PMC:7200337 / 89533-90124 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7200337","sourcedb":"PMC","sourceid":"7200337","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7200337","text":"Hyperinflammatory responses and elevated levels of inflammatory cytokines, including IL-6, -8, and -10, have been shown to correlate with COVID-19 severity (Chen et al., 2020h, Diao et al., 2020, Gong et al., 2020, Moore and June, 2020, Wan et al., 2020a, Xu et al., 2020b). The drivers of this cytokine storm remain to be established, but they are likely triggered initially by a combination of viral PAMPs and host danger signals. The heterogeneous response between patients suggests other factors are involved, possibly including the SARS-CoV-2 receptor, ACE2 (Hirano and Murakami, 2020).","tracks":[{"project":"2_test","denotations":[{"id":"32505227-32303591-46575410","span":{"begin":231,"end":235},"obj":"32303591"},{"id":"T3033","span":{"begin":231,"end":235},"obj":"32303591"}],"attributes":[{"subj":"32505227-32303591-46575410","pred":"source","obj":"2_test"},{"subj":"T3033","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T706","span":{"begin":64,"end":73},"obj":"Body_part"},{"id":"T707","span":{"begin":295,"end":303},"obj":"Body_part"}],"attributes":[{"id":"A706","pred":"fma_id","subj":"T706","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A707","pred":"fma_id","subj":"T707","obj":"http://purl.org/sig/ont/fma/fma84050"},{"subj":"T706","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T707","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T510","span":{"begin":138,"end":146},"obj":"Disease"},{"id":"T511","span":{"begin":537,"end":545},"obj":"Disease"}],"attributes":[{"id":"A510","pred":"mondo_id","subj":"T510","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A511","pred":"mondo_id","subj":"T511","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T510","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T511","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T944","span":{"begin":379,"end":380},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T945","span":{"begin":424,"end":431},"obj":"http://purl.obolibrary.org/obo/SO_0000418"}],"attributes":[{"subj":"T944","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T945","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T277","span":{"begin":85,"end":87},"obj":"Chemical"}],"attributes":[{"id":"A277","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A278","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"subj":"T277","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T51","span":{"begin":295,"end":309},"obj":"Phenotype"}],"attributes":[{"id":"A51","pred":"hp_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"2927","span":{"begin":85,"end":102},"obj":"Gene"},{"id":"2928","span":{"begin":558,"end":562},"obj":"Gene"},{"id":"2929","span":{"begin":317,"end":319},"obj":"Gene"},{"id":"2930","span":{"begin":120,"end":122},"obj":"Gene"},{"id":"2931","span":{"begin":468,"end":476},"obj":"Species"},{"id":"2932","span":{"begin":537,"end":547},"obj":"Species"},{"id":"2933","span":{"begin":138,"end":146},"obj":"Disease"}],"attributes":[{"id":"A2927","pred":"tao:has_database_id","subj":"2927","obj":"Gene:3569"},{"id":"A2928","pred":"tao:has_database_id","subj":"2928","obj":"Gene:59272"},{"id":"A2929","pred":"tao:has_database_id","subj":"2929","obj":"Gene:6999"},{"id":"A2930","pred":"tao:has_database_id","subj":"2930","obj":"Gene:6999"},{"id":"A2931","pred":"tao:has_database_id","subj":"2931","obj":"Tax:9606"},{"id":"A2932","pred":"tao:has_database_id","subj":"2932","obj":"Tax:2697049"},{"id":"A2933","pred":"tao:has_database_id","subj":"2933","obj":"MESH:C000657245"},{"subj":"2927","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2928","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2929","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2930","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2931","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2932","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2933","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T512","span":{"begin":0,"end":274},"obj":"Sentence"},{"id":"T513","span":{"begin":275,"end":432},"obj":"Sentence"},{"id":"T514","span":{"begin":433,"end":591},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T512","pred":"source","obj":"LitCovid-sentences"},{"subj":"T513","pred":"source","obj":"LitCovid-sentences"},{"subj":"T514","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute 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