T49785 arg1Of titer,that
R2019 T9709 T71708 arg1Of titer,causes
R69166 T87850 T71708 arg2Of effect,causes
R70600 T87850 T52777 arg1Of effect,the
R54949 T87850 T56623 arg1Of effect,cytopathic
R44193 T68579 T52733 arg1Of IFN,5
R5826 T68579 T83488 arg1Of IFN,Recombinant
R80234 T68579 T93217 arg1Of IFN,type
R96417 T68579 T64716 arg1Of IFN,I
R50529 T9969 T12001 arg1Of Hypothesis,5.1
R73746 T9969 T15939 arg1Of Hypothesis,:
R48761 T64532 T15939 arg2Of play,:
R11011 T64893 T64532 arg1Of IFNs,play
R56923 T99130 T64532 arg2Of role,play
R7798 T59480 T65875 arg2Of inhibition,in
R26292 T59480 T16934 arg1Of inhibition,the
R3018 T59480 T64120 arg1Of inhibition,of
R88840 T92412 T64120 arg2Of replication,of
R43315 T92412 T42209 arg1Of replication,viral
R45666 T76626 T19053 arg1Of play,through
R41012 T54149 T19053 arg2Of and,through
R49957 T54149 T85138 arg1Of and,the
R10665 T89603 T52542 arg1Of coordination,of
R3748 T42144 T52542 arg2Of responses,of
R96444 T42144 T13645 arg1Of responses,anti-viral
R11270 T42144 T39632 arg1Of responses,immune
R93882 T89603 T54149 arg1Of coordination,and
R64051 T13001 T54149 arg2Of modulation,and
R35227 T13001 T2287 arg1Of modulation,of
R46504 T37912 T2287 arg2Of responses,of
R49745 T37912 T72730 arg1Of responses,inflammatory
R59902 T76626 T64464 arg1Of play,[
R73394 T89396 T64464 arg2Of 24,[
R27076 T17915 T64464 arg3Of ],[
R12484 T95208 T44068 arg1Of Rational,5.2
R35124 T95208 T91019 arg1Of Rational,:
R50751 T95232 T95927 arg1Of IFN,Recombinant
R74572 T95232 T3712 arg1Of IFN,type
R58753 T95232 T46872 arg1Of IFN,I
R16030 T95232 T83801 arg1Of IFN,can
R78959 T50200 T83801 arg2Of inhibit,can
R77408 T50200 T31121 arg1Of inhibit,effectively
R98880 T95232 T50200 arg1Of IFN,inhibit
R90780 T97492 T50200 arg2Of replication,inhibit
R70416 T97492 T51383 arg1Of replication,SARS-CoV2
R67236 T71708 T47272 arg1Of causes,in
R90604 T73531 T47272 arg2Of cells,in
R51483 T73531 T71726 arg1Of cells,Vero
R13941 T73531 T42629 arg1Of cells,E6
R47369 T73531 T60353 arg1Of cells,","
R77344 T73531 T83400 arg1Of cells,which
R51996 T73531 T80948 arg1Of cells,express
R29937 T12338 T80948 arg2Of ACE2,express
R56727 T80948 T60658 arg1Of express,and
R89880 T89464 T60658 arg2Of are,and
R41139 T89464 T41368 arg1Of are,thus
R40674 T73531 T89464 arg1Of cells,are
R2313 T62340 T89464 arg2Of susceptible,are
R71574 T73531 T62340 arg1Of cells,susceptible
R18320 T62340 T6873 arg1Of susceptible,to
R10483 T16296 T6873 arg2Of infection,to
R64279 T16296 T68175 arg1Of infection,SARS-CoV2
R82228 T89464 T12529 arg1Of are,[
R14351 T55131 T12529 arg2Of 25,[
R89760 T28678 T12529 arg3Of ],[
R98431 T52876 T21084 arg1Of It,is
R14327 T70918 T21084 arg2Of similar,is
R4320 T52876 T70918 arg1Of It,similar
R34375 T70918 T20327 arg1Of similar,to
R71339 T62855 T20327 arg2Of kinetics,to
R35190 T62855 T13471 arg1Of kinetics,the
R34673 T62855 T26039 arg1Of kinetics,viral
R67158 T62855 T64125 arg1Of kinetics,replication
R90913 T70918 T68614 arg1Of similar,for
R5275 T64958 T68614 arg2Of SARS-CoV,for
R43068 T64958 T62199 arg1Of SARS-CoV,[
R10807 T27403 T62199 arg2Of 25,[
R91008 T34963 T62199 arg3Of ],[
R68776 T49689 T74739 arg1Of Pretreatment,with
R59690 T78772 T74739 arg2Of IFN,with
R64010 T78772 T62356 arg1Of IFN,recombinant
R73596 T78772 T67333 arg1Of IFN,type
R44930 T78772 T31833 arg1Of IFN,I
R49184 T49689 T57406 arg1Of Pretreatment,could
R80908 T32529 T57406 arg2Of inhibit,could
R7756 T32529 T5100 arg1Of inhibit,effectively
R41655 T49689 T32529 arg1Of Pretreatment,inhibit
R47659 T43668 T32529 arg2Of replication,inhibit
R36370 T43668 T31501 arg1Of replication,SARS-CoV2
R34213 T32529 T86722 arg1Of inhibit,at
R26206 T29701 T86722 arg2Of and,at
R82903 T29701 T26971 arg1Of and,both
R75547 T35627 T29701 arg1Of 24,and
R90827 T48153 T29701 arg2Of 48 h,and
R69068 T32529 T93874 arg1Of inhibit,after
R47977 T7550 T93874 arg2Of infection,after
R38076 T7550 T23827 arg1Of infection,[
R72421 T6071 T23827 arg2Of 25,[
R2860 T91011 T23827 arg3Of ],[
R21012 T40034 T51029 arg1Of was,For
R42425 T64526 T51029 arg2Of SARS-CoV,For
R88091 T40034 T41819 arg1Of was,","
R54495 T48924 T5764 arg1Of effect,such
R26625 T48924 T79954 arg1Of effect,an
R41534 T48924 T40034 arg1Of effect,was
R24883 T84543 T40034 arg2Of but,was
R86398 T48924 T1935 arg1Of effect,present
R81876 T1935 T31311 arg1Of present,at
R72270 T94385 T31311 arg2Of 24 h,at
R12851 T1935 T84543 arg1Of present,but
R60363 T64490 T84543 arg2Of absent,but
R81621 T48924 T64490 arg1Of effect,absent
R79664 T84543 T33679 arg1Of but,at
R9487 T68271 T33679 arg2Of 48 h,at
R71731 T68271 T69307 arg1Of 48 h,after
R56025 T51672 T69307 arg2Of infection,after
R2152 T51672 T85433 arg1Of infection,[
R22284 T72350 T85433 arg2Of 25,[
R9566 T63406 T85433 arg3Of ],[
R51347 T71403 T46096 arg1Of difference,The
R4839 T71403 T17651 arg1Of difference,between
R32316 T6733 T17651 arg2Of and,between
R84108 T77482 T6733 arg1Of SARS-CoV2,and
R18562 T6622 T6733 arg2Of SARS-CoV,and
R2587 T6733 T66580 arg1Of and,in
R24267 T74975 T66580 arg2Of response,in
R82007 T74975 T1853 arg1Of response,to
R35751 T42652 T1853 arg2Of treatment,to
R70872 T42652 T87892 arg1Of treatment,type
R16675 T42652 T83308 arg1Of treatment,I
R93961 T42652 T81934 arg1Of treatment,IFN
R17630 T71403 T91527 arg1Of difference,may
R18684 T42839 T91527 arg2Of be,may
R22926 T71403 T42839 arg1Of difference,be
R74216 T31126 T42839 arg2Of to,be
R18552 T31126 T98810 arg1Of to,due
R78491 T71403 T31126 arg1Of difference,to
R99441 T23141 T31126 arg2Of differences,to
R87106 T23141 T45488 arg1Of differences,in
R95354 T12723 T45488 arg2Of proteins,in
R28120 T12723 T39296 arg1Of proteins,structural
R78454 T12723 T40582 arg1Of proteins,of
R26738 T20513 T40582 arg2Of viruses,of
R35077 T20513 T48639 arg1Of viruses,these
R70559 T12723 T37519 arg1Of proteins,","
R50810 T12723 T18237 arg1Of proteins,including
R8147 T18064 T18237 arg2Of and,including
R72409 T17094 T86991 arg1Of NSP3,","
R12802 T14810 T86991 arg2Of ORF3b,","
R29123 T18064 T9269 arg1Of and,","
R68379 T86991 T18064 arg1Of ",",and
R4978 T40695 T18064 arg2Of ORF6,and
R22872 T18064 T59456 arg1Of and,[
R60583 T34145 T59456 arg2Of 25,[
R50503 T98303 T59456 arg3Of ],[

