PMC:7205724 / 14391-15097
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
456 | 340-344 | Gene | denotes | ACE2 | Gene:59272 |
457 | 434-438 | Gene | denotes | ACE2 | Gene:59272 |
458 | 704-705 | Gene | denotes | S | Gene:43740568 |
459 | 663-664 | Gene | denotes | S | Gene:43740568 |
460 | 194-195 | Gene | denotes | S | Gene:43740568 |
461 | 0-8 | Species | denotes | SARS-CoV | Tax:694009 |
462 | 13-22 | Species | denotes | SARS-CoV2 | Tax:2697049 |
463 | 530-535 | Species | denotes | human | Tax:9606 |
464 | 656-662 | Species | denotes | SARS-2 | Tax:2697049 |
465 | 536-552 | Disease | denotes | embryonic kidney | MESH:D007674 |
466 | 554-557 | CellLine | denotes | HEK | CVCL:M624 |
467 | 570-575 | CellLine | denotes | 293 T | CVCL:0063 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T106 | 165-175 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T107 | 196-203 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T108 | 256-261 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T109 | 546-552 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T110 | 559-563 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T111 | 634-639 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T112 | 677-682 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T8 | 546-552 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T89 | 0-8 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T90 | 13-17 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T91 | 656-660 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T92 | 699-703 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T156 | 58-67 | http://purl.obolibrary.org/obo/UBERON_0007651 | denotes | junctions |
T157 | 124-125 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T158 | 205-206 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T159 | 215-217 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T160 | 215-217 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T161 | 234-235 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T162 | 256-261 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T163 | 358-360 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T164 | 530-535 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T165 | 536-552 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | embryonic kidney |
T166 | 559-568 | http://purl.obolibrary.org/obo/CLO_0000031 | denotes | cell line |
T167 | 570-575 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293 T |
T168 | 570-575 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293 T |
T169 | 570-575 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293 T |
T170 | 577-580 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T171 | 592-593 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T172 | 594-600 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
T173 | 609-611 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T174 | 609-611 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T175 | 634-639 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T176 | 677-682 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T137 | 165-175 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T138 | 165-170 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T139 | 171-175 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T140 | 196-203 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T141 | 215-217 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T142 | 609-611 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T56 | 228-232 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
T57 | 256-261 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T58 | 559-563 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
