PMC:7200337 / 102047-103276 JSONTXT

{"project":"2_test","denotations":[{"id":"32505227-32253318-46575443","span":{"begin":502,"end":506},"obj":"32253318"},{"id":"32505227-32281317-46575444","span":{"begin":1139,"end":1143},"obj":"32281317"},{"id":"T98365","span":{"begin":502,"end":506},"obj":"32253318"},{"id":"T99026","span":{"begin":1139,"end":1143},"obj":"32281317"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T5","span":{"begin":41,"end":47},"obj":"Body_part"},{"id":"T6","span":{"begin":216,"end":220},"obj":"Body_part"},{"id":"T7","span":{"begin":507,"end":512},"obj":"Body_part"},{"id":"T8","span":{"begin":538,"end":548},"obj":"Body_part"},{"id":"T9","span":{"begin":695,"end":703},"obj":"Body_part"},{"id":"T10","span":{"begin":891,"end":896},"obj":"Body_part"},{"id":"T11","span":{"begin":1163,"end":1168},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma9576"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T100","span":{"begin":507,"end":512},"obj":"Body_part"},{"id":"T101","span":{"begin":891,"end":896},"obj":"Body_part"},{"id":"T102","span":{"begin":1163,"end":1168},"obj":"Body_part"}],"attributes":[{"id":"A100","pred":"uberon_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A101","pred":"uberon_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A102","pred":"uberon_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T587","span":{"begin":59,"end":67},"obj":"Disease"},{"id":"T588","span":{"begin":573,"end":588},"obj":"Disease"},{"id":"T589","span":{"begin":637,"end":645},"obj":"Disease"}],"attributes":[{"id":"A587","pred":"mondo_id","subj":"T587","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A588","pred":"mondo_id","subj":"T588","obj":"http://purl.obolibrary.org/obo/MONDO_0003783"},{"id":"A589","pred":"mondo_id","subj":"T589","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T24","span":{"begin":41,"end":47},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T25","span":{"begin":110,"end":112},"obj":"http://purl.obolibrary.org/obo/PR_000005794"},{"id":"T26","span":{"begin":164,"end":166},"obj":"http://purl.obolibrary.org/obo/CLO_0009715"},{"id":"T27","span":{"begin":183,"end":185},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T28","span":{"begin":419,"end":421},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T29","span":{"begin":425,"end":427},"obj":"http://purl.obolibrary.org/obo/CLO_0009715"},{"id":"T30","span":{"begin":507,"end":512},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T31","span":{"begin":602,"end":606},"obj":"http://purl.obolibrary.org/obo/CLO_0008947"},{"id":"T32","span":{"begin":602,"end":606},"obj":"http://purl.obolibrary.org/obo/CLO_0050140"},{"id":"T33","span":{"begin":752,"end":754},"obj":"http://purl.obolibrary.org/obo/CLO_0009715"},{"id":"T34","span":{"begin":791,"end":793},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T35","span":{"begin":891,"end":896},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T36","span":{"begin":957,"end":959},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"},{"id":"T37","span":{"begin":1002,"end":1004},"obj":"http://purl.obolibrary.org/obo/PR_000005794"},{"id":"T38","span":{"begin":1083,"end":1085},"obj":"http://purl.obolibrary.org/obo/CLO_0054055"},{"id":"T39","span":{"begin":1086,"end":1088},"obj":"http://purl.obolibrary.org/obo/CLO_0009715"},{"id":"T40","span":{"begin":1099,"end":1101},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T41","span":{"begin":1163,"end":1168},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T42","span":{"begin":1181,"end":1183},"obj":"http://purl.obolibrary.org/obo/CLO_0009715"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T51573","span":{"begin":110,"end":112},"obj":"Chemical"},{"id":"T93279","span":{"begin":1002,"end":1004},"obj":"Chemical"}],"attributes":[{"id":"A60526","pred":"chebi_id","subj":"T51573","obj":"http://purl.obolibrary.org/obo/CHEBI_3380"},{"id":"A43422","pred":"chebi_id","subj":"T51573","obj":"http://purl.obolibrary.org/obo/CHEBI_73461"},{"id":"A98924","pred":"chebi_id","subj":"T93279","obj":"http://purl.obolibrary.org/obo/CHEBI_3380"},{"id":"A25552","pred":"chebi_id","subj":"T93279","obj":"http://purl.obolibrary.org/obo/CHEBI_73461"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T58","span":{"begin":573,"end":588},"obj":"Phenotype"},{"id":"T59","span":{"begin":648,"end":655},"obj":"Phenotype"}],"attributes":[{"id":"A58","pred":"hp_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/HP_0001888"},{"id":"A59","pred":"hp_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/HP_0020071"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":759,"end":770},"obj":"http://purl.obolibrary.org/obo/GO_0009056"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-PubTator","denotations":[{"id":"3362","span":{"begin":1