PMC:7200337 / 21316-28807
Annnotations
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32505227-30142344-46575272 | 363-367 | 30142344 | denotes | 2018 |
| 32505227-26472762-46575274 | 1062-1066 | 26472762 | denotes | 2015 |
| 32505227-27670241-46575275 | 1086-1090 | 27670241 | denotes | 2017 |
| 32505227-29719539-46575276 | 1191-1195 | 29719539 | denotes | 2018 |
| 32505227-11905813-46575277 | 1937-1941 | 11905813 | denotes | 2001 |
| 32505227-17312110-46575278 | 1958-1962 | 17312110 | denotes | 2007 |
| 32505227-26919106-46575279 | 1983-1987 | 26919106 | denotes | 2016 |
| 32505227-22615821-46575280 | 2005-2009 | 22615821 | denotes | 2012 |
| 32505227-31316510-46575281 | 2723-2727 | 31316510 | denotes | 2019 |
| 32505227-19587043-46575283 | 3620-3624 | 19587043 | denotes | 2009 |
| 32505227-27670241-46575284 | 4100-4104 | 27670241 | denotes | 2017 |
| 32505227-30778167-46575285 | 4315-4319 | 30778167 | denotes | 2019 |
| 32505227-15080302-46575286 | 4474-4478 | 15080302 | denotes | 2004 |
| 32505227-9486650-46575289 | 4916-4920 | 9486650 | denotes | 1998 |
| 32505227-9034158-46575290 | 4937-4941 | 9034158 | denotes | 1997 |
| 32505227-29302013-46575291 | 5043-5047 | 29302013 | denotes | 2018 |
| 32505227-26251193-46575293 | 5742-5746 | 26251193 | denotes | 2015 |
| 32505227-19559672-46575295 | 6076-6080 | 19559672 | denotes | 2009 |
| 32505227-30524877-46575296 | 6139-6143 | 30524877 | denotes | 2017 |
| 32505227-26727464-46575297 | 6694-6698 | 26727464 | denotes | 2016 |
| 32505227-30770247-46575298 | 6716-6720 | 30770247 | denotes | 2019 |
| 32505227-21946417-46575299 | 6927-6931 | 21946417 | denotes | 2011 |
| 32505227-21623379-46575300 | 7088-7092 | 21623379 | denotes | 2011 |
| 32505227-30414858-46575301 | 7259-7263 | 30414858 | denotes | 2019 |
| T28986 | 363-367 | 30142344 | denotes | 2018 |
| T72451 | 1062-1066 | 26472762 | denotes | 2015 |
| T73641 | 1086-1090 | 27670241 | denotes | 2017 |
| T99238 | 1191-1195 | 29719539 | denotes | 2018 |
| T38685 | 1937-1941 | 11905813 | denotes | 2001 |
| T58214 | 1958-1962 | 17312110 | denotes | 2007 |
| T1045 | 1983-1987 | 26919106 | denotes | 2016 |
| T59596 | 2005-2009 | 22615821 | denotes | 2012 |
| T22463 | 2723-2727 | 31316510 | denotes | 2019 |
| T69970 | 3620-3624 | 19587043 | denotes | 2009 |
| T60836 | 4100-4104 | 27670241 | denotes | 2017 |
| T91375 | 4315-4319 | 30778167 | denotes | 2019 |
| T21517 | 4474-4478 | 15080302 | denotes | 2004 |
| T58402 | 4916-4920 | 9486650 | denotes | 1998 |
| T11232 | 4937-4941 | 9034158 | denotes | 1997 |
| T15390 | 5043-5047 | 29302013 | denotes | 2018 |
| T84673 | 5742-5746 | 26251193 | denotes | 2015 |
| T83308 | 6076-6080 | 19559672 | denotes | 2009 |
| T78837 | 6139-6143 | 30524877 | denotes | 2017 |
| T62134 | 6694-6698 | 26727464 | denotes | 2016 |
| T45258 | 6716-6720 | 30770247 | denotes | 2019 |
| T84724 | 6927-6931 | 21946417 | denotes | 2011 |
| T32079 | 7088-7092 | 21623379 | denotes | 2011 |
| T18273 | 7259-7263 | 30414858 | denotes | 2019 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T154 | 16-21 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
| T155 | 38-43 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T156 | 78-83 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T157 | 144-148 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T158 | 167-171 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T159 | 271-276 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T160 | 383-391 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T161 | 386-391 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T162 | 416-424 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T163 | 419-424 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T164 | 442-447 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T165 | 474-482 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T166 | 529-534 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
| T167 | 567-572 | Body_part | denotes | Blood | http://purl.org/sig/ont/fma/fma9670 |
| T168 | 644-652 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T169 | 647-652 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T170 | 671-676 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T171 | 895-903 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T172 | 898-903 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T173 | 936-941 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T174 | 1012-1016 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T175 | 1017-1025 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T176 | 1020-1025 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T177 | 1129-1136 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T178 | 1132-1136 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T179 | 1276-1280 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T180 | 1281-1287 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T181 | 1335-1344 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T182 | 1365-1370 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T183 | 1467-1474 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T184 | 1470-1474 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T185 | 1507-1512 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T186 | 1520-1525 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T187 | 1560-1567 | Body_part | denotes | NK Cell | http://purl.org/sig/ont/fma/fma63147 |
| T188 | 1563-1567 | Body_part | denotes | Cell | http://purl.org/sig/ont/fma/fma68646 |
| T189 | 1610-1618 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T190 | 1613-1618 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T191 | 1759-1764 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T192 | 1795-1803 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T193 | 1871-1878 | Body_part | denotes | NK-cell | http://purl.org/sig/ont/fma/fma63147 |
