PMC:7200337 / 104523-106298 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-19198616-46575446 350-354 19198616 denotes 2009
32505227-30058403-46575447 388-392 30058403 denotes 2018
32505227-32155444-46575448 455-459 32155444 denotes 2020
32505227-19198616-46575449 629-633 19198616 denotes 2009
32505227-15878679-46575450 883-887 15878679 denotes 2005
32505227-15857975-46575451 901-905 15857975 denotes 2005
32505227-18832706-46575453 1554-1558 18832706 denotes 2008
32505227-26954467-46575454 1571-1575 26954467 denotes 2016
T46174 350-354 19198616 denotes 2009
T50934 388-392 30058403 denotes 2018
T45442 455-459 32155444 denotes 2020
T86111 629-633 19198616 denotes 2009
T47158 883-887 15878679 denotes 2005
T45218 901-905 15857975 denotes 2005
T57864 1554-1558 18832706 denotes 2008
T56463 1571-1575 26954467 denotes 2016

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T14 38-45 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T15 172-179 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 468-475 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T17 594-598 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T18 753-760 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T19 791-799 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T20 1148-1152 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T21 1176-1183 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T22 1231-1235 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T23 1291-1296 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T24 1335-1343 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T25 1359-1363 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26 1440-1445 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T27 1517-1522 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T28 1536-1541 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T29 1603-1607 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T597 6-14 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T598 139-148 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T599 269-278 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T600 314-322 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T601 429-437 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T602 687-695 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T603 698-707 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T604 950-959 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T605 1121-1129 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T606 1259-1268 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T607 1406-1415 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T608 1676-1684 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T60 46-49 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T61 180-183 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T62 388-392 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T63 401-404 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T64 476-479 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T65 592-598 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T66 639-645 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T67 1012-1015 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T68 1146-1152 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T69 1229-1235 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T70 1289-1296 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T71 1297-1303 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T72 1316-1324 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T73 1357-1363 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T74 1391-1393 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T75 1433-1436 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T76 1438-1445 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T77 1510-1513 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T78 1515-1522 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T79 1534-1541 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T80 1543-1545 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T81 1543-1545 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T82 1601-1607 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T83 1720-1721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T57903 38-45 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30408 172-179 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T21639 468-475 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T40595 753-760 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T85931 791-799 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T55851 1073-1075 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T49065 1176-1183 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38 1335-1343 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T96826 1543-1545 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T23755 1591-1600 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T13400 1758-1760 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T2 222-253 http://purl.obolibrary.org/obo/GO_0050778 denotes stimulating the immune response
T3 238-253 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T4 594-616 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T5 594-616 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T6 1350-1356 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7 1426-1432 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T8 1503-1509 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T9 1527-1533 http://purl.obolibrary.org/obo/GO_0007613 denotes memory

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3496 1433-1436 Gene denotes CD8 Gene:925
3497 1510-1513 Gene denotes CD4 Gene:12504
3498 466-467 Gene denotes S Gene:43740568
3499 931-933 Gene denotes to Gene:6999
3500 782-784 Gene denotes to Gene:6999
3501 715-717 Gene denotes to Gene:6999
3502 491-493 Gene denotes to Gene:6999
3503 116-118 Gene denotes to Gene:6999
3504 6-14 Species denotes SARS-CoV Tax:694009
3505 314-322 Species denotes SARS-CoV Tax:694009
3506 329-337 Species denotes MERS-CoV Tax:1335626
3507 429-439 Species denotes SARS-CoV-2 Tax:2697049
3508 1121-1129 Species denotes SARS-CoV Tax:694009
3509 1458-1462 Species denotes mice Tax:10090
3510 1645-1651 Species denotes people Tax:9606
3511 583-587 Chemical denotes nAbs
3512 734-738 Chemical denotes nAbs
3513 908-912 Chemical denotes nAbs
3514 135-148 Disease denotes CoV infection MESH:D018352
3515 269-278 Disease denotes infection MESH:D007239
3516 687-707 Disease denotes SARS-CoV-1 infection MESH:C000657245
3517 950-959 Disease denotes infection MESH:D007239
3518 1259-1268 Disease denotes infection MESH:D007239
3519 1350-1358 Disease denotes memory T MESH:D008569
3520 1406-1415 Disease denotes infection MESH:D007239
3521 1676-1684 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T628 0-149 Sentence denotes Since SARS-CoV-1 first emerged, the S protein has been favored as the most promising target for vaccine development to protect against CoV infection.
T629 150-461 Sentence denotes This particular viral protein has important roles in viral entry and in stimulating the immune response during natural infection and in vaccination studies of both SARS-CoV-1 and MERS-CoV (Du et al., 2009, Song et al., 2019, Zhou et al., 2018), which has also been confirmed for SARS-CoV-2 (Walls et al., 2020).
T630 462-635 Sentence denotes The S protein has been found to induce robust and protective humoral and cellular immunity, including the development of nAbs and T cell-mediated immunity (Du et al., 2009).
T631 636-1109 Sentence denotes In animal models, correlates of protection against SARS-CoV-1 infection appear to be induction of nAbs against the S protein, although antibodies to other proteins have been detected, such as those against nucleoprotein (N) and ORF3a (Qiu et al., 2005, Sui et al., 2005). nAbs are also believed to protect against infection by blocking receptor binding and viral entry, which has been shown with pseudovirus-based neutralization assays (Ni et al., 2020, Nie et al., 2020a).
T632 1110-1577 Sentence denotes Studies of SARS-CoV-1 indicate that T cell response against the S protein correlates with nAb titers and dominated the T cell response after natural infection, which also induced T cells active against the membrane (M) and N proteins, that memory T cell responses can persist even 11 years after infection, and that memory CD8+ T cells can protect mice from lethal challenge in the absence of memory CD4+ T cells and memory B cells (Li et al., 2008, Ng et al., 2016).
T633 1578-1775 Sentence denotes RBD-specific antiviral T cell responses have also been detected in people who have recovered from COVID-19, further validating its promise as a vaccine target (Braun et al., 2020, Ni et al., 2020).