002,"end":1004},"obj":"Gene"},{"id":"3363","span":{"begin":110,"end":112},"obj":"Gene"},{"id":"3364","span":{"begin":77,"end":84},"obj":"Species"},{"id":"3365","span":{"begin":148,"end":156},"obj":"Species"},{"id":"3366","span":{"begin":268,"end":276},"obj":"Species"},{"id":"3367","span":{"begin":409,"end":417},"obj":"Species"},{"id":"3368","span":{"begin":559,"end":567},"obj":"Species"},{"id":"3369","span":{"begin":614,"end":622},"obj":"Species"},{"id":"3370","span":{"begin":661,"end":669},"obj":"Species"},{"id":"3371","span":{"begin":716,"end":724},"obj":"Species"},{"id":"3372","span":{"begin":736,"end":744},"obj":"Species"},{"id":"3373","span":{"begin":920,"end":927},"obj":"Species"},{"id":"3374","span":{"begin":940,"end":948},"obj":"Species"},{"id":"3375","span":{"begin":1048,"end":1056},"obj":"Species"},{"id":"3376","span":{"begin":1066,"end":1074},"obj":"Species"},{"id":"3377","span":{"begin":378,"end":381},"obj":"Chemical"},{"id":"3378","span":{"begin":573,"end":588},"obj":"Disease"},{"id":"3379","span":{"begin":637,"end":655},"obj":"Disease"},{"id":"3381","span":{"begin":59,"end":67},"obj":"Disease"}],"attributes":[{"id":"A3362","pred":"tao:has_database_id","subj":"3362","obj":"Gene:1356"},{"id":"A3363","pred":"tao:has_database_id","subj":"3363","obj":"Gene:1356"},{"id":"A3364","pred":"tao:has_database_id","subj":"3364","obj":"Tax:9606"},{"id":"A3365","pred":"tao:has_database_id","subj":"3365","obj":"Tax:9606"},{"id":"A3366","pred":"tao:has_database_id","subj":"3366","obj":"Tax:9606"},{"id":"A3367","pred":"tao:has_database_id","subj":"3367","obj":"Tax:9606"},{"id":"A3368","pred":"tao:has_database_id","subj":"3368","obj":"Tax:9606"},{"id":"A3369","pred":"tao:has_database_id","subj":"3369","obj":"Tax:9606"},{"id":"A3370","pred":"tao:has_database_id","subj":"3370","obj":"Tax:9606"},{"id":"A3371","pred":"tao:has_database_id","subj":"3371","obj":"Tax:9606"},{"id":"A3372","pred":"tao:has_database_id","subj":"3372","obj":"Tax:9606"},{"id":"A3373","pred":"tao:has_database_id","subj":"3373","obj":"Tax:9606"},{"id":"A3374","pred":"tao:has_database_id","subj":"3374","obj":"Tax:9606"},{"id":"A3375","pred":"tao:has_database_id","subj":"3375","obj":"Tax:9606"},{"id":"A3376","pred":"tao:has_database_id","subj":"3376","obj":"Tax:9606"},{"id":"A3378","pred":"tao:has_database_id","subj":"3378","obj":"MESH:D008231"},{"id":"A3379","pred":"tao:has_database_id","subj":"3379","obj":"MESH:C000657245"},{"id":"A3381","pred":"tao:has_database_id","subj":"3381","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}

{"project":"LitCovid-sentences","denotations":[{"id":"T598","span":{"begin":0,"end":76},"obj":"Sentence"},{"id":"T599","span":{"begin":77,"end":138},"obj":"Sentence"},{"id":"T600","span":{"begin":139,"end":294},"obj":"Sentence"},{"id":"T601","span":{"begin":295,"end":315},"obj":"Sentence"},{"id":"T602","span":{"begin":316,"end":377},"obj":"Sentence"},{"id":"T603","span":{"begin":378,"end":398},"obj":"Sentence"},{"id":"T604","span":{"begin":399,"end":506},"obj":"Sentence"},{"id":"T605","span":{"begin":507,"end":524},"obj":"Sentence"},{"id":"T606","span":{"begin":525,"end":589},"obj":"Sentence"},{"id":"T607","span":{"begin":590,"end":622},"obj":"Sentence"},{"id":"T608","span":{"begin":623,"end":669},"obj":"Sentence"},{"id":"T609","span":{"begin":670,"end":724},"obj":"Sentence"},{"id":"T610","span":{"begin":725,"end":871},"obj":"Sentence"},{"id":"T611","span":{"begin":872,"end":890},"obj":"Sentence"},{"id":"T612","span":{"begin":891,"end":908},"obj":"Sentence"},{"id":"T613","span":{"begin":909,"end":1021},"obj":"Sentence"},{"id":"T614","span":{"begin":1022,"end":1056},"obj":"Sentence"},{"id":"T615","span":{"begin":1057,"end":1143},"obj":"Sentence"},{"id":"T616","span":{"begin":1144,"end":1162},"obj":"Sentence"},{"id":"T617","span":{"begin":1163,"end":1180},"obj":"Sentence"},{"id":"T618","span":{"begin":1181,"end":1229},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients\nPatient Characteristics Start of CP Therapy Results Reference\n5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020\nclinical improvement\nviral loads became negative within 12 days of the transfusion\nnAb titers increased\n10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020\nchest CT improved\nelevation of lymphocyte counts in patients with lymphocytopenia.\nincrease in SaO2 in all patients\nresolution of SARS-CoV-2 viremia in 7 patients\nincrease in neutralizing antibody titers in 5 patients\n4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b\nreduced viral load\nchest CT improved\n1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020\nclinical improvement of 2 patients\n2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020\nreduced viral load\nchest CT improved\nyo, years old; dpo, days post onset of symptoms."}