| T194 | 1874-1878 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T195 | 2107-2112 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T196 | 2169-2176 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T197 | 2172-2176 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T198 | 2331-2338 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T199 | 2334-2338 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T200 | 2451-2456 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T201 | 2553-2561 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T202 | 2576-2584 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T203 | 2579-2584 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T204 | 2607-2612 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T205 | 2621-2629 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T206 | 2840-2843 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T207 | 2879-2891 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T208 | 2930-2935 | Body_part | denotes | ovary | http://purl.org/sig/ont/fma/fma7209 |
| T209 | 2942-2947 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T210 | 3009-3016 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T211 | 3012-3016 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T212 | 3111-3119 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T213 | 3150-3157 | Body_part | denotes | NK Cell | http://purl.org/sig/ont/fma/fma63147 |
| T214 | 3153-3157 | Body_part | denotes | Cell | http://purl.org/sig/ont/fma/fma68646 |
| T215 | 3199-3207 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T216 | 3202-3207 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T217 | 3224-3229 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T218 | 3409-3419 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
| T219 | 3536-3544 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T220 | 3539-3544 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T221 | 3576-3584 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T222 | 3579-3584 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T223 | 3627-3631 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T224 | 3632-3640 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T225 | 3635-3640 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T226 | 3805-3813 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T227 | 3808-3813 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T228 | 3829-3833 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T229 | 3901-3905 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T230 | 3948-3957 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
| T231 | 3967-3970 | Body_part | denotes | HLA | http://purl.org/sig/ont/fma/fma84795 |
| T232 | 4063-4068 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T233 | 4114-4128 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T234 | 4166-4173 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T235 | 4169-4173 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T236 | 4234-4241 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T237 | 4237-4241 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T238 | 4337-4345 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T239 | 4340-4345 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T240 | 4395-4400 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T241 | 4572-4583 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
| T242 | 4624-4632 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T243 | 4627-4632 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T244 | 4642-4647 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T245 | 4668-4675 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T246 | 4753-4761 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T247 | 4756-4761 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T248 | 4772-4777 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T249 | 4839-4843 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T250 | 4886-4889 | Body_part | denotes | HLA | http://purl.org/sig/ont/fma/fma84795 |
| T251 | 5009-5012 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T252 | 5128-5136 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T253 | 5131-5136 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T254 | 5241-5249 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T255 | 5244-5249 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T256 | 5328-5334 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T257 | 5422-5429 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T258 | 5425-5429 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T259 | 5642-5650 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T260 | 5645-5650 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T261 | 5782-5788 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T262 | 5888-5893 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T263 | 5923-5931 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
| T264 | 5978-5986 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T265 | 5981-5986 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T266 | 6039-6046 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T267 | 6042-6046 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T268 | 6183-6190 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T269 | 6186-6190 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T270 | 6284-6293 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T271 | 6307-6314 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T272 | 6310-6314 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T273 | 6362-6367 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T274 | 6438-6445 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T275 | 6441-6445 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T276 | 6671-6675 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T277 | 6766-6770 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T278 | 6874-6884 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
