PMC:7200337 / 20626-21074 JSONTXT

{"project":"2_test","denotations":[{"id":"32505227-28553293-46575269","span":{"begin":171,"end":175},"obj":"28553293"},{"id":"32505227-31140942-46575270","span":{"begin":199,"end":203},"obj":"31140942"},{"id":"32505227-32302401-46575271","span":{"begin":354,"end":358},"obj":"32302401"},{"id":"T5101","span":{"begin":171,"end":175},"obj":"28553293"},{"id":"T79329","span":{"begin":199,"end":203},"obj":"31140942"},{"id":"T2404","span":{"begin":354,"end":358},"obj":"32302401"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T148","span":{"begin":72,"end":76},"obj":"Body_part"},{"id":"T149","span":{"begin":100,"end":112},"obj":"Body_part"},{"id":"T150","span":{"begin":250,"end":260},"obj":"Body_part"},{"id":"T151","span":{"begin":273,"end":283},"obj":"Body_part"}],"attributes":[{"id":"A148","pred":"fma_id","subj":"T148","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A149","pred":"fma_id","subj":"T149","obj":"http://purl.org/sig/ont/fma/fma62854"},{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T16","span":{"begin":72,"end":76},"obj":"Body_part"}],"attributes":[{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T143","span":{"begin":116,"end":124},"obj":"Disease"}],"attributes":[{"id":"A143","pred":"mondo_id","subj":"T143","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T169","span":{"begin":72,"end":76},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T170","span":{"begin":72,"end":76},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T171","span":{"begin":153,"end":157},"obj":"http://purl.obolibrary.org/obo/CLO_0053428"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T89","span":{"begin":139,"end":151},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"666","span":{"begin":218,"end":220},"obj":"Gene"},{"id":"667","span":{"begin":28,"end":30},"obj":"Gene"},{"id":"668","span":{"begin":116,"end":126},"obj":"Species"},{"id":"669","span":{"begin":261,"end":268},"obj":"Disease"}],"attributes":[{"id":"A666","pred":"tao:has_database_id","subj":"666","obj":"Gene:6999"},{"id":"A667","pred":"tao:has_database_id","subj":"667","obj":"Gene:6999"},{"id":"A668","pred":"tao:has_database_id","subj":"668","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T116","span":{"begin":0,"end":205},"obj":"Sentence"},{"id":"T117","span":{"begin":206,"end":448},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019). In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2)."}