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PMC:7200337 / 51834-53171 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-16299724-46575353 199-203 16299724 denotes 2006
32505227-26497532-46575354 615-619 26497532 denotes 2015
32505227-24885320-46575355 985-989 24885320 denotes 2014
T99561 199-203 16299724 denotes 2006
T95047 615-619 26497532 denotes 2015
T7910 985-989 24885320 denotes 2014

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T515 236-244 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T516 314-322 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T517 428-431 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T518 502-507 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T519 522-533 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T520 538-547 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T521 593-598 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T522 687-690 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T523 719-723 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T524 765-774 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T525 779-790 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T526 798-802 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T527 836-841 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T528 934-942 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T529 951-962 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T530 1032-1040 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T54 719-723 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T55 798-802 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T56 836-841 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T326 39-47 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T327 346-349 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T328 633-641 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T329 713-730 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T331 724-730 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T332 732-735 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T333 868-876 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T334 901-910 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T335 914-922 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T336 992-995 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T337 1148-1151 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T338 1195-1203 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T339 1288-1296 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T641 211-214 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T642 264-271 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T643 413-418 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T644 452-457 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T645 473-475 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T646 502-507 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T647 538-547 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T648 573-583 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T649 593-598 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T650 622-623 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T651 653-668 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T652 719-723 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T653 719-723 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T654 765-774 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T655 798-802 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T656 798-802 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T657 928-933 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T658 934-942 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T659 1019-1020 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T660 1055-1056 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T28 713-730 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T29 732-735 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1702 557-559 Gene denotes to Gene:6999
1703 287-289 Gene denotes to Gene:6999
1704 255-257 Gene denotes to Gene:6999
1705 219-221 Gene denotes to Gene:6999
1706 154-156 Gene denotes to Gene:6999
1707 97-99 Gene denotes to Gene:6999
1708 39-47 Species denotes SARS-CoV Tax:694009
1709 136-144 Species denotes patients Tax:9606
1710 157-165 Species denotes patients Tax:9606
1711 653-668 Species denotes rhesus macaques Tax:9544
1712 868-876 Species denotes SARS-CoV Tax:694009
1713 879-887 Species denotes patients Tax:9606
1714 914-922 Species denotes SARS-CoV Tax:694009
1715 928-933 Species denotes human Tax:9606
1716 1057-1064 Species denotes patient Tax:9606
1717 1070-1078 Species denotes MERS-CoV Tax:1335626
1718 1174-1178 Species denotes rats Tax:10116
1719 1195-1205 Species denotes SARS-CoV-2 Tax:2697049
1720 1288-1298 Species denotes SARS-CoV-2 Tax:2697049
1721 633-652 Disease denotes SARS-CoV-1-infected MESH:C000657245
1722 713-730 Disease denotes acute lung injury MESH:D055371
1723 901-910 Disease denotes infection MESH:D007239

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T284 0-205 Sentence denotes This was also observed in the previous SARS-CoV-1 epidemic, where neutralizing titers were found to be significantly higher in deceased patients compared to patients who had recovered (Zhang et al., 2006).
T285 206-362 Sentence denotes This has led to concerns that antibody responses to these viruses may contribute to pulmonary pathology via antibody-dependent enhancement (ADE) (Figure 4).
T286 363-621 Sentence denotes This phenomenon is observed when non-neutralizing virus-specific IgG facilitate entry of virus particles into Fc-receptor (FcR) expressing cells, particularly macrophages and monocytes, leading to inflammatory activation of these cells (Taylor et al., 2015).
T287 622-822 Sentence denotes A study in SARS-CoV-1-infected rhesus macaques found that anti-S IgG contributed to severe acute lung injury (ALI) and massive accumulation of monocytes and macrophages in the lung (Liu et al., 2019).
T288 823-991 Sentence denotes Furthermore, serum containing anti-S Ig from SARS-CoV-1 patients enhanced the infection of SARS-CoV-1 in human monocyte-derived macrophages in vitro (Yip et al., 2014).
T289 992-1099 Sentence denotes ADE was also reported with a monoclonal antibody isolated from a patient with MERS-CoV (Wan et al., 2020c).
T290 1100-1337 Sentence denotes Somewhat reassuringly, there was no evidence of ADE mediated by sera from rats vaccinated with SARS-CoV-2 RBD in vitro (Quinlan et al., 2020) nor in macaques immunized with an inactivated SARS-CoV-2 vaccine candidate (Gao et al., 2020c).