T59 | 634-639 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T60 | 640-650 | http://purl.obolibrary.org/obo/IDO_0000498 | denotes | inoculated |
T61 | 677-682 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T62 | 683-693 | http://purl.obolibrary.org/obo/IDO_0000498 | denotes | inoculated |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T94 | 165-175 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T95 | 196-203 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T121 | 0-8 | Species | denotes | SARS-CoV | NCBItxid:694009 |
T122 | 13-22 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T123 | 530-535 | Species | denotes | human | NCBItxid:9606 |
T124 | 656-662 | Species | denotes | SARS-2 | NCBItxid:2697049 |
T125 | 699-703 | Species | denotes | SARS | NCBItxid:694009 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T117 | 0-362 | Sentence | denotes | SARS-CoV and SARS-CoV2 share absolutely the same cleavage junctions, almost the same sequence (96%) of their main protease, a high degree (76%) of similarity in the amino acid sequence of their S protein, a similar S2′ cleavage site, a similar spectrum of cells they can enter, and the similarity of the most residues essential for binding ACE2 [16], [17], [18]. |
T118 | 363-448 | Sentence | denotes | Also, both of them utilize the same domain of S1B to interact with the ACE2 receptor. |
T119 | 449-511 | Sentence | denotes | However, they differ in proteolytic processing to some degree. |
T120 | 512-706 | Sentence | denotes | Study [16] of the human embryonic kidney (HEK) cell line, 293 T, has shown that a signal for the S2 subunit is present in cells inoculated with SARS-2-S, but not in cells inoculated with SARS-S. |
LitCovid-sample-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T8 | 546-552 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
460 | 194-195 | Gene | denotes | S | Gene:43740568 |
456 | 340-344 | Gene | denotes | ACE2 | Gene:59272 |
457 | 434-438 | Gene | denotes | ACE2 | Gene:59272 |
463 | 530-535 | Species | denotes | human | Tax:9606 |
465 | 536-552 | Disease | denotes | embryonic kidney | MESH:D007674 |
466 | 554-557 | CellLine | denotes | HEK | CVCL:M624 |
467 | 570-575 | CellLine | denotes | 293 T | CVCL:0063 |
464 | 656-662 | Species | denotes | SARS-2 | Tax:2697049 |
459 | 663-664 | Gene | denotes | S | Gene:43740568 |
458 | 704-705 | Gene | denotes | S | Gene:43740568 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T1647 | 109-122 | Protein | denotes | main protease | https://www.uniprot.org/uniprot/Q80E51|https://www.uniprot.org/uniprot/Q80BV8|https://www.uniprot.org/uniprot/Q80BV7|https://www.uniprot.org/uniprot/Q808C0|https://www.uniprot.org/uniprot/Q7T697|https://www.uniprot.org/uniprot/Q6WGN0|https://www.uniprot.org/uniprot/P59641|https://www.uniprot.org/uniprot/P0DTD1|https://www.uniprot.org/uniprot/P0DTC1|https://www.uniprot.org/uniprot/P0C6X7|https://www.uniprot.org/uniprot/P0C6U8 |
T1658 | 194-203 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
T1691 | 409-412 | Protein | denotes | S1B | https://www.uniprot.org/uniprot/P47835 |
T1692 | 536-545 | Protein | denotes | embryonic | https://www.uniprot.org/uniprot/P02301 |
T1693 | 554-557 | Protein | denotes | HEK | https://www.uniprot.org/uniprot/Q9H2V4|https://www.uniprot.org/uniprot/Q9H2V3|https://www.uniprot.org/uniprot/P29320 |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T27640 | 0-8 | NN | denotes | SARS-CoV |
T74776 | 9-12 | CC | denotes | and |
T21368 | 13-22 | NN | denotes | SARS-CoV2 |
T82506 | 23-28 | NN | denotes | share |
T68425 | 29-39 | RB | denotes | absolutely |
T18098 | 40-43 | DT | denotes | the |
