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PMC:7200337 / 90125-91400 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-15860669-46575411 848-852 15860669 denotes 2005
32505227-32303591-46575412 870-874 32303591 denotes 2020
32505227-15919935-46575413 1132-1136 15919935 denotes 2005
32505227-17052299-46575414 1152-1156 17052299 denotes 2006
32505227-15888207-46575415 1212-1216 15888207 denotes 2005
32505227-15030519-46575416 1231-1235 15030519 denotes 2004
T3486 848-852 15860669 denotes 2005
T86573 870-874 32303591 denotes 2020
T99556 1132-1136 15919935 denotes 2005
T42792 1152-1156 17052299 denotes 2006
T45143 1212-1216 15888207 denotes 2005
T73456 1231-1235 15030519 denotes 2004

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T708 86-94 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T709 224-229 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T710 246-249 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T711 428-437 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T712 453-457 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T713 463-473 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T714 650-654 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T715 675-684 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T716 689-700 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T717 741-750 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T718 763-771 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T719 1025-1034 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T720 1036-1047 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T721 1072-1080 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T512 113-121 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T513 186-197 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T514 287-295 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T515 313-321 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T516 559-567 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T517 754-762 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T518 930-940 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T519 952-960 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T946 218-221 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T947 222-229 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T948 453-457 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T949 517-518 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T950 650-654 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T951 675-684 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T952 1025-1034 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T953 1060-1061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T954 1109-1115 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T279 136-141 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T280 243-245 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T281 254-256 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T283 453-455 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T52 86-100 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T53 186-197 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T54 763-777 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2960 218-221 Gene denotes CD4 Gene:920
2961 243-249 Gene denotes GM-CSF Gene:1437
2962 254-258 Gene denotes IL-6 Gene:3569
2963 439-444 Gene denotes TNF-α Gene:7124
2964 446-451 Gene denotes IFN-ɣ Gene:3458
2965 453-457 Gene denotes IL-2 Gene:3558
2966 475-479 Gene denotes CCL2 Gene:6347
2967 481-485 Gene denotes CCL3 Gene:6348
2968 487-491 Gene denotes CCL4 Gene:6351
2969 542-547 Gene denotes TH1/2 Gene:51497
2970 79-81 Gene denotes to Gene:6999
2971 27-29 Gene denotes to Gene:6999
2972 122-130 Species denotes patients Tax:9606
2973 296-304 Species denotes patients Tax:9606
2974 322-330 Species denotes patients Tax:9606
2975 914-929 Species denotes betacoronavirus Tax:694002
2976 952-960 Species denotes SARS-CoV Tax:694009
2977 967-975 Species denotes MERS-CoV Tax:1335626
2978 1109-1115 Species denotes humans Tax:9606
2979 113-121 Disease denotes COVID-19 MESH:C000657245
2980 186-197 Disease denotes lymphopenia MESH:D008231
2981 287-295 Disease denotes COVID-19 MESH:C000657245
2982 313-321 Disease denotes COVID-19 MESH:C000657245
2983 559-567 Disease denotes COVID-19 MESH:C000657245
2984 754-762 Disease denotes COVID-19 MESH:C000657245
2985 930-940 Disease denotes infections MESH:D007239

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T515 0-131 Sentence denotes Several studies have begun to report the cellular programs that may contribute to the cytokine storm detected in COVID-19 patients.
T516 132-386 Sentence denotes One group reported that in the context of generalized lymphopenia, certain subsets of CD4 T cells that express GM-CSF and IL-6 are more abundant in severe COVID-19 patients than in COVID-19 patients who do not require intensive care (Zhou et al., 2020b).
T517 387-625 Sentence denotes Reports that other major proinflammatory cytokines (TNF-α, IFN-ɣ, IL-2) and chemokines (CCL2, CCL3, CCL4) are elevated underscore a potentially pathogenic TH1/2 program in COVID-19 (Diao et al., 2020, Giamarellos-Bourboulis et al., 2020).
T518 626-896 Sentence denotes Histological and single-cell analyses identified monocytes and macrophages as other potent sources of inflammatory cytokines in COVID-19 cytokine storm (Chen et al., 2020h, Giamarellos-Bourboulis et al., 2020, Law et al., 2005, Moore and June, 2020, Zhou et al., 2020b).
T519 897-1275 Sentence denotes Studies of other betacoronavirus infections, including SARS-CoV-1 and MERS-CoV, have also identified similar hyperactivation of monocytes, macrophages, and DCs as a driver of cytokine-mediated immunopathology in humans (Cheung et al., 2005, Chien et al., 2006, Huang et al., 2020c, Konig et al., 2020, Wang et al., 2005, Wong et al., 2004, Xu et al., 2020b, Zhou et al., 2020b).