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T22 123-154 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T23 137-154 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T24 137-154 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T25 194-210 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T26 229-251 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T27 553-570 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T28 553-570 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T29 869-891 http://purl.obolibrary.org/obo/GO_0034340 denotes response to type I IFN

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T147 452-457 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T148 942-950 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T134 321-330 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T135 360-369 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T136 371-380 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T137 506-515 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T138 516-525 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T139 584-592 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T140 666-675 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T141 714-723 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T142 734-742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T143 804-813 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T144 843-852 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T145 857-865 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T18 123-154 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T19 137-154 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T20 137-154 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T21 194-210 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T22 229-251 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T23 553-570 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T24 553-570 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T25 869-891 http://purl.obolibrary.org/obo/GO_0034340 denotes response to type I IFN

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T18 123-154 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T19 137-154 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T20 137-154 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T21 194-210 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T22 229-251 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T23 553-570 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T24 553-570 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T25 869-891 http://purl.obolibrary.org/obo/GO_0034340 denotes response to type I IFN

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T154 0-25 Sentence denotes 5 Recombinant type I IFN
T155 27-83 Sentence denotes 5.1 Hypothesis: IFNs play a role in anti-viral immunity
T156 84-257 Sentence denotes Type I IFNs play a primary role in the inhibition of viral replication through the coordination of anti-viral immune responses and modulation of inflammatory responses [24].
T157 259-273 Sentence denotes 5.2 Rational:
T158 274-342 Sentence denotes Recombinant type I IFN can effectively inhibit SARS-CoV2 replication
T159 343-531 Sentence denotes In 24–48 h after infection, SARS-CoV2 replication reaches titer that causes the cytopathic effect in Vero E6 cells, which express ACE2 and thus are susceptible to SARS-CoV2 infection [25].
T160 532-598 Sentence denotes It is similar to the viral replication kinetics for SARS-CoV [25].
T161 599-729 Sentence denotes Pretreatment with recombinant type I IFN could effectively inhibit SARS-CoV2 replication at both 24 and 48 h after infection [25].
T162 730-819 Sentence denotes For SARS-CoV, such an effect was present at 24 h but absent at 48 h after infection [25].
T163 820-1006 Sentence denotes The difference between SARS-CoV2 and SARS-CoV in response to type I IFN treatment may be due to differences in structural proteins of these viruses, including NSP3, ORF3b, and ORF6 [25].

2_test

Id Subject Object Predicate Lexical cue
32413736-10754318-48112978 253-255 10754318 denotes 24
T95987 253-255 10754318 denotes 24