T56482 | 44-48 | JJ | denotes | same |
T5709 | 49-57 | NN | denotes | cleavage |
T53777 | 58-67 | NNS | denotes | junctions |
T48942 | 67-68 | -COMMA- | denotes | , |
T23620 | 69-75 | RB | denotes | almost |
T31417 | 76-79 | DT | denotes | the |
T14679 | 80-84 | JJ | denotes | same |
T16845 | 85-93 | NN | denotes | sequence |
T94095 | 94-95 | -LRB- | denotes | ( |
T72721 | 95-97 | CD | denotes | 96 |
T51290 | 97-98 | NN | denotes | % |
T3648 | 98-99 | -RRB- | denotes | ) |
T81238 | 100-102 | IN | denotes | of |
T80974 | 103-108 | PRP-DOLLAR- | denotes | their |
T24041 | 109-113 | JJ | denotes | main |
T97737 | 114-122 | NN | denotes | protease |
T89215 | 122-123 | -COMMA- | denotes | , |
T68838 | 124-125 | DT | denotes | a |
T10566 | 126-130 | JJ | denotes | high |
T25132 | 131-137 | NN | denotes | degree |
T56803 | 138-139 | -LRB- | denotes | ( |
T85670 | 139-141 | CD | denotes | 76 |
T72732 | 141-142 | NN | denotes | % |
T51047 | 142-143 | -RRB- | denotes | ) |
T87365 | 144-146 | IN | denotes | of |
T31118 | 147-157 | NN | denotes | similarity |
T29516 | 158-160 | IN | denotes | in |
T55756 | 161-164 | DT | denotes | the |
T19117 | 165-170 | JJ | denotes | amino |
T38328 | 171-175 | NN | denotes | acid |
T71701 | 176-184 | NN | denotes | sequence |
T52612 | 185-187 | IN | denotes | of |
T55072 | 188-193 | PRP-DOLLAR- | denotes | their |
T61270 | 194-195 | NN | denotes | S |
T71641 | 196-203 | NN | denotes | protein |
T35396 | 203-204 | -COMMA- | denotes | , |
T5992 | 205-206 | DT | denotes | a |
T7278 | 207-214 | JJ | denotes | similar |
T86199 | 215-218 | NN | denotes | S2′ |
T47005 | 219-227 | NN | denotes | cleavage |
T82402 | 228-232 | NN | denotes | site |
T47763 | 232-233 | -COMMA- | denotes | , |
T84821 | 234-235 | DT | denotes | a |
T82586 | 236-243 | JJ | denotes | similar |
T33761 | 244-252 | NN | denotes | spectrum |
T77477 | 253-255 | IN | denotes | of |
T52803 | 256-261 | NNS | denotes | cells |
T10303 | 262-266 | PRP | denotes | they |
T7764 | 267-270 | MD | denotes | can |
T28508 | 271-276 | VB | denotes | enter |
T62400 | 276-277 | -COMMA- | denotes | , |
T63048 | 278-281 | CC | denotes | and |
T36374 | 282-285 | DT | denotes | the |
T14538 | 286-296 | NN | denotes | similarity |
T20437 | 297-299 | IN | denotes | of |
T68062 | 300-303 | DT | denotes | the |
T38190 | 304-308 | JJS | denotes | most |
T74458 | 309-317 | NNS | denotes | residues |
T87029 | 318-327 | JJ | denotes | essential |
T85323 | 328-331 | IN | denotes | for |
T99917 | 332-339 | VBG | denotes | binding |
T21537 | 340-344 | NN | denotes | ACE2 |
T6014 | 345-346 | -LRB- | denotes | [ |
T41035 | 346-348 | CD | denotes | 16 |
T8340 | 348-349 | -RRB- | denotes | ] |
T30067 | 349-350 | -COMMA- | denotes | , |
T62375 | 351-352 | -LRB- | denotes | [ |
T93474 | 352-354 | CD | denotes | 17 |
T91627 | 354-355 | -RRB- | denotes | ] |
T61038 | 355-356 | -COMMA- | denotes | , |
T23050 | 357-358 | -LRB- | denotes | [ |
T2153 | 358-360 | CD | denotes | 18 |
T12115 | 360-361 | -RRB- | denotes | ] |
T92800 | 363-367 | RB | denotes | Also |
T47629 | 367-368 | -COMMA- | denotes | , |
T61968 | 369-373 | DT | denotes | both |
T81337 | 374-376 | IN | denotes | of |
T3352 | 377-381 | PRP | denotes | them |
T94564 | 382-389 | VBP | denotes | utilize |
T79549 | 390-393 | DT | denotes | the |
T81034 | 394-398 | JJ | denotes | same |
T66440 | 399-405 | NN | denotes | domain |
T64350 | 406-408 | IN | denotes | of |
T84214 | 409-412 | NN | denotes | S1B |
T9559 | 413-415 | TO | denotes | to |
T41916 | 416-424 | VB | denotes | interact |
T92667 | 425-429 | IN | denotes | with |
T6335 | 430-433 | DT | denotes | the |
T19773 | 434-438 | NN | denotes | ACE2 |