| T279 | 7004-7015 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T280 | 7023-7027 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T281 | 7144-7164 | Body_part | denotes | alveolar macrophages | http://purl.org/sig/ont/fma/fma83023 |
| T282 | 7358-7368 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
| T283 | 7369-7380 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T17 | 567-572 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T18 | 671-676 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T19 | 1012-1016 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T20 | 1276-1280 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T21 | 1281-1287 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T22 | 1507-1512 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T23 | 3224-3229 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T24 | 3627-3631 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T25 | 3829-3833 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T26 | 4063-4068 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T27 | 4395-4400 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T28 | 5888-5893 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T29 | 6671-6675 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T30 | 6766-6770 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T31 | 6874-6884 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
| T32 | 7023-7027 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T147 | 576-584 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T148 | 680-688 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T149 | 1155-1174 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T150 | 1165-1174 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T151 | 1250-1258 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T152 | 1374-1382 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T153 | 1529-1537 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T154 | 2087-2095 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T155 | 2191-2199 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T156 | 2263-2271 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T157 | 2274-2283 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T158 | 2662-2666 | Disease | denotes | ADCC | http://purl.obolibrary.org/obo/MONDO_0008734 |
| T159 | 2681-2700 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T160 | 2691-2700 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T161 | 2783-2787 | Disease | denotes | ADCC | http://purl.obolibrary.org/obo/MONDO_0008734 |
| T162 | 2822-2830 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T163 | 2866-2874 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T164 | 3073-3082 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T165 | 3129-3133 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T166 | 3170-3178 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T167 | 3181-3190 | Disease | denotes | Infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T168 | 3233-3241 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T169 | 3552-3561 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T170 | 3679-3687 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T171 | 3751-3759 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T172 | 4411-4419 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T173 | 4426-4434 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T174 | 4437-4446 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T175 | 4679-4687 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T176 | 4783-4791 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T177 | 5015-5024 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T178 | 5142-5150 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T179 | 5298-5306 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T180 | 5792-5800 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T181 | 6200-6204 | Disease | denotes | ADCC | http://purl.obolibrary.org/obo/MONDO_0008734 |
| T182 | 6342-6350 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T183 | 6459-6467 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T184 | 6519-6527 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T185 | 6530-6539 | Disease | denotes | Infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T186 | 6608-6616 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T187 | 6619-6628 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T188 | 6790-6809 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T189 | 6800-6809 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T190 | 7032-7041 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T191 | 7393-7401 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T192 | 7439-7447 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T193 | 7450-7459 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T173 | 0-21 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | Innate Lymphoid Cells |
| T174 | 22-43 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | Innate lymphoid cells |
| T175 | 45-49 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
| T176 | 78-83 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T177 | 142-148 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
| T178 | 165-171 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cell |
| T179 | 266-276 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | (NK) cells |
| T180 | 306-310 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
| T181 | 363-367 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T182 | 383-391 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T183 | 416-424 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T184 | 442-447 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T185 | 526-534 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK Cells |
| T186 | 567-572 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | Blood |
| T187 | 567-572 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | Blood |
