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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"5","span":{"begin":0,"end":4},"obj":"Gene"},{"id":"6","span":{"begin":46,"end":56},"obj":"Species"},{"id":"7","span":{"begin":58,"end":70},"obj":"Disease"},{"id":"8","span":{"begin":72,"end":91},"obj":"Disease"},{"id":"9","span":{"begin":97,"end":105},"obj":"Disease"},{"id":"39","span":{"begin":702,"end":735},"obj":"Gene"},{"id":"40","span":{"begin":737,"end":741},"obj":"Gene"},{"id":"41","span":{"begin":974,"end":978},"obj":"Gene"},{"id":"42","span":{"begin":990,"end":994},"obj":"Gene"},{"id":"46","span":{"begin":668,"end":673},"obj":"Gene"},{"id":"47","span":{"begin":136,"end":183},"obj":"Species"},{"id":"48","span":{"begin":185,"end":195},"obj":"Species"},{"id":"49","span":{"begin":221,"end":227},"obj":"Species"},{"id":"50","span":{"begin":356,"end":364},"obj":"Species"},{"id":"51","span":{"begin":447,"end":454},"obj":"Species"},{"id":"52","span":{"begin":535,"end":541},"obj":"Species"},{"id":"53","span":{"begin":562,"end":574},"obj":"Species"},{"id":"54","span":{"begin":657,"end":667},"obj":"Species"},{"id":"55","span":{"begin":696,"end":701},"obj":"Species"},{"id":"56","span":{"begin":899,"end":905},"obj":"Species"},{"id":"57","span":{"begin":1036,"end":1041},"obj":"Species"},{"id":"60","span":{"begin":879,"end":890},"obj":"Chemical"},{"id":"61","span":{"begin":292,"end":300},"obj":"Disease"},{"id":"62","span":{"begin":333,"end":339},"obj":"Disease"}],"attributes":[{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"Gene:59272"},{"id":"A6","pred":"tao:has_database_id","subj":"6","obj":"Tax:2697049"},{"id":"A7","pred":"tao:has_database_id","subj":"7","obj":"MESH:D006973"},{"id":"A8","pred":"tao:has_database_id","subj":"8","obj":"MESH:D009102"},{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"MESH:C000657245"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"Gene:59272"},{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"Gene:59272"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"Gene:59272"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"Gene:59272"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Gene:43740568"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Tax:2697049"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Tax:2697049"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Tax:9606"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Tax:694009"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"Tax:9606"},{"id":"A52","pred":"tao:has_database_id","subj":"52","obj":"Tax:9606"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Tax:9606"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:2697049"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Tax:9606"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"Tax:9606"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"Tax:9606"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D000450"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:C000657245"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":78,"end":83},"obj":"Body_part"},{"id":"T2","span":{"begin":674,"end":681},"obj":"Body_part"},{"id":"T3","span":{"begin":790,"end":805},"obj":"Body_part"},{"id":"T4","span":{"begin":806,"end":822},"obj":"Body_part"},{"id":"T5","span":{"begin":817,"end":822},"obj":"Body_part"},{"id":"T6","span":{"begin":833,"end":840},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma67498"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma17530"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":78,"end":83},"obj":"Body_part"},{"id":"T2","span":{"begin":801,"end":805},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":46,"end":54},"obj":"Disease"},{"id":"T2","span":{"begin":46,"end":50},"obj":"Disease"},{"id":"T3","span":{"begin":58,"end":70},"obj":"Disease"},{"id":"T4","span":{"begin":72,"end":91},"obj":"Disease"},{"id":"T5","span":{"begin":97,"end":105},"obj":"Disease"},{"id":"T6","span":{"begin":136,"end":183},"obj":"Disease"},{"id":"T7","span":{"begin":136,"end":169},"obj":"Disease"},{"id":"T8","span":{"begin":185,"end":193},"obj":"Disease"},{"id":"T9","span":{"begin":185,"end":189},"obj":"Disease"},{"id":"T10","span":{"begin":292,"end":300},"obj":"Disease"},{"id":"T11","span":{"begin":356,"end":364},"obj":"Disease"},{"id":"T12","span":{"begin":356,"end":360},"obj":"Disease"},{"id":"T13","span":{"begin":657,"end":665},"obj":"Disease"},{"id":"T14","span":{"begin":657,"end":661},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0043726"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":78,"end":83},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T2","span":{"begin":198,"end":201},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T3","span":{"begin":249,"end":252},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T4","span":{"begin":354,"end":355},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T5","span":{"begin":370,"end":375},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T6","span":{"begin":405,"end":406},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T7","span":{"begin":456,"end":457},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T8","span":{"begin":535,"end":541},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T9","span":{"begin":562,"end":574},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T10","span":{"begin":578,"end":579},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T11","span":{"begin":611,"end":616},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T12","span":{"begin":696,"end":701},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T13","span":{"begin":761,"end":762},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":801,"end":822},"obj":"http://purl.obolibrary.org/obo/CL_0000082"},{"id":"T15","span":{"begin":899,"end":905},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T16","span":{"begin":1036,"end":1041},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":674,"end":681},"obj":"Chemical"},{"id":"T2","span":{"begin":702,"end":713},"obj":"Chemical"},{"id":"T3","span":{"begin":749,"end":757},"obj":"Chemical"},{"id":"T4","span":{"begin":867,"end":878},"obj":"Chemical"},{"id":"T5","span":{"begin":879,"end":890},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_27584"},{"id":"A6","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_30834"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":58,"end":70},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0000822"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":27},"obj":"Sentence"},{"id":"T2","span":{"begin":28,"end":121},"obj":"Sentence"},{"id":"T3","span":{"begin":123,"end":131},"obj":"Sentence"},{"id":"T4","span":{"begin":132,"end":340},"obj":"Sentence"},{"id":"T5","span":{"begin":341,"end":625},"obj":"Sentence"},{"id":"T6","span":{"begin":626,"end":743},"obj":"Sentence"},{"id":"T7","span":{"begin":744,"end":898},"obj":"Sentence"},{"id":"T8","span":{"begin":899,"end":979},"obj":"Sentence"},{"id":"T9","span":{"begin":980,"end":1054},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome\n\nAbstract\nThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in Chinese people in December 2019 and has currently spread worldwide causing the COVID-19 pandemic with more than 150,000 deaths. In order for a SARS-CoV like virus circulating in wild life for a very long time to infect the index case-patient, a number of conditions must be met, foremost among which is the encounter with humans and the presence in homo sapiens of a cellular receptor allowing the virus to bind. Recently it was shown that the SARS-CoV-2 spike protein, binds to the human angiotensin I converting enzyme 2 (ACE2). This molecule is a peptidase expressed at the surface of lung epithelial cells and other tissues, that regulates the renin-angiotensin-aldosterone system. Humans are not equal with respect to the expression levels of the cellular ACE2. Moreover, ACE2 polymorphisms were recently described in human populations. Here we review "}