T62479 | 439-447 | NN | denotes | receptor |
T90671 | 449-456 | RB | denotes | However |
T39710 | 456-457 | -COMMA- | denotes | , |
T81474 | 458-462 | PRP | denotes | they |
T56686 | 463-469 | VBP | denotes | differ |
T68640 | 470-472 | IN | denotes | in |
T87109 | 473-484 | JJ | denotes | proteolytic |
T98211 | 485-495 | NN | denotes | processing |
T71821 | 496-498 | TO | denotes | to |
T76662 | 499-503 | DT | denotes | some |
T50781 | 504-510 | NN | denotes | degree |
T10243 | 512-517 | NN | denotes | Study |
T47759 | 518-519 | -LRB- | denotes | [ |
T98110 | 519-521 | CD | denotes | 16 |
T87807 | 521-522 | -RRB- | denotes | ] |
T21860 | 523-525 | IN | denotes | of |
T41284 | 526-529 | DT | denotes | the |
T98832 | 530-535 | JJ | denotes | human |
T59673 | 536-545 | JJ | denotes | embryonic |
T56471 | 546-552 | NN | denotes | kidney |
T99239 | 553-554 | -LRB- | denotes | ( |
T14503 | 554-557 | NN | denotes | HEK |
T28717 | 557-558 | -RRB- | denotes | ) |
T37299 | 559-563 | NN | denotes | cell |
T7184 | 564-568 | NN | denotes | line |
T85187 | 568-569 | -COMMA- | denotes | , |
T92189 | 570-575 | NN | denotes | 293 T |
T15543 | 575-576 | -COMMA- | denotes | , |
T94164 | 577-580 | VBZ | denotes | has |
T43431 | 581-586 | VBN | denotes | shown |
T43613 | 587-591 | IN | denotes | that |
T18285 | 592-593 | DT | denotes | a |
T61673 | 594-600 | NN | denotes | signal |
T89124 | 601-604 | IN | denotes | for |
T39220 | 605-608 | DT | denotes | the |
T95765 | 609-611 | NN | denotes | S2 |
T75829 | 612-619 | NN | denotes | subunit |
T59345 | 620-622 | VBZ | denotes | is |
T37161 | 623-630 | JJ | denotes | present |
T63565 | 631-633 | IN | denotes | in |
T66184 | 634-639 | NNS | denotes | cells |
T20519 | 640-650 | VBN | denotes | inoculated |
T83162 | 651-655 | IN | denotes | with |
T31219 | 656-664 | NN | denotes | SARS-2-S |
T44086 | 664-665 | -COMMA- | denotes | , |
T88144 | 666-669 | CC | denotes | but |
T98702 | 670-673 | RB | denotes | not |
T7566 | 674-676 | IN | denotes | in |
T55250 | 677-682 | NNS | denotes | cells |
T72973 | 683-693 | VBN | denotes | inoculated |
T20341 | 694-698 | IN | denotes | with |
T62455 | 699-705 | NN | denotes | SARS-S |
R28577 | T7184 | T98832 | arg1Of | line,human |
R27054 | T7184 | T59673 | arg1Of | line,embryonic |
R83092 | T7184 | T56471 | arg1Of | line,kidney |
R80643 | T7184 | T99239 | arg1Of | line,( |
R22992 | T14503 | T99239 | arg2Of | HEK,( |
R62931 | T28717 | T99239 | arg3Of | ),( |
R42203 | T7184 | T37299 | arg1Of | line,cell |
R72776 | T7184 | T85187 | arg1Of | line,"," |
R17912 | T92189 | T85187 | arg2Of | 293 T,"," |
R63165 | T43431 | T15543 | arg1Of | shown,"," |
R37777 | T10243 | T94164 | arg1Of | Study,has |
R76746 | T43431 | T94164 | arg2Of | shown,has |
R58146 | T10243 | T43431 | arg1Of | Study,shown |
R72554 | T59345 | T43431 | arg2Of | is,shown |
R7678 | T59345 | T43613 | arg1Of | is,that |
R40491 | T61673 | T18285 | arg1Of | signal,a |
R59867 | T61673 | T89124 | arg1Of | signal,for |
R93633 | T75829 | T89124 | arg2Of | subunit,for |
R19499 | T27640 | T74776 | arg1Of | SARS-CoV,and |
R79812 | T21368 | T74776 | arg2Of | SARS-CoV2,and |
R26368 | T74776 | T82506 | arg1Of | and,share |
R29995 | T53777 | T82506 | arg2Of | junctions,share |
R25449 | T53777 | T68425 | arg1Of | junctions,absolutely |
R92888 | T53777 | T18098 | arg1Of | junctions,the |
R64712 | T53777 | T56482 | arg1Of | junctions,same |
R80207 | T53777 | T5709 | arg1Of | junctions,cleavage |
R71489 | T53777 | T48942 | arg1Of | junctions,"," |
R46099 | T16845 | T48942 | arg2Of | sequence,"," |
R57449 | T16845 | T23620 | arg1Of | sequence,almost |
R93097 | T16845 | T31417 | arg1Of | sequence,the |
R60648 | T16845 | T14679 | arg1Of | sequence,same |