| T188 | 644-652 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T189 | 671-676 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T190 | 671-676 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T191 | 827-828 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T192 | 864-865 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T193 | 895-903 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T194 | 936-941 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T195 | 1012-1016 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T196 | 1012-1016 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T197 | 1017-1025 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T198 | 1103-1106 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T199 | 1129-1136 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T200 | 1191-1195 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T201 | 1229-1231 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T202 | 1270-1275 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T203 | 1276-1280 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T204 | 1276-1280 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T205 | 1335-1344 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T206 | 1365-1370 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T207 | 1467-1474 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T208 | 1507-1512 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T209 | 1507-1512 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T210 | 1520-1525 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T211 | 1560-1567 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK Cell |
| T212 | 1568-1578 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | Activation |
| T213 | 1610-1618 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T214 | 1642-1652 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activating |
| T215 | 1744-1749 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T216 | 1759-1764 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T217 | 1781-1786 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T218 | 1871-1878 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK-cell |
| T219 | 1879-1889 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activating |
| T220 | 2107-2112 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T221 | 2169-2176 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T222 | 2177-2187 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T223 | 2331-2338 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T224 | 2339-2349 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T225 | 2358-2360 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T226 | 2451-2456 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T227 | 2576-2584 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T228 | 2607-2612 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T229 | 2922-2929 | http://purl.obolibrary.org/obo/NCBITaxon_10026 | denotes | hamster |
| T230 | 2930-2935 | http://www.ebi.ac.uk/efo/EFO_0000973 | denotes | ovary |
| T99383 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T232 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T233 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T234 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T235 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T236 | 2937-2940 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T237 | 2942-2947 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T238 | 3009-3016 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T239 | 3017-3027 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T240 | 3150-3157 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK Cell |
| T241 | 3199-3207 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T242 | 3224-3229 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T243 | 3224-3229 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T244 | 3316-3317 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T245 | 3536-3544 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T246 | 3562-3567 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T247 | 3576-3584 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T248 | 3627-3631 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T249 | 3627-3631 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T250 | 3632-3640 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T251 | 3805-3813 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T252 | 3823-3828 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T253 | 3829-3833 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T254 | 3829-3833 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T255 | 3842-3843 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T256 | 3901-3905 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T257 | 3942-3947 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T258 | 3991-3993 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T259 | 4003-4012 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T260 | 4026-4027 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T261 | 4063-4068 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T262 | 4063-4068 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T263 | 4166-4173 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T264 | 4234-4241 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T265 | 4337-4345 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T266 | 4395-4400 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T267 | 4395-4400 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T268 | 4624-4632 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T269 | 4642-4647 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T270 | 4753-4761 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T271 | 4766-4769 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T272 | 4770-4777 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T273 | 4839-4843 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T274 | 5043-5047 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T275 | 5050-5055 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | Genes |