R3648 | T16845 | T94095 | arg1Of | sequence,( |
R79215 | T51290 | T94095 | arg2Of | %,( |
R15037 | T3648 | T94095 | arg3Of | ),( |
R62417 | T51290 | T72721 | arg1Of | %,96 |
R92776 | T82506 | T81238 | arg1Of | share,of |
R81984 | T97737 | T81238 | arg2Of | protease,of |
R32244 | T97737 | T80974 | arg1Of | protease,their |
R86147 | T97737 | T24041 | arg1Of | protease,main |
R38683 | T97737 | T89215 | arg1Of | protease,"," |
R87714 | T25132 | T89215 | arg2Of | degree,"," |
R95545 | T25132 | T68838 | arg1Of | degree,a |
R19622 | T25132 | T10566 | arg1Of | degree,high |
R72431 | T25132 | T56803 | arg1Of | degree,( |
R44226 | T72732 | T56803 | arg2Of | %,( |
R41044 | T51047 | T56803 | arg3Of | ),( |
R16754 | T72732 | T85670 | arg1Of | %,76 |
R21351 | T25132 | T87365 | arg1Of | degree,of |
R85039 | T31118 | T87365 | arg2Of | similarity,of |
R13660 | T25132 | T29516 | arg1Of | degree,in |
R9808 | T71701 | T29516 | arg2Of | sequence,in |
R60303 | T71701 | T55756 | arg1Of | sequence,the |
R56074 | T71701 | T19117 | arg1Of | sequence,amino |
R10836 | T71701 | T38328 | arg1Of | sequence,acid |
R31772 | T71701 | T52612 | arg1Of | sequence,of |
R53920 | T71641 | T52612 | arg2Of | protein,of |
R95893 | T71641 | T55072 | arg1Of | protein,their |
R26551 | T71641 | T61270 | arg1Of | protein,S |
R93335 | T97737 | T35396 | arg1Of | protease,"," |
R50792 | T63048 | T35396 | arg2Of | and,"," |
R69371 | T82402 | T5992 | arg1Of | site,a |
R8336 | T82402 | T7278 | arg1Of | site,similar |
R22174 | T82402 | T86199 | arg1Of | site,S2′ |
R58251 | T82402 | T47005 | arg1Of | site,cleavage |
R76790 | T82402 | T47763 | arg1Of | site,"," |
R89371 | T33761 | T47763 | arg2Of | spectrum,"," |
R42990 | T33761 | T84821 | arg1Of | spectrum,a |
R16681 | T33761 | T82586 | arg1Of | spectrum,similar |
R12595 | T33761 | T77477 | arg1Of | spectrum,of |
R83284 | T52803 | T77477 | arg2Of | cells,of |
R28065 | T10303 | T7764 | arg1Of | they,can |
R86622 | T28508 | T7764 | arg2Of | enter,can |
R32128 | T10303 | T28508 | arg1Of | they,enter |
R39883 | T52803 | T28508 | arg2Of | cells,enter |
R20426 | T63048 | T62400 | arg1Of | and,"," |
R47510 | T82402 | T63048 | arg1Of | site,and |
R49926 | T14538 | T63048 | arg2Of | similarity,and |
R88041 | T14538 | T36374 | arg1Of | similarity,the |
R27614 | T14538 | T20437 | arg1Of | similarity,of |
R47891 | T74458 | T20437 | arg2Of | residues,of |
R60630 | T74458 | T68062 | arg1Of | residues,the |
R47010 | T74458 | T38190 | arg1Of | residues,most |
R50036 | T74458 | T87029 | arg1Of | residues,essential |
R9047 | T87029 | T85323 | arg1Of | essential,for |
R32534 | T99917 | T85323 | arg2Of | binding,for |
R60201 | T21537 | T99917 | arg2Of | ACE2,binding |
R23772 | T21537 | T6014 | arg1Of | ACE2,[ |
R71679 | T41035 | T6014 | arg2Of | 16,[ |
R9958 | T8340 | T6014 | arg3Of | ],[ |
R10122 | T97737 | T30067 | arg1Of | protease,"," |
R98234 | T82506 | T62375 | arg1Of | share,[ |
R42646 | T93474 | T62375 | arg2Of | 17,[ |
R68299 | T91627 | T62375 | arg3Of | ],[ |
R94590 | T82506 | T61038 | arg1Of | share,"," |
R18775 | T82506 | T23050 | arg1Of | share,[ |
R47881 | T2153 | T23050 | arg2Of | 18,[ |
R86136 | T12115 | T23050 | arg3Of | ],[ |
R27747 | T94564 | T92800 | arg1Of | utilize,Also |
R19625 | T94564 | T47629 | arg1Of | utilize,"," |
R21542 | T61968 | T81337 | arg1Of | both,of |
R11531 | T3352 | T81337 | arg2Of | them,of |
R28970 | T61968 | T94564 | arg1Of | both,utilize |
R80079 | T66440 | T94564 | arg2Of | domain,utilize |
R51607 | T41916 | T94564 | arg3Of | interact,utilize |
R62774 | T66440 | T79549 | arg1Of | domain,the |
R86253 | T66440 | T81034 | arg1Of | domain,same |
R85149 | T66440 | T64350 | arg1Of | domain,of |