| T276 | 5128-5136 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T277 | 5241-5249 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T278 | 5328-5334 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T279 | 5422-5429 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T280 | 5535-5538 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T281 | 5611-5612 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T282 | 5642-5650 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T283 | 5782-5788 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T284 | 5888-5893 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T285 | 5888-5893 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T286 | 5923-5931 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
| T287 | 5978-5986 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T288 | 6039-6046 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T289 | 6183-6190 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T290 | 6205-6208 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T291 | 6284-6293 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T292 | 6307-6314 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T293 | 6362-6367 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T294 | 6407-6416 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T295 | 6438-6445 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T296 | 6511-6515 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
| T297 | 6671-6675 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T298 | 6671-6675 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T299 | 6766-6770 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T300 | 6766-6770 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T301 | 6867-6873 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
| T302 | 6874-6884 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
| T303 | 7023-7027 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T304 | 7023-7027 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T305 | 7050-7056 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
| T306 | 7103-7107 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
| T307 | 7180-7181 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T308 | 7182-7184 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M1 |
| T309 | 7182-7184 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M1 |
| T310 | 7219-7220 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T311 | 7431-7435 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T102 | 69-77 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
| T103 | 123-130 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T104 | 1214-1221 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T105 | 1223-1228 | Chemical | denotes | CXCL9 | http://purl.obolibrary.org/obo/CHEBI_138154 |
| T106 | 1318-1324 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T107 | 1795-1803 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T108 | 1833-1840 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T109 | 2076-2083 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T110 | 2420-2428 | Chemical | denotes | antigens | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T111 | 2879-2891 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T112 | 3958-3965 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T113 | 4892-4900 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T114 | 5353-5355 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T116 | 5504-5506 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T118 | 5521-5523 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T120 | 5636-5641 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T121 | 5696-5707 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
| T122 | 5709-5711 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T124 | 5837-5843 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T125 | 5988-5991 | Chemical | denotes | Guo | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T126 | 6175-6177 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T128 | 6394-6396 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T130 | 6889-6895 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T131 | 6962-6964 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T133 | 7182-7184 | Chemical | denotes | M1 | http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826 |
| T137 | 7221-7223 | Chemical | denotes | M2 | http://purl.obolibrary.org/obo/CHEBI_34827|http://purl.obolibrary.org/obo/CHEBI_51112 |
| T139 | 7286-7288 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T16 | 2716-2721 | Phenotype | denotes | Moody | http://purl.obolibrary.org/obo/HP_0001575 |
| T17 | 3111-3125 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T92 | 55-68 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune |
| T93 | 474-493 | http://purl.obolibrary.org/obo/GO_0001816 | denotes | cytokine production |
| T94 | 1560-1578 | http://purl.obolibrary.org/obo/GO_0030101 | denotes | NK Cell Activation |
| T95 | 1735-1740 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | lysis |
| T96 | 2169-2187 | http://purl.obolibrary.org/obo/GO_0030101 | denotes | NK cell activation |
| T97 | 2172-2187 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | cell activation |
| T98 | 2218-2227 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T99 | 2331-2349 | http://purl.obolibrary.org/obo/GO_0030101 | denotes | NK cell activation |
| T100 | 2334-2349 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | cell activation |
| T101 | 2553-2572 | http://purl.obolibrary.org/obo/GO_0001816 | denotes | cytokine production |
| T102 | 2589-2594 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | lysis |
| T103 | 2662-2666 | http://purl.obolibrary.org/obo/GO_0001788 | denotes | ADCC |
| T104 | 2783-2787 | http://purl.obolibrary.org/obo/GO_0001788 | denotes | ADCC |
| T105 | 3009-3027 | http://purl.obolibrary.org/obo/GO_0030101 | denotes | NK cell activation |
| T106 | 3012-3027 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | cell activation |
| T107 | 3597-3606 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T108 | 3597-3606 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T109 | 4003-4012 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T110 | 4169-4185 | http://purl.obolibrary.org/obo/GO_0048468 | denotes | cell development |
| T111 | 5602-5623 | http://purl.obolibrary.org/obo/GO_0071613 | denotes | granzyme B production |
| T112 | 5709-5714 | http://purl.obolibrary.org/obo/GO_0004915 | denotes | IL-6R |
| T113 | 6039-6062 | http://purl.obolibrary.org/obo/GO_0001779 | denotes | NK cell differentiation |
| T114 | 6042-6062 | http://purl.obolibrary.org/obo/GO_0030154 | denotes | cell differentiation |
| T115 | 6200-6204 | http://purl.obolibrary.org/obo/GO_0001788 | denotes | ADCC |
| T116 | 6310-6326 | http://purl.obolibrary.org/obo/GO_0008037 | denotes | cell recognition |
| T117 | 6407-6416 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 680 | 400-414 | Gene | denotes | CD56brightCD16 | Gene:4684 |
| 681 | 497-509 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 683 | 576-584 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 702 | 1097-1102 | Gene | denotes | CXCR3 | Gene:2833 |
| 703 | 1208-1213 | Gene | denotes | CXCR3 | Gene:2833 |
| 704 | 1223-1231 | Gene | denotes | CXCL9-11 | Gene:4283 |
| 705 | 1312-1317 | Gene | denotes | CXCR3 | Gene:2833 |
| 706 | 1436-1441 | Gene | denotes | CXCR3 | Gene:2833 |
| 707 | 1513-1515 | Gene | denotes | to | Gene:6999 |
| 708 | 1118-1120 | Gene | denotes | to | Gene:6999 |
| 709 | 689-697 | Species | denotes | patients | Tax:9606 |
| 710 | 947-955 | Species | denotes | patients | Tax:9606 |
| 711 | 1270-1275 | Species | denotes | human | Tax:9606 |
| 712 | 1383-1391 | Species | denotes | patients | Tax:9606 |
| 713 | 1538-1546 | Species | denotes | patients | Tax:9606 |
| 714 | 1155-1164 | Species | denotes | influenza | Tax:11520 |
| 715 | 680-688 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 716 | 1165-1174 | Disease | denotes | infection | MESH:D007239 |
| 717 | 1250-1269 | Disease | denotes | SARS-CoV-2-infected | MESH:C000657245 |
| 718 | 1374-1382 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 719 | 1529-1537 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 745 | 1909-1914 | Gene | denotes | NKp46 | Gene:9437 |
| 746 | 2064-2075 | Gene | denotes | NK receptor | Gene:3804 |
| 747 | 2240-2244 | Gene | denotes | IgG3 | Gene:3502 |
| 748 | 2877-2878 | Gene | denotes | S | Gene:43740568 |
| 749 | 2800-2802 | Gene | denotes | to | Gene:6999 |
| 750 | 2460-2462 | Gene | denotes | to | Gene:6999 |
| 751 | 2409-2411 | Gene | denotes | to | Gene:6999 |
| 752 | 2122-2124 | Gene | denotes | to | Gene:6999 |
| 753 | 1721-1723 | Gene | denotes | to | Gene:6999 |
| 754 | 2866-2876 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 755 | 2914-2929 | Species | denotes | Chinese hamster | Tax:10029 |
| 756 | 2681-2690 | Species | denotes | influenza | Tax:11520 |
| 757 | 2822-2830 | Species | denotes | SARS-CoV | Tax:694009 |
| 758 | 1683-1695 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 759 | 1744-1758 | Disease | denotes | virus-infected | MESH:D001102 |
| 760 | 2087-2106 | Disease | denotes | SARS-CoV-2-infected | MESH:C000657245 |
| 761 | 2191-2199 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 762 | 2263-2283 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
| 763 | 2442-2450 | Disease | denotes | infected | MESH:D007239 |
| 764 | 2598-2606 | Disease | denotes | infected | MESH:D007239 |
| 765 | 2648-2660 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 766 | 2691-2700 | Disease | denotes | infection | MESH:D007239 |
| 767 | 3073-3082 | Disease | denotes | infection | MESH:D007239 |
| 768 | 3129-3133 | Disease | denotes | ARDS | MESH:D012128 |
| 769 | 2937-2940 | CellLine | denotes | CHO | CVCL:0213 |
| 771 | 3170-3190 | Disease | denotes | SARS-CoV-2 Infection | MESH:C000657245 |
| 794 | 3292-3298 | Gene | denotes | CD107a | Gene:3916 |
| 795 | 3300-3305 | Gene | denotes | Ksp37 | Gene:643236 |
| 796 | 3307-3317 | Gene | denotes | granzyme B | Gene:3002 |
| 797 | 3323-3333 | Gene | denotes | granulysin | Gene:10578 |
| 798 | 3421-3426 | Gene | denotes | IFN-ɣ | Gene:3458 |
| 799 | 3432-3437 | Gene | denotes | TNF-α | Gene:7124 |
| 800 | 3691-3695 | Gene | denotes | ACE2 | Gene:59272 |
| 801 | 3856-3859 | Gene | denotes | KIR | Gene:3805 |
| 802 | 3242-3250 | Species | denotes | patients | Tax:9606 |
| 803 | 3552-3567 | Species | denotes | influenza virus | Tax:11308 |
| 804 | 3679-3689 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 805 | 3751-3761 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 806 | 3823-3828 | Species | denotes | human | Tax:9606 |
| 807 | 4411-4421 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 808 | 4699-4707 | Species | denotes | patients | Tax:9606 |
| 809 | 3942-3947 | Species | denotes | human | Tax:9606 |
| 810 | 3233-3241 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 811 | 3349-3370 | Disease | denotes | impaired cytotoxicity | MESH:D064420 |
| 812 | 3739-3747 | Disease | denotes | infected | MESH:D007239 |
| 813 | 3906-3918 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 814 | 4431-4446 | Disease | denotes | CoV-1 infection | MESH:D018352 |
| 815 | 4679-4698 | Disease | denotes | SARS-CoV-2-infected | MESH:C000657245 |
| 852 | 4731-4736 | Gene | denotes | NKG2A | Gene:3821 |
| 853 | 4824-4829 | Gene | denotes | NKG2A | Gene:3821 |
| 854 | 4886-4891 | Gene | denotes | HLA-E | Gene:3133 |
| 855 | 5090-5094 | Gene | denotes | LAG3 | Gene:3902 |
| 856 | 5099-5103 | Gene | denotes | TIM3 | Gene:84868 |
| 857 | 5353-5357 | Gene | denotes | IL-6 | Gene:3569 |
| 858 | 5504-5508 | Gene | denotes | IL-6 | Gene:3569 |
| 859 | 5602-5612 | Gene | denotes | granzyme B | Gene:3002 |