R4625 | T84214 | T64350 | arg2Of | S1B,of |
R17724 | T41916 | T9559 | arg1Of | interact,to |
R47877 | T41916 | T92667 | arg1Of | interact,with |
R74735 | T62479 | T92667 | arg2Of | receptor,with |
R86134 | T62479 | T6335 | arg1Of | receptor,the |
R33270 | T62479 | T19773 | arg1Of | receptor,ACE2 |
R63519 | T56686 | T90671 | arg1Of | differ,However |
R90411 | T56686 | T39710 | arg1Of | differ,"," |
R62759 | T81474 | T56686 | arg1Of | they,differ |
R48042 | T56686 | T68640 | arg1Of | differ,in |
R96381 | T98211 | T68640 | arg2Of | processing,in |
R16643 | T98211 | T87109 | arg1Of | processing,proteolytic |
R11446 | T98211 | T71821 | arg1Of | processing,to |
R19479 | T50781 | T71821 | arg2Of | degree,to |
R8489 | T50781 | T76662 | arg1Of | degree,some |
R99384 | T10243 | T47759 | arg1Of | Study,[ |
R1825 | T98110 | T47759 | arg2Of | 16,[ |
R66257 | T87807 | T47759 | arg3Of | ],[ |
R58356 | T10243 | T21860 | arg1Of | Study,of |
R23338 | T7184 | T21860 | arg2Of | line,of |
R95003 | T7184 | T41284 | arg1Of | line,the |
R23414 | T75829 | T39220 | arg1Of | subunit,the |
R62130 | T75829 | T95765 | arg1Of | subunit,S2 |
R31098 | T61673 | T59345 | arg1Of | signal,is |
R3726 | T37161 | T59345 | arg2Of | present,is |
R76876 | T61673 | T37161 | arg1Of | signal,present |
R63867 | T37161 | T63565 | arg1Of | present,in |
R2570 | T66184 | T63565 | arg2Of | cells,in |
R48403 | T66184 | T20519 | arg2Of | cells,inoculated |
R97799 | T20519 | T83162 | arg1Of | inoculated,with |
R20386 | T31219 | T83162 | arg2Of | SARS-2-S,with |
R51176 | T88144 | T44086 | arg1Of | but,"," |
R17963 | T83162 | T88144 | arg1Of | with,but |
R27005 | T7566 | T88144 | arg2Of | in,but |
R9329 | T7566 | T98702 | arg1Of | in,not |
R49359 | T20519 | T7566 | arg1Of | inoculated,in |
R90100 | T55250 | T7566 | arg2Of | cells,in |
R89636 | T55250 | T72973 | arg2Of | cells,inoculated |
R14196 | T72973 | T20341 | arg1Of | inoculated,with |
R48113 | T62455 | T20341 | arg2Of | SARS-S,with |
LitCovid-sample-PD-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 546-552 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T106 | 165-175 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T107 | 196-203 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T108 | 256-261 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T109 | 546-552 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T110 | 559-563 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T111 | 634-639 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T112 | 677-682 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T86 | 0-8 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T87 | 13-22 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T88 | 656-660 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T89 | 699-703 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T117 | 0-362 | Sentence | denotes | SARS-CoV and SARS-CoV2 share absolutely the same cleavage junctions, almost the same sequence (96%) of their main protease, a high degree (76%) of similarity in the amino acid sequence of their S protein, a similar S2′ cleavage site, a similar spectrum of cells they can enter, and the similarity of the most residues essential for binding ACE2 [16], [17], [18]. |
T118 | 363-448 | Sentence | denotes | Also, both of them utilize the same domain of S1B to interact with the ACE2 receptor. |
T119 | 449-511 | Sentence | denotes | However, they differ in proteolytic processing to some degree. |
T120 | 512-706 | Sentence | denotes | Study [16] of the human embryonic kidney (HEK) cell line, 293 T, has shown that a signal for the S2 subunit is present in cells inoculated with SARS-2-S, but not in cells inoculated with SARS-S. |