| 860 | 5709-5714 | Gene | denotes | IL-6R | Gene:3570 |
| 861 | 5749-5754 | Gene | denotes | TNF-α | Gene:7124 |
| 862 | 5941-5946 | Gene | denotes | TNF-α | Gene:7124 |
| 863 | 6007-6012 | Gene | denotes | TNF-α | Gene:7124 |
| 864 | 6116-6121 | Gene | denotes | NKp46 | Gene:9437 |
| 865 | 6166-6171 | Gene | denotes | TNF-α | Gene:7124 |
| 866 | 6175-6179 | Gene | denotes | IL-6 | Gene:3569 |
| 867 | 6394-6398 | Gene | denotes | IL-6 | Gene:3569 |
| 868 | 6403-6406 | Gene | denotes | TNF | Gene:7124 |
| 869 | 6036-6038 | Gene | denotes | to | Gene:6999 |
| 870 | 6022-6024 | Gene | denotes | to | Gene:6999 |
| 871 | 5958-5960 | Gene | denotes | to | Gene:6999 |
| 872 | 5267-5269 | Gene | denotes | to | Gene:6999 |
| 873 | 4766-4769 | Gene | denotes | CD8 | Gene:925 |
| 874 | 4792-4800 | Species | denotes | patients | Tax:9606 |
| 875 | 5151-5159 | Species | denotes | patients | Tax:9606 |
| 876 | 5307-5315 | Species | denotes | patients | Tax:9606 |
| 877 | 5801-5809 | Species | denotes | patients | Tax:9606 |
| 878 | 6468-6476 | Species | denotes | patients | Tax:9606 |
| 879 | 5696-5707 | Chemical | denotes | tocilizumab | MESH:C502936 |
| 880 | 4783-4791 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 881 | 4844-4856 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 882 | 5009-5024 | Disease | denotes | HIV-1 infection | MESH:D015658 |
| 883 | 5142-5150 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 884 | 5298-5306 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 885 | 5792-5800 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 886 | 6342-6361 | Disease | denotes | SARS-CoV-2-infected | MESH:C000657245 |
| 887 | 6459-6467 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 889 | 6519-6539 | Disease | denotes | SARS-CoV-2 Infection | MESH:C000657245 |
| 905 | 6826-6838 | Gene | denotes | amphiregulin | Gene:11839 |
| 906 | 6962-6967 | Gene | denotes | IL-13 | Gene:3596 |
| 907 | 7286-7291 | Gene | denotes | IL-13 | Gene:3596 |
| 908 | 7016-7018 | Gene | denotes | to | Gene:6999 |
| 909 | 6982-6984 | Gene | denotes | to | Gene:6999 |
| 910 | 6552-6554 | Gene | denotes | to | Gene:6999 |
| 911 | 6813-6817 | Species | denotes | mice | Tax:10090 |
| 912 | 7402-7410 | Species | denotes | patients | Tax:9606 |
| 913 | 6790-6799 | Species | denotes | influenza | Tax:11520 |
| 914 | 7032-7041 | Species | denotes | influenza | Tax:11520 |
| 915 | 6889-6895 | Chemical | denotes | oxygen | MESH:D010100 |
| 916 | 6608-6628 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
| 917 | 6800-6809 | Disease | denotes | infection | MESH:D007239 |
| 918 | 7393-7401 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 919 | 7439-7459 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T119 | 0-21 | Sentence | denotes | Innate Lymphoid Cells |
| T120 | 22-188 | Sentence | denotes | Innate lymphoid cells (ILCs) are innate immune effector cells that lack the expression of rearranged antigen receptors (T cell receptor [TCR], B cell receptor [BCR]). |
| T121 | 189-369 | Sentence | denotes | The ILC family is divided into two main groups: the cytotoxic natural killer (NK) cells and the non-cytotoxic helper ILCs, which include ILC1, ILC2, and ILC3 (Vivier et al., 2018). |
| T122 | 370-524 | Sentence | denotes | Conventional NK cells include CD56brightCD16− NK cells and CD56dimCD16+ cells, which are specialized in cytokine production or cytotoxicity, respectively. |
| T123 | 526-593 | Sentence | denotes | NK Cells Are Decreased in the Peripheral Blood of COVID-19 patients |
| T124 | 594-826 | Sentence | denotes | Multiple studies have reported reduced numbers of NK cells in the peripheral blood of COVID-19 patients, which is associated with severity of the disease (Song et al., 2020, Wang et al., 2020f, Yu et al., 2020, Zheng et al., 2020b). |
| T125 | 827-995 | Sentence | denotes | A recent scRNA-seq analysis revealed a transcriptomic signature for NK cells that was equally represented in lungs from patients and healthy donors (Liao et al., 2020). |
| T126 | 996-1197 | Sentence | denotes | The majority of lung NK cells are non-resident (Gasteiger et al., 2015, Marquardt et al., 2017), and CXCR3 has been shown to mediate NK cell infiltration upon influenza infection (Carlin et al., 2018). |
| T127 | 1198-1412 | Sentence | denotes | In vitro, CXCR3 ligands (CXCL9-11) are increased in SARS-CoV-2-infected human lung tissue (Chu et al., 2020), and CXCR3-ligand-producing monocytes are expanded in the lungs of COVID-19 patients (Liao et al., 2020). |
| T128 | 1413-1558 | Sentence | denotes | This suggests that the CXCR3 pathway might facilitate NK cell recruitment from the peripheral blood to the lungs in COVID-19 patients (Figure 2). |
| T129 | 1560-1609 | Sentence | denotes | NK Cell Activation Pathways in Antiviral Immunity |
| T130 | 1610-1696 | Sentence | denotes | NK cells express inhibitory and activating receptors that regulate their cytotoxicity. |
| T131 | 1697-2011 | Sentence | denotes | They are therefore able to induce the lysis of virus-infected cells that upregulate virus-derived proteins, as well as stress-inducible ligands, which are then recognized by NK-cell-activating receptors, such as NKp46 (Cerwenka and Lanier, 2001, Draghi et al., 2007, Duev-Cohen et al., 2016, Glasner et al., 2012). |
| T132 | 2012-2208 | Sentence | denotes | Future studies should investigate the expression of NK receptor ligands on SARS-CoV-2-infected cells in order to better understand the mechanisms underlying NK cell activation in COVID-19 disease. |
| T133 | 2209-2516 | Sentence | denotes | Further, secretion of IgG1 and IgG3 antibodies during SARS-CoV-2 infection (Amanat et al., 2020) may induce CD56dim CD16+ NK cell activation through Fc receptor recognition of antibodies either bound to surface antigens expressed on infected cells or to extracellular virions as immune complexes (Figure 2). |
| T134 | 2517-2729 | Sentence | denotes | This interaction might trigger both cytokine production by NK cells and lysis of infected cells through antibody-mediated cellular cytotoxicity (ADCC), as shown in influenza infection (Von Holle and Moody, 2019). |
| T135 | 2730-2969 | Sentence | denotes | Emerging data highlight the capacity for NK-mediated ADCC in response to naturally isolated SARS-CoV-1 anti-S IgG that crossreacts with SARS-CoV-2 S glycoprotein when transfected into Chinese hamster ovary (CHO) cells (Pinto et al., 2020). |
| T136 | 2970-3134 | Sentence | denotes | These findings suggest that triggering NK cell activation may not only contribute to the resolution of infection, but also contribute to the cytokine storm in ARDS. |
| T137 | 3136-3190 | Sentence | denotes | Impairment of NK Cell Function in SARS-CoV-2 Infection |
| T138 | 3191-3479 | Sentence | denotes | Ex vivo NK cells from peripheral blood of COVID-19 patients have reduced intracellular expression of CD107a, Ksp37, granzyme B, and granulysin, suggesting an impaired cytotoxicity, as well as an impaired production of chemokines, IFN-ɣ, and TNF-α (Wilk et al., 2020, Zheng et al., 2020b). |
| T139 | 3480-3545 | Sentence | denotes | Several pathways may contribute to the dysregulation of NK cells. |
| T140 | 3546-3788 | Sentence | denotes | While influenza virus infects NK cells and induces apoptosis (Mao et al., 2009), lung NK cells do not express the entry receptor for SARS-CoV-2, ACE2, and are therefore unlikely to be directly infected by SARS-CoV-2 (Travaglini et al., 2020). |
| T141 | 3789-4106 | Sentence | denotes | The majority of NK cells found in human lung display a mature CD16+KIR+CD56dim phenotype and are able to induce cell cytotoxicity in response to loss of human leukocyte antigen (HLA) class I or through Fc receptor signaling, although to a lower extent than their peripheral blood counterpart (Marquardt et al., 2017). |
| T142 | 4107-4321 | Sentence | denotes | Killer-immunoglobulin receptors (KIRs) are acquired during NK cell development alongside CD16 (FcRγIIIA) and are essential for NK cell licensing and subsequent capacity for cytolytic function (Sivori et al., 2019). |
| T143 | 4322-4500 | Sentence | denotes | Frequencies of NK cells expressing CD16 and/or KIRs are decreased in the blood following SARS-CoV-2 and SARS-CoV-1 infection, respectively (Xia et al., 2004, Wang et al., 2020d). |
| T144 | 4501-4708 | Sentence | denotes | Collectively, the data suggest either an impaired maturation of the NK compartment or migration of the mature, circulating NK cells into the lungs or other peripheral tissues of SARS-CoV-2-infected patients. |
| T145 | 4709-4823 | Sentence | denotes | The immune checkpoint NKG2A is increased on NK cells and CD8 T cells from COVID-19 patients (Zheng et al., 2020b). |
| T146 | 4824-5049 | Sentence | denotes | NKG2A inhibits cell cytotoxicity by binding the non-classical HLA-E molecule (Braud et al., 1998, Brooks et al., 1997), and this interaction is strongly correlated with poor control of HIV-1 infection (Ramsuran et al., 2018). |
| T147 | 5050-5202 | Sentence | denotes | Genes encoding the inhibitory receptors LAG3 and TIM3 are also upregulated in NK cells from COVID-19 patients (Wilk et al., 2020, Hadjadj et al., 2020). |
| T148 | 5203-5283 | Sentence | denotes | Thus, increased immune checkpoints on NK cells might contribute to viral escape. |
| T149 | 5284-5479 | Sentence | denotes | Additionally, COVID-19 patients have higher plasma concentrations of IL-6 (Huang et al., 2020b), which significantly correlate with lower NK cell numbers (Wang et al., 2020d, Wang et al., 2020f). |
| T150 | 5480-5748 | Sentence | denotes | In vitro stimulation by IL-6 and soluble IL-6 receptor has previously revealed impaired cytolytic functions (perforin and granzyme B production) by healthy donor NK cells, which can be restored following addition of tocilizumab (IL-6R blockade) (Cifaldi et al., 2015). |
| T151 | 5749-6006 | Sentence | denotes | TNF-α is also upregulated in the plasma of COVID-19 patients (Huang et al., 2020b), and ligand-receptor interaction analysis of peripheral blood scRNA-seq data suggests that monocyte-secreted TNF-α might bind to its receptors on NK cells (Guo et al., 2020). |
| T152 | 6007-6230 | Sentence | denotes | TNF-α is known to contribute to NK cell differentiation (Lee et al., 2009), which includes downregulation of NKp46 (Ivagnès et al., 2017), though no effect of TNF-α or IL-6 on NK cell-mediated ADCC has been reported so far. |
| T153 | 6231-6488 | Sentence | denotes | Collectively, these data suggest that crosstalk with monocytes might impair NK cell recognition and killing of SARS-CoV-2-infected cells, and antibodies targeting IL-6 and TNF-signaling may benefit enhanced NK cell functions in COVID-19 patients (Figure 2). |
| T154 | 6490-6539 | Sentence | denotes | Relevance for Helper ILCs in SARS-CoV-2 Infection |
| T155 | 6540-6629 | Sentence | denotes | No studies, to date, have reported ILC1, ILC2, or ILC3 functions in SARS-CoV-2 infection. |
| T156 | 6630-6722 | Sentence | denotes | All three subsets are present in healthy lung (De Grove et al., 2016, Yudanin et al., 2019). |
| T157 | 6723-6933 | Sentence | denotes | ILC2s are essential for the improvement of lung function following influenza infection in mice through amphiregulin-mediated restoration of the airway epithelium and oxygen saturation (Monticelli et al., 2011). |
| T158 | 6934-7094 | Sentence | denotes | However, ILC2s also produce IL-13, contributing to the recruitment of macrophages to the lung and influenza-induced airway hyperreactivity (Chang et al., 2011). |
| T159 | 7095-7265 | Sentence | denotes | Indeed, ILCs are involved in the polarization of alveolar macrophages, either toward a M1-like phenotype (ILC1 and ILC3) or a M2-like phenotype (ILC2) (Kim et al., 2019). |
| T160 | 7266-7491 | Sentence | denotes | Given the increased IL-13 concentrations (Huang et al., 2020b) and the dysregulation of the macrophage compartment observed in COVID-19 patients, the role played by ILCs in SARS-CoV-2 infection warrants further investigation. |